-
1
-
-
0027416347
-
Thyroid hormone receptors: Multiple forms, multiple possibilities
-
Lazar MA. Thyroid hormone receptors: multiple forms, multiple possibilities. Endocrinol Rev. 1993;14:184–193.
-
(1993)
Endocrinol Rev
, vol.14
, pp. 184-193
-
-
Lazar, M.A.1
-
2
-
-
84875309220
-
Thyroid hormone receptors in health and disease
-
Boelen A, Kwakkel J, Filers E. Thyroid hormone receptors in health and disease. Minerva Endocrinol. 2012;37:291–304.
-
(2012)
Minerva Endocrinol
, vol.37
, pp. 291-304
-
-
Boelen, A.1
Kwakkel, J.2
Filers, E.3
-
3
-
-
77954990538
-
Structure of a thyroid hormone receptor DNAbinding domain homodimer bound to an inverted palindromeDNA response element
-
Chen Y, Young MA. Structure of a thyroid hormone receptor DNAbinding domain homodimer bound to an inverted palindromeDNA response element. Mol Endocrinol. 2010;24:1650–1664.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1650-1664
-
-
Chen, Y.1
Young, M.A.2
-
4
-
-
0028094947
-
Thyroid hormone receptor monomer, homodimer, and heterodimer (With retinoid-X receptor) contact different nucleotide sequences in thyroid hormone response elements
-
Ikeda M, Myungchull R, Chin WW. Thyroid hormone receptor monomer, homodimer, and heterodimer (with retinoid-X receptor) contact different nucleotide sequences in thyroid hormone response elements. Endocrinology. 1994;135:1628–1638.
-
(1994)
Endocrinology
, vol.135
, pp. 1628-1638
-
-
Ikeda, M.1
Myungchull, R.2
Chin, W.W.3
-
5
-
-
0025936209
-
Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor
-
Lazar MA, Berrodin TJ, Harding HP. Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor. Mol Cell Biol. 1991;11:5005–5015.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5005-5015
-
-
Lazar, M.A.1
Berrodin, T.J.2
Harding, H.P.3
-
6
-
-
0028262261
-
Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement
-
Williams GR, Zavacki AM, Harney JW, Brent GA. Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement. Endocrinology. 1994;134:1888–1896.
-
(1994)
Endocrinology
, vol.134
, pp. 1888-1896
-
-
Williams, G.R.1
Zavacki, A.M.2
Harney, J.W.3
Brent, G.A.4
-
7
-
-
0029053917
-
Thyroid hormone receptor homodimers can function as ligand-sensitive repressors
-
Piedrafita FJ, Bindik I, Ortiz MA, Pfahl M. Thyroid hormone receptor homodimers can function as ligand-sensitive repressors. Mol Endocrinol. 1995;9:563–578.
-
(1995)
Mol Endocrinol
, vol.9
, pp. 563-578
-
-
Piedrafita, F.J.1
Bindik, I.2
Ortiz, M.A.3
Pfahl, M.4
-
8
-
-
0026689245
-
Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements
-
Brent GA, Williams GR, Harney JW, et al. Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements. Mol Endocrinol. 1992;6:502–514.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 502-514
-
-
Brent, G.A.1
Williams, G.R.2
Harney, J.W.3
-
9
-
-
0026748811
-
Thyroid hormone alters in vitro DNA binding of monomers and dimers of thyroid hormone receptors
-
Ribeiro RC, Kushner PJ, Apriletti JW, West BL, Baxter JD. Thyroid hormone alters in vitro DNA binding of monomers and dimers of thyroid hormone receptors. Mol Endocrinol. 1992;6:1142–1152.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 1142-1152
-
-
Ribeiro, R.C.1
Kushner, P.J.2
Apriletti, J.W.3
West, B.L.4
Baxter, J.D.5
-
10
-
-
0028874316
-
Similar ligand-induced conformational changes of thyroid hormone receptors regulate homo- and heterodimeric functions
-
Bendik I, Pfahl M. Similar ligand-induced conformational changes of thyroid hormone receptors regulate homo- and heterodimeric functions. J Biol Chem. 1995;270:3107–3114.
