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Volumn 9, Issue 12, 2014, Pages 1557-1569

An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training

Author keywords

450k arrays; DNA methylation; Environment; Epigenomics; Exercise; Integrative analysis; Lifestyle; Transcriptional network

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; CITRATE SYNTHASE; MYOCYTE ENHANCER FACTOR 2; MYOGENIC FACTOR; TRANSCRIPTION FACTOR ETS; TRANSCRIPTOME;

EID: 84922042142     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/15592294.2014.982445     Document Type: Article
Times cited : (178)

References (58)
  • 2
    • 34548371839 scopus 로고    scopus 로고
    • The Molecular Bases of Training Adaptation
    • PMID: 17722947
    • Coffey VG, Hawley JA. The Molecular Bases of Training Adaptation. Sports Med 2007; 37:737-63; PMID: 17722947; http://dx.doi.org/10.2165/00007256- 200737090-00001
    • (2007) Sports Med , vol.37 , pp. 737-763
    • Coffey, V.G.1    Hawley, J.A.2
  • 3
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: Islands, start sites, gene bodies and beyond
    • PMID:22641018
    • Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 2012; 13:484-92; PMID:22641018; http://dx.doi.org/ 10.1038/nrg3230
    • (2012) Nat Rev Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 4
    • 85027954125 scopus 로고    scopus 로고
    • DNA methylation profiling in the clinic: Applications and challenges
    • PMID:22945394
    • Heyn H, Esteller M. DNA methylation profiling in the clinic: applications and challenges. Nat Rev Genet 2012; 13:679-92; PMID:22945394; http://dx.doi.org/ 10.1038/nrg3270
    • (2012) Nat Rev Genet , vol.13 , pp. 679-692
    • Heyn, H.1    Esteller, M.2
  • 5
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • PMID:17320506
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128:683-92; PMID:17320506; http://dx.doi. org/10.1016/j.cell.2007.01.029
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 6
    • 40949093544 scopus 로고    scopus 로고
    • Epigenetics at the epicenter of modern medicine
    • PMID: 18349095
    • Feinberg AP. Epigenetics at the epicenter of modern medicine. JAMA 2008; 299:1345-50; PMID: 18349095; http://dx.doi.org/10.1001/jama.299.11. 1345
    • (2008) JAMA , vol.299 , pp. 1345-1350
    • Feinberg, A.P.1
  • 7
    • 84884784742 scopus 로고    scopus 로고
    • Age-associated epigenetic drift: Implications, and a case of epigenetic thrift?
    • PMID: 23918660
    • Teschendorff AE, West J, Beck S. Age-associated epigenetic drift: implications, and a case of epigenetic thrift? Human Molecular Genetics 2013; 22:R7-R15; PMID: 23918660; http://dx.doi.org/10.1093/hmg/ddt375
    • (2013) Human Molecular Genetics , vol.22 , pp. R7-R15
    • Teschendorff, A.E.1    West, J.2    Beck, S.3
  • 9
    • 84855956247 scopus 로고    scopus 로고
    • Epigenetics and the environment: Emerging patterns and implications
    • Feil R, Fraga MF. Epigenetics and the environment: emerging patterns and implications. Nat Rev Genet 2011; 13:97-109.
    • (2011) Nat Rev Genet , vol.13 , pp. 97-109
    • Feil, R.1    Fraga, M.F.2
  • 10
    • 84860006823 scopus 로고    scopus 로고
    • Dietary and Lifestyle Factors of DNA Methylation
    • Totowa, NJ: Humana Press
    • Lim U, Song M-A. Dietary and Lifestyle Factors of DNA Methylation. In: Methods in Molecular Biology. Totowa, NJ: Humana Press; 2012. pages 359-76. Available from.
