The influence of scaffold architecture on chondrocyte distribution and behavior in matrix-associated chondrocyte transplantation grafts

Biomaterials

Volumn 32, Issue 4, 2011, Pages 1032-1040

  Nuernberger, Sylvia ^a,b   Cyran, Norbert ^c   Albrecht, Christian ^a   Redl, Heinz ^b   Vécsei, Vilmos ^a   Marlovits, Stefan ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Adhesion; Chondrocytes; Collagen; Hyaluronan; Scaffolds; Transplantation

Indexed keywords

CARTILAGE REGENERATION; CARTILAGE TISSUE ENGINEERING; CELL DIAMETERS; CELL DISTRIBUTION; CELL EXTENSION; CELL SHAPES; CELLULAR ADHESION; CHONDROCYTES; HYALURONAN; IN-CELL; IN-VITRO; MATERIAL COMPOSITIONS; MATRIX; SEM; TEM; TRANSPLANTATION;

ADHESION; ARCHITECTURE; BODY FLUIDS; CARTILAGE; CELL CULTURE; COLLAGEN; FIBERS; GRAFTS; TISSUE ENGINEERING;

SCAFFOLDS;

ARTICLE; CARTILAGE CELL; CELL ADHESION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SHAPE; CELL ULTRASTRUCTURE; CHONDROCYTE IMPLANTATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MATERIALS TESTING; PARTICLE SIZE; PHENOTYPE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TISSUE REGENERATION;

BIOCOMPATIBLE MATERIALS; CARTILAGE; CELL ADHESION; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; EXTRACELLULAR MATRIX; HUMANS; HYALURONIC ACID; MATERIALS TESTING; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSPLANTS;

EID: 78649451431     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.100     Document Type: Article

References (61)

1. Mayne R., Vail M.S., Mayne P.M., Miller E.J. Changes in type of collagen synthesized as clones of chick chondrocytes grow and eventually lose division capacity. Proc Natl Acad Sci U S A 1976, 73:1674-1678.
2. Marlovits S., Hombauer M., Tamandl D., Vécsei V., Schlegel W. Quantitative analysis of gene expression in human articular chondrocytes in monolayer culture. Int J Mol Med 2004, 13:281-287.
3. Schnabel M., Marlovits S., Eckhoff G., Fichtel I., Gotzen L., Vecsei V., et al. Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture. Osteoarthr Cartil 2002, 10:62-70.
4. Sokoloff L. In vitro culture of joint and articular tissue. The joint and synovial fluid 1980, vol. II:1-26. Academic Press, New York. L. Sokoloff (Ed.).
5. Benya P.D., Shaffer J.D. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 1982, 30:215-224.
6. Carver S.E., Heath C.A. Influence of intermittent pressure, fluid flow, and mixing on the regenerative properties of articular chondrocytes. Biotechnol Bioeng 1999, 65:274-281.
7. Buschmann M.D., Gluzband Y.A., Grodzinsky A.J., Hunziker E.B. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci 1995, 108:1497-1508.
8. Kawanishi M., Oura A., Furukawa K., Fukubayashi T., Nakamura K., Tateishi T., et al. Redifferentiation of dedifferentiated bovine articular chondrocytes enhanced by cyclic hydrostatic pressure under a gas-controlled system. Tissue Eng 2007, 13:957-964.
9. Kurz B., Domm C., Jin M., Sellckau R., Schunke M. Tissue engineering of articular cartilage under the influence of collagen I/III membranes and low oxygen tension. Tissue Eng 2004, 10:1277-1286.
10. Malda J., van Blitterswijk C.A., van Geffen M., Martens D.E., Tramper J., Riesle J. Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes. Osteoarthr Cartil 2004, 12:306-313.
11. Gaissmaier C., Koh J.L., Weise K. Growth and differentiation factors for cartilage healing and repair. Injury 2008, 39:S88-S96.
12. Chung C., Burdick J.A. Engineering cartilage tissue. Adv Drug Deliv Rev 2008, 60:243-262.
13. Getgood A., Brooks R., Fortier L., Rushton N. Articular cartilage tissue engineering: today's research, tomorrow's practice?. J Bone Joint Surg Br 2009, 91:565-576.
14. Ehlers E.M., Fuss M., Rohwedel J., Russlies M., Kuhnel W., Behrens P. Development of a biocomposite to fill out articular cartilage lesions. Light, scanning and transmission electron microscopy of sheep chondrocytes cultured on a collagen I/III sponge. Anat Anz 1999, 181:513-518.
15. Nehrer S., Breinan H.A., Ramappa A., Shortkroff S., Young G., Minas T., et al. Canine chondrocytes seeded in type I and type II collagen implants investigated in vitro. J Biomed Mater Res 1997, 38:95-104.
16. Marlovits S., Kutscha-Lissberg F., Aldrian S., Resinger C., Singer P., Zeller P., et al. Autologous chondrocyte transplantation for the treatment of articular cartilage defects in the knee joint. Techniques and results. Radiologe 2004, 44:763-772.
17. Haddo O., Mahroof S., Higgs D., David L., Pringle J., Bayliss M., et al. The use of chondrogide membrane in autologous chondrocyte implantation. Knee 2004, 11:51-55.
18. Marcacci M., Berruto M., Brocchetta D., Delcogliano A., Ghinelli D., Gobbi A., et al. Articular cartilage engineering with hyalograft C: 3-year clinical results. Clin Orthop Relat Res 2005, 423:96-105.
19. Erggelet C., Sittinger M., Lahm A. The arthroscopic implantation of autologous chondrocytes for the treatment of full-thickness cartilage defects of the knee joint. Arthroscopy 2003, 19:108-110.
20. Jasionowski M., Krzyminski K., Chrisler W., Markille L.M., Morris J., Gutowska A. Thermally-reversible gel for 3-D cell culture of chondrocytes. J Mater Sci Mater Med 2004, 15:575-582.
21. Hoemann C.D., Sun J., Legare A., McKee M.D., Buschmann M.D. Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. Osteoarthr Cartil 2005, 13:318-329.
22. Wang Y., Blasioli D.J., Kim H.J., Kim H.S., Kaplan D.L. Cartilage tissue engineering with silk scaffolds and human articular chondrocytes. Biomaterials 2006, 27:4434-4442.
23. Muller F.A., Muller L., Hofmann I., Greil P., Wenzel M.M., Staudenmaier R. Cellulose-based scaffold materials for cartilage tissue engineering. Biomaterials 2006, 27:3955-3963.
24. Song E., Yeon K.S., Chun T., Byun H.J., Lee Y.M. Collagen scaffolds derived from a marine source and their biocompatibility. Biomaterials 2006, 27:2951-2961.
25. Brittberg M., Nilsson A., Lindahl A., Ohlsson C., Peterson L. Rabbit articular cartilage defects treated with autologous cultured chondrocytes. Clin Orthop Relat Res 1996, 326:270-283.
26. Allemann F., Mizuno S., Eid K., Yates K.E., Zaleske D., Glowacki J. Effects of hyaluronan on engineered articular cartilage extracellular matrix gene expression in 3-dimensional collagen scaffolds. J Biomed Mater Res 2001, 55:13-19.
27. van Susante J.L.C., Pieper J., Buma P., van Kuppevelt T.H., van Beuningen H., Der Kraan P.M., et al. Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro. Biomaterials 2001, 22:2359-2369.
28. Ma Z., Mao Z., Gao C. Surface modification and property analysis of biomedical polymers used for tissue engineering. Colloids Surf B Biointerfaces 2007, 60:137-157.
29. Vasita R., Shanmugam I.K., Katt D.S. Improved biomaterials for tissue engineering applications: surface modification of polymers. Curr Top Med Chem 2008, 8:341-353.
