Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP): The role of the cytoplasmic tail Cys574, the active site Glu 240, and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 25705-25714

  Rozanov, Dmitry V ^a   Deryugina, Elena I ^a   Ratnikov, Boris I ^a   Monosov, Edward Z ^a   Marchenko, George N ^a   Quigley, James P ^b   Strongin, Alex Y ^a  

^a BURNHAM INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; ENZYMES; MUTAGENESIS; OLIGOMERS;

CELL LOCOMOTION;

BIOCHEMISTRY;

CYSTEINE; FURIN; GELATINASE A; GLUTAMIC ACID; HYDROXAMIC ACID; ILOMASTAT; MATRIX METALLOPROTEINASE 14; MATRIX PROMETALLOPROTEINASE 2; MATRIXIN LIKE PROTEINASE; MONOMER; MUTANT PROTEIN; OLIGOMER; UNCLASSIFIED DRUG; DIPEPTIDE; GLUTAMINE; INDOLE DERIVATIVE; MATRIX METALLOPROTEINASE; METALLOPROTEINASE; PROTEINASE INHIBITOR;

AMINO ACID SUBSTITUTION; ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CATALYSIS; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; COVALENT BOND; DISULFIDE BOND; ENZYME ACTIVATION; ENZYME ACTIVE SITE; FIBROSARCOMA CELL; GENE MUTATION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PROCESSING; RRXR FURIN CLEAVAGE MOTIF; BREAST TUMOR; CHEMISTRY; DIMERIZATION; FEMALE; FIBROSARCOMA; GENETICS; METABOLISM; PATHOLOGY; SITE DIRECTED MUTAGENESIS;

BREAST NEOPLASMS; CYSTEINE; DIMERIZATION; DIPEPTIDES; DNA MUTATIONAL ANALYSIS; ENZYME ACTIVATION; FEMALE; FIBROSARCOMA; GLUTAMINE; HUMANS; INDOLES; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MUTAGENESIS, SITE-DIRECTED; PROTEASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 0035854654     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007921200     Document Type: Article

References (63)

