Increased glutamine catabolism mediates bone anabolism in response to WNT signaling

Journal of Clinical Investigation

Volumn 125, Issue 2, 2015, Pages 551-562

  Karner, Courtney M ^a   Esen, Emel ^a   Okunade, Adewole L ^a   Patterson, Bruce W ^a   Long, Fanxin ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GLUTAMINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; TRANSFER RNA; TRICARBOXYLIC ACID; WNT3A PROTEIN; AMINOACYL TRANSFER RNA; EIF2AK4 PROTEIN, HUMAN; EIF2AK4 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PROTEIN SERINE THREONINE KINASE; TARGET OF RAPAMYCIN KINASE;

AMINOACYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE ANABOLISM; BONE METABOLISM; CELL DIFFERENTIATION; CITRIC ACID CYCLE; CONTROLLED STUDY; FEMALE; GCN2 GENE; GENE; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; HUMAN; INTEGRATED STRESS RESPONSE; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOSCLEROSIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; STRESS; TRANSCRIPTION INITIATION; UPREGULATION; WNT SIGNALING PATHWAY; ANIMAL; BONE DEVELOPMENT; CELL LINE; GENETICS; METABOLISM; PATHOLOGY;

ANIMALS; CELL LINE; CITRIC ACID CYCLE; GENE DELETION; GLUTAMINE; HUMANS; MICE; MULTIPROTEIN COMPLEXES; OSTEOBLASTS; OSTEOGENESIS; OSTEOSCLEROSIS; PROTEIN-SERINE-THREONINE KINASES; RNA, TRANSFER, AMINO ACYL; TOR SERINE-THREONINE KINASES; WNT SIGNALING PATHWAY;

EID: 84922147373     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI78470     Document Type: Article

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