NO-1886 Up-regulates Niemann-Pick C1 protein (NPC1) expression through liver X receptor α signaling pathway in THP-1 macrophage-derived foam cells

Cardiovascular Drugs and Therapy

Volumn 23, Issue 3, 2009, Pages 199-206

  Ma, Xin ^a,b   Hu, Yan Wei ^a   Mo, Zhong Cheng ^a   Li, Xiao Xu ^a   Liu, Xie Hong ^a   Xiao, Ji ^a   Yin, Wei Dong ^a   Liao, Duan Fang ^a   Tang, Chao Ke ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b THE FIRST AFFILIATED HOSPITAL OF UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Atherosclerosis; Cholesterol; LXR ; NO 1886; NPC1

Indexed keywords

4 [(4 BROMO 2 CYANOPHENYL)CARBAMOYL]BENZYLPHOSPHONIC ACID DIETHYL ESTER; CHOLESTEROL; LIVER X RECEPTOR ALPHA; MEMBRANE PROTEIN; MEMBRANE PROTEIN NPC1; MESSENGER RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; FOAM CELL; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

ANTILIPEMIC AGENTS; BENZAMIDES; CARRIER PROTEINS; CELL LINE; CHOLESTEROL; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FOAM CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; ORGANOPHOSPHORUS COMPOUNDS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION;

EID: 67649090227     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-009-6165-8     Document Type: Article

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