-
1
-
-
84922053748
-
-
Overweight and obesity: data and statistics. Available from URL: Accessed 9 September 2014.
-
Center for Disease Control and Prevention. Overweight and obesity: data and statistics. 2014. Available from URL: http://www.cdc.gov/obesity/data/index.html. Accessed 9 September 2014.
-
(2014)
-
-
-
2
-
-
74549140993
-
Prevalence and trends in obesity among US adults, 1999-2008
-
Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010; 303: 235-241.
-
(2010)
JAMA
, vol.303
, pp. 235-241
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Curtin, L.R.4
-
3
-
-
70349207410
-
Annual medical spending attributable to obesity: payer-and service-specific estimates
-
Finkelstein EA, Trogdon JG, Cohen JW, Dietz W. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood) 2009; 28: w822-831.
-
(2009)
Health Aff (Millwood)
, vol.28
, pp. w822-w831
-
-
Finkelstein, E.A.1
Trogdon, J.G.2
Cohen, J.W.3
Dietz, W.4
-
4
-
-
84860243253
-
Liraglutide: short-lived effect on gastric emptying - long lasting effects on body weight
-
Jelsing J, Vrang N, Hansen G, Raun K, Tang-Christensen M, Knudsen LB. Liraglutide: short-lived effect on gastric emptying - long lasting effects on body weight. Diabetes Obes Metab 2012; 14: 531-538.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 531-538
-
-
Jelsing, J.1
Vrang, N.2
Hansen, G.3
Raun, K.4
Tang-Christensen, M.5
Knudsen, L.B.6
-
5
-
-
84865070709
-
Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes
-
Horowitz M, Flint A, Jones KL et al. Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes. Diabetes Res Clin Pract 2012; 97: 258-266.
-
(2012)
Diabetes Res Clin Pract
, vol.97
, pp. 258-266
-
-
Horowitz, M.1
Flint, A.2
Jones, K.L.3
-
6
-
-
79959675075
-
Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats
-
Hayes MR, Kanoski SE, Alhadeff AL, Grill HJ. Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats. Obesity (Silver Spring) 2011; 19: 1342-1349.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1342-1349
-
-
Hayes, M.R.1
Kanoski, S.E.2
Alhadeff, A.L.3
Grill, H.J.4
-
7
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
-
Astrup A, Rossner S, Van Gaal L et al. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009; 374: 1606-1616.
-
(2009)
Lancet
, vol.374
, pp. 1606-1616
-
-
Astrup, A.1
Rossner, S.2
Van Gaal, L.3
-
8
-
-
34547951456
-
Liraglutide, a once-daily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs
-
Raun K, von Voss P, Knudsen LB. Liraglutide, a once-daily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs. Obesity (Silver Spring) 2007; 15: 1710-1716.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 1710-1716
-
-
Raun, K.1
von Voss, P.2
Knudsen, L.B.3
-
11
-
-
33845518516
-
Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation
-
Williams DL, Baskin DG, Schwartz MW. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes 2006; 55: 3387-3393.
-
(2006)
Diabetes
, vol.55
, pp. 3387-3393
-
-
Williams, D.L.1
Baskin, D.G.2
Schwartz, M.W.3
-
12
-
-
34347406528
-
Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat
-
Bojanowska E, Nowak A. Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat. J Physiol Pharmacol 2007; 58: 349-360.
-
(2007)
J Physiol Pharmacol
, vol.58
, pp. 349-360
-
-
Bojanowska, E.1
Nowak, A.2
-
13
-
-
0031590319
-
Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents
-
Goldstone AP, Mercer JG, Gunn I et al. Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents. FEBS Lett 1997; 415: 134-138.
-
(1997)
FEBS Lett
, vol.415
, pp. 134-138
-
-
Goldstone, A.P.1
Mercer, J.G.2
Gunn, I.3
-
14
-
-
53649107145
-
Effects of peripheral or central GLP-1 receptor blockade on leptin-induced suppression of appetite
-
Nowak A, Bojanowska E. Effects of peripheral or central GLP-1 receptor blockade on leptin-induced suppression of appetite. J Physiol Pharmacol 2008; 59: 501-510.
-
(2008)
J Physiol Pharmacol
, vol.59
, pp. 501-510
-
-
Nowak, A.1
Bojanowska, E.2
-
15
-
-
84871005992
-
Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner
-
Zhao S, Kanoski SE, Yan J, Grill HJ, Hayes MR. Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner. Int J Obes 2012; 36: 1522-1528.
-
(2012)
Int J Obes
, vol.36
, pp. 1522-1528
-
-
Zhao, S.1
Kanoski, S.E.2
Yan, J.3
Grill, H.J.4
Hayes, M.R.5
-
16
-
-
0034673568
-
Effect of leptin on hypothalamic GLP-1 peptide and brain-stem pre-proglucagon mRNA
-
Goldstone AP, Morgan I, Mercer JG et al. Effect of leptin on hypothalamic GLP-1 peptide and brain-stem pre-proglucagon mRNA. Biochem Biophys Res Commun 2000; 269: 331-335.
-
(2000)
Biochem Biophys Res Commun
, vol.269
, pp. 331-335
-
-
Goldstone, A.P.1
Morgan, I.2
Mercer, J.G.3
-
17
-
-
36849041597
-
Leptin but not neuropeptide Y up-regulated glucagon-like peptide 1 receptor expression in GT1-7 cells and rat hypothalamic slices
-
Sanz C, Vazquez P, Navas MA, Alvarez E, Blazquez E. Leptin but not neuropeptide Y up-regulated glucagon-like peptide 1 receptor expression in GT1-7 cells and rat hypothalamic slices. Metabolism 2008; 57: 40-48.
-
(2008)
Metabolism
, vol.57
, pp. 40-48
-
-
Sanz, C.1
Vazquez, P.2
Navas, M.A.3
Alvarez, E.4
Blazquez, E.5
-
18
-
-
34548390977
-
The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
-
Scott KA, Moran TH. The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size. Am J Physiol Regul Integr Comp Physiol 2007; 293: R983-987.
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
, pp. R983-R987
-
-
Scott, K.A.1
Moran, T.H.2
-
19
-
-
63849248275
-
Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
-
Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009; 150: 1680-1687.
-
(2009)
Endocrinology
, vol.150
, pp. 1680-1687
-
-
Williams, D.L.1
Baskin, D.G.2
Schwartz, M.W.3
-
20
-
-
84888860281
-
The food intake-suppressive effects of glucagon-like peptide-1 receptor signaling in the ventral tegmental area are mediated by AMPA/kainate receptors
-
Mietlicki-Baase EG, Ortinski PI, Rupprecht LE et al. The food intake-suppressive effects of glucagon-like peptide-1 receptor signaling in the ventral tegmental area are mediated by AMPA/kainate receptors. Am J Physiol Endocrinol Metab 2013; 305: E1367-1374.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
, pp. E1367-E1374
-
-
Mietlicki-Baase, E.G.1
Ortinski, P.I.2
Rupprecht, L.E.3
-
21
-
-
84922053747
-
Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission
-
Hsu TM, Hahn JD, Konanur VR, Lam A, Kanoski SE. Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission. Neuropsychopharmacology 2015; 40: 327-337.
-
(2015)
Neuropsychopharmacology
, vol.40
, pp. 327-337
-
-
Hsu, T.M.1
Hahn, J.D.2
Konanur, V.R.3
Lam, A.4
Kanoski, S.E.5
-
22
-
-
0031846614
-
Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats
-
Eckel LA, Langhans W, Kahler A, Campfield LA, Smith FJ, Geary N. Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats. Am J Physiol 1998; 275: R186-193.
-
(1998)
Am J Physiol
, vol.275
, pp. R186-R193
-
-
Eckel, L.A.1
Langhans, W.2
Kahler, A.3
Campfield, L.A.4
Smith, F.J.5
Geary, N.6
-
23
-
-
0031846614
-
Chronic administration of OB protein decreases food intake by selectively reducing meal size in male rats
-
Kahler A, Geary N, Eckel LA, Campfield LA, Smith FJ, Langhans W. Chronic administration of OB protein decreases food intake by selectively reducing meal size in male rats. Am J Physiol 1998; 275: R180-185.
-
(1998)
Am J Physiol
, vol.275
, pp. R180-R185
-
-
Kahler, A.1
Geary, N.2
Eckel, L.A.3
Campfield, L.A.4
Smith, F.J.5
Langhans, W.6
-
24
-
-
0024149607
-
Circadian feeding and drinking patterns of genetically obese mice fed solid chow diet
-
Ho A, Chin A. Circadian feeding and drinking patterns of genetically obese mice fed solid chow diet. Physiol Behav 1988; 43: 651-656.
-
(1988)
Physiol Behav
, vol.43
, pp. 651-656
-
-
Ho, A.1
Chin, A.2
-
25
-
-
84865147501
-
Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals
-
Kanoski SE, Zhao S, Guarnieri DJ et al. Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals. Am J Physiol Endocrinol Metab 2012; 303: E496-503.
-
(2012)
Am J Physiol Endocrinol Metab
, vol.303
, pp. E496-E503
-
-
Kanoski, S.E.1
Zhao, S.2
Guarnieri, D.J.3
-
26
-
-
12344263771
-
Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat
-
Zorrilla EP, Inoue K, Valdez GR, Tabarin A, Koob GF. Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat. Psychopharmacology (Berl) 2005; 177: 324-335.
-
(2005)
Psychopharmacology (Berl)
, vol.177
, pp. 324-335
-
-
Zorrilla, E.P.1
Inoue, K.2
Valdez, G.R.3
Tabarin, A.4
Koob, G.F.5
-
27
-
-
2342444310
-
Leptin receptor signaling and the regulation of mammalian physiology
-
Myers MG Jr. Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res 2004; 59: 287-304.
-
(2004)
Recent Prog Horm Res
, vol.59
, pp. 287-304
-
-
Myers, M.G.1
-
28
-
-
84885031186
-
Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6
-
Shirazi R, Palsdottir V, Collander J et al. Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6. Proc Natl Acad Sci U S A 2013; 110: 16199-16204.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 16199-16204
-
-
Shirazi, R.1
Palsdottir, V.2
Collander, J.3
-
29
-
-
0019794835
-
Glucoreceptors controlling feeding and blood glucose: location in the hindbrain
-
Ritter RC, Slusser PG, Stone S. Glucoreceptors controlling feeding and blood glucose: location in the hindbrain. Science 1981; 213: 451-452.
-
(1981)
Science
, vol.213
, pp. 451-452
-
-
Ritter, R.C.1
Slusser, P.G.2
Stone, S.3
-
30
-
-
84857045922
-
The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
-
Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR. The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide. Neuropharmacology 2012; 62: 1916-1927.
-
(2012)
Neuropharmacology
, vol.62
, pp. 1916-1927
-
-
Kanoski, S.E.1
Rupprecht, L.E.2
Fortin, S.M.3
De Jonghe, B.C.4
Hayes, M.R.5
-
31
-
-
0029763177
-
The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats. Reduced sensitivity compared with lean animals
-
Cusin I, Rohner-Jeanrenaud F, Stricker-Krongrad A, Jeanrenaud B. The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats. Reduced sensitivity compared with lean animals. Diabetes 1996; 45: 1446-1450.
-
(1996)
Diabetes
, vol.45
, pp. 1446-1450
-
-
Cusin, I.1
Rohner-Jeanrenaud, F.2
Stricker-Krongrad, A.3
Jeanrenaud, B.4
-
32
-
-
84876295102
-
Ghrelin signaling in the ventral hippocampus stimulates learned and motivational aspects of feeding via PI3K-Akt signaling
-
Kanoski SE, Fortin SM, Ricks KM, Grill HJ. Ghrelin signaling in the ventral hippocampus stimulates learned and motivational aspects of feeding via PI3K-Akt signaling. Biol Psychiatry 2013; 73: 915-923.
