Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr / mice

Journal of Hepatology

Volumn 62, Issue 2, 2015, Pages 430-436

  Hendrikx, Tim ^a   Jeurissen, Mike L J ^a   Bieghs, Veerle ^a   Walenbergh, Sofie M A ^a   Van Gorp, Patrick J ^a   Verheyen, Fons ^a   Houben, Tom ^a   Guichot, Yasmin Dias ^a   Gijbels, Marion J J ^a   Leitersdorf, Eran ^b   Hofker, Marten H ^c   Lütjohann, Dieter ^d   Shiri Sverdlov, Ronit ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

Cholesterol; CYP27A1; Kupffer cells

Indexed keywords

26 HYDROXYCHOLESTEROL; CARBOHYDRATE; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL; 27-HYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE; CYP27A1 PROTEIN, MOUSE; DNA; LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIETIC SYSTEM; HEPATITIS; HYPERLIPIDEMIA; KUPFFER CELL; LIVER LEVEL; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; BONE MARROW TRANSPLANTATION; C57BL MOUSE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PATHOLOGY;

ANIMALS; BONE MARROW TRANSPLANTATION; CHOLESTANETRIOL 26-MONOOXYGENASE; DISEASE MODELS, ANIMAL; DNA; GENE EXPRESSION REGULATION; HYDROXYCHOLESTEROLS; KUPFFER CELLS; LIPOPROTEINS, LDL; MALE; MICE; MICE, INBRED C57BL; NON-ALCOHOLIC FATTY LIVER DISEASE;

EID: 84922246659     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.09.027     Document Type: Article

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