Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: The major axon-inhibitory proteoglycan is NG2

Journal of Neuroscience

Volumn 19, Issue 20, 1999, Pages 8778-8788

  Fidler, Penny S ^a   Schuette, Katrin ^b   Asher, Richard A ^a   Dobbertin, Alexandre ^b   Thornton, Suzanne R ^c   Calle Patino, Yolanda ^c   Muir, Elizabeth ^a   Levine, Joel M ^d   Geller, Herbert M ^c   Rogers, John H ^a   Faissner, Andreas ^b,e   Fawcett, James W ^a,f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d Stony Brook University   (United States)

^e CNRS   (France)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Axon regeneration; Chondroitin sulfate; Extracellular matrix; NG2; Proteoglycans; Versican

Indexed keywords

PROTEOCHONDROITIN SULFATE; PROTEOGLYCAN; VERSICAN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL LINE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GLIA CELL; GROWTH INHIBITION; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SPINAL GANGLION;

EID: 0033570333     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-20-08778.1999     Document Type: Article

References (44)

1. Asher R, Perides G, Vanderhacghen J-J, Bignami A (1991) Extracellular matrix of central nervous system white matter: demonstration of an hyaluronate-protein complex. J Neurosci Res 28:410-421.
2. Asher RA, Scheibe RJ, Reiser HD, Bignami A (1995) On the existence of a cartilage-like proteoglycan and link proteins in the central nervous system. Glia 13:294-308.
3. Braunewell KH, Pesheva P, McCarthy JB, Furcht LT, Schmilz B, Schachner M (1995) Functional involvement of sciatic nerve-derived versican and decorin-like molecules and other chondroitin sulfate proteoglycans in ecm-mediated cell-adhesion and neurite outgrowth. Eur J Neurosci 7:805-814.
4. Burg MA, fillet E, Timpl R, Stallcup WB (1996) Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules. J Biol Chem 271:26110-26116.
5. Davies SJA, Fitch MT, Membcrg SP, Hall AK, Raisman G, Silver J (1997) Regeneration of adult axons in white matter tracts of the central nervous system. Nature 390:680-684.
6. Dou CL, Levine JM (1994) Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan. J Neurosci 14:7616-7628.
7. Dou CL, Levine JM (1997) Identification of a neuronal cell surface receptor for a growth inhibitory chondroitin sulfate proteoglycan (NG2). J Neureichem 68:1021-1030.
8. Faissner A (1997) The tenascin gene family in axon growth and guidance. Cell Tissue Res 290:331-341.
9. Faissner A, Clement A, Lochter A, Streit A, Mandl C, Schachner M (1994) Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties. J Cell Biol 126:783-799.
10. Fawcett JW (1997) Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system. Cell Tissue Res 290:371-377.
11. Fawcett JW, Housden E, Smith-Thomas L, Meyer RL (1989) The growth of axons in three dimensional astrocytc cultures. Dev Biol 135:449-458.
12. Fok-Seang J, Smith-Thomas L, Muir E, Du J-S, Housden E, Johnson AR, Faissner A, Geller HM, Keynes RJ, Rogers JH, Fawcett JW (1995) An analysis of astrocvtic cell lines with different abilities to promote axon growth. Brain Res 689:207-223.
13. Geller HM, Dubois-Dalcq M (1988) Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector. J Cell Biol 107:1977-1986.
14. Grierson JP, Petroski RE, Ling DSF, Geller HM (1990) Astrocyte topography and tenascin/cytotactin expression: correlation with the ability to support neuritic outgrowth. Dev Brain Res 55:11-19.
15. Grill RJ, Stallcup W B, Tuszynski M H (1998) Temporal upregulation and spatial distribution of putative inhibitory and growth permissive substrate molecules in the injured adult rat spinal cord. Soc Neurosci Abstr 24:1054.
16. Henderson DJ, Ybot-Gonzalez P, Copp AJ (1997) Over-expression of the chondroitin sulfate proteoglycan versican is associated with defective neural crest migration in the pax3 mutant mouse (splotch). Mech Dev 69:39-51.
17. Hinkle DA, Harney JP, Cai A, Hilt DC, Yarowsky PJ, Wise PM (1998) Basic fibroblast growth factor-2 and interleukin-lβ regulate S100 expression in cultured astrocytes. Neuroscience 82:33-41.
18. Keirstead HS, Levine JM, Blakemore WF (1998) Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord. Glia 22:161-170.
