FK506-protective effects against trimethyltin neurotoxicity in rats: Hippocampal expression analyses reveal the involvement of periarterial osteopontin

Neuroscience

Volumn 153, Issue 4, 2008, Pages 1135-1145

  Morita, M ^a   Imai, H ^b   Liu, Y ^c   Xu, X ^c   Sadamatsu, M ^d   Nakagami, R ^c   Shirakawa, T ^a   Nakano, K ^a   Kita, Y ^e   Yoshida, K ^a   Tsunashima, K ^c   Kato, N ^c  

^a ASTELLAS PHARMA INC   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^e PFIZER INC   (United States)

Author keywords

FK506; hippocampal CA1 subregion; microarray; osteopontin; periarterial area; trimethyltin

Indexed keywords

GLUTATHIONE TRANSFERASE; LYSOZYME; OSTEOCALCIN; OSTEOPONTIN; TACROLIMUS;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MICROARRAY ANALYSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNINDEXED SEQUENCE; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOSUPPRESSIVE AGENTS; IN SITU NICK-END LABELING; MALE; MICROARRAY ANALYSIS; NEUROTOXICITY SYNDROMES; OSTEOPONTIN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TACROLIMUS; TIME FACTORS; TRIMETHYLTIN COMPOUNDS;

EID: 43949115521     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.01.078     Document Type: Article

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