-
1
-
-
34748823479
-
Social isolation affects the development of obesity and type 2 diabetes in mice
-
2-s2.0-34748823479 10.1210/en.2007-0296
-
Nonogaki K., Nozue K., Oka Y., Social isolation affects the development of obesity and type 2 diabetes in mice. Endocrinology 2007 148 10 4658 4666 2-s2.0-34748823479 10.1210/en.2007-0296
-
(2007)
Endocrinology
, vol.148
, Issue.10
, pp. 4658-4666
-
-
Nonogaki, K.1
Nozue, K.2
Oka, Y.3
-
2
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
2-s2.0-35748957503 10.1152/physrev.00034.2006
-
Holst J. J., The physiology of glucagon-like peptide 1. Physiological Reviews 2007 87 4 1409 1439 2-s2.0-35748957503 10.1152/physrev.00034.2006
-
(2007)
Physiological Reviews
, vol.87
, Issue.4
, pp. 1409-1439
-
-
Holst, J.J.1
-
4
-
-
67651173077
-
Incretin-based therapies for type 2 diabetes mellitus
-
2-s2.0-67651173077 10.1038/nrendo.2009.48
-
Lovshin J. A., Drucker D. J., Incretin-based therapies for type 2 diabetes mellitus. Nature Reviews Endocrinology 2009 5 5 262 269 2-s2.0-67651173077 10.1038/nrendo.2009.48
-
(2009)
Nature Reviews Endocrinology
, vol.5
, Issue.5
, pp. 262-269
-
-
Lovshin, J.A.1
Drucker, D.J.2
-
5
-
-
34248999413
-
Discovery of alogliptin: A potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV
-
2-s2.0-34248999413 10.1021/jm070104l
-
Feng J., Zhang Z., Wallace M. B., Stafford J. A., Kaldor S. W., Kassel D. B., Navre M., Shi L., Skene R. J., Asakawa T., Takeuchi K., Xu R., Webb D. R., Gwaltney S. L. II, Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV. Journal of Medicinal Chemistry 2007 50 10 2297 2300 2-s2.0-34248999413 10.1021/jm070104l
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.10
, pp. 2297-2300
-
-
Feng, J.1
Zhang, Z.2
Wallace, M.B.3
Stafford, J.A.4
Kaldor, S.W.5
Kassel, D.B.6
Navre, M.7
Shi, L.8
Skene, R.J.9
Asakawa, T.10
Takeuchi, K.11
Xu, R.12
Webb, D.R.13
Gwaltney, S.L.I.I.14
-
6
-
-
46549083771
-
Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys
-
2-s2.0-46549083771 10.1016/j.ejphar.2008.04.047
-
Lee B., Shi L., Kassel D. B., Asakawa T., Takeuchi K., Christopher R. J., Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys. European Journal of Pharmacology 2008 589 1-3 306 314 2-s2.0-46549083771 10.1016/j.ejphar.2008.04.047
-
(2008)
European Journal of Pharmacology
, vol.589
, Issue.1-3
, pp. 306-314
-
-
Lee, B.1
Shi, L.2
Kassel, D.B.3
Asakawa, T.4
Takeuchi, K.5
Christopher, R.J.6
-
7
-
-
58149144587
-
The dipeptidyl peptidase-4 inhibitor alogliptin in combination with pioglitazone improves glycemic control, lipid profiles, and increases pancreatic insulin content in ob/ob mice
-
2-s2.0-58149144587 10.1016/j.ejphar.2008.11.017
-
Moritoh Y., Takeuchi K., Asakawa T., Kataoka O., Odaka H., The dipeptidyl peptidase-4 inhibitor alogliptin in combination with pioglitazone improves glycemic control, lipid profiles, and increases pancreatic insulin content in ob/ob mice. European Journal of Pharmacology 2009 602 2-3 448 454 2-s2.0-58149144587 10.1016/j.ejphar.2008.11.017