30. Lao L., Tan H., Wang Y., Gao C. Chitosan modified poly(l-lactide) microspheres as cell microcarriers for cartilage tissue engineering. Colloids Surf B Biointerfaces 2008, 66:218-225.
31. Freeman J.W., Wright L.D., Laurencin C.T., Bhattacharyya S. Nanofabrication techniques. Biomedical nanostructures 2008, 3-24. John Wiley & Sons, Inc., Hoboken, New Jersey. K.E. Gonsalves, C.R. Halberstadt, C.T. Laurencin, L.S. Nair (Eds.).
32. Woodfield T.B., Malda J., de Wijn J., Peters F., Riesle J., van Blitterswijk C.A. Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique. Biomaterials 2004, 25:4149-4161.
33. Bryant S.J., Cuy J.L., Hauch K.D., Ratner B.D. Photo-patterning of porous hydrogels for tissue engineering. Biomaterials 2007, 28:2978-2986.
34. Steinert A.F., Noth U., Tuan R.S. Concepts in gene therapy for cartilage repair. Injury 2008, 39:S97-S113.
35. Elder B.D., Athanasiou K.A. Hydrostatic pressure in articular cartilage tissue engineering: from chondrocytes to tissue regeneration. Tissue Eng Part B Rev 2009, 15:43-53.
36. Waldman S.D., Couto D.C., Grynpas M.D., Pilliar R.M., Kandel R.A. Multi-axial mechanical stimulation of tissue engineered cartilage: review. Eur Cell Mater 2007, 13:66-73.
37. El Tamer M.K., Reis R.L. Progenitor and stem cells for bone and cartilage regeneration. J Tissue Eng Regen Med 2009, 3:327-337.
38. Chaipinyo K., Oakes B.W., Van Damme M.P. The use of debrided human articular cartilage for autologous chondrocyte implantation: maintenance of chondrocyte differentiation and proliferation in type I collagen gels. J Orthop Res 2004, 22:446-455.
39. Marlovits S., Tichy B., Truppe M., Gruber D., Vécsei V. Chondrogenesis of aged human articular cartilage in a scaffold-free bioreactor. Tissue Eng 2003, 9:1215-1226.
40. Hunziker E.B., Herrmann W., Schenk R.K. Improved cartilage fixation by ruthenium hexammine trichloride (RHT). A prerequisite for morphometry in growth cartilage. J Ultrastruct Res 1982, 81:1-12.
41. Knudson W., Aguiar D.J., Hua Q., Knudson C.B. CD44-anchored hyaluronan-rich pericellular matrices: an ultrastructural and biochemical analysis. Exp Cell Res 1996, 228:216-228.
42. Russlies M., Behrens P., Wunsch L., Gille J., Ehlers E.M. A cell-seeded biocomposite for cartilage repair. Ann Anat 2002, 184:317-323.
43. ®. Basic science, clinical repair and reconstruction of articular cartilage defects: current status and prospects 2006, 695-704. Timeo, Bologna. S. Zanasi, M. Brittberg, S. Nehrer, M. Marcacci (Eds.).
44. Schlegel W., Nürnberger S., Hombauer M., Albrecht C., Vecsei V., Marlovits S. Scaffold dependent differentiation of human articular chondrocytes. Osteoarthr Cartil 2008, 22:691-699.
45. Schinagl R.M., Kurtis M.S., Ellis K.D., Chien S., Sah R.L. Effect of seeding duration on the strength of chondrocyte adhesion to articular cartilage. J Orthop Res 1999, 17:121-129.
46. Nobes C.D., Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995, 81:53-62.
47. Small J.V., Resch G.P. The comings and goings of actin: coupling protrusion and retraction in cell motility. Curr Opin Cell Biol 2005, 17:517-523.
48. Knudson W., Loeser R.F. CD44 and integrin matrix receptors participate in cartilage homeostasis. Cell Mol Life Sci 2002, 59:36-44.
49. Chen C.S., Tan J., Tien J. Mechanotransduction at cell-matrix and cell-cell contacts. Annu Rev Biomed Eng 2004, 6:275-302.
50. Knudson C.B., Knudson W. Hyaluronan-binding proteins in development, tissue homeostasis, and disease. FASEB J 1993, 7:1233-1241.
51. Albrecht C., Schlegel W., Eckl P., Jagersberger T., Sadeghi K., Berger A., et al. Alterations in CD44 isoforms and HAS expression in human articular chondrocytes during the de- and re-differentiation processes. Int J Mol Med 2009, 23:253-259.
52. Loeser R.F. Chondrocyte integrin expression and function. Biorheology 2000, 37:109-116.
53. Shakibaei M., Zimmermann B., Merker H.J. Changes in integrin expression during chondrogenesis in vitro: an immunomorphological study. J Histochem Cytochem 1995, 43:1061-1069.
54. Park G.E., Pattison M.A., Park K., Webster T.J. Accelerated chondrocyte functions on NaOH-treated PLGA scaffolds. Biomaterials 2005, 26:3075-3082.
55. Burns K., Yao C., Webster T.J. Increased chondrocyte adhesion on nanotubular anodized titanium. J Biomed Mater Res A 2009, 88:561-568.
56. Zanetti N.C., Solursh M. Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton. J Cell Biol 1984, 99:115-123.
57. Loty S., Forest N., Boulekbache H., Sautier J.M. Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: a morphological study. Biol Cell 1995, 83:149-161.
58. Li W.J., Jiang Y.J., Tuan R.S. Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size. Tissue Eng 2006, 12:1775-1785.
59. Benjamin M., Archer C.W., Ralphs J.R. Cytoskeleton of cartilage cells. Microsc Res Tech 1994, 28:372-377.
60. Kinner B., Spector M. Smooth muscle actin expression by human articular chondrocytes and their contraction of a collagen-glycosaminoglycan matrix in vitro. J Orthop Res 2001, 19:233-241.
61. Sechriest V.F., Miao Y.J., Niyibizi C., Westerhausen-Larson A., Matthew H.W., Evans C.H., et al. GAG-augmented polysaccharide hydrogel: a novel biocompatible and biodegradable material to support chondrogenesis. J Biomed Mater Res 2000, 49:534-541.