Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase

Journal of Biological Chemistry

Volumn 277, Issue 43, 2002, Pages 41128-41139

  Luberto, Chiara ^a   Hassler, Daniel F ^a   Signorelli, Paola ^a   Okamoto, Yasuo ^b   Sawai, Hirofumi ^c   Boros, Eric ^a,d   Hazen Martin, Debra J ^a   Obeid, Lina M ^a,b   Hannun, Yusuf A ^a,d   Smith, Gary K ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b GLAXOSMITHKLINE   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d OSAKA DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; ENZYME KINETICS; ENZYMES; TUMORS;

MITOCHONDRIAL DYSFUNCTION;

BIOCHEMISTRY;

CASPASE; CASPASE 9; CERAMIDE; CYTOCHROME C; ENZYME INHIBITOR; GLUTATHIONE; GW 4869; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAGNESIUM; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; TRYPAN BLUE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CONTROLLED STUDY; DOSE RESPONSE; ELECTROPHORETIC MOBILITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOBLOTTING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ANILINE COMPOUNDS; ANIMALS; BENZYLIDENE COMPOUNDS; CELL DEATH; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON; NF-KAPPA B; RATS; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 18644379261     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206747200     Document Type: Article

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