-
(2009)
European Journal of Pharmacology
, vol.602
, Issue.2-3
, pp. 448-454
-
-
Moritoh, Y.1
Takeuchi, K.2
Asakawa, T.3
Kataoka, O.4
Odaka, H.5
-
8
-
-
70349918275
-
Combining a dipeptidyl peptidase-4 inhibitor, alogliptin, with pioglitazone improves glycaemic control, lipid profiles and β -cell function in db/db mice
-
2-s2.0-70349918275 10.1111/j.1476-5381.2009.00145.x
-
Moritoh Y., Takeuchi K., Asakawa T., Kataoka O., Odaka H., Combining a dipeptidyl peptidase-4 inhibitor, alogliptin, with pioglitazone improves glycaemic control, lipid profiles and β -cell function in db/db mice. British Journal of Pharmacology 2009 157 3 415 426 2-s2.0-70349918275 10.1111/j.1476-5381.2009.00145.x
-
(2009)
British Journal of Pharmacology
, vol.157
, Issue.3
, pp. 415-426
-
-
Moritoh, Y.1
Takeuchi, K.2
Asakawa, T.3
Kataoka, O.4
Odaka, H.5
-
9
-
-
79960839795
-
The contribution of serotonin 5-HT2C and melanocortin-4 receptors to the satiety signaling of glucagon-like peptide 1 and liragultide, a glucagon-like peptide 1 receptor agonist, in mice
-
2-s2.0-79960839795 10.1016/j.bbrc.2011.06.175
-
Nonogaki K., Suzuki M., Sanuki M., Wakameda M., Tamari T., The contribution of serotonin 5-HT2C and melanocortin-4 receptors to the satiety signaling of glucagon-like peptide 1 and liragultide, a glucagon-like peptide 1 receptor agonist, in mice. Biochemical and Biophysical Research Communications 2011 411 2 445 448 2-s2.0-79960839795 10.1016/j.bbrc.2011.06.175
-
(2011)
Biochemical and Biophysical Research Communications
, vol.411
, Issue.2
, pp. 445-448
-
-
Nonogaki, K.1
Suzuki, M.2
Sanuki, M.3
Wakameda, M.4
Tamari, T.5
-
10
-
-
80052614033
-
DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice β cells
-
2-s2.0-80052614033 10.1016/j.bbrc.2011.07.119
-
Nagamatsu S., Ohara-Imaizumi M., Nakamichi Y., Aoyagi K., Nishiwaki C., DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice β cells. Biochemical and Biophysical Research Communications 2011 412 4 556 560 2-s2.0-80052614033 10.1016/j.bbrc.2011.07.119
-
(2011)
Biochemical and Biophysical Research Communications
, vol.412
, Issue.4
, pp. 556-560
-
-
Nagamatsu, S.1
Ohara-Imaizumi, M.2
Nakamichi, Y.3
Aoyagi, K.4
Nishiwaki, C.5
-
11
-
-
84900005543
-
Liraglutide suppresses the plasma levels of active and des-acyl ghrelin independently of active glucagon-like peptide-1 levels in mice
-
184753 10.1155/2013/184753
-
Nonogaki K., Suzuki M., Liraglutide suppresses the plasma levels of active and des-acyl ghrelin independently of active glucagon-like peptide-1 levels in mice. ISRN Endocrinology 2013 2013 5 184753 10.1155/2013/184753
-
(2013)
ISRN Endocrinology
, vol.2013
, pp. 5
-
-
Nonogaki, K.1
Suzuki, M.2
-
12
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
2-s2.0-20444435873 10.1172/JCI23606
-
