RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells

Apoptosis

Volumn 20, Issue 1, 2015, Pages 92-109

  Chen, Guozhu ^a   Cheng, Xiang ^a   Zhao, Ming ^a   Lin, Song ^a   Lu, Jiangyang ^b   Kang, Jiarui ^b   Yu, Xiaodan ^a  

^a Beijing Institute of Basic Medical Sciences   (China)

^b Department of Pathology First Affiliate Hospital of PLA   (China)

Author keywords

Bid cleavage; L929 fibroblastoma cells; L929 fibrosarcoma cells; Necrosis; RIP1; RIP3; TNF

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CELL PROTEIN; NECROSTATIN 1; PROTEIN BID; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RIP1 PROTEIN; RIP3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; BID PROTEIN, MOUSE; CASPASE INHIBITOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PEPTIDE CHLOROMETHYL KETONE; RALBP1 PROTEIN, MOUSE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL DEATH; CELL FUNCTION; CELL ISOLATION; CELL KILLING; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; FIBROSARCOMA CELL; HUMAN; HUMAN CELL; L929 CELL LINE; MEDIATOR; MITOCHONDRION; NECROPTOSIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; DERMATOFIBROSARCOMA PROTUBERANS; DRUG EFFECTS; METABOLISM; MOUSE; PATHOLOGY; SKIN TUMOR; TUMOR CELL LINE;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CASPASE 8; CASPASE INHIBITORS; CELL DEATH; CELL LINE, TUMOR; DERMATOFIBROSARCOMA; GTPASE-ACTIVATING PROTEINS; MICE; MITOCHONDRIA; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SKIN NEOPLASMS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84922076378     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-1058-0     Document Type: Article

References (66)