    • (2012) Methods in Molecular Biology. , pp. 359-376
    • Lim, U.1    Song, M.-A.2
  • 13
    • 84870319843 scopus 로고    scopus 로고
    • Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes
    • PMID:23028138
    • Nitert MD, Dayeh T, Volkov P, Elgzyri T, Hall E, Nilsson E, Yang BT, Lang S, Parikh H, Wessman Y, et al. Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes. Diabetes 2012; 61:3322- 32; PMID:23028138; http://dx.doi.org/10.2337/ db11-1653
    • (2012) Diabetes , vol.61 , pp. 3322-3332
    • Nitert, M.D.1    Dayeh, T.2    Volkov, P.3    Elgzyri, T.4    Hall, E.5    Nilsson, E.6    Yang, B.T.7    Lang, S.8    Parikh, H.9    Wessman, Y.10
  • 15
    • 0001171879 scopus 로고    scopus 로고
    • Regulation of gene expression in skeletal muscle by contractile activity
    • Rowell LB, Shepherd JT, editors. Published for the American Physiological Society by Oxford University Press
    • Williams RS, Neufer PD. Regulation of gene expression in skeletal muscle by contractile activity. In: Rowell LB, Shepherd JT, editors. Exercise: regulation and integration of multiple systems. Published for the American Physiological Society by Oxford University Press; 1996. pages 1124-50.
    • (1996) Exercise: Regulation and integration of multiple systems. , pp. 1124-1150
    • Williams, R.S.1    Neufer, P.D.2
  • 19
    • 84874816208 scopus 로고    scopus 로고
    • DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes
    • PMID: 23497655
    • Aran D, Sabato S, Hellman A. DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes. Genome Biol 2013; 14:R21; PMID: 23497655; http://dx.doi.org/10.1186/gb-2013-14-3- r21
    • (2013) Genome Biol , vol.14
    • Aran, D.1    Sabato, S.2    Hellman, A.3
  • 21
    • 70450187836 scopus 로고    scopus 로고
    • Regulation of angiogenesis by ETS transcription factors
    • PMID: 19909256
    • Randi AM, Sperone A, Dryden NH, Birdsey GM. Regulation of angiogenesis by ETS transcription factors. Biochem Soc Trans 2009; 37:1248-53; PMID: 19909256; http://dx.doi.org/10.1042/BST0371248
    • (2009) Biochem Soc Trans , vol.37 , pp. 1248-1253
    • Randi, A.M.1    Sperone, A.2    Dryden, N.H.3    Birdsey, G.M.4
  • 22
    • 0031569417 scopus 로고    scopus 로고
    • Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP)
    • PMID: 9073519
    • Chew A, Buck EA, Peretz S, Sirugo G, Rinaldo P, Isaya G. Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP). Genomics 1997; 40:493-6; PMID: 9073519; http://dx.doi.org/10.1006/geno.1996.4586
    • (1997) Genomics , vol.40 , pp. 493-496
    • Chew, A.1    Buck, E.A.2    Peretz, S.3    Sirugo, G.4    Rinaldo, P.5    Isaya, G.6
  • 23
    • 84870389491 scopus 로고    scopus 로고
    • GRK5 ablation contributes to insulin resistance
    • PMID:23111327
    • Wang L, Shen M, Wang F, Ma L. GRK5 ablation contributes to insulin resistance. Biochem Biophys Res Commun 2012; 429:99-104; PMID:23111327; http:// dx.doi.org/10.1016/j.bbrc.2012.10.077
    • (2012) Biochem Biophys Res Commun , vol.429 , pp. 99-104
    • Wang, L.1    Shen, M.2    Wang, F.3    Ma, L.4
  • 25
    • 79551632945 scopus 로고    scopus 로고
    • Bimodal distribution of RNA expression levels in human skeletal muscle tissue
    • PMID:21299892
    • Mason CC, Hanson RL, Ossowski V, Bian L, Baier LJ, Krakoff J, Bogardus C. Bimodal distribution of RNA expression levels in human skeletal muscle tissue. BMC Genomics 2011; 12:98; PMID:21299892; http://dx. doi.org/10.1186/1471-2164-12-98
    • (2011) BMC Genomics , vol.12 , pp. 98
    • Mason, C.C.1    Hanson, R.L.2    Ossowski, V.3    Bian, L.4    Baier, L.J.5    Krakoff, J.6    Bogardus, C.7
  • 26
    • 79960676667 scopus 로고    scopus 로고
    • Regulation of Adipocyte Differentiation by the Zinc Finger Protein ZNF638
    • PMID: 21602272