Kharitonenkov A., Shiyanova T. L., Koester A., Ford A. M., Micanovic R., Galbreath E. J., Sandusky G. E., Hammond L. J., Moyers J. S., Owens R. A., Gromada J., Brozinick J. T., Hawkins E. D., Wroblewski V. J., Li D.-S., Mehrbod F., Jaskunas S. R., Shanafelt A. B., FGF-21 as a novel metabolic regulator. The Journal of Clinical Investigation 2005 115 6 1627 1635 2-s2.0-20444435873 10.1172/JCI23606
-
(2005)
The Journal of Clinical Investigation
, vol.115
, Issue.6
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
Sandusky, G.E.7
Hammond, L.J.8
Moyers, J.S.9
Owens, R.A.10
Gromada, J.11
Brozinick, J.T.12
Hawkins, E.D.13
Wroblewski, V.J.14
Li, D.-S.15
Mehrbod, F.16
Jaskunas, S.R.17
Shanafelt, A.B.18
-
13
-
-
69249093921
-
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity
-
2-s2.0-69249093921 10.1210/en.2009-0221
-
Berglund E. D., Li C. Y., Bina H. A., Lynes S. E., Michael M. D., Shanafelt A. B., Kharitonenkov A., Wasserman D. H., Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity. Endocrinology 2009 150 9 4084 4093 2-s2.0-69249093921 10.1210/en.2009-0221
-
(2009)
Endocrinology
, vol.150
, Issue.9
, pp. 4084-4093
-
-
Berglund, E.D.1
Li, C.Y.2
Bina, H.A.3
Lynes, S.E.4
Michael, M.D.5
Shanafelt, A.B.6
Kharitonenkov, A.7
Wasserman, D.H.8
-
14
-
-
57349098220
-
Fibroblast growth factor 21 corrects obesity in mice
-
2-s2.0-57349098220 10.1210/en.2008-0816
-
Coskun T., Bina H. A., Schneider M. A., Dunbar J. D., Hu C. C., Chen Y., Moller D. E., Kharitonenkov A., Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 2008 149 12 6018 6027 2-s2.0-57349098220 10.1210/en.2008-0816
-
(2008)
Endocrinology
, vol.149
, Issue.12
, pp. 6018-6027
-
-
Coskun, T.1
Bina, H.A.2
Schneider, M.A.3
Dunbar, J.D.4
Hu, C.C.5
Chen, Y.6
Moller, D.E.7
Kharitonenkov, A.8
-
15
-
-
61649127208
-
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
-
2-s2.0-61649127208 10.2337/db08-0392
-
Xu J., Lloyd D. J., Hale C., Stanislaus S., Chen M., Sivits G., Vonderfecht S., Hecht R., Li Y.-S., Lindberg R. A., Chen J.-L., Jung D. Y., Zhang Z., Ko H.-J., Kim J. K., Véniant M. M., Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 2009 58 1 250 259 2-s2.0-61649127208 10.2337/db08-0392
-
(2009)
Diabetes
, vol.58
, Issue.1
, pp. 250-259
-
-
Xu, J.1
Lloyd, D.J.2
Hale, C.3
Stanislaus, S.4
Chen, M.5
Sivits, G.6
Vonderfecht, S.7
Hecht, R.8
Li, Y.-S.9
Lindberg, R.A.10
Chen, J.-L.11
Jung, D.Y.12
Zhang, Z.13
Ko, H.-J.14
Kim, J.K.15
Véniant, M.M.16
-
16
-
-
84869051421
-
Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance
-
e48392 10.1371/journal.pone.0048392
-
Yang M., Zhang L., Wang C., Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance. PLoS ONE 2012 7 11 e48392 10.1371/journal.pone.0048392
-
(2012)
PLoS ONE
, vol.7
, Issue.11
-
-
Yang, M.1
Zhang, L.2
Wang, C.3
-
17
-
-
45649085226
-
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
-
2-s2.0-45649085226 10.1016/j.cmet.2008.05.006
-
Inagaki T., Lin V. Y., Goetz R., Mohammadi M., Mangelsdorf D. J., Kliewer S. A., Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. Cell Metabolism 2008 8 1 77 83 2-s2.0-45649085226 10.1016/j.cmet.2008.05. 006
-
(2008)