1. Berghe TV et al (2009) Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features. Cell Death Differ 17(6):922-930
2. Kroemer G et al (2008) Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 16(1):3-11
3. Christofferson DE, Yuan J (2010) Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 22(2):263-268
4. Han J, Zhong C-Q, Zhang D-W (2011) Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol 12(12):1143-1149
5. Dickens LS et al (2012) The 'complexities' of life and death: death receptor signalling platforms. Exp Cell Res 318(11):1269-1277
6. Festjens N et al (2007) RIP1, a kinase on the crossroads of a cell's decision to live or die. Cell Death Differ 14(3):400-410
7. O'Donnell MA et al (2007) Ubiquitination of RIP1 regulates an NF-κB-independent cell-death switch in TNF signaling. Curr Biol 17(5):418-424
8. Wang L, Du F, Wang X (2008) TNF-α induces two distinct Caspase-8 activation pathways. Cell 133(4):693-703
9. Vanlangenakker N et al (2011) TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members. Cell Death Dis 2(11):e230
10. Micheau O, Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114(2):181-190
11. Luo X et al (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94(4):481-490
12. Li H et al (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94(4):491-501
13. Cho Y et al (2009) Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation. Cell 137(6):1112-1123
14. He S et al (2009) Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α. Cell 137(6):1100-1111
15. Zhang DW et al (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325(5938):332-336
16. O'Donnell MA et al (2011) Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 13(12):1437-1442
17. Vanlangenakker N, Vanden Berghe T, Vandenabeele P (2011) Many stimuli pull the necrotic trigger, an overview. Cell Death Differ 19(1):75-86
18. Feoktistova M et al (2011) cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 43(3):449-463
19. Tenev T et al (2011) The ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 43(3):432-448
20. Humphreys DT, Wilson MR (1999) Modes of L929 cell death induced by TNF-alpha and other cytotoxic agents. Cytokine 11(10):773-782
21. Fady C et al (1995) Atypical apoptotic cell death induced in L929 targets by exposure to tumor necrosis factor. J Interferon Cytokine Res 15(1):71-80
22. Mirkina II et al (1996) Cytolytic processes induced by TNF in L929 and K562 differ in DNA fragmentation mechanisms. Immunol Lett 52(2-3):105-108
23. Wang J et al (2010) Selective unresponsiveness to the inhibition of p38 MAPK activation by cAMP helps L929 fibroblastoma cells escape TNF-alpha-induced cell death. Mol Cancer 9:6
24. Vercammen D et al (1998) Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways. J Exp Med 188(5):919-930
25. Vercammen D et al (1997) Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells. Cytokine 9(11):801-808
26. Grooten J et al (1993) Cell membrane permeabilization and cellular collapse, followed by loss of dehydrogenase activity: early events in tumour necrosis factor-induced cytotoxicity. Cytokine 5(6):546-555
27. Cho Y et al (2011) RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation. PLoS One 6(8):e23209
28. Ye YC et al (2011) TNFalpha-induced necroptosis and autophagy via supression of the p38-NF-kappaB survival pathway in L929 cells. J Pharmacol Sci 117(3):160-169
29. Wu YT et al (2008) Autophagy plays a protective role during zVAD-induced necrotic cell death. Autophagy 4(4):457-466
30. Vercammen D et al (1998) Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 187(9):1477-1485
31. Wu YT et al (2010) zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ 18(1):26-37
32. Newton K et al (2014) Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Science 343(6177):1357-1360
33. Slee EA, Keogh SA, Martin SJ (2000) Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release. Cell Death Differ 7(6):556-565
34. Deng Y et al (2003) A JNK-dependent pathway is required for TNFalpha-induced apoptosis. Cell 115(1):61-70
35. Sakon S et al (2003) NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J 22(15):3898-3909
36. Kamata H et al (2005) Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120(5):649-661
37. Cabon L et al (2011) BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation. Cell Death Differ 19(2):245-256
38. Droga-Mazovec G et al (2008) Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. J Biol Chem 283(27):19140-19150
39. Miao Q et al (2008) Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway. J Biol Chem 283(13):8218-8228
40. Smith DJ et al (2008) The mitochondrial gateway to cell death. IUBMB Life 60(6):383-389
41. Jourdain A, Martinou J-C (2009) Mitochondrial outer-membrane permeabilization and remodelling in apoptosis. Int J Biochem Cell Biol 41(10):1884-1889
42. Chen SY et al (2011) zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation. Autophagy 7(2):217-228
43. Tischner D et al (2012) Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members. Apoptosis 17(11):1197-1209
44. Samraj AK et al (2006) Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis. J Biol Chem 281(40):29652-29659
45. Feoktistova M et al (2012) Pick your poison: the Ripoptosome, a cell death platform regulating apoptosis and necroptosis. Cell Cycle 11(3):460-467
46. Ye YC et al (2012) RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy. Int Immunopharmacol 14(4):674-682
47. Song G et al (2010) Bid stands at the crossroad of stress-response pathways. Curr Cancer Drug Targets 10(6):584-592
48. Milhas D et al (2005) Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis. J Biol Chem 280(20):19836-19842
49. Upton JP et al (2008) Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress. Mol Cell Biol 28(12):3943-3951
50. Wagner KW, Engels IH, Deveraux QL (2004) Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway. J Biol Chem 279(33):35047-35052
51. Guicciardi ME et al (2005) Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis. Gastroenterology 129(1):269-284
52. Mandic A et al (2002) Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis. Mol Cell Biol 22(9):3003-3013
53. Sutton VR et al (2000) Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation. J Exp Med 192(10):1403-1414
54. Stoka V et al (2001) Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J Biol Chem 276(5):3149-3157
55. Yin XM (2006) Bid, a BH3-only multi-functional molecule, is at the cross road of life and death. Gene 369:7-19
56. Festjens N et al (2005) Butylated hydroxyanisole is more than a reactive oxygen species scavenger. Cell Death Differ 13(1):166-169
57. Wang X (2001) The expanding role of mitochondria in apoptosis. Genes Dev 15(22):2922-2933
58. Yoshii SR et al (2011) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem 286(22):19630-19640
59. Geisler S et al (2010) PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 12(2):119-131
60. Whelan RS et al (2012) Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci USA 109(17):6566-6571
61. Hoppins S et al (2011) The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes. Mol Cell 41(2):150-160
62. Wu S et al (2011) Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy. J Cell Physiol 226(2):530-541
63. Sheridan C et al (2008) Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release. Mol Cell 31(4):570-585
64. Karbowski M et al (2002) Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J Cell Biol 159(6):931-938
65. Arnoult D et al (2005) Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death. Curr Biol 15(23):2112-2118
66. Lyamzaev KG et al (2008) Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell. Biochim Biophys Acta 1777(7-8):817-825