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Volumn 79, Issue 10, 1997, Pages 1452-1463

The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; COLLAGEN TYPE 2; RECOMBINANT PROTEIN;

EID: 0030720510     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/00004623-199710000-00002     Document Type: Article
Times cited : (352)

References (47)
  • 1
    • 0022644316 scopus 로고
    • Repair of articular surfaces by allografts of articular and growth-plate cartilage
    • Aston, J. E., and Bentley, G.: Repair of articular surfaces by allografts of articular and growth-plate cartilage. J. Bone and Joint Surg., 68-B(1): 29-35, 1986.
    • (1986) J. Bone and Joint Surg. , vol.68 B , Issue.1 , pp. 29-35
    • Aston, J.E.1    Bentley, G.2
  • 2
    • 0001077621 scopus 로고
    • A study of the repair of articular cartilage and the reaction of normal joints of adult dogs to surgically created defects of articular cartilage, "joint mice" and patellar displacement
    • Bennett, G. A.; Bauer, W.; and Maddock, S. J.: A study of the repair of articular cartilage and the reaction of normal joints of adult dogs to surgically created defects of articular cartilage, "joint mice" and patellar displacement. Am. J. Pathol., 8: 499-523, 1932.
    • (1932) Am. J. Pathol. , vol.8 , pp. 499-523
    • Bennett, G.A.1    Bauer, W.2    Maddock, S.J.3
  • 3
    • 0015216140 scopus 로고
    • Homotransplantation of isolated epiphyseal and articular cartilage chondrocytes into joint surfaces of rabbits
    • Bentley, G., and Greer, R. B., III: Homotransplantation of isolated epiphyseal and articular cartilage chondrocytes into joint surfaces of rabbits. Nature, 230: 385-388, 1971.
    • (1971) Nature , vol.230 , pp. 385-388
    • Bentley, G.1    Greer III, R.B.2
  • 4
    • 0029993566 scopus 로고    scopus 로고
    • Rabbit articular cartilage defects treated with autologous cultured chondrocytes
    • Brittberg, M.; Nilsson, A.; Lindahl, A.; Ohlsson, C.; and Peterson, L.: Rabbit articular cartilage defects treated with autologous cultured chondrocytes. Clin. Orthop., 326: 270-283, 1996.
    • (1996) Clin. Orthop. , vol.326 , pp. 270-283
    • Brittberg, M.1    Nilsson, A.2    Lindahl, A.3    Ohlsson, C.4    Peterson, L.5
  • 5
    • 0028031550 scopus 로고
    • Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
    • Brittberg, M.; Lindahl, A.; Nilsson, A.; Ohlsson, C.; Isaksson, O.; and Peterson, L.: Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. New England J. Med., 31: 889-895, 1994.
    • (1994) New England J. Med. , vol.31 , pp. 889-895
    • Brittberg, M.1    Lindahl, A.2    Nilsson, A.3    Ohlsson, C.4    Isaksson, O.5    Peterson, L.6
  • 6
    • 0000061658 scopus 로고
    • Proliferation, regeneration, and repair of articular cartilage of immature animals
    • April
    • Calandruccio, R. A., and Gilmer, W. S., Jr.: Proliferation, regeneration, and repair of articular cartilage of immature animals. J. Bone and Joint Surg., 44-A: 431-455, April 1962.
    • (1962) J. Bone and Joint Surg. , vol.44 A , pp. 431-455
    • Calandruccio, R.A.1    Gilmer Jr., W.S.2
  • 7
    • 0003259319 scopus 로고
    • Reactions of rabbit patellar cartilage following operative defects
    • Carlson, H.: Reactions of rabbit patellar cartilage following operative defects. Acta Orthop. Scandinavica, Supplementum 28, 1957.
    • (1957) Acta Orthop. Scandinavica , Issue.28 SUPPL.
    • Carlson, H.1
  • 8
    • 0025672641 scopus 로고
    • Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone
    • Celeste, A. J.; Ianaazzi, J. A.; Taylor, R. C.; Hewick, R. M.; Rosen, V.; Wang, E. A.; and Wozney, J. M.; Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc. Nat. Acad. Sci., 87: 9843-9847, 1990.