-
(1995)
J Biol Chem
, vol.270
, pp. 3107-3114
-
-
Bendik, I.1
Pfahl, M.2
-
11
-
-
77958615259
-
Dissecting the relation between a nuclear receptor and GATA: Binding affinity studies of thyroid hormone receptor and GATA2 on TSHb promoter
-
Figueira ACM, Polikarpov I, Veprintsev D, Santos GM. Dissecting the relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHb promoter. PLoS One. 2010;5:e12628.
-
(2010)
Plos One
, vol.5
-
-
Figueira, A.1
Polikarpov, I.2
Veprintsev, D.3
Santos, G.M.4
-
12
-
-
79958286397
-
Molecular basis for genespecific transactivation by nuclear receptors
-
Agaard MM, Siersbaek R, Mandrup S. Molecular basis for genespecific transactivation by nuclear receptors. Biochim Biophys Acta. 2011;1812:824–835.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 824-835
-
-
Agaard, M.M.1
Siersbaek, R.2
Mandrup, S.3
-
13
-
-
3242784885
-
Mechanism of the nuclear receptor molecular switch
-
Nagy L, Schwabe JWR. Mechanism of the nuclear receptor molecular switch. Trends Biochem Sci. 2004;29:317–324.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 317-324
-
-
Nagy, L.1
Schwabe, J.2
-
14
-
-
79952103416
-
Negative regulation by nudoiclear receptors: A plethora of mechanisms
-
Santos GM, Fairall L, Schwabe JWR. Negative regulation by nudoiclear receptors: a plethora of mechanisms. Trends Endocrinol Metab. 2011;22:87–93.
-
(2011)
Trends Endocrinol Metab
, vol.22
, pp. 87-93
-
-
Santos, G.M.1
Fairall, L.2
Schwabe, J.3
-
15
-
-
78650304704
-
Mechanisms and significance of nuclear receptor auto- and cross-regulation
-
Bagamasbad P, Denver RJ. Mechanisms and significance of nuclear receptor auto- and cross-regulation. Gen Comp Endocrinol. 2011; 170:3–17.
-
(2011)
Gen Comp Endocrinol
, vol.170
, pp. 3-17
-
-
Bagamasbad, P.1
Denver, R.J.2
-
16
-
-
77951901129
-
Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics
-
Huang P, Chandra V, Rastinejad F. Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annu Rev Physiol. 2010;72:247–272.
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 247-272
-
-
Huang, P.1
Chandra, V.2
Rastinejad, F.3
-
18
-
-
56749130032
-
Structure of the intact PPAR-_-RXR-nuclear receptor complex on DNA
-
Chandra V, Huang P, Hamuro Y, et al. Structure of the intact PPAR-_-RXR-nuclear receptor complex on DNA. Nature. 2008; 456:350–356.
-
(2008)
Nature
, vol.456
, pp. 350-356
-
-
Chandra, V.1
Huang, P.2
Hamuro, Y.3
-
19
-
-
84875363845
-
Multidomain integration in the structure of the HNF-4_ nuclear receptor complex
-
Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4_ nuclear receptor complex. Nature. 2013;495:394–398.
-
(2013)
Nature
, vol.495
, pp. 394-398
-
-
Chandra, V.1
Huang, P.2
Potluri, N.3
Wu, D.4
Kim, Y.5
Rastinejad, F.6
-
20
-
-
84895886993
-
Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA
-
Lou X, Toresson G, Benod C, et al. Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA. Nat Struct Mol Biol. 2014;21:277–281.
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 277-281
-
-
Lou, X.1
Toresson, G.2
Benod, C.3
-
21
-
-
0034058382
-
Differential mechanisms of nuclear receptor regulation by receptor-associated coactivator 3
-
Leo C, Li H, Chen, JD. Differential mechanisms of nuclear receptor regulation by receptor-associated coactivator 3. J. Biol. Chem. 2000;275:5976–5982.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 5976-5982
-
-
Leo, C.1
Li, H.2
Chen, J.D.3
-
22
-
-
0032213219
-
Structure and specificity of nuclear receptor-coactivator interactions
-
Darimont BD, Wagner RL, Apriletti JW, et al. Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev. 1998;12:3343–3356.
