High-throughput purification platform in support of drug discovery

ACS Combinatorial Science

Volumn 14, Issue 1, 2012, Pages 51-59

  Liu, Min ^a   Chen, Kuanchang ^a   Christian, Denny ^a   Fatima, Tazeen ^a   Pissarnitski, Natalya ^a   Streckfuss, Eric ^a   Zhang, Chaowei ^a   Xia, Lei ^a   Borges, Scott ^a   Shi, Zhicai ^a   Vachal, Petr ^a   Tata, James ^a   Athanasopoulos, John ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

High throughput purification; HPLC; instrumentation; LC MS; mass directed; parallel synthesis; preparative chromatography

Indexed keywords

DRUG;

ARTICLE; CHEMISTRY; DRUG DEVELOPMENT; EQUIPMENT DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; INSTRUMENTATION; ISOLATION AND PURIFICATION; METHODOLOGY; QUALITY CONTROL; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DISCOVERY; EQUIPMENT DESIGN; HIGH-THROUGHPUT SCREENING ASSAYS; PHARMACEUTICAL PREPARATIONS; QUALITY CONTROL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862951503     PISSN: 21568952     EISSN: None     Source Type: Journal    
DOI: 10.1021/co200138h     Document Type: Article

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