    • (1990) Proc. Nat. Acad. Sci. , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Ianaazzi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5    Wang, E.A.6    Wozney, J.M.7
  • 9
    • 0028126646 scopus 로고
    • Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development
    • Chang, S. C.; Hoang, B.; Thomas, J. T.; Vukicevic, S.; Luyten, F. P.; Ryba, N. J.; Kozak, C. A.; Reddi, A. H.; and Moos, M., Jr.: Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development. J. Biol. Chem., 269: 28227-28234, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28227-28234
    • Chang, S.C.1    Hoang, B.2    Thomas, J.T.3    Vukicevic, S.4    Luyten, F.P.5    Ryba, N.J.6    Kozak, C.A.7    Reddi, A.H.8    Moos Jr., M.9
  • 10
    • 0014253940 scopus 로고
    • Homotransplantation of articular cartilage and isolated chondrocytes. An experimental study in rabbits
    • Chesterman, P. J., and Smith, A. U.: Homotransplantation of articular cartilage and isolated chondrocytes. An experimental study in rabbits. J. Bone and Joint Surg., 50-B(1): 184-197, 1968.
    • (1968) J. Bone and Joint Surg. , vol.50 B , Issue.1 , pp. 184-197
    • Chesterman, P.J.1    Smith, A.U.2
  • 11
    • 0015263120 scopus 로고
    • The repair of large osteochondral defects. An experimental study in horses
    • Convery, F. R.; Akeson, W. H.; and Keown, G. H.: The repair of large osteochondral defects. An experimental study in horses. Clin. Orthop., 82: 253-262, 1972.
    • (1972) Clin. Orthop. , vol.82 , pp. 253-262
    • Convery, F.R.1    Akeson, W.H.2    Keown, G.H.3
  • 12
    • 0026810969 scopus 로고
    • Rib perichondrial autografts in full-thickness articular cartilage defects in rabbits
    • Coutts, R. D.; Woo, S. L.; Amiel, D.; von Schroeder, H. P.; and Kwan, M. K.: Rib perichondrial autografts in full-thickness articular cartilage defects in rabbits. Clin. Orthop., 275: 263-273, 1992.
    • (1992) Clin. Orthop. , vol.275 , pp. 263-273
    • Coutts, R.D.1    Woo, S.L.2    Amiel, D.3    Von Schroeder, H.P.4    Kwan, M.K.5
  • 13
    • 0026026775 scopus 로고
    • Demineralized allogeneic bone matrix for cartilage repair
    • Dahlberg, L., and Kreicbergs, A.: Demineralized allogeneic bone matrix for cartilage repair. J. Orthop. Res., 9: 11-19, 1991.
    • (1991) J. Orthop. Res. , vol.9 , pp. 11-19
    • Dahlberg, L.1    Kreicbergs, A.2
  • 14
    • 0013945532 scopus 로고
    • Process of repair of articular cartilage demonstrated by histology and autoradiography with tritiated thymidine
    • DePalma, A. F.; McKeever, C. D.; and Subin, D. K.: Process of repair of articular cartilage demonstrated by histology and autoradiography with tritiated thymidine. Clin. Orthop., 48: 229-242, 1966.
    • (1966) Clin. Orthop. , vol.48 , pp. 229-242
    • DePalma, A.F.1    McKeever, C.D.2    Subin, D.K.3
  • 15
    • 0018907293 scopus 로고
    • Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee
    • Jan.
    • Furukawa, T.; Eyre, D. R.; Koide, S.; and Glimcher, M. J.: Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee. J. Bone and Joint Surg., 62-A: 79-89, Jan. 1980.
    • (1980) J. Bone and Joint Surg. , vol.62 A , pp. 79-89
    • Furukawa, T.1    Eyre, D.R.2    Koide, S.3    Glimcher, M.J.4
  • 16
    • 0023274105 scopus 로고
    • Healing of experimentally produced lesions in articular cartilage following chondrocyte transplantation
    • Grande, D. A.; Singh, I. J.; and Pugh, J.: Healing of experimentally produced lesions in articular cartilage following chondrocyte transplantation. Anat. Rec., 218: 142-148, 1987.
    • (1987) Anat. Rec. , vol.218 , pp. 142-148
    • Grande, D.A.1    Singh, I.J.2    Pugh, J.3
  • 18
    • 0029930722 scopus 로고    scopus 로고
    • Repair of partial-thickness defects in articular cartilage: Cell recruitment from the synovial membrane
    • May
    • Hunziker, E. B., and Rosenberg, L. C.: Repair of partial-thickness defects in articular cartilage: cell recruitment from the synovial membrane. J. Bone and Joint Surg., 78-A: 721-733, May 1996.
    • (1996) J. Bone and Joint Surg. , vol.78 A , pp. 721-733
    • Hunziker, E.B.1    Rosenberg, L.C.2
  • 19
    • 0025114650 scopus 로고
    • The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2
    • Katagiri, T.; Yamaguchi, A.; Ikeda, T.; Yoshiki, S.; Wozney, J. M.; Rosen, V.; Wang, E. A.; Tanaka, H.; Omura, S.; and Suda, T.: The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem. and Biophys. Res. Commun., 172: 295-299, 1990.
    • (1990) Biochem. and Biophys. Res. Commun. , vol.172 , pp. 295-299
    • Katagiri, T.1    Yamaguchi, A.2    Ikeda, T.3    Yoshiki, S.4    Wozney, J.M.5    Rosen, V.6    Wang, E.A.7    Tanaka, H.8    Omura, S.9    Suda, T.10
  • 20
    • 0028931238 scopus 로고
    • Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-beta receptor
    • Kawabata, M.; Chytil, A.; and Moses, H. L.: Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-beta receptor. J. Biol. Chem., 270: 5625-5630, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5625-5630
    • Kawabata, M.1    Chytil, A.2    Moses, H.L.3
  • 21
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley, D. M.: The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes and Devel., 8: 133-146, 1994.
    • (1994) Genes and Devel. , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 23
    • 0029609694 scopus 로고
    • Cartilage-derived morphogenetic proteins. Key regulators in chondrocyte differentiation?
    • Luyten, F. P.: Cartilage-derived morphogenetic proteins. Key regulators in chondrocyte differentiation? Acta Orthop. Scandinavica, Supplementum 266, pp. 51-54, 1995.
    • (1995) Acta Orthop. Scandinavica , Issue.266 SUPPL. , pp. 51-54
    • Luyten, F.P.1
  • 24
    • 0026709638 scopus 로고
    • Natural bovine osteogenin and recombinant human bone morphogenetic protein-2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures
    • Luyten, F. P.; Yu, Y. M.; Yanagishita, M.; Vukicevic, S.; Hammonds, R. G.; and Reddi, A. H.: Natural bovine osteogenin and recombinant human bone morphogenetic protein-2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures. J. Biol. Chem., 267: 3691-3695, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3691-3695
    • Luyten, F.P.1    Yu, Y.M.2    Yanagishita, M.3    Vukicevic, S.4    Hammonds, R.G.5    Reddi, A.H.6
  • 25
    • 0024991197 scopus 로고
    • Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A)
    • Lyons, K. M.; Pelton, R. M.; and Hogan, B. L.: Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development, 109: 833-844, 1990.
    • (1990) Development , vol.109 , pp. 833-844
    • Lyons, K.M.1    Pelton, R.M.2    Hogan, B.L.3
  • 26
    • 0016333824 scopus 로고
    • The reaction of articular cartilage to injury and osteoarthritis (first of two parts)
    • Mankin, H. J.: The reaction of articular cartilage to injury and osteoarthritis (first of two parts). New England J. Med., 291: 1285-1292, 1974.
    • (1974) New England J. Med. , vol.291 , pp. 1285-1292
    • Mankin, H.J.1
  • 27
    • 0343371851 scopus 로고    scopus 로고
    • Evidence for insufficient chondrocytic differentiation during repair of full-thickness defects of articular cartilage
    • Metsaranta, M.; Kujala, U. M.; Pelliniemi, L.; Osterman, H.; Aho, H.; and Vuorio, E.: Evidence for insufficient chondrocytic differentiation during repair of full-thickness defects of articular cartilage. Matrix Biol., 15: 39-47, 1996.
    • (1996) Matrix Biol. , vol.15 , pp. 39-47
    • Metsaranta, M.1    Kujala, U.M.2    Pelliniemi, L.3    Osterman, H.4    Aho, H.5    Vuorio, E.6
  • 28
    • 0000088108 scopus 로고
    • Enzymatical digestion for the repair of superficial articular cartilage lesions
    • Mochizuki, Y.; Goldberg, V. M.; and Caplan, A. I.: Enzymatical digestion for the repair of superficial articular cartilage lesions. Trans. Orthop. Res. Soc., 18: 728, 1994.