-
(1998)
Genes Dev
, vol.12
, pp. 3343-3356
-
-
Darimont, B.D.1
Wagner, R.L.2
Apriletti, J.W.3
-
23
-
-
78751513652
-
Nuclear receptors coactivators: Structural and functional biochemistry
-
Bulynko YA, O’Malley BW. Nuclear receptors coactivators: structural and functional biochemistry. Biochemistry. 2011;50:313–328.
-
(2011)
Biochemistry
, vol.50
, pp. 313-328
-
-
Bulynko, Y.A.1
O’Malley, B.W.2
-
24
-
-
0036132913
-
Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors
-
Ko L, Cardona GR, Henrion-Caude A, Chin WW. Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors. Mol Cell Biol. 2002;22:357–369.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 357-369
-
-
Ko, L.1
Cardona, G.R.2
Henrion-Caude, A.3
Chin, W.W.4
-
25
-
-
78049278719
-
Retinoid X receptors: Common heterodimerization partners with distinct functions
-
Lefebvre P, Benomar Y, Staels B. Retinoid X receptors: common heterodimerization partners with distinct functions. Trends Endocrinol Metab. 2010;21:676–683.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 676-683
-
-
Lefebvre, P.1
Benomar, Y.2
Staels, B.3
-
26
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors
-
Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM. Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors. Nature. 1992;358:771–774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
-
27
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell. 1995;83:841–850.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
28
-
-
15444378492
-
Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties
-
Lee S, Privalsky ML. Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties. Mol Endocrinol. 2005;4:863–878.
-
(2005)
Mol Endocrinol
, vol.4
, pp. 863-878
-
-
Lee, S.1
Privalsky, M.L.2
-
29
-
-
14844292633
-
A method for efficient production of recombinant thyroid hormone receptors reveals that receptor homodimer-DNA binding is enhanced by the coactivator TIF 2
-
Diallo EM, Thompson DL, Koenig RJ. A method for efficient production of recombinant thyroid hormone receptors reveals that receptor homodimer-DNA binding is enhanced by the coactivator TIF 2. Protein Express Purif. 2005;40:292–298.
-
(2005)
Protein Express Purif
, vol.40
, pp. 292-298
-
-
Diallo, E.M.1
Thompson, D.L.2
Koenig, R.J.3
-
30
-
-
0029002298
-
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
-
Forman BM, Umesono K, Chen J, Evans RM. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell. 1995;81:541–550.
-
(1995)
Cell
, vol.81
, pp. 541-550
-
-
Forman, B.M.1
Umesono, K.2
Chen, J.3
Evans, R.M.4
-
31
-
-
84859982562
-
Structural basis for negative cooperativity within agonist-bound TR:RXR heterodimers
-
Putcha BDK, Wright E, Brunzelle JS, Fernandez EJ. Structural basis for negative cooperativity within agonist-bound TR:RXR heterodimers. Proc Natl Acad Sci USA. 2012;109:6084–6087.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 6084-6087
-
-
Putcha, B.1
Wright, E.2
Brunzelle, J.S.3
Fernandez, E.J.4
-
32
-
-
0030853945
-
Both thyroid hormone and 9-cis retinoic acid receptors are required to efficiently mediate the effects of thyroid hormone on embryonic development and specific gene regulation in Xenopus laevis
-
Puzianowska-Kuzincka M, Damjanovski S, Shi Y-B. Both thyroid hormone and 9-cis retinoic acid receptors are required to efficiently mediate the effects of thyroid hormone on embryonic development and specific gene regulation in Xenopus laevis. Mol Cell Biol. 1997; 17:4738–4749.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4738-4749
-
-
Puzianowska-Kuzincka, M.1
Damjanovski, S.2
Shi, Y.-B.3
-
33
-
-
69249090970
-
Direct interdomain interactions can mediate allosterism in the thyroid receptor
-
Putcha BDK, Fernandez EJ. Direct interdomain interactions can mediate allosterism in the thyroid receptor. J Biol Chem. 2009;284: 22517–22524.
