Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 5, 2015, Pages 749-758

  Roussel, J ^a   Thireau, J ^a   Brenner, C ^b   Saint, N ^a   Scheuermann, V ^a   Lacampagne, A ^a   Le Guennec, J Y ^a   Fauconnier, J ^a  

^a UNIV MONTPELLIER   (France)

^b Universite Paris Sud   (France)

Author keywords

ANT; Long chain acyl carnitine; Reactive oxygen species; RyR2

Indexed keywords

ACETYLCYSTEINE; ADENINE NUCLEOTIDE TRANSLOCASE; BONGKREKIC ACID; CALCIUM; FK 506 BINDING PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL PROTEIN; PALMITOYL COENZYME A; PALMITOYLCARNITINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RYANODINE RECEPTOR 2; CARRIER PROTEIN; NITRIC OXIDE; RYANODINE RECEPTOR; SCAVENGER; TACROLIMUS BINDING PROTEIN 1B;

ANIMAL CELL; ARTICLE; CELL ISOLATION; DISSOCIATION; ELECTROCARDIOGRAM; ENZYME ACTIVITY; ENZYME REGULATION; FATTY ACID METABOLISM; HEART MUSCLE CELL; HEART REPOLARIZATION; HEART VENTRICLE EXTRASYSTOLE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION; PR INTERVAL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; QT INTERVAL; SARCOPLASMIC RETICULUM; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; HEART MITOCHONDRION; IMMUNOBLOTTING; MALE; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

MUS;

ACETYLCYSTEINE; ANIMALS; BONGKREKIC ACID; CALCIUM; CELLS, CULTURED; FREE RADICAL SCAVENGERS; IMMUNOBLOTTING; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MITOCHONDRIA, HEART; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCYTES, CARDIAC; NITRIC OXIDE; OXIDATION-REDUCTION; PALMITOYLCARNITINE; REACTIVE OXYGEN SPECIES; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; TACROLIMUS BINDING PROTEINS;

EID: 84922365747     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.01.011     Document Type: Article

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