Non-destructive and selective imaging of the functionally active, pro-invasivemembrane type-1 matrix metalloproteinase (MT1-MMP) enzyme in cancer cells

Journal of Biological Chemistry

Volumn 288, Issue 28, 2013, Pages 20568-20580

  Remacle, Albert G ^a   Shiryaev, Sergey A ^a   Golubkov, Vladislav S ^a   Freskos, John N ^b   Brown, Michael A ^b   Karwa, Amolkumar S ^b   Naik, Arati D ^b   Howard, Carol P ^b   Sympson, Carolyn J ^b   Strongin, Alex Y ^a  

^a BURNHAM INSTITUTE   (United States)

^b MALLINCKRODT PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT REPORTER; IMMUNOHISTOCHEMISTRY; LABORATORY STUDIES; MATRIX METALLOPROTEINASES; PROGNOSTIC APPROACH; PROTEOLYTIC ACTIVITIES; QUANTITATIVE IMAGING; SELECTIVE IMAGING;

CELL MEMBRANES; ONCOLOGY; PROTEOLYSIS;

ENZYME INHIBITION;

FLUOROCHROME; HYDROXAMIC ACID; LIPOSOME; MACROGOL; MATRIX METALLOPROTEINASE 14; MP 3653; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CARCINOMA; CANCER CELL; CATALYSIS; CELL COMPARTMENTALIZATION; CELL LEVEL; CELL SURFACE; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROSARCOMA; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; INTERNALIZATION; MELANOMA; MOLECULAR IMAGING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; PROTEIN TRANSPORT;

BREAST CANCER; CANCER BIOLOGY; DRUG DELIVERY; ENZYME INHIBITORS; HYDROXAMATE INHIBITORS; IMAGING; LIPOSOMES; MATRIX METALLOPROTEINASE (MMP); MT1-MMP; PROTEASE INHIBITOR;

ANIMALS; BINDING, COMPETITIVE; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; FLUORESCEINS; FLUORESCENT DYES; HEK293 CELLS; HUMANS; LIPOSOMES; MATRIX METALLOPROTEINASE 14; MCF-7 CELLS; MICROSCOPY, FLUORESCENCE; MOLECULAR IMAGING; MUTATION; NEOPLASMS; OPTICAL IMAGING; ORGANIC CHEMICALS; PROTEIN BINDING; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 84880047527     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.471508     Document Type: Article

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