메뉴 건너뛰기




Volumn 125, Issue 2, 2015, Pages 495-497

In vivo analysis of lung cancer metabolism: Nothing like the real thing

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; GLUCOSE; PYRUVATE CARBOXYLASE; TUMOR PROTEIN;

EID: 84922130204     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI79188     Document Type: Review
Times cited : (17)

References (18)
  • 1
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
    • De Berardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008;7(1):11-20.
    • (2008) Cell Metab , vol.7 , Issue.1 , pp. 11-20
    • De Berardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 2
    • 84961287801 scopus 로고    scopus 로고
    • Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation
    • Sellers K, et al. Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. J Clin Invest. 2015;125(2):687-698.
    • (2015) J Clin Invest , vol.125 , Issue.2 , pp. 687-698
    • Sellers, K.1
  • 3
    • 68549085318 scopus 로고    scopus 로고
    • Altered regulation of metabolic pathways in human lung cancer discerned by (13) C stable isotope-resolved metabolomics (SIRM)
    • Fan TW, et al. Altered regulation of metabolic pathways in human lung cancer discerned by (13) C stable isotope-resolved metabolomics (SIRM). Mol Cancer. 2009;8:41.
    • (2009) Mol Cancer , vol.8 , pp. 41
    • Fan, T.W.1
  • 4
    • 79955398591 scopus 로고    scopus 로고
    • Otto Warburg's contributions to current concepts of cancer metabolism
    • Koppenol WH, Bounds PL, Dang CV. Otto Warburg's contributions to current concepts of cancer metabolism. Nat Rev Cancer. 2011;11(5):325-337.
    • (2011) Nat Rev Cancer , vol.11 , Issue.5 , pp. 325-337
    • Koppenol, W.H.1    Bounds, P.L.2    Dang, C.V.3
  • 6
    • 37449034854 scopus 로고    scopus 로고
    • Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    • De Berardinis RJ, et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A. 2007;104(49):19345-19350.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.49 , pp. 19345-19350
    • De Berardinis, R.J.1
  • 7
    • 84863011452 scopus 로고    scopus 로고
    • The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
    • Yuneva MO, et al. The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metab. 2012;15(2):157-170.
    • (2012) Cell Metab , vol.15 , Issue.2 , pp. 157-170
    • Yuneva, M.O.1
  • 8
    • 84866303235 scopus 로고    scopus 로고
    • Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors
    • Marin-Valencia I, et al. Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors. NMR Biomed. 2012;25(10):1177-1186.
    • (2012) NMR Biomed , vol.25 , Issue.10 , pp. 1177-1186
    • Marin-Valencia, I.1
  • 9
    • 84862016091 scopus 로고    scopus 로고
    • Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo
    • Marin-Valencia I, et al. Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo. Cell Metab. 2012;15(6):827-837.
    • (2012) Cell Metab , vol.15 , Issue.6 , pp. 827-837
    • Marin-Valencia, I.1
  • 10
    • 84868117861 scopus 로고    scopus 로고
    • Metabolism of [U-13 C]glucose in human brain tumors in vivo
    • Maher EA, et al. Metabolism of [U-13 C]glucose in human brain tumors in vivo. NMR Biomed. 2012;25(11):1234-1244.
    • (2012) NMR Biomed , vol.25 , Issue.11 , pp. 1234-1244
    • Maher, E.A.1
  • 11
    • 64749116346 scopus 로고    scopus 로고
    • C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
    • Gao P, et al. c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature. 2009;458(7239):762-765.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 762-765
    • Gao, P.1
  • 12
    • 57749088701 scopus 로고    scopus 로고
    • Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
    • Wise DR, et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc Natl Acad Sci U S A. 2008;105(48):18782-18787.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.48 , pp. 18782-18787
    • Wise, D.R.1
  • 13
    • 34347402459 scopus 로고    scopus 로고
    • Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
    • Yuneva M, Zamboni N, Oefner P, Sachidanandam R, Lazebnik Y. Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. J Cell Biol. 2007;178(1):93-105.
    • (2007) J Cell Biol , vol.178 , Issue.1 , pp. 93-105
    • Yuneva, M.1    Zamboni, N.2    Oefner, P.3    Sachidanandam, R.4    Lazebnik, Y.5
  • 14
    • 79957774646 scopus 로고    scopus 로고
    • Pyruvate carboxylase is required for glutamine-independent growth of tumor cells
    • Cheng T, et al. Pyruvate carboxylase is required for glutamine-independent growth of tumor cells. Proc Natl Acad Sci U S A. 2011;108(21):8674-8679.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.21 , pp. 8674-8679
    • Cheng, T.1
  • 15
    • 84896880417 scopus 로고    scopus 로고
    • Simultaneous steady-state and dynamic 13C NMR can differentiate alternative routes of pyruvate metabolism in living cancer cells
    • Yang C, et al. Simultaneous steady-state and dynamic 13C NMR can differentiate alternative routes of pyruvate metabolism in living cancer cells. J Biol Chem. 2014;289(9):6212-6224.
    • (2014) J Biol Chem , vol.289 , Issue.9 , pp. 6212-6224
    • Yang, C.1
  • 16
    • 77955653743 scopus 로고    scopus 로고
    • Pyruvate carboxylase deficiency: Mechanisms, mimics and anaplerosis
    • Marin-Valencia I, Roe CR, Pascual JM. Pyruvate carboxylase deficiency: mechanisms, mimics and anaplerosis. Mol Genet Metab. 2010;101(1):9-17.
    • (2010) Mol Genet Metab , vol.101 , Issue.1 , pp. 9-17
    • Marin-Valencia, I.1    Roe, C.R.2    Pascual, J.M.3
  • 17
    • 84919903877 scopus 로고    scopus 로고
    • Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
    • Mashimo T, et al. Acetate is a bioenergetic substrate for human glioblastoma and brain metastases. Cell. 2014;159(7):1603-1614.
    • (2014) Cell , vol.159 , Issue.7 , pp. 1603-1614
    • Mashimo, T.1
  • 18
    • 84893687735 scopus 로고    scopus 로고
    • Could magnetic resonance provide in vivo histology?
    • Dominietto M, Rudin M. Could magnetic resonance provide in vivo histology? Front Genet. 2014;4:298.
    • (2014) Front Genet , vol.4 , pp. 298
    • Dominietto, M.1    Rudin, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.