-
(2013)
Biol Psychiatry
, vol.73
, pp. 915-923
-
-
Kanoski, S.E.1
Fortin, S.M.2
Ricks, K.M.3
Grill, H.J.4
-
33
-
-
79952119299
-
Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation
-
Hayes MR, Leichner TM, Zhao S et al. Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation. Cell Metab 2011; 13: 320-330.
-
(2011)
Cell Metab
, vol.13
, pp. 320-330
-
-
Hayes, M.R.1
Leichner, T.M.2
Zhao, S.3
-
34
-
-
34547235565
-
Leptin inhibits gastric emptying in rats: role of CCK receptors and vagal afferent fibers
-
Cakir B, Kasimay O, Devseren E, Yegen BC. Leptin inhibits gastric emptying in rats: role of CCK receptors and vagal afferent fibers. Physiol Res 2007; 56: 315-322.
-
(2007)
Physiol Res
, vol.56
, pp. 315-322
-
-
Cakir, B.1
Kasimay, O.2
Devseren, E.3
Yegen, B.C.4
-
36
-
-
0022460685
-
Meal pattern analysis: artifacts, assumptions and implications
-
Castonguay TW, Kaiser LL, Stern JS. Meal pattern analysis: artifacts, assumptions and implications. Brain Res Bull 1986; 17: 439-443.
-
(1986)
Brain Res Bull
, vol.17
, pp. 439-443
-
-
Castonguay, T.W.1
Kaiser, L.L.2
Stern, J.S.3
-
37
-
-
0032144918
-
Mathematical determination of feeding patterns and its consequence on correlational studies
-
Demaria-Pesce VH, Nicolaidis S. Mathematical determination of feeding patterns and its consequence on correlational studies. Physiol Behav 1998; 65: 157-170.
-
(1998)
Physiol Behav
, vol.65
, pp. 157-170
-
-
Demaria-Pesce, V.H.1
Nicolaidis, S.2
-
38
-
-
0014731197
-
Free feeding in normal and "recovered lateral" rats monitored by a pellet-detecting eatometer
-
Kissileff HR. Free feeding in normal and "recovered lateral" rats monitored by a pellet-detecting eatometer. Physiol Behav 1970; 5: 163-173.
-
(1970)
Physiol Behav
, vol.5
, pp. 163-173
-
-
Kissileff, H.R.1
-
39
-
-
0033955690
-
Meal patterning in rodents: psychopharmacological and neuroanatomical studies
-
Clifton PG. Meal patterning in rodents: psychopharmacological and neuroanatomical studies. Neurosci Biobehav Rev 2000; 24: 213-222.
-
(2000)
Neurosci Biobehav Rev
, vol.24
, pp. 213-222
-
-
Clifton, P.G.1
-
40
-
-
79960741385
-
Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4
-
Kanoski SE, Fortin SM, Arnold M, Grill HJ, Hayes MR. Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4. Endocrinology 2011; 152: 3103-3112.
-
(2011)
Endocrinology
, vol.152
, pp. 3103-3112
-
-
Kanoski, S.E.1
Fortin, S.M.2
Arnold, M.3
Grill, H.J.4
Hayes, M.R.5
-
41
-
-
77957608672
-
Chronic administration of the glucagon-like peptide-1 analog, liraglutide, delays the onset of diabetes and lowers triglycerides in UCD-T2DM rats
-
Cummings BP, Stanhope KL, Graham JL et al. Chronic administration of the glucagon-like peptide-1 analog, liraglutide, delays the onset of diabetes and lowers triglycerides in UCD-T2DM rats. Diabetes 2010; 59: 2653-2661.
-
(2010)
Diabetes
, vol.59
, pp. 2653-2661
-
-
Cummings, B.P.1
Stanhope, K.L.2
Graham, J.L.3
-
42
-
-
33847072735
-
Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not
-
Raun K, von Voss P, Gotfredsen CF, Golozoubova V, Rolin B, Knudsen LB. Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not. Diabetes 2007; 56: 8-15.
