-
1
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck P. K., Chan H. Y., Trojanowski J. Q., Lee V. M., and, Bonini N. M., (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295, 865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
2
-
-
13244267202
-
Mechanisms of suppression of {alpha}-synuclein neurotoxicity by geldanamycin in drosophila
-
Auluck P. K., Meulener M. C., and, Bonini N. M., (2005) Mechanisms of suppression of {alpha}-synuclein neurotoxicity by geldanamycin in drosophila. J. Biol. Chem. 280, 2873-2878.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2873-2878
-
-
Auluck, P.K.1
Meulener, M.C.2
Bonini, N.M.3
-
3
-
-
0033782266
-
GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila
-
Barolo S., Carver L. A., and, Posakony J. W., (2000) GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila. Biotechniques 29, 726-732.
-
(2000)
Biotechniques
, vol.29
, pp. 726-732
-
-
Barolo, S.1
Carver, L.A.2
Posakony, J.W.3
-
4
-
-
80052277569
-
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease
-
Barone M. C., Sykiotis G. P., and, Bohmann D., (2011) Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. Dis. Model. Mech. 4, 701-707.
-
(2011)
Dis. Model. Mech.
, vol.4
, pp. 701-707
-
-
Barone, M.C.1
Sykiotis, G.P.2
Bohmann, D.3
-
5
-
-
77955846091
-
Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease
-
Bayersdorfer F., Voigt A., Schneuwly S., and, Botella J. A., (2010) Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease. Neurobiol. Dis. 40, 113-119.
-
(2010)
Neurobiol. Dis.
, vol.40
, pp. 113-119
-
-
Bayersdorfer, F.1
Voigt, A.2
Schneuwly, S.3
Botella, J.A.4
-
6
-
-
40849130108
-
Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease
-
Botella J. A., Bayersdorfer F., and, Schneuwly S., (2008) Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease. Neurobiol. Dis. 30, 65-73.
-
(2008)
Neurobiol. Dis.
, vol.30
, pp. 65-73
-
-
Botella, J.A.1
Bayersdorfer, F.2
Schneuwly, S.3
-
7
-
-
72949108454
-
Modelling Parkinson's disease in Drosophila
-
Botella J. A., Bayersdorfer F., Gmeiner F., and, Schneuwly S., (2009) Modelling Parkinson's disease in Drosophila. Neuromolecular Med. 11, 268-280.
-
(2009)
Neuromolecular Med.
, vol.11
, pp. 268-280
-
-
Botella, J.A.1
Bayersdorfer, F.2
Gmeiner, F.3
Schneuwly, S.4
-
8
-
-
26844505808
-
Toxin-induced models of Parkinson's disease
-
Boyé J., Prou D., Perier C., and, Przedborski S., (2005) Toxin-induced models of Parkinson's disease. NeuroRx. 2, 484-494.
-
(2005)
NeuroRx.
, vol.2
, pp. 484-494
-
-
Boyé, J.1
Prou, D.2
Perier, C.3
Przedborski, S.4
-
9
-
-
84871461174
-
Layered reward signalling through octopamine and dopamine in Drosophila
-
Burke C. J., Huetteroth W., Owald D., Perisse E., Krashes M. J., Das G., Gohl D., Silies M., Certel S., and, Waddell S., (2012) Layered reward signalling through octopamine and dopamine in Drosophila. Nature 492, 433-437.
-
(2012)
Nature
, vol.492
, pp. 433-437
-
-
Burke, C.J.1
Huetteroth, W.2
Owald, D.3
Perisse, E.4
Krashes, M.J.5
Das, G.6
Gohl, D.7
Silies, M.8
Certel, S.9
Waddell, S.10
-
10
-
-
22544458436
-
Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila
-
Cha G. H., Kim S., Park J., Lee E., Kim M., Lee S. B., Kim J. M., Chung J., and, Cho K. S., (2005) Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc. Natl. Acad. Sci. USA 102, 10345-10350.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 10345-10350
-
-
Cha, G.H.1
Kim, S.2
Park, J.3
Lee, E.4
Kim, M.5
Lee, S.B.6
Kim, J.M.7
Chung, J.8
Cho, K.S.9
-
11
-
-
33847769245
-
Interaction of genetic and environmental factors in a Drosophila parkinsonism model
-
Chaudhuri A., Bowling K., Funderburk C., Lawal H., Inamdar A., Wang Z., and, O'Donnell J. M., (2007) Interaction of genetic and environmental factors in a Drosophila parkinsonism model. J. Neurosci. 27, 2457-2467.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2457-2467
-
-
Chaudhuri, A.1
Bowling, K.2
Funderburk, C.3
Lawal, H.4
Inamdar, A.5
Wang, Z.6
O'Donnell, J.M.7
-
12
-
-
17844406856
-
Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
-
Chen L., and, Feany M. B., (2005) Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat. Neurosci. 8, 657-663.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 657-663
-
-
Chen, L.1
Feany, M.B.2
-
13
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark I. E., Dodson M. W., Jiang C., Cao J. H., Huh J. R., Seol J. H., Yoo S. J., Hay B. A., and, Guo M., (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441, 1162-1166.