Cell Metabolism
, vol.8
, Issue.1
, pp. 77-83
-
-
Inagaki, T.1
Lin, V.Y.2
Goetz, R.3
Mohammadi, M.4
Mangelsdorf, D.J.5
Kliewer, S.A.6
-
18
-
-
70350322694
-
Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis
-
2-s2.0-70350322694 10.1210/en.2009-0532
-
Badman M. K., Koester A., Flier J. S., Kharitonenkov A., Maratos-Flier E., Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis. Endocrinology 2009 150 11 4931 4940 2-s2.0-70350322694 10.1210/en.2009-0532
-
(2009)
Endocrinology
, vol.150
, Issue.11
, pp. 4931-4940
-
-
Badman, M.K.1
Koester, A.2
Flier, J.S.3
Kharitonenkov, A.4
Maratos-Flier, E.5
-
19
-
-
47949111205
-
Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor γ and altered metabolic states
-
2-s2.0-47949111205 10.1124/mol.108.044826
-
Muise E. S., Azzolina B., Kuo D. W., El-Sherbeini M., Tan Y., Yuan X., Mu J., Thompson J. R., Berger J. P., Wong K. K., Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor γ and altered metabolic states. Molecular Pharmacology 2008 74 2 403 412 2-s2.0-47949111205 10.1124/mol.108.044826
-
(2008)
Molecular Pharmacology
, vol.74
, Issue.2
, pp. 403-412
-
-
Muise, E.S.1
Azzolina, B.2
Kuo, D.W.3
El-Sherbeini, M.4
Tan, Y.5
Yuan, X.6
Mu, J.7
Thompson, J.R.8
Berger, J.P.9
Wong, K.K.10
-
20
-
-
84863012459
-
Fibroblast growth factor-21 regulates PPAR γ activity and the antidiabetic actions of thiazolidinediones
-
2-s2.0-84856713404 10.1016/j.cell.2011.11.062
-
Dutchak P. A., Katafuchi T., Bookout A. L., Choi J. H., Yu R. T., Mangelsdorf D. J., Kliewer S. A., Fibroblast growth factor-21 regulates PPAR γ activity and the antidiabetic actions of thiazolidinediones. Cell 2012 148 3 556 567 2-s2.0-84856713404 10.1016/j.cell.2011.11.062
-
(2012)
Cell
, vol.148
, Issue.3
, pp. 556-567
-
-
Dutchak, P.A.1
Katafuchi, T.2
Bookout, A.L.3
Choi, J.H.4
Yu, R.T.5
Mangelsdorf, D.J.6
Kliewer, S.A.7
-
21
-
-
84876542381
-
Fibroblast growth factor 21 mediates specific glucagon actions
-
10.2337/db12-1116
-
Habegger K. M., Stemmer K., Cheng C., Fibroblast growth factor 21 mediates specific glucagon actions. Diabetes 2013 62 5 1453 1463 10.2337/db12-1116
-
(2013)
Diabetes
, vol.62
, Issue.5
, pp. 1453-1463
-
-
Habegger, K.M.1
Stemmer, K.2
Cheng, C.3
-
22
-
-
84876558435
-
Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: A novel mechanism of glucagon-stimulated lipolysis?
-
10.1007/s00125-012-2803-y
-
Arafat A. M., Kaczmarek P., Skrzypski M., Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: a novel mechanism of glucagon-stimulated lipolysis? Diabetologia 2013 56 3 588 597 10.1007/s00125-012-2803-y
-
(2013)
Diabetologia
, vol.56
, Issue.3
, pp. 588-597
-
-
Arafat, A.M.1
Kaczmarek, P.2
Skrzypski, M.3
-
23
-
-
84878808238
-
Pharmacology, physiology, and mechanisms of incretin hormone action
-
Campbell J. E., Drucker D. J., Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metabolism 2013 17 6 819 837
-
(2013)
Cell Metabolism
, vol.17
, Issue.6
, pp. 819-837
-
-
Campbell, J.E.1
Drucker, D.J.2
|