Pyridoindole antioxidant-induced preservation of rat hippocampal pyramidal cell number linked with reduction of oxidative stress yet without influence on cognitive deterioration in Alzheimer-like neurodegeneration

Neuroendocrinology Letters

Volumn 35, Issue 6, 2014, Pages 454-462

  Gasparova, Zdenka ^a   Stara, Veronika ^a   Janega, Pavol ^b,c   Navarova, Jana ^a   Sedlackova, Natalia ^a   Mach, Mojmir ^a   Ujhazy, Eduard ^a  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^b Faculty of Medicine of Comenius University and University Hospital Bratislava   (Slovakia)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Alzheimer disease; Learning performance; Lipid peroxidation; Lysosomal enzyme; Pyramidal cells; Rat hippocampus; Trimethyltin model

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; MALONALDEHYDE; N ACETYL BETA GLUCOSAMINIDASE; NEUROPROTECTIVE AGENT; PYRIDOINDOLE; UNCLASSIFIED DRUG; ACETYLGLUCOSAMINIDASE; INDOLE DERIVATIVE; PYRIDINE DERIVATIVE; SME1EC2;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; LEARNING; LIPID PEROXIDATION; MALE; MAZE TEST; MENTAL DETERIORATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PYRAMIDAL NERVE CELL; RAT; REFERENCE MEMORY; SPATIAL MEMORY; ANIMAL; COGNITION DISORDERS; DISEASE MODEL; DRUG EFFECTS; HIPPOCAMPAL CA1 REGION; METABOLISM; NERVE DEGENERATION; PATHOLOGY; WISTAR RAT;

ACETYLGLUCOSAMINIDASE; ALZHEIMER DISEASE; ANIMALS; ANTIOXIDANTS; CA1 REGION, HIPPOCAMPAL; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; INDOLES; MALE; MALONDIALDEHYDE; MAZE LEARNING; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PYRAMIDAL CELLS; PYRIDINES; RATS, WISTAR;

EID: 84922544603     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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