    • (1994) Trans. Orthop. Res. Soc. , vol.18 , pp. 728
    • Mochizuki, Y.1    Goldberg, V.M.2    Caplan, A.I.3
  • 29
    • 0025914757 scopus 로고
    • Experimental studies on repair of large osteochondral defects at a high weight bearing area of the knee joint: A tissue engineering study
    • Mow, V. C.; Ratcliffe, A.; Rosenwasser, M. P.; and Buckwalter, J. A.: Experimental studies on repair of large osteochondral defects at a high weight bearing area of the knee joint: a tissue engineering study. J. Biomech. Eng., 113: 198-207, 1991.
    • (1991) J. Biomech. Eng. , vol.113 , pp. 198-207
    • Mow, V.C.1    Ratcliffe, A.2    Rosenwasser, M.P.3    Buckwalter, J.A.4
  • 30
    • 0029134685 scopus 로고
    • Effect of tissue culture storage on the in vivo survival of canine osteochondral allografts
    • Oates, K. M.; Chen, A. C.; Young, E. P.; Kwan, M. K.; Amiel, D.; and Convery, F. R.: Effect of tissue culture storage on the in vivo survival of canine osteochondral allografts. J. Orthop. Res., 13: 562-569, 1995.
    • (1995) J. Orthop. Res. , vol.13 , pp. 562-569
    • Oates, K.M.1    Chen, A.C.2    Young, E.P.3    Kwan, M.K.4    Amiel, D.5    Convery, F.R.6
  • 31
    • 84940626210 scopus 로고
    • A semiquantitative scale for histologic grading of articular cartilage repair
    • Pineda, S.; Pollack, A.; Stevenson, S.; Goldberg, V.; and Caplan, A.: A semiquantitative scale for histologic grading of articular cartilage repair. Acta Anat., 143: 335-340, 1992.
    • (1992) Acta Anat. , vol.143 , pp. 335-340
    • Pineda, S.1    Pollack, A.2    Stevenson, S.3    Goldberg, V.4    Caplan, A.5
  • 32
    • 0029360563 scopus 로고
    • Integrative repair of articular cartilage in vitro: Adhesive strength of the interface region
    • Reindel, E. S.; Ayroso, A. M.; Chen, A. C.; Chun, D. M.; Schinagl, R. M.; and Sah, R. L.: Integrative repair of articular cartilage in vitro: adhesive strength of the interface region. J. Orthop. Res., 13: 751-760, 1995.
    • (1995) J. Orthop. Res. , vol.13 , pp. 751-760
    • Reindel, E.S.1    Ayroso, A.M.2    Chen, A.C.3    Chun, D.M.4    Schinagl, R.M.5    Sah, R.L.6
  • 33
    • 0024779690 scopus 로고
    • Purification and molecular cloning of a novel group of BMPs and localization of BMP mRNA in developing bone
    • Rosen, V.; Wozney, J. M.; Wang, E. A.; Cordes, P.; Celeste, A.; McQuaid, D.; and Kurtzberg, L.: Purification and molecular cloning of a novel group of BMPs and localization of BMP mRNA in developing bone. Connect. Tissue Res., 20: 313-319, 1989.
    • (1989) Connect. Tissue Res. , vol.20 , pp. 313-319
    • Rosen, V.1    Wozney, J.M.2    Wang, E.A.3    Cordes, P.4    Celeste, A.5    McQuaid, D.6    Kurtzberg, L.7
  • 34
    • 0030497893 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 maintains the articular chondrocyte phenotype in long-term culture
    • Sailor, L. Z.; Hewick, R. M.; and Morris, E. A.: Recombinant human bone morphogenetic protein-2 maintains the articular chondrocyte phenotype in long-term culture. J. Orthop. Res., 14: 937-945, 1996.
    • (1996) J. Orthop. Res. , vol.14 , pp. 937-945
    • Sailor, L.Z.1    Hewick, R.M.2    Morris, E.A.3
  • 35
    • 0021337483 scopus 로고
    • Bone morphogenetic protein-induced cartilage development in tissue culture
    • Sato, K., and Urist, M. R.: Bone morphogenetic protein-induced cartilage development in tissue culture. Clin. Orthop., 183: 180-187, 1984.
    • (1984) Clin. Orthop. , vol.183 , pp. 180-187
    • Sato, K.1    Urist, M.R.2
  • 36
    • 0001332232 scopus 로고
    • The regeneration of hyaline cartilage in joints. An experimental study
    • Shands, A. R., Jr.: The regeneration of hyaline cartilage in joints. An experimental study. Arch. Surg., 22: 137-178, 1931.
    • (1931) Arch. Surg. , vol.22 , pp. 137-178
    • Shands Jr., A.R.1
  • 37
    • 0027288061 scopus 로고
    • Cell origin and differentiation in the repair of full-thickness defects of articular cartilage
    • April
    • Shapiro, F.; Koide, S.; and Glimcher, M. J.: Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J. Bone and Joint Surg., 75-A: 532-553, April 1993.
    • (1993) J. Bone and Joint Surg. , vol.75 A , pp. 532-553
    • Shapiro, F.1    Koide, S.2    Glimcher, M.J.3
  • 38
    • 13344270377 scopus 로고    scopus 로고
    • Healing of chondral and osteochondral defects in a canine model: The role of cultured chondrocytes in regeneration of articular cartilage
    • Shortkroff, S.; Barone, L.; Hsu, H. P.; Wrenn, C.; Gagne, T.; Chi, T.; Breinan, H.; Minas, T.; Sledge, C. B.; Tubo, R.; and Spector, M.: Healing of chondral and osteochondral defects in a canine model: the role of cultured chondrocytes in regeneration of articular cartilage. Biomaterials, 17: 147-154, 1996.
    • (1996) Biomaterials , vol.17 , pp. 147-154
    • Shortkroff, S.1    Barone, L.2    Hsu, H.P.3    Wrenn, C.4    Gagne, T.5    Chi, T.6    Breinan, H.7    Minas, T.8    Sledge, C.B.9    Tubo, R.10    Spector, M.11
  • 39
    • 0029041685 scopus 로고
    • Treatment of articular defects with meniscal allografts in a rabbit knee model
    • Sumen, Y.; Ochi, M.; and Ikuta, Y.: Treatment of articular defects with meniscal allografts in a rabbit knee model. Arthroscopy, 11: 185-193, 1995.
    • (1995) Arthroscopy , vol.11 , pp. 185-193
    • Sumen, Y.1    Ochi, M.2    Ikuta, Y.3
  • 40
    • 0029062193 scopus 로고
    • Use of a guanidine extract of demineralized bone in the treatment of osteochondral defects of articular cartilage
    • Tanaka, T.; Fujii, K.; Ohta, M.; Soshi, S.; Kitamura, A.; and Murota, K.: Use of a guanidine extract of demineralized bone in the treatment of osteochondral defects of articular cartilage. J. Orthop. Res., 13: 464-469, 1995.
    • (1995) J. Orthop. Res. , vol.13 , pp. 464-469
    • Tanaka, T.1    Fujii, K.2    Ohta, M.3    Soshi, S.4    Kitamura, A.5    Murota, K.6
  • 41
    • 0026603456 scopus 로고
    • Recombinant human bone morphogenetic protein-2 induces osteoblastic differentiation in W-20-17 stromal cells
    • Theis, R. S.; Bauduy, M.; Ashton, B. A.; Kurtzberg, L.; Wozney, J. M.; and Rosen, V.: Recombinant human bone morphogenetic protein-2 induces osteoblastic differentiation in W-20-17 stromal cells. Endocrinology, 130: 1318-1324, 1992.
    • (1992) Endocrinology , vol.130 , pp. 1318-1324
    • Theis, R.S.1    Bauduy, M.2    Ashton, B.A.3    Kurtzberg, L.4    Wozney, J.M.5    Rosen, V.6
  • 42
    • 0028277696 scopus 로고
    • Joint resurfacing with cartilage grown in situ from cell-polymer structures
    • Vacanti, C. A.; Kim, W.; Schloo, B.; Upton, J.; and Vacanti, J. P.: Joint resurfacing with cartilage grown in situ from cell-polymer structures. Am. J. Sports Med., 22: 485-488, 1994.
    • (1994) Am. J. Sports Med. , vol.22 , pp. 485-488
    • Vacanti, C.A.1    Kim, W.2    Schloo, B.3    Upton, J.4    Vacanti, J.P.5
  • 47
    • 0026757708 scopus 로고
    • The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats
    • June
    • Yasko, A. W.; Lane, J. M.; Fellinger, E. J.; Rosen, V.; Wozney, J. M.; and Wang, E. A.: The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. J. Bone and Joint Surg., 74-A: 659-670, June 1992.
    • (1992) J. Bone and Joint Surg. , vol.74 A , pp. 659-670
    • Yasko, A.W.1    Lane, J.M.2    Fellinger, E.J.3    Rosen, V.4    Wozney, J.M.5    Wang, E.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.