BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes

Tissue Engineering - Part C: Methods

Volumn 21, Issue 2, 2015, Pages 133-147

  Ollitrault, David ^a   Legendre, Florence ^a   Drougard, Carole ^a,b   Briand, Mélanie ^c   Benateau, Hervé ^a   Goux, Didier ^c   Chajra, Hanane ^d   Poulain, Laurent ^c   Hartmann, Daniel ^e   Vivien, Denis ^f   Shridhar, Vijayalakshmi ^g   Baldi, Alfonso ^h   Mallein Gerin, Frédéric ⁱ   Boumediene, Karim ^a   Demoor, Magali ^a   Galera, Philippe ^a  

^a UNIVERSITÉ DE CAEN   (France)

^b Laboratory of Anatomy Pathology University Medical Center   (France)

^c Biology and Innovative Therapeutics for Ovarian Cancers group   (France)

^d Symatese Biomatériaux   (France)

^e UNIVERSITÉ DE LYON   (France)

^f INSERM   (France)

^g Mayo Clinic College of Medicine   (United States)

^h UNIVERSITY OF NAPLES FEDERICO II   (Italy)

ⁱ INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CARTILAGE; COLLAGEN; DEGRADATION; JOINTS (ANATOMY); NUCLEIC ACIDS; RESTORATION; SCAFFOLDS (BIOLOGY);

ARTICULAR CARTILAGES; AUTOLOGOUS CHONDROCYTE IMPLANTATIONS; BONE MORPHOGENETIC PROTEINS; CHONDROCYTE REDIFFERENTIATION; INNOVATIVE STRATEGIES; PUBLIC HEALTH ISSUES; SMALL INTERFERING RNA; TREATMENT CONDITIONS;

BODY FLUIDS;

BIOLOGICAL MARKER; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN SPONGE; COLLAGEN TYPE 1; HTRA1 SERINE PROTEASE; MESSENGER RNA; SERINE PROTEINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; COLLAGEN TYPE I, ALPHA 1 CHAIN; HTRA1 PROTEIN, HUMAN; HYALIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL DEDIFFERENTIATION; CELL HYPOXIA; COL1A1 GENE; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENETIC TRANSFECTION; HTRA1 GENE; HUMAN; HUMAN CELL; HYALINE CARTILAGE; IN VITRO STUDY; IN VIVO CULTURE; MOUSE; NONHUMAN; OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ARTICULAR CARTILAGE; BONE DEVELOPMENT; BOVINE; CELL CULTURE; CHONDROGENESIS; CYTOLOGY; DRUG EFFECTS; EXTRACELLULAR MATRIX; GENETICS; HYPERTROPHY; KINETICS; METABOLISM; MIDDLE AGED; NUDE MOUSE; VERY ELDERLY;

MUS MUSCULUS;

AGED; AGED, 80 AND OVER; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CARTILAGE, ARTICULAR; CATTLE; CELL HYPOXIA; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; HUMANS; HYALIN; HYPERTROPHY; KINETICS; MICE, NUDE; MIDDLE AGED; OSTEOGENESIS; PHENOTYPE; RNA, MESSENGER; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES;

EID: 84922526292     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2013.0724     Document Type: Article

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