-
(2009)
J Biol Chem
, vol.284
, pp. 22517-22524
-
-
Putcha, B.1
Fernandez, E.J.2
-
34
-
-
0347356359
-
A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis retinoic acid
-
Castillo AI, Sánchez-Matínez R, Moreno JL, Martínez-Iglesias OA, Palacios D, Aranda A. A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis retinoic acid. Mol Cell Biol. 2004;24:502–513.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 502-513
-
-
Castillo, A.I.1
Sánchez-Matínez, R.2
Moreno, J.L.3
Martínez-Iglesias, O.A.4
Palacios, D.5
Aranda, A.6
-
35
-
-
0036318975
-
Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer
-
Li D, Li T, Wang F, Tian H, Samuels HH. Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer. Mol Cell Biol. 2002;22: 5782–5792.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5782-5792
-
-
Li, D.1
Li, T.2
Wang, F.3
Tian, H.4
Samuels, H.H.5
-
36
-
-
1542379985
-
Novel roles of retinoid X receptor (RXR) and RXR ligand in dynamically modulating the activity of the thyroid hormone receptor/RXR heterodimer
-
Li D, Yamada T, Wang F, Vulin AI, Samuels HH. Novel roles of retinoid X receptor (RXR) and RXR ligand in dynamically modulating the activity of the thyroid hormone receptor/RXR heterodimer. J Biol Chem. 2004;279:7427–7437.
-
(2004)
J Biol Chem
, vol.279
, pp. 7427-7437
-
-
Li, D.1
Yamada, T.2
Wang, F.3
Vulin, A.I.4
Samuels, H.H.5
-
37
-
-
0014007813
-
Determination of molecular weights and fractional ratios of proteins in impure systems by use of gel-filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases
-
Seigel LM, Monty KJ. Determination of molecular weights and fractional ratios of proteins in impure systems by use of gel-filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. Biochim Biophys Acta. 1966;112:346–362.
-
(1966)
Biochim Biophys Acta
, vol.112
, pp. 346-362
-
-
Seigel, L.M.1
Monty, K.J.2
-
38
-
-
45849096536
-
Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases
-
Whitmore L, Wallace BA. Protein secondary structure analyses from circular dichroism spectroscopy: methods and reference databases. Biopolymers. 2008;89:392–400.
-
(2008)
Biopolymers
, vol.89
, pp. 392-400
-
-
Whitmore, L.1
Wallace, B.A.2
-
39
-
-
3242877618
-
DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data
-
Whitmore L, Wallace BA. DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data. Nucleic Acids Res. 2004;32:W668–W673.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. W668-W673
-
-
Whitmore, L.1
Wallace, B.A.2
-
40
-
-
37249005205
-
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
-
Niesen FH, Berglund H, Vedadi M. The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability. Nat Protoc. 2007;2:2212–2221.
-
(2007)
Nat Protoc
, vol.2
, pp. 2212-2221
-
-
Niesen, F.H.1
Berglund, H.2
Vedadi, M.3
-
41
-
-
0034009520
-
Size distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling
-
Schuck P. Size distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling. Biophys J. 2000;78:1606–1619.
-
(2000)
Biophys J
, vol.78
, pp. 1606-1619
-
-
Schuck, P.1
-
42
-
-
0141484613
-
PRIMUS—a Windows-PC based system for small-angle scattering data analysis
-
Konarev PV, Volkov VV, Sokolova AV, Koch MHJ, Svergun DI. PRIMUS—a Windows-PC based system for small-angle scattering data analysis. J Appl Cryst. 2003;36:1277–1282.
-
(2003)
J Appl Cryst
, vol.36
, pp. 1277-1282
-
-
Konarev, P.V.1
Volkov, V.V.2
Sokolova, A.V.3
Koch, M.4
Svergun, D.I.5
-
43
-
-
0026910457
-
Determination of the regularization parameter in indirect- transform methods using perceptual criteria
-
Svergun DI. Determination of the regularization parameter in indirect- transform methods using perceptual criteria. J Appl Crystallogr. 1992;25:495–503.
-
(1992)
J Appl Crystallogr
, vol.25
, pp. 495-503
-
-
Svergun, D.I.1
-
44
-
-
0033001996
-
Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing
-
Svergun DI. Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. Biophys J. 1999;76:2879–2886.
