메뉴 건너뛰기




Volumn 290, Issue 6, 2015, Pages 3455-3467

The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

EID: 84922340030     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.605253     Document Type: Article
Times cited : (182)

References (58)
  • 7
    • 67949097489 scopus 로고    scopus 로고
    • Exosomes: Vesicular carriers for intercellular communication
    • Simons, M., and Raposo, G. (2009) Exosomes: vesicular carriers for intercellular communication. Curr. Opin. Cell Biol.. 21, 575-581
    • (2009) Curr. Opin. Cell Biol.. , vol.21 , pp. 575-581
    • Simons, M.1    Raposo, G.2
  • 8
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., and Lötvall, J. O. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nature Cell Biology. 9, 654-659
    • (2007) Nature Cell Biology. , vol.9 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5    Lötvall, J.O.6
  • 9
    • 84870599244 scopus 로고    scopus 로고
    • Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
    • Bellingham, S. A., Coleman, B. M., and Hill, A. F. (2012) Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Nucleic Acids Res. 40, 10937-10949
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10937-10949
    • Bellingham, S.A.1    Coleman, B.M.2    Hill, A.F.3
  • 10
    • 84868149990 scopus 로고    scopus 로고
    • Prioninfected cells regulate the release of exosomes with distinct ultrastructural features
    • Coleman, B. M., Hanssen, E., Lawson, V. A., and Hill, A. F. (2012) Prioninfected cells regulate the release of exosomes with distinct ultrastructural features. Faseb J. 26, 4160-4173
    • (2012) Faseb J. , vol.26 , pp. 4160-4173
    • Coleman, B.M.1    Hanssen, E.2    Lawson, V.A.3    Hill, A.F.4
  • 11
    • 0026094139 scopus 로고
    • Shedding of vesicular material from the cell surface of eukaryotic cells: Different cellular phenomena
    • Beaudoin, A. R., and Grondin, G. (1991) Shedding of vesicular material from the cell surface of eukaryotic cells: different cellular phenomena. Biochim. Biophys. Acta 13, 203-219
    • (1991) Biochim. Biophys. Acta , vol.13 , pp. 203-219
    • Beaudoin, A.R.1    Grondin, G.2
  • 12
  • 13
    • 33947709328 scopus 로고    scopus 로고
    • Packaging of prions into exosomes is associated with a novel pathway of PrP processing
    • Vella, L. J., Sharples, R. A., Lawson, V. A., Masters, C. L., Cappai, R., and Hill, A. F. (2007) Packaging of prions into exosomes is associated with a novel pathway of PrP processing. J. Pathol. 211, 582-590
    • (2007) J. Pathol. , vol.211 , pp. 582-590
    • Vella, L.J.1    Sharples, R.A.2    Lawson, V.A.3    Masters, C.L.4    Cappai, R.5    Hill, A.F.6
  • 15
    • 43249087541 scopus 로고    scopus 로고
    • Inhibition of -secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
    • Sharples, R. A., Vella, L. J., Nisbet, R. M., Naylor, R., Perez, K., Barnham, K. J., Masters, C. L., and Hill, A. F. (2008) Inhibition of -secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes. Faseb J. 22, 1469-1478
    • (2008) Faseb J. , vol.22 , pp. 1469-1478
    • Sharples, R.A.1    Vella, L.J.2    Nisbet, R.M.3    Naylor, R.4    Perez, K.5    Barnham, K.J.6    Masters, C.L.7    Hill, A.F.8
  • 17
    • 84856707794 scopus 로고    scopus 로고
    • Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
    • Saman, S., Kim, W., Raya, M., Visnick, Y., Miro, S., Jackson, B., McKee, A. C., Alvarez, V. E., Lee, N. C., and Hall, G. F. (2012) Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J. Biol. Chem. 287, 3842-3849
    • (2012) J. Biol. Chem. , vol.287 , pp. 3842-3849
    • Saman, S.1    Kim, W.2    Raya, M.3    Visnick, Y.4    Miro, S.5    Jackson, B.6    McKee, A.C.7    Alvarez, V.E.8    Lee, N.C.9    Hall, G.F.10
  • 18
    • 35448956015 scopus 로고    scopus 로고
    • Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis
    • Gomes, C., Keller, S., Altevogt, P., and Costa, J. (2007) Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis. Neuroscience Letters 428, 43-46
