Deposition of the NG2 proteoglycan at nodes of Ranvier in the peripheral nervous system

Journal of Neuroscience

Volumn 21, Issue 20, 2001, Pages 8119-8128

  Martin, S ^a   Levine, A K ^a   Chen, Z J ^a   Ughrin, Y ^a   Levine, J M ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Chondroitin sulfate proteoglycan; Extracellular matrix; Nerve blood barrier; NG2; Node of Ranvier; Perineurium

Indexed keywords

CELL ADHESION MOLECULE; ION CHANNEL; MEMBRANE PROTEIN; PROTEIN CASPR; PROTEIN NG2; PROTEOCHONDROITIN SULFATE; PROTEOGLYCAN; SODIUM CHANNEL; SODIUM ION; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BRAIN REGION; CELL ADHESION; CELL DENSITY; CELLULAR DISTRIBUTION; FIBROBLAST; GLIA CELL; GROWTH INHIBITION; IMMUNOHISTOCHEMISTRY; MYELINATION; NONHUMAN; PERINEURIUM; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEOGLYCAN SYNTHESIS; RANVIER NODE; RAT; SCHWANN CELL; SCIATIC NERVE; VOLTAGE CLAMP;

EID: 0035887892     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-20-08119.2001     Document Type: Article

References (60)

1. On the molecular architecture of myelinated fibers
2. Neurexin IV, caspr and paranodin - Novel members of the neurexin family: Encounters of axons and glia
3. Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus
4. Tissue localization of nerve growth factor and nerve growth factor receptors
5. Neural architecture in transected rabbit sciatic nerve after prolonged nonreinnervation
6. Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve
7. Schwann cell regulation of extracellular matrix synthesis and assembly
8. Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules
9. Cells expressing the NG2 antigen contact nodes of Ranvier in adult CNS white matter
10. v1.6 is loclaized at nodes of Ranvier, dendrites and synapses
11. Schwann cell synthesize type V collagen that contains a novel α4 chain
12. Molecular composition of the node of Ranvier: Identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain) and NrCAM at nodal axon segments
13. Inhibition of neurite growth by the NG2 chondroitin-sulfate proteoglycan
14. The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination
15. Peripheral nerve regeneration
16. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: The major axon-inhibitory proteoglycan is NG2
17. Glial cell extracellular matrix: Boundaries for axon growth in development and regeneration
18. The fine structure of stumps of transected nerve fibers in subserial sections
19. Schwann cell basal lamina and nerve regeneration
20. Schwann cell precursors and their development
21. Ankyrin G. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier
22. Morphogenesis of the node of Ranvier, coclusters of ankyrin and ankyrin binding proteins define early developmental intermediates
23. Light and electron microscope localization a cell surface antigen (NG2) in the rat cerebellum: Association with smooth protoplasmic astrocytes
24. The NG2 chondroitin sulfate proteoglycan; A multifunctional proteoglycan associated with immature cells
25. Development and differentiation of glial precursor cells in the rat cerebellum
26. Reactions of oligodendrocyte precursor cells to alpha herpesvirus infection of the central nervous system
27. Sodium channel β subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact
28. Enhanced expression of the extracellular matrix molecule J1/tenascin in the regenerating adult mouse sciatic nerve
29. Effect of a conditioning lesion on axonal sprout formation at nodes of Ranvier
30. Paranodin, a glycoprotein of neuronal paranodal membranes
31. Differential distribution of closely related potassium channels in rat Schwann cells
32. Neurexins: Three genes and 1001 products
33. Expression of the chondroitin sulfate proteoglycan NG2 in normal and regenerating peripheral nerve
34. Regenerative changes in rat dorsal roots following Wallerian degeneration
35. The primary structure of NG2: A novel membrane spanning proteoglycan
36. Generation of truncated forms of the NG2 proteoglycan by cell surface proteolysis
37. Addition of purified basal lamina molecules enables Schwann cell ensheathment of sympathetic neurites in culture
38. Microenvironment of the peripheral nervous system under normal and pathological conditions
39. A light and electron microscopic analysis of NG2 positive oligodendrocyte precursor cells in the normal and kainate lesioned hippocampus
40. Molecular domains of myelinated axons
41. Perineurial cells in culture, an immunocytochemical and electron microscopic study
42. Type VI collagen, in situ hybridization and imnohistochemistry reveal abundant mRNA and protein levels in human neurofibroma, schwannoma and normal peripheral nerve tissues
43. Ion channel sequestration in central nervous system axons
44. Potassium channel distribution, clustering, and function in remyelinating rat axons
45. Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS
46. Agrin-like molecules at synaptic sites in normal, denervated and damaged skeletal muscles
47. Neuronal cell adhesion molecules and cytotactin are colocalized at nodes of Ranvier
48. Caspr and contactin form a complex that is targeted to the paranodal junctions during myelination
49. Intramembranous particle distribution at the node of Ranvier and adjacent axolemma in myelinated axons of the frog brain
50. The extracellular matrix of the central and peripheral nervous system: Structure and function
51. Molecular heterogeneity of basal laminae: Isoforms of laminin and collagenIV at the neuromuscular junction and elsewhere
52. The AN2 protein is a marker for the Schwann cell lineage expressed by immature and nonmyelinating Schwann cells
53. Cell surface molecules that characterize different stages in the development of cerebellar interneurons
54. Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α-dystroglycan and several extracellular matrix proteins
55. Expression of human nerve growth factor receptor on cells derived from all three germ layers
56. The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein
57. Multiple globular domains of the NG2 proteoglycan core protein mediate axon growth inhibition
58. Ion channel redistribution and function during development of the myelinated axon
59. Alternate splicing of human NrCAM in neural and nonneural tissues
60. Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons