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Volumn 3, Issue November, 2014, Pages 1-23

RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; BETA3 INTEGRIN; CD24 ANTIGEN; ESTROGEN RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; PROTEIN P53; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR RUNX1; CITED1 PROTEIN, MOUSE; CRE RECOMBINASE; DNA BINDING PROTEIN; ELF5 PROTEIN, MOUSE; FOXA1 PROTEIN, MOUSE; INTEGRASE; NUCLEAR PROTEIN; RETINOBLASTOMA PROTEIN; RUNX1 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 84922157157     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.03881     Document Type: Article
Times cited : (89)

References (65)
  • 7
    • 0035066381 scopus 로고    scopus 로고
    • The leukemia-associated AML1 (Runx1)-CBF beta complex functions as a DNA-induced molecular clamp
    • Bravo J, Li Z, Speck NA, Warren AJ. 2001. The leukemia-associated AML1 (Runx1)-CBF beta complex functions as a DNA-induced molecular clamp. Nature Structural Biology 8:371-378. doi: 10.1038/86264.
    • (2001) Nature Structural Biology , vol.8 , pp. 371-378
    • Bravo, J.1    Li, Z.2    Speck, N.A.3    Warren, A.J.4
  • 8
    • 84882958819 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. 2012. Comprehensive molecular portraits of human breast tumours. Nature 490:61-70. doi: 10.1038/nature11453.
    • (2012) Nature , vol.490 , pp. 61-70
  • 11
    • 84856523566 scopus 로고    scopus 로고
    • Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: In vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness
    • Chimge NO, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B. 2012. Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Clinical Cancer Research 18:901-911. doi: 10.1158/ 1078-0432.CCR-11-1530.
    • (2012) Clinical Cancer Research , vol.18 , pp. 901-911
    • Chimge, N.O.1    Baniwal, S.K.2    Luo, J.3    Coetzee, S.4    Khalid, O.5    Berman, B.P.6    Tripathy, D.7    Ellis, M.J.8    Frenkel, B.9
  • 12
    • 84876923776 scopus 로고    scopus 로고
    • The RUNX family in breast cancer: Relationships with estrogen signaling
    • Chimge NO, Frenkel B. 2013. The RUNX family in breast cancer: relationships with estrogen signaling. Oncogene 32:2121-2130. doi: 10.1038/onc.2012.328.
    • (2013) Oncogene , vol.32 , pp. 2121-2130
    • Chimge, N.O.1    Frenkel, B.2
  • 13
    • 67349124434 scopus 로고    scopus 로고
    • Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: Failure of Stat5 activation and functional differentiation in the absence of Elf5
    • Choi YS, Chakrabarti R, Escamilla-Hernandez R, Sinha S. 2009. Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5. Developmental Biology 329:227-241. doi: 10.1016/j.ydbio.2009.02.032.
    • (2009) Developmental Biology , vol.329 , pp. 227-241
    • Choi, Y.S.1    Chakrabarti, R.2    Escamilla-Hernandez, R.3    Sinha, S.4
  • 18
    • 79960119034 scopus 로고    scopus 로고
    • Myoepithelial cell contraction and milk ejection are impaired in mammary glands of mice lacking smooth muscle alpha-actin
    • Haaksma CJ, Schwartz RJ, Tomasek JJ. 2011. Myoepithelial cell contraction and milk ejection are impaired in mammary glands of mice lacking smooth muscle alpha-actin. Biology of Reproduction 85:13-21. doi: 10.1095/ biolreprod.110.090639.
    • (2011) Biology of Reproduction , vol.85 , pp. 13-21
    • Haaksma, C.J.1    Schwartz, R.J.2    Tomasek, J.J.3
  • 20
    • 33644844822 scopus 로고    scopus 로고
    • CITED1 homozygous null mice display aberrant pubertal mammary ductal morphogenesis
    • Howlin J, McBryan J, Napoletano S, Lambe T, McArdle E, Shioda T, Martin F. 2006. CITED1 homozygous null mice display aberrant pubertal mammary ductal morphogenesis. Oncogene 25:1532-1542. doi: 10.1038/sj.onc.1209183.
    • (2006) Oncogene , vol.25 , pp. 1532-1542
    • Howlin, J.1    McBryan, J.2    Napoletano, S.3    Lambe, T.4    McArdle, E.5    Shioda, T.6    Martin, F.7
  • 22
    • 34248199004 scopus 로고    scopus 로고
    • Bifurcation dynamics in lineage-commitment in bipotent progenitor cells
    • Huang S, Guo YP, May G, Enver T. 2007. Bifurcation dynamics in lineage-commitment in bipotent progenitor cells. Developmental Biology 305:695-713. doi: 10.1016/j.ydbio.2007.02.036.
    • (2007) Developmental Biology , vol.305 , pp. 695-713
    • Huang, S.1    Guo, Y.P.2    May, G.3    Enver, T.4
  • 23
    • 78651250284 scopus 로고    scopus 로고
    • FOXA1 is a key determinant of estrogen receptor function and endocrine response
    • Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS. 2011. FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nature Genetics 43:27-33. doi: 10.1038/ng.730.
    • (2011) Nature Genetics , vol.43 , pp. 27-33
    • Hurtado, A.1    Holmes, K.A.2    Ross-Innes, C.S.3    Schmidt, D.4    Carroll, J.S.5
  • 24
    • 10244279259 scopus 로고    scopus 로고
    • Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli
    • Jones FE, Jerry DJ, Guarino BC, Andrews GC, Stern DF. 1996. Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli. Cell Growth & Differentiation 7:1031-1038.
    • (1996) Cell Growth & Differentiation , vol.7 , pp. 1031-1038
    • Jones, F.E.1    Jerry, D.J.2    Guarino, B.C.3    Andrews, G.C.4    Stern, D.F.5
  • 27
    • 33751202983 scopus 로고    scopus 로고
    • GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland
    • Kouros-Mehr H, Slorach EM, Sternlicht MD, Werb Z. 2006. GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell 127:1041-1055. doi: 10.1016/j.cell.2006.09.048.
    • (2006) Cell , vol.127 , pp. 1041-1055
    • Kouros-Mehr, H.1    Slorach, E.M.2    Sternlicht, M.D.3    Werb, Z.4
  • 28
    • 33745170559 scopus 로고    scopus 로고
    • Requirement of a myocardin-related transcription factor for development of mammary myoepithelial cells
    • Li S, Chang S, Qi X, Richardson JA, Olson EN. 2006a. Requirement of a myocardin-related transcription factor for development of mammary myoepithelial cells. Molecular and Cellular Biology 26:5797-5808. doi: 10.1128/ MCB.00211-06.
    • (2006) Molecular and Cellular Biology , vol.26 , pp. 5797-5808
    • Li, S.1    Chang, S.2    Qi, X.3    Richardson, J.A.4    Olson, E.N.5
  • 30
    • 30144434921 scopus 로고    scopus 로고
    • Runx1 function in hematopoiesis is required in cells that express Tek
    • Li Z, Chen MJ, Stacy T, Speck NA. 2006b. Runx1 function in hematopoiesis is required in cells that express Tek. Blood 107:106-110. doi: 10.1182/blood-2005-05-1955.
    • (2006) Blood , vol.107 , pp. 106-110
    • Li, Z.1    Chen, M.J.2    Stacy, T.3    Speck, N.A.4
  • 38
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. 1996. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84:321-330. doi: 10.1016/S0092-8674(00)80986-1.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 40
    • 77953818935 scopus 로고    scopus 로고
    • Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged
    • Plante I, Wallis A, Shao Q, Laird DW. 2010. Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. Biology of Reproduction 82:837-847. doi: 10.1095/biolreprod.109.081406.
    • (2010) Biology of Reproduction , vol.82 , pp. 837-847
    • Plante, I.1    Wallis, A.2    Shao, Q.3    Laird, D.W.4
  • 43
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, Ross KN, Lander ES, Golub TR. 2003. A molecular signature of metastasis in primary solid tumors. Nature Genetics 33:49-54. doi: 10.1038/ng1060.
    • (2003) Nature Genetics , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 44
    • 84894267586 scopus 로고    scopus 로고
    • In situ identification of bipotent stem cells in the mammary gland
    • Rios AC, Fu NY, Lindeman GJ, Visvader JE. 2014. In situ identification of bipotent stem cells in the mammary gland. Nature 506:322-327. doi: 10.1038/nature12948.
    • (2014) Nature , vol.506 , pp. 322-327
    • Rios, A.C.1    Fu, N.Y.2    Lindeman, G.J.3    Visvader, J.E.4
  • 45
    • 0033731641 scopus 로고    scopus 로고
    • Rapid development of tamoxifen-stimulated mutant p53 breast tumors (T47D) in athymic mice
    • Schafer JM, Lee ES, O'Regan RM, Yao K, Jordan VC. 2000. Rapid development of tamoxifen-stimulated mutant p53 breast tumors (T47D) in athymic mice. Clinical Cancer Research 6:4373-4380.
    • (2000) Clinical Cancer Research , vol.6 , pp. 4373-4380
    • Schafer, J.M.1    Lee, E.S.2    O'Regan, R.M.3    Yao, K.4    Jordan, V.C.5
  • 46
    • 84875157758 scopus 로고    scopus 로고
    • New insights into the role of Runx1 in epithelial stem cell biology and pathology
    • Scheitz CJ, Tumbar T. 2013. New insights into the role of Runx1 in epithelial stem cell biology and pathology. Journal of Cellular Biochemistry 114:985-993. doi: 10.1002/jcb.24453.