-
(1999)
Biophys J
, vol.76
, pp. 2879-2886
-
-
Svergun, D.I.1
-
45
-
-
33645214738
-
ATSAS 2.1, a program package for small-angle scattering data analysis
-
Konarev PV, Petoukhov MV, Volkov VV, Svergun DI. ATSAS 2.1, a program package for small-angle scattering data analysis. J Appl Crystallol. 2006–39:277–286.
-
(2006)
J Appl Crystallol
, vol.39
, pp. 277-286
-
-
Konarev, P.V.1
Petoukhov, M.V.2
Volkov, V.V.3
Svergun, D.I.4
-
46
-
-
37149049312
-
X-ray solution scattering (SAXS) combined with crystallography and computation: Defining accurate macromolecular structures, conformations and assemblies in solution
-
Putnam CD, Hammel M, Hura GL, Tainer JA. X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Q Rev Biophys. 2007 40:191–285.
-
(2007)
Q Rev Biophys
, vol.40
, pp. 191-285
-
-
Putnam, C.D.1
Hammel, M.2
Hura, G.L.3
Tainer, J.A.4
-
47
-
-
75749096748
-
Recognition by the thyroid hormone receptor of canonical DNA response elements
-
Figueira ACM, Lima LMTR, Lima, LHF, Ranzani AT, Mule GS, Polikarpov I. Recognition by the thyroid hormone receptor of canonical DNA response elements. Biochemistry. 2010;49:893–904.
-
(2010)
Biochemistry
, vol.49
, pp. 893-904
-
-
Figueira, A.1
Lima, L.2
Lima, L.3
Ranzani, A.T.4
Mule, G.S.5
Polikarpov, I.6
-
48
-
-
0028867731
-
The ligand binding domain of the human retinoic acid receptor _ is predominantly _-helical with a Trp residue in the ligand binding site
-
Lupisella JA, Driscoll JE, Metzler WJ, Reckzec PR. The ligand binding domain of the human retinoic acid receptor _ is predominantly _-helical with a Trp residue in the ligand binding site. J Biol Chem. 1995;270:24884–24890.
-
(1995)
J Biol Chem
, vol.270
, pp. 24884-24890
-
-
Lupisella, J.A.1
Driscoll, J.E.2
Metzler, W.J.3
Reckzec, P.R.4
-
49
-
-
82055185689
-
Small Molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1
-
Wang Y, Lonard DM, Yu Y, Chow D-C, Palzkill TG, O’Malley BW. Small Molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1. Mol Endocrinol. 2011;25:2041–2053.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 2041-2053
-
-
Wang, Y.1
Lonard, D.M.2
Yu, Y.3
Chow, D.-C.4
Palzkill, T.G.5
O’Malley, B.W.6
-
50
-
-
77950865952
-
Fluorescence quenching to study protein-ligand binding
-
van de Weert M. Fluorescence quenching to study protein-ligand binding. J Fluoresc. 2010;20:625–629.
-
(2010)
J Fluoresc
, vol.20
, pp. 625-629
-
-
Van De Weert, M.1
-
51
-
-
0032511086
-
Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors
-
Feng W, Ribeiro RCJ, Wagner RL, et al. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science. 1998;5370:1747–1749.
-
(1998)
Science
, vol.5370
, pp. 1747-1749
-
-
Feng, W.1
Ribeiro, R.2
Wagner, R.L.3
-
52
-
-
34250325134
-
Thyroid hormone response element organization dictates the composition of active receptor
-
Velasco LF, Togashi M, Walfish PG, et al. Thyroid hormone response element organization dictates the composition of active receptor. J Biol Chem. 2007;282:12458–12466.
-
(2007)
J Biol Chem
, vol.282
, pp. 12458-12466
-
-
Velasco, L.F.1
Togashi, M.2
Walfish, P.G.3
-
53
-
-
0035805580
-
Definition of the surface in the thyroid hormone receptor ligand binding domain for association as homodimers and heterodimers with retinoid X receptor
-
Ribeiro RCJ, Feng W, Wagner RL, et al. Definition of the surface in the thyroid hormone receptor ligand binding domain for association as homodimers and heterodimers with retinoid X receptor. J Biol Chem. 2001;276:14987–14995.
