메뉴 건너뛰기




Volumn 302, Issue 10, 2012, Pages

Macrophage-specific transgenic expression of cholesteryl ester hydrolase attenuates hepatic lipid accumulation and also improves glucose tolerance in ob/ob mice

Author keywords

Cell to cell interaction; Coculture; Macrophage phenotype and inflammatory status

Indexed keywords

CHOLESTEROL ESTER; CHOLESTEROL ESTERASE; LIPID; TRIACYLGLYCEROL;

EID: 84861116568     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00511.2011     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 77957956790 scopus 로고    scopus 로고
    • CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice
    • Aoyama T, Inokuchi S, Brenner DA, Seki E. CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. Hepatology 52: 1390-1400, 2010.
    • (2010) Hepatology , vol.52 , pp. 1390-1400
    • Aoyama, T.1    Inokuchi, S.2    Brenner, D.A.3    Seki, E.4
  • 2
    • 77957752986 scopus 로고    scopus 로고
    • Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus
    • Bagheri R, Qasim AN, Mehta NN, Terembula K, Kapoor S, Braunstein S, Schutta M, Iqbal N, Lehrke M, Reilly MP. Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus. Am J Cardiol 106: 1118-1123, 2010.
    • (2010) Am J Cardiol , vol.106 , pp. 1118-1123
    • Bagheri, R.1    Qasim, A.N.2    Mehta, N.N.3    Terembula, K.4    Kapoor, S.5    Braunstein, S.6    Schutta, M.7    Iqbal, N.8    Lehrke, M.9    Reilly, M.P.10
  • 3
    • 80053623971 scopus 로고    scopus 로고
    • Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic mice
    • Bie J, Zhao B, Ghosh S. Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic mice. Am J Physiol Regul Integr Comp Physiol 301: R967-R974, 2011.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.301
    • Bie, J.1    Zhao, B.2    Ghosh, S.3
  • 4
    • 77951603544 scopus 로고    scopus 로고
    • Improved insulin sensitivity in high fatand high cholesterol-fed Ldlr_/_ mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: Role of macrophage inflammation and infiltration into adipose tissue
    • Bie J, Zhao B, Song J, Ghosh S. Improved insulin sensitivity in high fatand high cholesterol-fed Ldlr_/_ mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue. J Biol Chem 285: 13630-13637, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 13630-13637
    • Bie, J.1    Zhao, B.2    Song, J.3    Ghosh, S.4
  • 5
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917, 1959.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 7
    • 79954613344 scopus 로고    scopus 로고
    • Polymorphisms in fatty acid binding protein 5 show association with type 2 diabetes
    • Bu L, Salto LM, De Leon KJ, De Leon M. Polymorphisms in fatty acid binding protein 5 show association with type 2 diabetes. Diabetes Res Clin Pract 92: 82-91, 2011.
    • (2011) Diabetes Res Clin Pract , vol.92 , pp. 82-91
    • Bu, L.1    Salto, L.M.2    de Leon, K.J.3    de Leon, M.4
  • 8
    • 0000279908 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and the risk for type 2 diabetes in the United States (Abstract)
    • Clark JM, Diehl AM, Brancati FL. Nonalcoholic fatty liver disease and the risk for type 2 diabetes in the United States (Abstract). Diabetes 50: A38, 2001.
    • (2001) Diabetes , vol.50
    • Clark, J.M.1    Diehl, A.M.2    Brancati, F.L.3
  • 9
    • 73349127065 scopus 로고    scopus 로고
    • Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling
    • Clementi AH, Gaudy AM, van Rooijen N, Pierce RH, Mooney RA. Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling. Biochim Biophys Acta 1792: 1062-1072, 2009.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 1062-1072
    • Clementi, A.H.1    Gaudy, A.M.2    van Rooijen, N.3    Pierce, R.H.4    Mooney, R.A.5
  • 10
    • 35348965856 scopus 로고    scopus 로고
    • Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice
    • Coenen KR, Gruen ML, Hasty AH. Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice. J Nutr Biochem 18: 727-735, 2007.
    • (2007) J Nutr Biochem , vol.18 , pp. 727-735
    • Coenen, K.R.1    Gruen, M.L.2    Hasty, A.H.3
  • 11
    • 77956395533 scopus 로고    scopus 로고
    • The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes
    • Cusi K. The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes. Curr Diab Rep 10: 306-315, 2010.
    • (2010) Curr Diab Rep , vol.10 , pp. 306-315
    • Cusi, K.1
  • 13
    • 0035913109 scopus 로고    scopus 로고
    • The inflamed plaque: Cytokine production and cellular cholesterol balance in the vessel wall
    • Fazio S, Linton MF. The inflamed plaque: cytokine production and cellular cholesterol balance in the vessel wall. Am J Cardiol 88: 12E-15E, 2001.
    • (2001) Am J Cardiol , vol.88
    • Fazio, S.1    Linton, M.F.2
  • 15
    • 77957371584 scopus 로고    scopus 로고
    • Insulin-and leptinregulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice
    • Ge F, Zhou S, Hu C, Lobdell H 4th, Berk PD. Insulin-and leptinregulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice. Am J Physiol Gastrointest Liver Physiol 299: G855-G866, 2010.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • Ge, F.1    Zhou, S.2    Hu, C.3    Lobdell I.V, H.4    Berk, P.D.5
  • 17
    • 77449117735 scopus 로고    scopus 로고
    • Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance
    • Huang W, Metlakunta A, Dedousis N, Zhang P, Sipula I, Dube JJ, Scott DK, O'Doherty RM. Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance. Diabetes 59: 347-357, 2010.
    • (2010) Diabetes , vol.59 , pp. 347-357
    • Huang, W.1    Metlakunta, A.2    Dedousis, N.3    Zhang, P.4    Sipula, I.5    Dube, J.J.6    Scott, D.K.7    O'Doherty, R.M.8
  • 18
    • 83655192012 scopus 로고    scopus 로고
    • Role of tissue macrophages in the development of critical illness diabetes
    • Jiang S, Gavrikova TA, Sharifov OF, Messina JL. Role of tissue macrophages in the development of critical illness diabetes. Shock 37: 70-76, 2012.
    • (2012) Shock , vol.37 , pp. 70-76
    • Jiang, S.1    Gavrikova, T.A.2    Sharifov, O.F.3    Messina, J.L.4
  • 19
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
    • Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, Lee CH. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab 7: 485-495, 2008.
    • (2008) Cell Metab , vol.7 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3    Gangl, M.R.4    Fitzgerald, K.5    Hatano, B.6    Lee, C.H.7
  • 22
    • 82655181355 scopus 로고    scopus 로고
    • Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet
    • Lanthier N, Molendi-Coste O, Cani PD, van Rooijen N, Horsmans Y, Leclercq IA. Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet. FASEB J 25: 4301-4311, 2011.
    • (2011) FASEB J , vol.25 , pp. 4301-4311
    • Lanthier, N.1    Molendi-Coste, O.2    Cani, P.D.3    van Rooijen, N.4    Horsmans, Y.5    Leclercq, I.A.6
  • 23
    • 52649158262 scopus 로고    scopus 로고
    • Ectopic fat and insulin resistance
    • Lettner A, Roden M. Ectopic fat and insulin resistance. Curr Diab Rep 8: 185-191, 2008.
    • (2008) Curr Diab Rep , vol.8 , pp. 185-191
    • Lettner, A.1    Roden, M.2
  • 25
  • 27
    • 0033047434 scopus 로고    scopus 로고
    • Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes
    • Milosevic N, Schawalder H, Maier P. Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes. Eur J Pharmacol 368: 75-87, 1999.
    • (1999) Eur J Pharmacol , vol.368 , pp. 75-87
    • Milosevic, N.1    Schawalder, H.2    Maier, P.3
  • 29
    • 0036110273 scopus 로고    scopus 로고
    • Inhibition of Kupffer cell activity induces hepatic triglyceride synthesis in fasted rats, independent of lipopolysaccharide challenge
    • Neyrinck AM, Taper HS, Gevers V, Declerck B, Delzenne NM. Inhibition of Kupffer cell activity induces hepatic triglyceride synthesis in fasted rats, independent of lipopolysaccharide challenge. J Hepatol 36: 466-473, 2002.
    • (2002) J Hepatol , vol.36 , pp. 466-473
    • Neyrinck, A.M.1    Taper, H.S.2    Gevers, V.3    Declerck, B.4    Delzenne, N.M.5
  • 31
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 72: 219-246, 2010.
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 32
    • 0034490479 scopus 로고    scopus 로고
    • A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes
    • Park JS, Qiao L, Gilfor D, Yang MY, Hylemon PB, Benz C, Darlington G, Firestone G, Fisher PB, Dent P. A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes. Mol Biol Cell 11: 2915-2932, 2000.
    • (2000) Mol Biol Cell , vol.11 , pp. 2915-2932
    • Park, J.S.1    Qiao, L.2    Gilfor, D.3    Yang, M.Y.4    Hylemon, P.B.5    Benz, C.6    Darlington, G.7    Firestone, G.8    Fisher, P.B.9    Dent, P.10
  • 35
    • 17644419944 scopus 로고    scopus 로고
    • Hepatocytes enhance effects of lipopolysaccharide on liver nonparenchymal cells through close cell interactions
    • Scott MJ, Liu S, Su GL, Vodovotz Y, Billiar TR. Hepatocytes enhance effects of lipopolysaccharide on liver nonparenchymal cells through close cell interactions. Shock 23: 453-458, 2005.
    • (2005) Shock , vol.23 , pp. 453-458
    • Scott, M.J.1    Liu, S.2    Su, G.L.3    Vodovotz, Y.4    Billiar, T.R.5
  • 37
    • 42949116365 scopus 로고    scopus 로고
    • Lipid accumulation in non-adipose tissue and lipotoxicity
    • van Herpen NA, Schrauwen-Hinderling VB. Lipid accumulation in non-adipose tissue and lipotoxicity. Physiol Behav 94: 231-241, 2008.
    • (2008) Physiol Behav , vol.94 , pp. 231-241
    • van Herpen, N.A.1    Schrauwen-Hinderling, V.B.2
  • 38
    • 2442588927 scopus 로고    scopus 로고
    • Kupffer cell cytokines interleukin-1beta and interleukin-10 combine to inhibit phosphoenolpyruvate carboxykinase and gluconeogenesis in cultured hepatocytes
    • Yerkovich ST, Rigby PJ, Fournier PA, Olynyk JK, Yeoh GC. Kupffer cell cytokines interleukin-1beta and interleukin-10 combine to inhibit phosphoenolpyruvate carboxykinase and gluconeogenesis in cultured hepatocytes. Int J Biochem Cell Biol 36: 1462-1472, 2004.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1462-1472
    • Yerkovich, S.T.1    Rigby, P.J.2    Fournier, P.A.3    Olynyk, J.K.4    Yeoh, G.C.5
  • 39
    • 34948878197 scopus 로고    scopus 로고
    • Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice
    • Zhao B, Song J, Chow WN, St Clair RW, Rudel LL, Ghosh S. Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice. J Clin Invest 117: 2983-2992, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 2983-2992
    • Zhao, B.1    Song, J.2    Chow, W.N.3    St Clair, R.W.4    Rudel, L.L.5    Ghosh, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.