    • Meruvu S, Hugendubler L, Mueller E. Regulation of Adipocyte Differentiation by the Zinc Finger Protein ZNF638. J Biol Chem 2011; 286:26516-23; PMID: 21602272; http://dx.doi.org/10.1074/jbc.M110. 212506
    • (2011) J Biol Chem , vol.286 , pp. 26516-26523
    • Meruvu, S.1    Hugendubler, L.2    Mueller, E.3
  • 27
  • 28
    • 77953164300 scopus 로고    scopus 로고
    • Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans
    • PMID:20133430
    • Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, Jensen T, Keller P, Scheele C, Vollaard NBJ, Nielsen S, et al. Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol 2010; 108:1487-96; PMID:20133430; http://dx.doi.org/ 10.1152/japplphysiol.01295.2009
    • (2010) J Appl Physiol , vol.108 , pp. 1487-1496
    • Timmons, J.A.1    Knudsen, S.2    Rankinen, T.3    Koch, L.G.4    Sarzynski, M.5    Jensen, T.6    Keller, P.7    Scheele, C.8    Vollaard, N.B.J.9    Nielsen, S.10
  • 29
    • 79960556965 scopus 로고    scopus 로고
    • Epigenome- wide association studies for common human diseases
    • PMID: 21747404
    • Rakyan VK, Down TA, Balding DJ, Beck S. Epigenome- wide association studies for common human diseases. Nat Rev Genet 2011; 12:529-41; PMID: 21747404; http://dx.doi.org/10.1038/nrg3000
    • (2011) Nat Rev Genet , vol.12 , pp. 529-541
    • Rakyan, V.K.1    Down, T.A.2    Balding, D.J.3    Beck, S.4
  • 32
    • 81855169482 scopus 로고    scopus 로고
    • Vascular remodelling in human skeletal muscle
    • PMID: 22103498
    • Gustafsson T. Vascular remodelling in human skeletal muscle. Biochem Soc Trans 2011; 39:1628-32; PMID: 22103498; http://dx.doi.org/10.1042/BST20110720
    • (2011) Biochem Soc Trans , vol.39 , pp. 1628-1632
    • Gustafsson, T.1
  • 33
    • 77957932941 scopus 로고    scopus 로고
    • Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications
    • PMID:20852635
    • Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, et al. Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol 2010; 28:1097-105; PMID:20852635; http://dx.doi.org/ 10.1038/nbt.1682
    • (2010) Nat Biotechnol , vol.28 , pp. 1097-1105
    • Harris, R.A.1    Wang, T.2    Coarfa, C.3    Nagarajan, R.P.4    Hong, C.5    Downey, S.L.6    Johnson, B.E.7    Fouse, S.D.8    Delaney, A.9    Zhao, Y.10
  • 34
    • 78650058320 scopus 로고    scopus 로고
    • Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation
    • PMID:21045081
    • Robinson MD, Stirzaker C, Statham AL, Coolen MW, Song JZ, Nair SS, Strbenac D, Speed TP, Clark SJ. Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation. Genome Research 2010; 20:1719-29; PMID:21045081; http://dx.doi.org/ 10.1101/gr.110601.110
    • (2010) Genome Research , vol.20 , pp. 1719-1729
    • Robinson, M.D.1    Stirzaker, C.2    Statham, A.L.3    Coolen, M.W.4    Song, J.Z.5    Nair, S.S.6    Strbenac, D.7    Speed, T.P.8    Clark, S.J.9
  • 37
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • PMID:16517406
    • Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006; 3:187-97; PMID:16517406; http:// dx.doi.org/10.1016/j.cmet.2006.01.012
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 38
    • 84905259548 scopus 로고    scopus 로고
    • Negative regulation of HIF in skeletal muscle of elite endurance athletes: A tentative mechanism promoting oxidative metabolism
    • PMID:24898836
    • Lindholm ME, Fischer H, Poellinger L, Johnson RS, Gustafsson T, Sundberg CJ, Rundqvist H. Negative regulation of HIF in skeletal muscle of elite endurance athletes: a tentative mechanism promoting oxidative metabolism. Am J Physiol Regul Integr Comp Physiol 2014; 307:R248-55; PMID:24898836; http://dx.doi. org/10.1152/ajpregu.00036.2013
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.307 , pp. R248-R255
    • Lindholm, M.E.1    Fischer, H.2    Poellinger, L.3    Johnson, R.S.4    Gustafsson, T.5    Sundberg, C.J.6    Rundqvist, H.7
  • 40
    • 79960421165 scopus 로고    scopus 로고