19. Landolt RM, Vaughan L, Winterhalter KH, Zimmermann DR (1995) Versican is selectively expressed in embryonic tissues that act as barriers to neural crest cell migration and axon outgrowth. Development 121:2303-2312.
20. Levine JM (1994) Increased expression of the ng2 chondroitin-sulfate proteoglycan after brain injury. J Neurosci 14:4716-4730.
21. Levine JM, Nishiyama A (1996) The NG2 chondroitin sulfate proteoglycan: a multifunctional proteoglycan associated with immature cells. Perspect Dev Neurobiol 3:245-259.
22. McKeon RJ, Schreiber RC, Rudge JS, Silver J (1991) Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J Neurosci 11:3398-3411.
23. McKerrachcr L, David S, Jackson DL, Kottis V, Dunn RJ, Braun PE (1994) Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron 13:805-811.
24. Morris EJ, Geller HM (1996) Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell-cycle independent toxicity. J Cell Biol134:757-770.
25. MuirD (1994) Metalloproteinase-dependent neurite outgrowth within a synthetic extracellular-matrix is induced by nerve growth-factor. Exp Cell Res 210:243-252.
26. Mukhopadhay G, Doherty P, Walsh FS, Cracker PR, Filbin MT (1994) A novel role for myelin associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13:757-767.
27. Naso MF, Zimmermann DR, lozzo RV (1994) Characterization of the complete genomic structure of the human versican gene and functional analysis of its promoter. J Biol Chem 269:32999-33008.
28. Nishiyama A, Lin XH, Stallcup WB (1995) Generation of truncated forms of the ng2 proteoglycan by cell- surface proteolysis. Mol Biol Cell 6:1819-1832.
29. Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB (1996a) Co-localization of NG2 proteoglycan and PDGF a-receptor on O2A progenitor cells in the developing rat brain. J Neurosci Res 43:299-314.
30. Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB (1996b) Interaction between NG2 proteoglycan and PDGF a-receptor on O2A progenitor cells is required for optimal response to PDGF. J Neurosci Res 43:315-330.
31. Perris R, Perissinotto D, Pettway Z, Bronner FM, Morgelin M, Kimata K (1996) Inhibitory effects of PG-H/aggrecan and PG-M/versican on avian neural crest cell migration. FASEB J 10:293-301.
32. Pesheva P, Gennarini G, Goridis C, Schachner M (1993) The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein Jl-160/180. Neuron 10:69-82.
33. Petroski RE, Geller HM (1994) Selective labeling of embryonic neurons cultured on astrocyte monolayers with 5(6)-carboxyfluorescein diacetate (CFDA). J Neurosci Methods 52:23-32.
34. Pindzola RR, Doller C, Silver J (1993) Putaive inhibitory extracellular matrix molecules at the dorsal root entry zone of the spinal cord during development and after root and sciatic nerve lesions. Dev Biol 156:34-48.
35. Powell EM, Fawcett JW, Geller HM (1997) Proteoglycans provide neurite guidance at an astrocyte bourdary. Mol Cell Neurosci 10:27-42.
36. Rabchevsky AG, Streit WJ (1997) Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth. J Neurosci Res 47:34-48.
37. Reynolds R, Hardy R (1997) Oligodendroglial progenitors labeled with the O4 antibody persist in the adult rat cerebral cortex in vivo. J Neurosci Res 47:455-470.
38. Schwab ME, Kapf hammer JP, Bandtlow CE (1993) Inhibitors of neurite growth. Annu Rev Neurosci 16:565-595.
39. Smith-Thomas L, Fok-Seang J, Stevens J, Du J-S, Muir E, Faissner A, Geller HM, Rogers JH, Fawcett JW (1994) An inhibitor of neurite outgrowth produced by astrocytes. J Cell Sci 107:1687-1695.
40. Smith-Thomas L, Stevens J, Fok-Seang J, Muir E, Faissner A, Rogers JH, Fawcett JW (1995) Increased axon regeneration in astrocytes grown in the presence of proteoglycan synthesis inhibitors. J Cell Sci 108:1307-1315.
41. Snow DM, Letourneau PC (1992) Neurite outgrowth on a step gradient of chondroitin sulfate proteoglycan (CS-PG). J Neurobiol 23:322-336.
42. Snow DM, Lemmon V, Carrino DA, CaplanAl, Silver] (1990) Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro. ExpNeurol 109:111-130.
43. Sorrell JM, Carrino DA, Caplan AI (1993) Structural domains in chondroitin sulfate identified by anti-chondroitin sulfate monoclonal antibodies. Immunosequencing of chondroitin sulfates. Matrix 13:351-361.
44. Zimmermann DR, Ruoslahti E (1989) MuHple domains of the large fibroblast proteoglycan, versican. EMBO J 8:2975-2981.