Cathepsin E promotes pulmonary emphysema via mitochondrial fission

American Journal of Pathology

Volumn 184, Issue 10, 2014, Pages 2730-2741

  Zhang, Xuchen ^a,b   Shan, Peiying ^a   Homer, Robert ^a,b   Zhang, Yi ^a   Petrache, Irina ^c   Mannam, Praveen ^a   Lee, Patty J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CATHEPSIN E; CIGARETTE SMOKE; DYNAMIN RELATED PROTEIN 1; PARKIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; 3-(2,4-DICHLORO-5-METHOXYPHENYL)-2-SULFANYL-4(3H)-QUINAZOLINONE; BENZYLOXYCARBONYL-VALYL-ALANYL-ASPARTIC ACID; CTSE PROTEIN, HUMAN; CTSE PROTEIN, MOUSE; OLIGOPEPTIDE; PASSIVE SMOKING; QUINAZOLINONE DERIVATIVE; SMOKE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; APOPTOSIS; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG EMPHYSEMA; LUNG PARENCHYMA; LUNG VOLUME; MITOCHONDRION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TISSUE SECTION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; GENETICS; HUMAN; LUNG; LUNG LAVAGE; METABOLISM; MITOCHONDRIAL DYNAMICS; PASSIVE SMOKING; PATHOPHYSIOLOGY; SMOKE;

ANIMALS; APOPTOSIS; BRONCHOALVEOLAR LAVAGE; CATHEPSIN E; HUMANS; LUNG; MICE; MICE, INBRED C57BL; MITOCHONDRIAL DYNAMICS; OLIGOPEPTIDES; PULMONARY EMPHYSEMA; QUINAZOLINONES; SMOKE; TOBACCO SMOKE POLLUTION;

EID: 84922462879     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.06.017     Document Type: Article

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