    • (2007) Neuroscience Letters , vol.428 , pp. 43-46
    • Gomes, C.1    Keller, S.2    Altevogt, P.3    Costa, J.4
  • 20
    • 84866426167 scopus 로고    scopus 로고
    • Exosomes: Vehicles for the transfer of toxic proteins associated with neurodegenerative diseases
    • Bellingham, S. A., Guo, B. B., Coleman, B. M., and Hill, A. F. (2012) Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front. Physiol. 3, 124
    • (2012) Front. Physiol. , vol.3 , pp. 124
    • Bellingham, S.A.1    Guo, B.B.2    Coleman, B.M.3    Hill, A.F.4
  • 22
    • 63649086486 scopus 로고    scopus 로고
    • The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
    • Raiborg, C., and Stenmark, H. (2009) The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature 458, 445-452
    • (2009) Nature , vol.458 , pp. 445-452
    • Raiborg, C.1    Stenmark, H.2
  • 23
    • 0345599951 scopus 로고    scopus 로고
    • Lipid raft-associated protein sorting in exosomes
    • de Gassart, A., Geminard, C., Fevrier, B., Raposo, G., and Vidal, M. (2003) Lipid raft-associated protein sorting in exosomes. Blood 102, 4336-4344
    • (2003) Blood , vol.102 , pp. 4336-4344
    • De Gassart, A.1    Geminard, C.2    Fevrier, B.3    Raposo, G.4    Vidal, M.5
  • 24
    • 34250325547 scopus 로고    scopus 로고
    • Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes
    • Fang, Y., Wu, N., Gan, X., Yan, W., Morrell, J. C., and Gould, S. J. (2007) Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes. PLoS Biology 5, 1267-1283
    • (2007) PLoS Biology , vol.5 , pp. 1267-1283
    • Fang, Y.1    Wu, N.2    Gan, X.3    Yan, W.4    Morrell, J.C.5    Gould, S.J.6
  • 27
    • 77952920881 scopus 로고    scopus 로고
    • Secretory mechanisms and intercellular transfer of microRNAs in living cells
    • Kosaka, N., Iguchi, H., Yoshioka, Y., Takeshita, F., Matsuki, Y., and Ochiya, T. (2010) Secretory mechanisms and intercellular transfer of microRNAs in living cells. J. Biol. Chem. 285, 17442-17452
    • (2010) J. Biol. Chem. , vol.285 , pp. 17442-17452
    • Kosaka, N.1    Iguchi, H.2    Yoshioka, Y.3    Takeshita, F.4    Matsuki, Y.5    Ochiya, T.6
  • 28
    • 84859499570 scopus 로고    scopus 로고
    • Sphingolipidmodulated exosome secretion promotes clearance of amyloid-beta by microglia
    • Yuyama, K., Sun, H., Mitsutake, S., and Igarashi, Y. (2012) Sphingolipidmodulated exosome secretion promotes clearance of amyloid-beta by microglia. J. Biol. Chem. 287, 10977-10989
    • (2012) J. Biol. Chem. , vol.287 , pp. 10977-10989
    • Yuyama, K.1    Sun, H.2    Mitsutake, S.3    Igarashi, Y.4
  • 29
    • 78649802553 scopus 로고    scopus 로고
    • Mammalian neutral sphingomyelinases: Regulation and roles in cell signaling responses
    • Wu, B. X., Clarke, C. J., and Hannun, Y. A. (2010) Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses. Neu-romolecular Medicine 12, 320-330
    • (2010) Neu-romolecular Medicine , vol.12 , pp. 320-330
    • Wu, B.X.1    Clarke, C.J.2    Hannun, Y.A.3
  • 30
    • 0034705097 scopus 로고    scopus 로고
    • Cloning and characterization of the mammalian brain-specific, Mg2-dependent neutral sphingomyelinase
    • Hofmann, K., Tomiuk, S., Wolff, G., and Stoffel, W. (2000) Cloning and characterization of the mammalian brain-specific, Mg2-dependent neutral sphingomyelinase. Proc. Natl. Acad. Sci. U.S.A. 97, 5895-5900
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 5895-5900
    • Hofmann, K.1    Tomiuk, S.2    Wolff, G.3    Stoffel, W.4
  • 31
    • 33744953581 scopus 로고    scopus 로고
    • Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein
    • Krut, O., Wiegmann, K., Kashkar, H., Yazdanpanah, B., and Krönke, M. (2006) Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein. J. Biol. Chem. 281, 13784-13793
    • (2006) J. Biol. Chem. , vol.281 , pp. 13784-13793
    • Krut, O.1    Wiegmann, K.2    Kashkar, H.3    Yazdanpanah, B.4    Krönke, M.5