-
(2001)
J Biol Chem
, vol.276
, pp. 14987-14995
-
-
Ribeiro, R.1
Feng, W.2
Wagner, R.L.3
-
54
-
-
78650854003
-
Analysis of agonist and antagonist effects on thyroid hormone receptor confor-mation by hydrogen/deuterium exchange
-
Figueira ACM, Saidemberg DM, Souza PCT, et al. Analysis of agonist and antagonist effects on thyroid hormone receptor confor-mation by hydrogen/deuterium exchange. Mol Endocrinol. 2011; 25:15–31.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 15-31
-
-
Figueira, A.1
Saidemberg, D.M.2
Souza, P.3
-
55
-
-
0031726811
-
A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators
-
Tagami T, Gu W-X, Peairs PT, West BL, Jameson JL. A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators. Mol Endocrinol. 1998;12:1888–1902.
-
(1998)
Mol Endocrinol
, vol.12
, pp. 1888-1902
-
-
Tagami, T.1
Gu, W.-X.2
Peairs, P.T.3
West, B.L.4
Jameson, J.L.5
-
56
-
-
0029012163
-
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
-
Bourguet W, Ruff M, Chambom P, Gronemeyer H, Moras D. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α. Nature. 1995;375:377–382.
-
(1995)
Nature
, vol.375
, pp. 377-382
-
-
Bourguet, W.1
Ruff, M.2
Chambom, P.3
Gronemeyer, H.4
Moras, D.5
-
57
-
-
33748929006
-
Thermofluor-based high-throughput stability optimization of proteins for structural studies
-
Ericsson UB, Hallberg BM, Detitta GT, Dekker N, Nordlund P. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Anal Biochem. 2006;357:289–298.
-
(2006)
Anal Biochem
, vol.357
, pp. 289-298
-
-
Ericsson, U.B.1
Hallberg, B.M.2
Detitta, G.T.3
Dekker, N.4
Nordlund, P.5
-
58
-
-
33646878290
-
Human thyroid receptor forms tetramers in solution, which dissociate into dimers upon ligand binding
-
Figueira AC, Dias SM, Santos MA, et al. Human thyroid receptor forms tetramers in solution, which dissociate into dimers upon ligand binding. Cell Biochem Biophys. 2006;44:453–462.
-
(2006)
Cell Biochem Biophys
, vol.44
, pp. 453-462
-
-
Figueira, A.C.1
Dias, S.M.2
Santos, M.A.3
-
59
-
-
0028786255
-
On the role of ligand in retinoid signaling: Positive cooperativity in the interactions of 9-cis retinoic acid with tetramers of the retinoid X receptor
-
Kersten S, Pan L, Noy N. On the role of ligand in retinoid signaling: positive cooperativity in the interactions of 9-cis retinoic acid with tetramers of the retinoid X receptor. Biochemistry. 1995;34: 14263–14269.
-
(1995)
Biochemistry
, vol.34
, pp. 14263-14269
-
-
Kersten, S.1
Pan, L.2
Noy, N.3
-
60
-
-
0026760460
-
Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid
-
Zhang X, Lehmann J, Hoffmann B, et al. Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature. 1992; 358:587–591.
-
(1992)
Nature
, vol.358
, pp. 587-591
-
-
Zhang, X.1
Lehmann, J.2
Hoffmann, B.3
-
61
-
-
0027488078
-
Formation of retinoid X receptor homodimers leads to repression of T3 response: Hormonal cross talk by ligand-induced squelching
-
Lehmann J, Zhang X, Graupner G, et al. Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching. Mol Cell Biol. 1993;13: 7698–7707.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7698-7707
-
-
Lehmann, J.1
Zhang, X.2
Graupner, G.3
-
63
-
-
0034957480
-
Nuclear hormone receptors and gene expression
-
Aranda A, Pascual A. Nuclear hormone receptors and gene expression. Physiol Rev. 2001;81:1269–1304.
