Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange

Molecular Endocrinology

Volumn 25, Issue 1, 2011, Pages 15-31

  Figueira, A C M ^a,b   Saidemberg, D M ^c   Souza, P C T ^d   Martinez L ^d   Scanlan, T S ^e   Baxter, J D ^f   Skaf, M S ^d   Palma, M S ^c   Webb, P ^f   Polikarpov, I ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b BRAZILIAN CENTER FOR RESEARCH IN ENERGY AND MATERIALS CNPEM   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^d UNIVERSITY OF CAMPINAS   (Brazil)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; AMMONIA; BINDING PROTEIN; DEUTERIUM; DIMER; HORMONE RECEPTOR AFFECTING AGENT; HORMONE RECEPTOR BLOCKING AGENT; HYDROGEN; LIGAND; LIGAND BINDING PROTEIN; PEPTIDE; SOLVENT; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR AGONIST; THYROID HORMONE RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; DIMERIZATION; FEMALE; HUMAN; HUMAN CELL; LIGAND BINDING; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SURFACE PROPERTY;

AMINO ACID SEQUENCE; AMMONIA; APOPROTEINS; DEUTERIUM; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THYROID HORMONE; SEQUENCE ALIGNMENT; SOLVENTS; TRIIODOTHYRONINE;

EID: 78650854003     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0202     Document Type: Article

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