  • 32
    • 77952937382 scopus 로고    scopus 로고
    • Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5
    • Wu, B. X., Rajagopalan, V., Roddy, P. L., Clarke, C. J., and Hannun, Y. A. (2010) Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5. J. Biol. Chem. 285, 17993-18002
    • (2010) J. Biol. Chem. , vol.285 , pp. 17993-18002
    • Wu, B.X.1    Rajagopalan, V.2    Roddy, P.L.3    Clarke, C.J.4    Hannun, Y.A.5
  • 34
    • 59449087527 scopus 로고    scopus 로고
    • Regulation of prion gene expression by transcription factors sp1 and metal transcription factor-1
    • Bellingham, S. A., Coleman, L. A., Masters, C. L., Camakaris, J., and Hill, A. F. (2009) Regulation of Prion Gene Expression by Transcription Factors SP1 and Metal Transcription Factor-1. J. Biol. Chem. 284, 1291-1301
    • (2009) J. Biol. Chem. , vol.284 , pp. 1291-1301
    • Bellingham, S.A.1    Coleman, L.A.2    Masters, C.L.3    Camakaris, J.4    Hill, A.F.5
  • 35
    • 33644811612 scopus 로고
    • A new and rapid colorimetric determination of acetylcholinesterase activity
    • Ellman, G. L., Courtney, K. D., Andres, V., and Featherstone, R. M. (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7, 88-95
    • (1961) Biochem. Pharmacol. , vol.7 , pp. 88-95
    • Ellman, G.L.1    Courtney, K.D.2    Andres, V.3    Featherstone, R.M.4
  • 36
    • 50949128891 scopus 로고    scopus 로고
    • Discrimination between exosomes and HIV-1: Purification of both vesicles from cell-free supernatants
    • Cantin, R., Diou, J., Bélanger, D., Tremblay, A. M., and Gilbert, C. (2008) Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants. J. Immunol. Methods 338, 21-30
    • (2008) J. Immunol. Methods , vol.338 , pp. 21-30
    • Cantin, R.1    Diou, J.2    Bélanger, D.3    Tremblay, A.M.4    Gilbert, C.5
  • 37
    • 0032055112 scopus 로고    scopus 로고
    • Decayaccelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during in vitro maturation of reticulocytes
    • Rabesandratana, H., Toutant, J. P., Reggio, H., and Vidal, M. (1998) Decayaccelerating factor (CD55) and membrane inhibitor of reactive lysis (CD59) are released within exosomes during in vitro maturation of reticulocytes. Blood 91, 2573-2580
    • (1998) Blood , vol.91 , pp. 2573-2580
    • Rabesandratana, H.1    Toutant, J.P.2    Reggio, H.3    Vidal, M.4
  • 38
    • 84905485531 scopus 로고    scopus 로고
    • Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine
    • Cheng, L., Sun, X., Scicluna, B. J., Coleman, B. M., and Hill, A. F. (2014) Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine. Kidney Int. 86, 433-444
    • (2014) Kidney Int. , vol.86 , pp. 433-444
    • Cheng, L.1    Sun, X.2    Scicluna, B.J.3    Coleman, B.M.4    Hill, A.F.5
  • 40
    • 84863205849 scopus 로고    scopus 로고
    • NIH Image to ImageJ: 25 years of image analysis
    • Schneider, C. A., Rasband, W. S., and Eliceiri, K. W. (2012) NIH Image to ImageJ: 25 years of image analysis. Nature Methods 9, 671-675
    • (2012) Nature Methods , vol.9 , pp. 671-675
    • Schneider, C.A.1    Rasband, W.S.2    Eliceiri, K.W.3
  • 41
  • 43
  • 45
    • 0033577806 scopus 로고    scopus 로고
    • A role for neutral sphingomyelinase-mediated ceramide production in T cell receptor-induced apoptosis and mitogen-activated protein kinase-mediated signal transduction
    • Tonnetti, L., Verí, M. C., Bonvini, E., and D'Adamio, L. (1999) A role for neutral sphingomyelinase-mediated ceramide production in T cell receptor-induced apoptosis and mitogen-activated protein kinase-mediated signal transduction. J. Exp. Med. 189, 1581-1589
    • (1999) J. Exp. Med. , vol.189 , pp. 1581-1589
    • Tonnetti, L.1    Verí, M.C.2    Bonvini, E.3    D'adamio, L.4
  • 46
    • 57649210164 scopus 로고    scopus 로고
    • Identification of Mg2-dependent neutral sphingomyelinase 1 as a mediator of heat stress-induced ceramide generation and apoptosis
