Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors

NMR in Biomedicine

Volumn 25, Issue 10, 2012, Pages 1177-1186

  Marin Valencia, Isaac ^a,b   Cho, Steve K ^b,c   Rakheja, Dinesh ^d   Hatanpaa, Kimmo J ^b,d   Kapur, Payal ^d   Mashimo, Tomoyuki ^b,c   Jindal, Ashish ^b   Vemireddy, Vamsidhara ^b,c,d   Good, Levi B ^b   Raisanen, Jack ^b,c   Sun, Xiankai ^b   Mickey, Bruce ^b,c   Choi, Changho ^c   Takahashi, Masaya ^b,c   Togao, Osamu ^b,c   Pascual, Juan M ^b   Deberardinis, Ralph J ^b,c   Maher, Elizabeth A ^b,c,d   Malloy, Craig R ^b,c   Bachoo, Robert M ^b,c,d  

^a Medical Service Veterans Affairs North Texas Healthcare System   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

13C NMR; Brain; Glioblastoma; Intermediary metabolism; Mouse model; Renal cell carcinoma

Indexed keywords

AMINOBUTYRIC ACIDS; BRAIN METASTASIS; CANCER DIAGNOSIS; GLIOBLASTOMAS; GLUCOSE METABOLISM; GLUCOSE OXIDATION; GLUTAMATE DECARBOXYLASE; HUMAN BRAIN TUMORS; IN-VIVO; INTERMEDIARY METABOLISM; ISOFORMS; KREBS CYCLE; MALIGNANT CELLS; METABOLIC DEMANDS; MOUSE MODELS; ORTHOTOPIC; PENTOSE PHOSPHATE PATHWAY; RENAL CELL; RENAL CELL CARCINOMA; RENAL TUMORS; TISSUE MICROARRAYS; TUMOR METABOLISMS;

AMINO ACIDS; BRAIN; BRAIN MODELS; CELLS; CYTOLOGY; DIAGNOSIS; GLUCOSE; INTERNET PROTOCOLS; LAKES; MAMMALS; METABOLISM; OXIDATION; PATHOLOGY; PHYSIOLOGY; REACTION INTERMEDIATES; TUMORS;

C (PROGRAMMING LANGUAGE);

4 AMINOBUTYRIC ACID; CARBON 13; GLUCOSE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 67; GLUTAMIC ACID; LACTIC ACID; PENTOSE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN METASTASIS; BRAIN TUMOR; CANCER GROWTH; CARBON NUCLEAR MAGNETIC RESONANCE; CITRIC ACID CYCLE; GLIOBLASTOMA; GLUCOSE METABOLISM; GLUCOSE OXIDATION; GLYCEMIC CONTROL; GLYCOLYSIS; HUMAN; HUMAN TISSUE; KIDNEY CARCINOMA; KIDNEY MASS; KIDNEY TUMOR; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TISSUE MICROARRAY; TUMOR VOLUME;

ANIMALS; BRAIN NEOPLASMS; CARCINOMA, RENAL CELL; CITRIC ACID CYCLE; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; GLIOBLASTOMA; GLUCOSE; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; GLYCOLYSIS; HUMANS; KIDNEY NEOPLASMS; LACTIC ACID; MAGNETIC RESONANCE IMAGING; MICE; PENTOSE PHOSPHATE PATHWAY; POSITRON-EMISSION TOMOGRAPHY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84866303235     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.2787     Document Type: Article

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