Matrix metalloproteinase-14 both sheds cell surface neuronal glial antigen 2 (NG2) proteoglycan on macrophages and governs the response to peripheral nerve injury

Journal of Biological Chemistry

Volumn 290, Issue 6, 2015, Pages 3693-3707

  Nishihara, Tasuku ^a,b,d   Remacle, Albert G ^c   Angert, Mila ^a,b   Shubayev, Igor ^b   Shiryaev, Sergey A ^c   Liu, Huaqing ^a,b   Dolkas, Jennifer ^a,b   Chernov, Andrei V ^c   Strongin, Alex Y ^c   Shubayev, Veronica I ^a,b  

^a University of California   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c BURNHAM INSTITUTE   (United States)

^d EHIME UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; CELL CULTURE; CELL MEMBRANES; ENZYME ACTIVITY; MACROPHAGES; MONOCLONAL ANTIBODIES; NEURONS; TISSUE;

CHONDROITIN SULFATES; FLUORESCENT REPORTER; HUMAN MONOCLONAL ANTIBODIES; MATRIX METALLOPROTEINASES; PERIPHERAL NERVOUS SYSTEM; SPATIO-TEMPORAL RELATIONSHIPS; TISSUE INHIBITOR OF METALLOPROTEINASES-2; TRANSCRIPTION FACTOR-3;

BLOOD VESSELS;

CELL ANTIGEN; CYCLIC AMP DEPENDENT TRANSCRIPTION FACTOR 3; FLUORESCENT DYE; GELATINASE A; GELATINASE B; LAMININ; MATRIX METALLOPROTEINASE 14; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DX 2400; NEUROMODULIN; NEURONAL GLIAL ANTIGEN 2; PLACEBO; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ANTIGEN; CHONDROITIN SULFATE PROTEOGLYCAN 4; MMP2 PROTEIN, RAT; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; DRUG PROTEIN BINDING; DRUG TARGETING; EMBRYO; ENZYME INHIBITION; ENZYME SPECIFICITY; FEMALE; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE CULTURE; MALE; MYELINATION; NERVE CELL CULTURE; NERVE CRUSH; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NEUROPROTECTION; NONHUMAN; PERIPHERAL NERVE INJURY; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RANVIER NODE; RAT; RAT MODEL; REPORTER GENE; SCHWANN CELL; TISSUE DISTRIBUTION; UPREGULATION; ANIMAL; CELL CULTURE; CELL MEMBRANE; EXTRACELLULAR SPACE; GENETICS; HEK293 CELL LINE; INJURIES; MCF 7 CELL LINE; METABOLISM; NERVE FIBER; NERVE REGENERATION; PATHOPHYSIOLOGY; PHYSIOLOGY; SCIATIC NERVE; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTIGENS; AXONS; CELL MEMBRANE; CELLS, CULTURED; EXTRACELLULAR SPACE; FEMALE; GAP-43 PROTEIN; HEK293 CELLS; HUMANS; LAMININ; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MCF-7 CELLS; NERVE REGENERATION; PERIPHERAL NERVE INJURIES; PROTEOGLYCANS; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; SCHWANN CELLS; SCIATIC NERVE;

EID: 84922308838     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.603431     Document Type: Article

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