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
14
-
-
33746533924
-
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper A. A., Gitler A. D., Cashikar A., et al,. (2006) Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 313, 324-328.
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
-
15
-
-
10044292870
-
Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster
-
Coulom H., and, Birman S., (2004) Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. J. Neurosci. 24, 10993-10998.
-
(2004)
J. Neurosci.
, vol.24
, pp. 10993-10998
-
-
Coulom, H.1
Birman, S.2
-
16
-
-
34447530305
-
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
-
Dietzl G., Chen D., Schnorrer F., et al,. (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448, 151-156.
-
(2007)
Nature
, vol.448
, pp. 151-156
-
-
Dietzl, G.1
Chen, D.2
Schnorrer, F.3
-
17
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany M. B., and, Bender W. W., (2000) A Drosophila model of Parkinson's disease. Nature 404, 394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
18
-
-
0037370716
-
Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase
-
Friggi-Grelin F., Coulom H., Meller M., Gomez D., Hirsh J., and, Birman S., (2003) Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase. J. Neurobiol. 54, 618-627.
-
(2003)
J. Neurobiol.
, vol.54
, pp. 618-627
-
-
Friggi-Grelin, F.1
Coulom, H.2
Meller, M.3
Gomez, D.4
Hirsh, J.5
Birman, S.6
-
19
-
-
79956014439
-
Synphilin suppresses α-synuclein neurotoxicity in a Parkinson's disease Drosophila model
-
Hernández-Vargas R., Fonseca-Ornelas L., Lõpez-González I., Riesgo-Escovar J., Zurita M., and, Reynaud E., (2011) Synphilin suppresses α-synuclein neurotoxicity in a Parkinson's disease Drosophila model. Genesis 49, 392-402.
-
(2011)
Genesis
, vol.49
, pp. 392-402
-
-
Hernández-Vargas, R.1
Fonseca-Ornelas, L.2
Lõpez-González, I.3
Riesgo-Escovar, J.4
Zurita, M.5
Reynaud, E.6
-
20
-
-
84863137295
-
Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease
-
Kim K., Kim S. H., Ki J., Kim H., and, Yim J., (2012) Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease. J. Biol. Chem. 287, 6628-6641.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 6628-6641
-
-
Kim, K.1
Kim, S.H.2
Ki, J.3
Kim, H.4
Yim, J.5
-
21
-
-
77955846610
-
The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons
-
Lawal H. O., Chang H. Y., Terrell A. N., Brooks E. S., Pulido D., Simon A. F., and, Krantz D. E., (2010) The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons. Neurobiol. Dis. 40, 102-112.
-
(2010)
Neurobiol. Dis.
, vol.40
, pp. 102-112
-
-
Lawal, H.O.1
Chang, H.Y.2
Terrell, A.N.3
Brooks, E.S.4
Pulido, D.5
Simon, A.F.6
Krantz, D.E.7
-
22
-
-
70349800685
-
Eight different types of dopaminergic neurons innervate the Drosophila mushroom body neuropil: Anatomical and physiological heterogeneity
-
Mao Z., and, Davis R. L., (2009) Eight different types of dopaminergic neurons innervate the Drosophila mushroom body neuropil: anatomical and physiological heterogeneity. Front. Neural Circuits 3, 5.
-
(2009)
Front. Neural Circuits
, vol.3
, pp. 5
-
-
Mao, Z.1
Davis, R.L.2
-
23
-
-
24044472010
-
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
-
Meulener M., Whitworth A. J., Armstrong-Gold C. E., Rizzu P., Heutink P., Wes P. D., Pallanck L. J., and, Bonini N. M., (2005) Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr. Biol. 15, 1572-1577.
-
(2005)
Curr. Biol.
, vol.15
, pp. 1572-1577
-
-
Meulener, M.1
Whitworth, A.J.2
Armstrong-Gold, C.E.3
Rizzu, P.4
Heutink, P.5
Wes, P.D.6
Pallanck, L.J.7
Bonini, N.M.8
-
24
-
-
0026790115
-
Aminergic neurons in the brain of blowfliesand Drosophila: Dopamine- and tyrosine hydroxylase-immunoreactive neurons and their relationship with putative histaminergic neurons
-
Nässel D. R., and, Elekes K., (1992) Aminergic neurons in the brain of blowfliesand Drosophila: dopamine- and tyrosine hydroxylase-immunoreactive neurons and their relationship with putative histaminergic neurons. Cell Tissue Res. 267, 147-167.
-
(1992)
Cell Tissue Res.
, vol.267
, pp. 147-167
-
-
Nässel, D.R.1
Elekes, K.2
-
25
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J., Lee S. B., Lee S., et al,. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441, 1157-116113.
-
(2006)
Nature
, vol.441
, pp. 1157-116113
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
-
26
-
-
36248929304
-
Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein
-
Park S. S., Schulz E. M., and, Lee D., (2007) Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein. Eur. J. Neurosci. 26, 3104-3112.