    • Yabu, T., Imamura, S., Yamashita, M., and Okazaki, T. (2008) Identification of Mg2-dependent neutral sphingomyelinase 1 as a mediator of heat stress-induced ceramide generation and apoptosis. J. Biol. Chem. 283, 29971-29982
    • (2008) J. Biol. Chem. , vol.283 , pp. 29971-29982
    • Yabu, T.1    Imamura, S.2    Yamashita, M.3    Okazaki, T.4
  • 47
    • 53349177064 scopus 로고    scopus 로고
    • Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles
    • Alais, S., Simoes, S., Baas, D., Lehmann, S., Raposo, G., Darlix, J. L., and Leblanc, P. (2008) Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol. Cell 100, 603-615
    • (2008) Biol. Cell , vol.100 , pp. 603-615
    • Alais, S.1    Simoes, S.2    Baas, D.3    Lehmann, S.4    Raposo, G.5    Darlix, J.L.6    Leblanc, P.7
  • 49
    • 0031710192 scopus 로고    scopus 로고
    • Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent
    • Choi, S. I., Ju, W. K., Choi, E. K., Kim, J., Lea, H. Z., Carp, R. I., Wisniewski, H. M., and Kim, Y. S. (1998) Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent. Acta Neuropathologica 96, 279-286
    • (1998) Acta Neuropathologica , vol.96 , pp. 279-286
    • Choi, S.I.1    Ju, W.K.2    Choi, E.K.3    Kim, J.4    Lea, H.Z.5    Carp, R.I.6    Wisniewski, H.M.7    Kim, Y.S.8
  • 50
    • 77956556520 scopus 로고    scopus 로고
    • Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease
    • Sisková, Z., Mahad, D. J., Pudney, C., Campbell, G., Cadogan, M., Asuni, A., O'Connor, V., and Perry, V. H. (2010) Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease. Am. J. Pathol. 177, 1411-1421
    • (2010) Am. J. Pathol. , vol.177 , pp. 1411-1421
    • Sisková, Z.1    Mahad, D.J.2    Pudney, C.3    Campbell, G.4    Cadogan, M.5    Asuni, A.6    O'connor, V.7    Perry, V.H.8
  • 53
    • 0034102425 scopus 로고    scopus 로고
    • Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase
    • Tomiuk, S., Zumbansen, M., and Stoffel, W. (2000) Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase. J. Biol. Chem. 275, 5710-5717
    • (2000) J. Biol. Chem. , vol.275 , pp. 5710-5717
    • Tomiuk, S.1    Zumbansen, M.2    Stoffel, W.3
  • 54
    • 77957938907 scopus 로고    scopus 로고
    • Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane
    • Milhas, D., Clarke, C. J., Idkowiak-Baldys, J., Canals, D., and Hannun, Y. A. (2010) Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane. Biochim. Biophys. Acta 1801, 1361-1374
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 1361-1374
    • Milhas, D.1    Clarke, C.J.2    Idkowiak-Baldys, J.3    Canals, D.4    Hannun, Y.A.5
  • 55
    • 2942532249 scopus 로고    scopus 로고
    • Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells
    • Marchesini, N., Osta, W., Bielawski, J., Luberto, C., Obeid, L. M., and Hannun, Y. A. (2004) Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells. J. Biol. Chem. 279, 25101-25111
    • (2004) J. Biol. Chem. , vol.279 , pp. 25101-25111
    • Marchesini, N.1    Osta, W.2    Bielawski, J.3    Luberto, C.4    Obeid, L.M.5    Hannun, Y.A.6
  • 56
    • 0038529730 scopus 로고    scopus 로고
    • Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism
    • Marchesini, N., Luberto, C., and Hannun, Y. A. (2003) Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism. J. Biol. Chem. 278, 13775-13783
    • (2003) J. Biol. Chem. , vol.278 , pp. 13775-13783
    • Marchesini, N.1    Luberto, C.2    Hannun, Y.A.3
  • 57
    • 0033597931 scopus 로고    scopus 로고
    • Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions
    • Naslavsky, N., Shmeeda, H., Friedlander, G., Yanai, A., Futerman, A. H., Barenholz, Y., and Taraboulos, A. (1999) Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions. J. Biol. Chem. 274, 20763-20771
    • (1999) J. Biol. Chem. , vol.274 , pp. 20763-20771
    • Naslavsky, N.1    Shmeeda, H.2    Friedlander, G.3    Yanai, A.4    Futerman, A.H.5    Barenholz, Y.6    Taraboulos, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.