-
(2001)
Physiol Rev
, vol.81
, pp. 1269-1304
-
-
Aranda, A.1
Pascual, A.2
-
64
-
-
0026551704
-
RXRα, a promiscuous partner of retinoid acid and thyroid hormone receptors
-
Bugge TH, Pohl J, Lonnoy O, Stunnenberg HG. RXRα, a promiscuous partner of retinoid acid and thyroid hormone receptors. EMBO J. 1992;11:1409–1418.
-
(1992)
EMBO J
, vol.11
, pp. 1409-1418
-
-
Bugge, T.H.1
Pohl, J.2
Lonnoy, O.3
Stunnenberg, H.G.4
-
65
-
-
0026536522
-
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoid acid receptors
-
Zhang XK, Hoffmann B, Tran PB, Graupner G, Pfahl M. Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoid acid receptors. Nature. 1992;355:441–446.
-
(1992)
Nature
, vol.355
, pp. 441-446
-
-
Zhang, X.K.1
Hoffmann, B.2
Tran, P.B.3
Graupner, G.4
Pfahl, M.5
-
66
-
-
0037050017
-
Coregulator recruitment and the mechanism of retinoid acid receptor synergy
-
Germains P, Iyer J, Zechel C, Gronemeyer H. Coregulator recruitment and the mechanism of retinoid acid receptor synergy. Nature. 2002;415:187–192.
-
(2002)
Nature
, vol.415
, pp. 187-192
-
-
Germains, P.1
Iyer, J.2
Zechel, C.3
Gronemeyer, H.4
-
67
-
-
78649771898
-
The “phantom effect” of the rexinoid LG100754: Structural and functional insights
-
Sato Y, Ramalanjaona N, Huet T, et al. The “phantom effect” of the rexinoid LG100754: structural and functional insights. PLoS One. 2010;5:e15119.
-
(2010)
Plos One
, vol.5
-
-
Sato, Y.1
Ramalanjaona, N.2
Huet, T.3
-
68
-
-
0025186267
-
Interactions among a subfamily of nuclear hormone receptors: The regulatory zipper model
-
Forman BM, Samuels HH. Interactions among a subfamily of nuclear hormone receptors: the regulatory zipper model. Mol Endocrinol. 1990;4:1293–1301.
-
(1990)
Mol Endocrinol
, vol.4
, pp. 1293-1301
-
-
Forman, B.M.1
Samuels, H.H.2
-
69
-
-
1642304065
-
Structural determinants of allosteric ligand activation in RXR heterodimers
-
Shulman AI, Larson C, Mangelsdorf DJ, Ranganathan R. Structural determinants of allosteric ligand activation in RXR heterodimers. Cell. 2004;116:417–429.
-
(2004)
Cell
, vol.116
, pp. 417-429
-
-
Shulman, A.I.1
Larson, C.2
Mangelsdorf, D.J.3
Ranganathan, R.4
-
70
-
-
8844262660
-
Principles for modulation of the nuclear receptor superfamily
-
Gronemeyer H, Gustafsson JA, Laudet V. Principles for modulation of the nuclear receptor superfamily. Nat Rev. 2004;3:950–964.
-
(2004)
Nat Rev
, vol.3
, pp. 950-964
-
-
Gronemeyer, H.1
Gustafsson, J.A.2
Laudet, V.3
-
71
-
-
0031043055
-
The phantom ligand effect: Allosteric control of transcription by the retinoid X receptor
-
Schulman IG, Li C, Shwabe JWR, Evans RM. The phantom ligand effect: allosteric control of transcription by the retinoid X receptor. Genes Dev. 1997;11:299–308.
-
(1997)
Genes Dev
, vol.11
, pp. 299-308
-
-
Schulman, I.G.1
Li, C.2
Shwabe, J.3
Evans, R.M.4
-
72
-
-
0027460433
-
Divergent effects os 9-cis-retinoic acid receptor on positive and negative thyroid hormone receptor-dependent gene expression
-
Hallenbeck PL, Phyillaier M, Nikodem VM. Divergent effects os 9-cis-retinoic acid receptor on positive and negative thyroid hormone receptor-dependent gene expression. J Biol Chem. 1993;268: 3825–3828.