    • Excitation-transcription coupling in skeletal muscle: The molecular pathways of exercise
    • PMID:21040371
    • Gundersen K. Excitation-transcription coupling in skeletal muscle: the molecular pathways of exercise. Biol Rev Camb Philos Soc 2011; 86:564-600; PMID:21040371; http://dx.doi.org/10.1111/j.1469- 185X.2010.00161.x
    • (2011) Biol Rev Camb Philos Soc , vol.86 , pp. 564-600
    • Gundersen, K.1
  • 41
    • 69249116960 scopus 로고    scopus 로고
    • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Coactivator- 1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD
    • PMID:19553684
    • Amat R, Planavila A, Chen SL, Iglesias R, Giralt M, Villarroya F. SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Coactivator- 1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. J Biol Chem 2009; 284:21872-80; PMID:19553684; http://dx.doi.org/ 10.1074/jbc.M109.022749
    • (2009) J Biol Chem , vol.284 , pp. 21872-21880
    • Amat, R.1    Planavila, A.2    Chen, S.L.3    Iglesias, R.4    Giralt, M.5    Villarroya, F.6
  • 42
    • 38049147787 scopus 로고    scopus 로고
    • MEF2: A central regulator of diverse developmental programs
    • PMID:17959722
    • Potthoff MJ, Olson EN. MEF2: a central regulator of diverse developmental programs. Development 2007; 134:4131-40; PMID:17959722; http://dx.doi.org/ 10.1242/dev.008367
    • (2007) Development , vol.134 , pp. 4131-4140
    • Potthoff, M.J.1    Olson, E.N.2
  • 43
    • 38049155825 scopus 로고    scopus 로고
    • Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
    • PMID:18185590
    • Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, Cui H. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008; 451:202-6; PMID:18185590; http://dx.doi.org/ 10.1038/nature06468
    • (2008) Nature , vol.451 , pp. 202-206
    • Yu, W.1    Gius, D.2    Onyango, P.3    Muldoon-Jacobs, K.4    Karp, J.5    Feinberg, A.P.6    Cui, H.7
  • 44
    • 58149218633 scopus 로고    scopus 로고
    • Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure
    • PMID:18997871
    • Fredriksson K, Tjäder I, Keller P, Petrovic N, Ahlman B, Scheele C, Wernerman J, Timmons JA, Rooyackers O. Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure. PLoS ONE 2008; 3:e3686; PMID:18997871; http://dx.doi.org/ 10.1371/journal.pone.0003686
    • (2008) PLoS ONE , vol.3
    • Fredriksson, K.1    Tjäder, I.2    Keller, P.3    Petrovic, N.4    Ahlman, B.5    Scheele, C.6    Wernerman, J.7    Timmons, J.A.8    Rooyackers, O.9
  • 45
    • 2342477730 scopus 로고    scopus 로고
    • Erralpha and Gabpa/b specify PGC-1alphadependent oxidative phosphorylation gene expression that is altered in diabetic muscle
    • PMID:15100410
    • Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, et al. Erralpha and Gabpa/b specify PGC-1alphadependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci USA 2004; 101:6570-5; PMID:15100410; http://dx. doi.org/10.1073/pnas.0401401101
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6570-6575
    • Mootha, V.K.1    Handschin, C.2    Arlow, D.3    Xie, X.4    St. Pierre, J.5    Sihag, S.6    Yang, W.7    Altshuler, D.8    Puigserver, P.9    Patterson, N.10
  • 46
    • 33751324537 scopus 로고    scopus 로고
    • Regulation of vascular inflammation and remodeling by ETS factors
    • PMID:17122446
    • Oettgen P. Regulation of vascular inflammation and remodeling by ETS factors. Circul Res 2006; 99:1159- 66; PMID:17122446; http://dx.doi.org/10.1161/01. RES.0000251056.85990.db
    • (2006) Circul Res , vol.99 , pp. 1159-1166
    • Oettgen, P.1
  • 47
    • 33645101422 scopus 로고    scopus 로고
    • Oligonucleotide microarray expression profiling: Human skeletal muscle phenotype and aerobic exercise training
    • PMID:16540428
    • Timmons JA, Sundberg CJ. Oligonucleotide microarray expression profiling: human skeletal muscle phenotype and aerobic exercise training. IUBMB Life 2006; 58:15-24; PMID:16540428; http://dx.doi.org/ 10.1080/15216540500507390