1. Massova, I., Kotra, L. P., Fridman, R., and Mobashery, S. (1998) FASEB J. 12, 1075-1095
2. Nagase, H., and Woessner, J. F., Jr. (1999) J. Biol. Chem. 274, 21491-21494
3. Seiki, M. (1999) APMIS 107, 137-143
4. Polette, M., and Birembaut, P. (1998) Int. J. Biochem. Cell Biol. 30, 1195-1202
5. Ohuchi, E., Imai, K., Fujii, Y., Sato, H., Seiki, M., and Okada, Y. (1997) J. Biol. Chem. 272, 2446-2451
6. d'Ortho, M. P., Will, H., Atkinson, S., Butler, G., Messent, A., Gavrilovic, J., Smith, B., Timpl, R., Zardi, L., and Murphy, G. (1997) Eur. J. Biochem. 250, 751-757
7. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E., and Seiki, M. (1994) Nature 370, 61-65
8. Strongin, A. Y., Collier, I., Bannikov, G., Marmer, B. L., Grant, G. A., and Goldberg, G. I. (1995) J. Biol. Chem. 270, 5331-5338
9. Deryugina, E. I., Ratnikov, B., Monosov, E., Postnova, T. I., DiScipio, R., Smith, J. W., and Strongin, A. Y. (2001) Exp. Cell Res. 263, 209-223
10. Cao, J., Hymowitz, M., Conner, C., Bahou, W. F., and Zucker, S. (2000) J. Biol. Chem. 275, 29648-29653
11. Ellerbroek, S. M., Fishman, D. A., Kearns, A. S., Bafetti, L. M., and Stack, M. S. (1999) Cancer Res. 59, 1635-1641
12. Kinoshita, T., Sato, H., Okada, A., Ohuchi, E., Imai, K., Okada, Y., and Seiki, M. (1998) J. Biol. Chem. 273, 16098-16103
13. Lehti, K., Valtanen, H., Wickstrom, S., Lohi, J., and Keski-Oja, J. (2000) J. Biol. Chem. 275, 15006-15013
14. Hernandez-Barrantes, S., Toth, M., Bernardo, M. M., Yurkova, M., Gervasi, D. C., Raz, Y., Sang, Q. A., and Fridman, R. (2000) J. Biol. Chem. 275, 12080-12089
15. Urena, J. M., Merlos-Suarez, A., Baselga, J., and Arribas, J. (1999) J. Cell Sci. 112, 773-784
16. Maquoi, E., Frankenne, F., Baramova, E., Munaut, C., Sounni, N. E., Remacle, A., Noel, A., Murphy, G., and Foidart, J. M. (2000) J. Biol. Chem. 275, 11368-11378
17. Jo, Y., Yeon, J., Kim, H. J., and Lee, S. T. (2000) Biochem. J. 345, 511-519
18. Kurschat, P., Zigrino, P., Nischt, R., Breitkopf, K., Steurer, P., Klein, C. E., Krieg, T., and Mauch, C. (1999) J. Biol. Chem. 274, 21056-21062
19. Zucker, S., Drews, M., Conner, C., Foda, H. D., DeClerck, Y. A., Langley, K. E., Bahou, W. F., Docherty, A. J., and Cao, J. (1998) J. Biol. Chem. 273, 1216-1222
20. Butler, G. S., Butler, M. J., Atkinson, S. J., Will, H., Tamura, T., van Westrum, S. S., Crabbe, T., Clements, J., d'Ortho, M. P., and Murphy, G. (1998) J. Biol. Chem. 273, 871-880
21. Brooks, P. C., Silletti, S., von Schalscha, T. L., Friedlander, M., and Cheresh, D. A. (1998) Cell 92, 391-400
22. Deryugina, E. I., Bourdon, M. A., Jungwirth, K., Smith, J. W., and Strongin, A. Y. (2000) Int. J. Cancer 86, 15-23
23. Murphy, G., and Gavrilovic, J. (1999) Curr. Opin. Cell Biol. 11, 614-621
24. Crabbe, T., Zucker, S., Cockett, M. I., Willenbrock, F., Tickle, S., O'Connell, J. P., Scothern, J. M., Murphy, G., and Docherty, A. J. (1994) Biochemistry 33, 6684-6690
25. Pei, D., and Weiss, S. J. (1996) J. Biol. Chem. 271, 9135-9140
26. Cao, J., Rehemtulla, A., Bahou, W., and Zucker, S. (1996) J. Biol. Chem. 271, 30174-30180
27. Sato, T., Kondo, T., Fujisawa, T., Seiki, M., and Ito, A. (1999) J. Biol. Chem. 274, 37280-37284
28. Sato, T., Kondo, T., Seiki, M., and Ito, A. (1999) Ann. N. Y. Acad. Sci. 878, 713-715
29. Ogata, Y., Enghild, J. J., and Nagase, H. (1992) J. Biol. Chem. 267, 3581-3584
30. Ramos-DeSimone, N., Hahn-Dantona, E., Sipley, J., Nagase, H., French, D. L., and Quigley, J. P. (1999) J. Biol. Chem. 274, 13066-13076
31. Goldberg, G. I., Strongin, A., Collier, I. E., Genrich, L. T., and Marmer, B. L. (1992) J. Biol. Chem. 267, 4583-4591
32. Galardy, R. E., Cassabonne, M. E., Giese, C., Gilbert, J. H., Lapierre, F., Lopez, H., Schaeffer, M. E., Stack, R., Sullivan, M., Summers, B., Tressler, R., Tyrrell, D., Wee, J., Allen, S. D., Castellot, J. J., Barletta, J. P., Schultz, G. S., Fernandez, L. A., Fisher, S., Cui, T.-Y., Toellmer, H. G., Grobelny, D., and Holleran, W. M. (1994) Ann. N. Y. Acad. Sci. 732, 315-323
