Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

Science

Volumn 347, Issue 6217, 2015, Pages 49-53

  Santanilla, Alexander Buitrago ^a   Regalado, Erik L ^a   Pereira, Tony ^a   Shevlin, Michael ^a   Bateman, Kevin ^a   Campeau, Louis Charles ^a   Schneeweis, Jonathan ^a   Berritt, Simon ^a   Shi, Zhi Cai ^a   Nantermet, Philippe ^a   Liu, Yong ^a   Helmy, Roy ^a   Welch, Christopher J ^a   Vachal, Petr ^a   Davies, Ian W ^a   Cernak, Tim ^a   Dreher, Spencer D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE; ORGANIC SOLVENT; PALLADIUM; VOLATILE AGENT; DRUG; NANOPARTICLE;

AUTOMATION; BIOTECHNOLOGY; COUPLING; DRUG DEVELOPMENT; MASS SPECTROMETRY; MOLECULAR ANALYSIS; PALLADIUM; REACTION KINETICS; ROBOTICS; VOLATILE ORGANIC COMPOUND;

ANALYTIC METHOD; ARTICLE; AUTOMATION; CATALYSIS; CHEMISTRY; CROSS COUPLING REACTION; ELECTRONICS; MASS SPECTROMETRY; NANOANALYSIS; NANOMOLE SCALE; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION OPTIMIZATION; ROOM TEMPERATURE; SCALE UP; SYNTHESIS; BIOTECHNOLOGY; HIGH THROUGHPUT SCREENING; NANOTECHNOLOGY; PROCEDURES; ROBOTICS;

BIOTECHNOLOGY; CATALYSIS; HIGH-THROUGHPUT SCREENING ASSAYS; MASS SPECTROMETRY; NANOPARTICLES; NANOTECHNOLOGY; PALLADIUM; PHARMACEUTICAL PREPARATIONS; ROBOTICS;

EID: 84922480032     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1259203     Document Type: Article

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