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 3104-3112
-
-
Park, S.S.1
Schulz, E.M.2
Lee, D.3
-
27
-
-
2542560342
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
-
Pesah Y., Pham T., Burgess H., Middlebrooks B., Verstreken P., Zhou Y., Harding M., Bellen H., and, Mardon G., (2004) Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 131, 2183-2194.
-
(2004)
Development
, vol.131
, pp. 2183-2194
-
-
Pesah, Y.1
Pham, T.2
Burgess, H.3
Middlebrooks, B.4
Verstreken, P.5
Zhou, Y.6
Harding, M.7
Bellen, H.8
Mardon, G.9
-
28
-
-
18544362489
-
Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of alpha-Synuclein in Drosophila
-
Pesah Y., Burgess H., Middlebrooks B., Ronningen K., Prosser J., Tirunagaru V., Zysk J., and, Mardon G., (2005) Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of alpha-Synuclein in Drosophila. Genesis 41, 154-159.
-
(2005)
Genesis
, vol.41
, pp. 154-159
-
-
Pesah, Y.1
Burgess, H.2
Middlebrooks, B.3
Ronningen, K.4
Prosser, J.5
Tirunagaru, V.6
Zysk, J.7
Mardon, G.8
-
29
-
-
38349014710
-
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease
-
Trinh K., Moore K., Wes P. D., Muchowski P. J., Dey J., Andrews L., and, Pallanck L. J., (2008) Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J. Neurosci. 28, 465-472.
-
(2008)
J. Neurosci.
, vol.28
, pp. 465-472
-
-
Trinh, K.1
Moore, K.2
Wes, P.D.3
Muchowski, P.J.4
Dey, J.5
Andrews, L.6
Pallanck, L.J.7
-
30
-
-
77951543964
-
Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism
-
Trinh K., Andrews L., Krause J., Hanak T., Lee D., Gelb M., and, Pallanck L., (2010) Decaffeinated coffee and nicotine-free tobacco provide neuroprotection in Drosophila models of Parkinson's disease through an NRF2-dependent mechanism. J. Neurosci. 30, 5525-5532.
-
(2010)
J. Neurosci.
, vol.30
, pp. 5525-5532
-
-
Trinh, K.1
Andrews, L.2
Krause, J.3
Hanak, T.4
Lee, D.5
Gelb, M.6
Pallanck, L.7
-
31
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente E. M., Abou-Sleiman P. M., Caputo V., et al,. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304, 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
-
32
-
-
33748600694
-
Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila
-
Wang D., Qian L., Xiong H., Liu J., Neckameyer W.S., Oldham S., Xia K., Wang J., Bodmer R., and, Zhang Z., (2006) Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila. Proc. Natl. Acad. Sci. USA 103, 13520-13525.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13520-13525
-
-
Wang, D.1
Qian, L.2
Xiong, H.3
Liu, J.4
Neckameyer, W.S.5
Oldham, S.6
Xia, K.7
Wang, J.8
Bodmer, R.9
Zhang, Z.10
-
33
-
-
34547885021
-
Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities
-
Wang C., Lu R., Ouyang X., Ho M. W., Chia W., Yu F., and, Lim K. L., (2007) Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities. J. Neurosci. 27, 8563-8570.
-
(2007)
J. Neurosci.
, vol.27
, pp. 8563-8570
-
-
Wang, C.1
Lu, R.2
Ouyang, X.3
Ho, M.W.4
Chia, W.5
Yu, F.6
Lim, K.L.7
-
34
-
-
84891730000
-
The dopaminergic system in the aging brain of Drosophila
-
White K. E., Humphrey D. M., and, Hirth F., (2010) The dopaminergic system in the aging brain of Drosophila. Front Neurosci. 4, 205.
-
(2010)
Front Neurosci.
, vol.4
, pp. 205
-
-
White, K.E.1
Humphrey, D.M.2
Hirth, F.3
-
35
-
-
79551648939
-
Drosophila models of Parkinson's disease
-
Whitworth A. J., (2011) Drosophila models of Parkinson's disease. Adv. Genet. 73, 1-50.
-
(2011)
Adv. Genet.
, vol.73
, pp. 1-50
-
-
Whitworth, A.J.1
-
36
-
-
20344369560
-
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
-
Whitworth A. J., Theodore D. A., Greene J. C., Benes H., Wes P. D., and, Pallanck L. J., (2005) Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 102, 8024-8029.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8024-8029
-
-
Whitworth, A.J.1
Theodore, D.A.2
Greene, J.C.3
Benes, H.4
Wes, P.D.5
Pallanck, L.J.6
-
37
-
-
33644862373
-
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease
-
Whitworth A. J., Wes P. D., and, Pallanck L. J., (2006) Drosophila models pioneer a new approach to drug discovery for Parkinson's disease. Drug Discov. Today 11, 119-126.
-
(2006)
Drug Discov. Today
, vol.11
, pp. 119-126
-
-
Whitworth, A.J.1
Wes, P.D.2
Pallanck, L.J.3
-
38
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
Yang Y., Gehrke S., Imai Y., Huang Z., Ouyang Y., Wang J. W., Yang L., Beal M. F., Vogel H., and, Lu B., (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl. Acad. Sci. USA 103, 10793-10798.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
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