-
(2007)
Diabetes
, vol.56
, pp. 8-15
-
-
Raun, K.1
von Voss, P.2
Gotfredsen, C.F.3
Golozoubova, V.4
Rolin, B.5
Knudsen, L.B.6
-
43
-
-
80054035293
-
Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake
-
Dossat AM, Lilly N, Kay K, Williams DL. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. J Neurosci 2011; 31: 14453-14457.
-
(2011)
J Neurosci
, vol.31
, pp. 14453-14457
-
-
Dossat, A.M.1
Lilly, N.2
Kay, K.3
Williams, D.L.4
-
44
-
-
67649636449
-
Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
-
Ruttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 2009; 150: 1174-1181.
-
(2009)
Endocrinology
, vol.150
, pp. 1174-1181
-
-
Ruttimann, E.B.1
Arnold, M.2
Hillebrand, J.J.3
Geary, N.4
Langhans, W.5
-
45
-
-
84902208322
-
Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect
-
Sisley S, Gutierrez-Aguilar R, Scott M, D'Alessio DA, Sandoval DA, Seeley RJ. Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. J Clin Invest 2014; 124: 2456-2463.
-
(2014)
J Clin Invest
, vol.124
, pp. 2456-2463
-
-
Sisley, S.1
Gutierrez-Aguilar, R.2
Scott, M.3
D'Alessio, D.A.4
Sandoval, D.A.5
Seeley, R.J.6
-
46
-
-
0036896243
-
The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness
-
Kinzig KP, D'Alessio DA, Seeley RJ. The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 2002; 22: 10470-10476.
-
(2002)
J Neurosci
, vol.22
, pp. 10470-10476
-
-
Kinzig, K.P.1
D'Alessio, D.A.2
Seeley, R.J.3
-
47
-
-
0032527071
-
Distributions of leptin receptor mRNA isoforms in the rat brain
-
Elmquist JK, Bjorbaek C, Ahima RS, Flier JS, Saper CB. Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol 1998; 395: 535-547.
-
(1998)
J Comp Neurol
, vol.395
, pp. 535-547
-
-
Elmquist, J.K.1
Bjorbaek, C.2
Ahima, R.S.3
Flier, J.S.4
Saper, C.B.5
-
48
-
-
0033545166
-
Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
-
Merchenthaler I, Lane M, Shughrue P. Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. J Comp Neurol 1999; 403: 261-280.
-
(1999)
J Comp Neurol
, vol.403
, pp. 261-280
-
-
Merchenthaler, I.1
Lane, M.2
Shughrue, P.3
-
50
-
-
84899803440
-
Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet
-
Wu Y, Yu Y, Szabo A, Han M, Huang XF. Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet. PLoS One 2014; 9: e92618.
-
(2014)
PLoS One
, vol.9
, pp. e92618
-
-
Wu, Y.1
Yu, Y.2
Szabo, A.3
Han, M.4
Huang, X.F.5
-
51
-
-
0035930501
-
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B
-
Myers MP, Andersen JN, Cheng A et al. TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B. J Biol Chem 2001; 276: 47771-47774.
-
(2001)
J Biol Chem
, vol.276
, pp. 47771-47774
-
-
Myers, M.P.1
Andersen, J.N.2
Cheng, A.3
-
53
-
-
33746810001
-
Neuronal PTP1B regulates body weight, adiposity and leptin action
-
Bence KK, Delibegovic M, Xue B et al. Neuronal PTP1B regulates body weight, adiposity and leptin action. Nat Med 2006; 12: 917-924.
-
(2006)
Nat Med
, vol.12
, pp. 917-924
-
-
Bence, K.K.1
Delibegovic, M.2
Xue, B.3
-
54
-
-
33845882537
-
Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age
-
Morrison CD, White CL, Wang Z et al. Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age. Endocrinology 2007; 148: 433-440.
-
(2007)
Endocrinology
, vol.148
, pp. 433-440
-
-
Morrison, C.D.1
White, C.L.2
Wang, Z.3
-
55
-
-
84922021588
-
Frank Beach Award Winner: steroids as neuromodulators of brain circuits and behavior
-
Remage-Healey L. Frank Beach Award Winner: steroids as neuromodulators of brain circuits and behavior. Horm Behav 2014; 66: 552-560.
-
(2014)
Horm Behav
, vol.66
, pp. 552-560
-
-
Remage-Healey, L.1
-
56
-
-
0029908224
-
Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain
-
Van Dijk G, Thiele TE, Donahey JC et al. Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain. Am J Physiol 1996; 271: R1096-1100.
-
(1996)
Am J Physiol
, vol.271
, pp. R1096-R1100
-
-
Van Dijk, G.1
Thiele, T.E.2
Donahey, J.C.3
-
57
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley MA, Smart JL, Rubinstein M et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 2001; 411: 480-484.
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
-
58
-
-
84907495472
-
The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss
-
Secher A, Jelsing J, Baquero AF et al. The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss. J Clin Invest 2014; 124: 4473-4488.
-
(2014)
J Clin Invest
, vol.124
, pp. 4473-4488
-
-
Secher, A.1
Jelsing, J.2
Baquero, A.F.3
-
59
-
-
84856102513
-
GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake
-
Alhadeff AL, Rupprecht LE, Hayes MR. GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake. Endocrinology 2012; 153: 647-658.
-
(2012)
Endocrinology
, vol.153
, pp. 647-658
-
-
Alhadeff, A.L.1
Rupprecht, L.E.2
Hayes, M.R.3
-
60
-
-
33748540764
-
Leptin receptor signaling in midbrain dopamine neurons regulates feeding
-
Hommel JD, Trinko R, Sears RM et al. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron 2006; 51: 801-810.
-
(2006)
Neuron
, vol.51
, pp. 801-810
-
-
Hommel, J.D.1
Trinko, R.2
Sears, R.M.3
-
61
-
-
79960326683
-
Hippocampal leptin signaling reduces food intake and modulates food-related memory processing
-
Kanoski SE, Hayes MR, Greenwald HS et al. Hippocampal leptin signaling reduces food intake and modulates food-related memory processing. Neuropsychopharmacology 2011; 36: 1859-1870.
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 1859-1870
-
-
Kanoski, S.E.1
Hayes, M.R.2
Greenwald, H.S.3
-
62
-
-
84900030527
-
Liraglutide suppresses obesity and hyperglycemia associated with increases in hepatic fibroblast growth factor 21 production in KKAy mice
-
Nonogaki K, Hazama M, Satoh N. Liraglutide suppresses obesity and hyperglycemia associated with increases in hepatic fibroblast growth factor 21 production in KKAy mice. Biomed Res Int 2014; 2014: 751930.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 751930
-
-
Nonogaki, K.1
Hazama, M.2
Satoh, N.3
-
63
-
-
84869051421
-
Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance
-
Yang M, Zhang L, Wang C et al. Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance. PLoS One 2012; 7: e48392.
-
(2012)
PLoS One
, vol.7
, pp. e48392
-
-
Yang, M.1
Zhang, L.2
Wang, C.3
-
64
-
-
85027936258
-
Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
-
Muller TD, Sullivan LM, Habegger K et al. Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21. J Pept Sci 2012; 18: 383-393.
-
(2012)
J Pept Sci
, vol.18
, pp. 383-393
-
-
Muller, T.D.1
Sullivan, L.M.2
Habegger, K.3
-
65
-
-
77954277205
-
Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats
-
Sarruf DA, Thaler JP, Morton GJ et al. Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats. Diabetes 2010; 59: 1817-1824.
-
(2010)
Diabetes
, vol.59
, pp. 1817-1824
-
-
Sarruf, D.A.1
Thaler, J.P.2
Morton, G.J.3
|