    • (2013) Journal of Cellular Biochemistry , vol.114 , pp. 985-993
    • Scheitz, C.J.1    Tumbar, T.2
  • 50
    • 0036636857 scopus 로고    scopus 로고
    • Core-binding factors in haematopoiesis and leukaemia
    • Speck NA, Gilliland DG. 2002. Core-binding factors in haematopoiesis and leukaemia. Nature Reviews Cancer 2:502-513. doi: 10.1038/nrc840.
    • (2002) Nature Reviews Cancer , vol.2 , pp. 502-513
    • Speck, N.A.1    Gilliland, D.G.2
  • 51
    • 84863012487 scopus 로고    scopus 로고
    • A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer
    • Spike BT, Engle DD, Lin JC, Cheung SK, La J, Wahl GM. 2012. A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer. Cell Stem Cell 10:183-197. doi: 10.1016/j.stem.2011.12.018.
    • (2012) Cell Stem Cell , vol.10 , pp. 183-197
    • Spike, B.T.1    Engle, D.D.2    Lin, J.C.3    Cheung, S.K.4    La, J.5    Wahl, G.M.6
  • 52
    • 77955629953 scopus 로고    scopus 로고
    • Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation
    • Stender JD, Kim K, Charn TH, Komm B, Chang KC, Kraus WL, Benner C, Glass CK, Katzenellenbogen BS. 2010. Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Molecular and Cellular Biology 30:3943-3955. doi: 10.1128/MCB.00118-10.
    • (2010) Molecular and Cellular Biology , vol.30 , pp. 3943-3955
    • Stender, J.D.1    Kim, K.2    Charn, T.H.3    Komm, B.4    Chang, K.C.5    Kraus, W.L.6    Benner, C.7    Glass, C.K.8    Katzenellenbogen, B.S.9
  • 56
    • 84868597429 scopus 로고    scopus 로고
    • Runx1: No longer just for leukemia
    • Taniuchi I, Osato M, Ito Y. 2012. Runx1: no longer just for leukemia. The EMBO Journal 31:4098-4099. doi: 10.1038/emboj.2012.282.
    • (2012) The EMBO Journal , vol.31 , pp. 4098-4099
    • Taniuchi, I.1    Osato, M.2    Ito, Y.3
  • 57
    • 84902248072 scopus 로고    scopus 로고
    • Lineage tracing of mammary epithelial cells using cell-type-specific cre-expressing adenoviruses
    • Tao L, van Bragt MPA, Laudadio E, Li Z. 2014. Lineage tracing of mammary epithelial cells using cell-type-specific cre-expressing adenoviruses. Stem Cell Reports 2:770-779. doi: 10.1016/j.stemcr.2014.04.004.
    • (2014) Stem Cell Reports , vol.2 , pp. 770-779
    • Tao, L.1    van Bragt, M.P.A.2    Laudadio, E.3    Li, Z.4
  • 58
    • 84866114887 scopus 로고    scopus 로고
    • Developmental stage and time dictate the fate of Wnt/ beta-catenin-responsive stem cells in the mammary gland
    • van Amerongen R, Bowman AN, Nusse R. 2012. Developmental stage and time dictate the fate of Wnt/ beta-catenin-responsive stem cells in the mammary gland. Cell Stem Cell 11:387-400. doi: 10.1016/j. stem.2012.05.023.
    • (2012) Cell Stem Cell , vol.11 , pp. 387-400
    • van Amerongen, R.1    Bowman, A.N.2    Nusse, R.3
  • 62
    • 84922129231 scopus 로고    scopus 로고
    • Identification of multipotent mammary stem cells by protein C receptor expression
    • Wang D, Cai C, Dong X, Yu QC, Zhang XO, Yang L, Zeng YA. 2014. Identification of multipotent mammary stem cells by protein C receptor expression. Nature. doi: 10.1038/nature13851.
    • (2014) Nature
    • Wang, D.1    Cai, C.2    Dong, X.3    Yu, Q.C.4    Zhang, X.O.5    Yang, L.6    Zeng, Y.A.7
  • 64
    • 84857034150 scopus 로고    scopus 로고
    • Smooth muscle alpha actin is specifically required for the maintenance of lactation
    • Weymouth N, Shi Z, Rockey DC. 2012. Smooth muscle alpha actin is specifically required for the maintenance of lactation. Developmental Biology 363:1-14. doi: 10.1016/j.ydbio.2011.11.002.
    • (2012) Developmental Biology , vol.363 , pp. 1-14
    • Weymouth, N.1    Shi, Z.2    Rockey, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.