33. Deryugina, E. I., Bourdon, M. A., Reisfeld, R. A., and Strongin, A. (1998) Cancer Res. 58, 3743-3750
34. Ratnikov, B., Deryugina, E., Leng, J., Marchenko, G., Dembrow, D., and Strongin, A. (2000) Anal. Biochem. 286, 149-155
35. Shofuda, K., Moriyama, K., Nishihashi, A., Higashi, S., Mizushima, H., Yasumitsu, H., Miki, K., Sato, H., Seiki, M., and Miyazaki, K. (1998) J. Biochem. 124, 462-470
36. Yana, I., and Weiss, S. J. (2000) Mol. Biol. Cell 11, 2387-2401
37. Maquoi, E., Noel, A., Frankenne, F., Angliker, H., Murphy, G., and Foidart, J. M. (1998) FEBS Lett. 424, 262-266
38. Fernandez-Catalan, C., Bode, W., Huber, R., Turk, D., Calvete, J. J., Lichte, A., Tschesche, H., and Maskos, K. (1998) EMBO J. 17, 5238-5248
39. Steele, D. L., El-Kabbani, O., Dunten, P., Windsor, L. J., Kammlott, R. U., Crowther, R. L., Michoud, C., Engler, J. A., and Birktoft, J. J. (2000) Protein Eng. 13, 397-405
40. Valtanen, H., Lehti, K., Lohi, J., and Keski-Oja, J. (2000) Protein Expression Purif 19, 66-73
41. Holmbeck, K., Bianco, P., Caterina, J., Yamada, S., Kromer, M., Kuznetsov, S. A., Mankani, M., Robey, P. G., Poole, A. R., Pidoux, I., Ward, J. M., and Birkedal-Hansen, H. (1999) Cell 99, 81-92
42. Hiraoka, N., Allen, E., Apel, I. J., Gyetko, M. R., and Weiss, S. J. (1998) Cell 95, 365-377
43. Hotary, K., Allen, E., Punturieri, A., Yana, I., and Weiss, S. J. (2000) J. Cell Biol. 149, 1309-1323
44. Quaranta, V. (2000) J. Cell Biol. 149, 1167-1170
45. Nakahara, H., Howard, L., Thompson, E. W., Sato, H., Seiki, M., Yeh, Y., and Chen, W. T. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7959-7964
46. Chen, W. T., and Wang, J. Y. (1999) Ann. N. Y. Acad. Sci. 878, 361-371
47. Nabeshima, K., Inoue, T., Shimao, Y., Okada, Y., Itoh, Y., Seiki, M., and Koono, M. (2000) Cancer Res. 60, 3364-3369
48. Sato, T., del Carmen Ovejero, M., Hou, P., Heegaard, A. M., Kumegawa, M., Foged, N. T., and Delaisse, J. M. (1997) J. Cell Sci. 110, 589-596
49. Lehti, K., Lohi, J., Valtanen, H., and Keski-Oja, J. (1998) Biochem. J. 334, 345-353
50. Knauper, V., Will, H., Lopez-Otin, C., Smith, B., Atkinson, S. J., Stanton, H., Hembry, R. M., and Murphy, G. (1996) J. Biol. Chem. 271, 17124-17131
51. Caterina, J. J., Yamada, S., Caterina, N. C., Longenecker, G., Holmbäck, K., Shi, J., Yermovsky, A. E., Engler, J. A., and Birkedal-Hansen, H. (2000) J. Biol. Chem. 275, 26416-26422
52. Wang, Z., Juttermann, R., and Soloway, P. D. (2000) J. Biol. Chem. 275, 26411-26415
53. Kazes, I., Elalamy, I., Sraer, J. D., Hatmi, M., and Nguyen, G. (2000) Blood 96, 3064-3069
54. Llano, E., Pendas, A. M., Freije, J. P., Nakano, A., Knauper, V., Murphy, G., and Lopez-Otin, C. (1999) Cancer Res. 59, 2570-2576
55. Pei, D. (1999) Cell Res. 9, 291-303
56. Velasco, G., Cal, S., Merlos-Suarez, A., Ferrando, A. A., Alvarez, S., Nakano, A., Arribas, J., and Lopez-Otin, C. (2000) Cancer Res. 60, 877-882
57. Itoh, Y., Kajita, M., Kinoh, H., Mori, H., Okada, A., and Seiki, M. (1999) J. Biol. Chem. 274, 34260-34266
58. Ferrari, D. M., and Soling, H. D. (1999) Biochem. J. 339, 1-10
59. Stanton, H., Gavrilovic, J., Atkinson, S. J., d'Ortho, M. P., Yamada, K. M., Zardi, L., and Murphy, G. (1998) J. Cell Sci. 111, 2789-2798
60. Koshikawa, N., Giannelli, G., Cirulli, V., Miyazaki, K., and Quaranta, V. (2000) J. Cell Biol. 148, 615-624
61. Sato, T., Iwai, M., Sakai, T., Sato, H., Seiki, M., Mori, Y., and Ito, A. (1999) Br. J. Cancer 80, 1137-1143
62. Belien, A. T., Paganetti, P. A., and Schwab, M. E. (1999) J. Cell Biol. 144, 373-384
63. Xu, Z., Hirasawa, A., Shinoura, H., and Tsujimoto, G. (1999) J. Biol. Chem. 274, 21149-21154