-
(1993)
J Biol Chem
, vol.268
, pp. 3825-3828
-
-
Hallenbeck, P.L.1
Phyillaier, M.2
Nikodem, V.M.3
-
73
-
-
37749048568
-
The search for non-chordate retinoic acid signaling: Lessons from chordates
-
Simões-Costa MS, Azambuja AP, Xavier Neto J. The search for non-chordate retinoic acid signaling: lessons from chordates. J. Exp. Zool. 2008;310B:54–72.
-
(2008)
J. Exp. Zool
, vol.310
, pp. 54-72
-
-
Simões-Costa, M.S.1
Azambuja, A.P.2
Xavier Neto, J.3
-
74
-
-
0032505096
-
Ligand binding and coactivator assembly of the peroxisome proliferator-activated receptor- γ
-
Nolte RT, Wisley GB, Westin S, et al. Ligand binding and coactivator assembly of the peroxisome proliferator-activated receptor- γ. Nature. 1998;395:137–143.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisley, G.B.2
Westin, S.3
-
75
-
-
0029030016
-
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T 18
-
Le Douarin B, Zechel C, Garnier JM, et al. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T 18. EMBO J. 1995;14:2020–2033.
-
(1995)
EMBO J
, vol.14
, pp. 2020-2033
-
-
Le Douarin, B.1
Zechel, C.2
Garnier, J.M.3
-
76
-
-
0033744048
-
Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-_ and estrogen receptor-_: Correlations with biological character and distinct differences among SRC coactivator family members
-
Kraichely DM, Sun J, Katzenellenbogen JA, Katzenellenbogen BS. Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-_ and estrogen receptor-_: correlations with biological character and distinct differences among SRC coactivator family members. Endocrinology. 2000;141:3534–3545.
-
(2000)
Endocrinology
, vol.141
, pp. 3534-3545
-
-
Kraichely, D.M.1
Sun, J.2
Katzenellenbogen, J.A.3
Katzenellenbogen, B.S.4
-
77
-
-
0036185782
-
Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements
-
Hall JM, McDonnell P, Korach KS. Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements. Mol Endocrinol. 2002;16: 469–486.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 469-486
-
-
Hall, J.M.1
McDonnell, P.2
Korach, K.S.3
-
78
-
-
81155132258
-
Structural dynamics, intrinsic disorder, and allostery in nuclear receptors as transcription factors
-
Hilser VJ, Thompson EB. Structural dynamics, intrinsic disorder, and allostery in nuclear receptors as transcription factors. J Biol Chem. 2011;286:39675–39682.
-
(2011)
J Biol Chem
, vol.286
, pp. 39675-39682
-
-
Hilser, V.J.1
Thompson, E.B.2
-
79
-
-
79955586601
-
DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex
-
Zhang J, Chalmers MJ, Stayrook KR, et al. DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex. Nat Struct Mol Biol. 2011;18:556–564.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 556-564
-
-
Zhang, J.1
Chalmers, M.J.2
Stayrook, K.R.3
-
80
-
-
77749323466
-
Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain
-
Varlakhanova N, Snyder C, Jose S, Hahm JB, Privalsky ML. Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain. Mol Cell Biol. 2010;30:1434–1445.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 1434-1445
-
-
Varlakhanova, N.1
Snyder, C.2
Jose, S.3
Hahm, J.B.4
Privalsky, M.L.5
-
81
-
-
0029790142
-
Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator
-
McInerney EM, Tsai MJ, O’Malley BW, Katzenellenbogen BS. Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator. Proc Natl Acad Sci USA. 1996; 93:10069–10073.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10069-10073
-
-
McInerney, E.M.1
Tsai, M.J.2
O’Malley, B.W.3
Katzenellenbogen, B.S.4
-
82
-
-
0032524634
-
The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1(AF1) and AF2 domains of steroid receptors
-
Oñate SA, Boonyaratanakornkit V, Spencer TE, et al. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1(AF1) and AF2 domains of steroid receptors. J Biolsuppl Chem. 1998;273:12101–12108.
-
(1998)
J Biolsuppl Chem
, vol.273
, pp. 12101-12108
-
-
Oñate, S.A.1
Boonyaratanakornkit, V.2
Spencer, T.E.3
|