    • (2006) IUBMB Life , vol.58 , pp. 15-24
    • Timmons, J.A.1    Sundberg, C.J.2
  • 48
    • 34547641224 scopus 로고    scopus 로고
    • Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family
    • PMID: 17652178
    • Hollenhorst PC, Shah AA, Hopkins C, Graves BJ. Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev 2007; 21:1882-94; PMID: 17652178; http://dx.doi.org/10.1101/gad.1561707
    • (2007) Genes Dev , vol.21 , pp. 1882-1894
    • Hollenhorst, P.C.1    Shah, A.A.2    Hopkins, C.3    Graves, B.J.4
  • 49
    • 84863534997 scopus 로고    scopus 로고
    • Metabolic Regulation of Epigenetics
    • PMID:22768835
    • Lu C, Thompson CB. Metabolic Regulation of Epigenetics. Cell Metab 2012; 16:9-17; PMID:22768835; http://dx.doi.org/10.1016/j.cmet.2012.06.001
    • (2012) Cell Metab , vol.16 , pp. 9-17
    • Lu, C.1    Thompson, C.B.2
  • 52
    • 84872564830 scopus 로고    scopus 로고
    • A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
    • PMID:23175756
    • Teschendorff AE, Marabita F, Lechner M, Bartlett T, TegnEr J, Gomez-Cabrero D, Beck S. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics (Oxford, England) 2013; 29:189-96; PMID:23175756; http://dx.doi.org/10. 1093/bioinformatics/bts680
    • (2013) Bioinformatics (Oxford, England) , vol.29 , pp. 189-196
    • Teschendorff, A.E.1    Marabita, F.2    Lechner, M.3    Bartlett, T.4    TegnEr, J.5    Gomez-Cabrero, D.6    Beck, S.7
  • 53
    • 4544341015 scopus 로고    scopus 로고
    • Linear Models and Empirical BayesMethods for Assessing Differential Expression in Microarray Experiments
    • PMID:16646809
    • Smyth GK. Linear Models and Empirical BayesMethods for Assessing Differential Expression in Microarray Experiments. Stat Appl GenetMol Biol 2004; 3; PMID:16646809; http:// dx.doi.org/10.2202/1544-6115.1027
    • (2004) Stat Appl GenetMol Biol , vol.3
    • Smyth, G.K.1
  • 54
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • PMID:19910308
    • Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics (Oxford, England) 2010; 26:139-40; PMID:19910308; http://dx. doi.org/10.1093/bioinformatics/btp616
    • (2010) Bioinformatics (Oxford, England) , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 55
    • 77953212372 scopus 로고    scopus 로고
    • Gene ontology analysis for RNA-seq: Accounting for selection bias
    • PMID:20132535
    • Young MD, Wakefield MJ, Smyth GK, Oshlack A. Gene ontology analysis for RNA-seq: accounting for selection bias. Genome Biol 2010; 11:R14; PMID:20132535; http://dx.doi.org/10.1186/gb-2010- 11-2-r14
    • (2010) Genome Biol , vol.11
    • Young, M.D.1    Wakefield, M.J.2    Smyth, G.K.3    Oshlack, A.4
  • 56
    • 84880199410 scopus 로고    scopus 로고
    • Pathview: An R/Bioconductor package for pathway-based data integration and visualization
    • PMID:23740750
    • Luo W, Brouwer C. Pathview: an R/Bioconductor package for pathway-based data integration and visualization. Bioinformatics (Oxford, England) 2013; 29:1830-1; PMID:23740750; http://dx.doi.org/ 10.1093/bioinformatics/btt285
    • (2013) Bioinformatics (Oxford, England) , vol.29 , pp. 1830-1831
    • Luo, W.1    Brouwer, C.2
  • 57
    • 84907688003 scopus 로고    scopus 로고
    • The human skeletal muscle transcriptome: Sex differences, alternative splicing, and tissue homogeneity assessed with RNA sequencing
    • Lindholm ME, Huss M, Solnestam BW, Kjellqvist S, Lundeberg J, Sundberg CJ. The human skeletal muscle transcriptome: sex differences, alternative splicing, and tissue homogeneity assessed with RNA sequencing. FASEB J 2014.
    • (2014) FASEB J
    • Lindholm, M.E.1    Huss, M.2    Solnestam, B.W.3    Kjellqvist, S.4    Lundeberg, J.5    Sundberg, C.J.6
  • 58


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