메뉴 건너뛰기




Volumn 233, Issue 1, 2015, Pages 165-173

Epigenetic modulation of Cdk5 contributes to memory deficiency induced by amyloid fibrils

Author keywords

Amyloid fibrils; Cyclin dependent kinase 5; Epigenetic; Memory deficiency; Synaptic plasticity; Tau

Indexed keywords

AMYLOID; BISULFITE; CYCLIN DEPENDENT KINASE 5; CYTOSINE; HISTONE H3; MESSENGER RNA; ROSCOVITINE; TAU PROTEIN;

EID: 84922005355     PISSN: 00144819     EISSN: 14321106     Source Type: Journal    
DOI: 10.1007/s00221-014-4100-0     Document Type: Article
Times cited : (19)

References (33)
  • 1
    • 84877927154 scopus 로고    scopus 로고
    • Epigenetics: a novel therapeutic approach for the treatment of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3sXmvVWjt7k%3D, PID: 23562602
    • Adwan L, Zawia NH (2013) Epigenetics: a novel therapeutic approach for the treatment of Alzheimer’s disease. Pharmacol Ther 139:41–50. doi:10.1016/j.pharmthera.2013.03.010
    • (2013) Pharmacol Ther , vol.139 , pp. 41-50
    • Adwan, L.1    Zawia, N.H.2
  • 2
    • 77955282380 scopus 로고    scopus 로고
    • Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3cXps1Wku70%3D, PID: 20538041
    • Ahmed T, Enam SA, Gilani AH (2010) Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer’s disease. Neuroscience 169:1296–1306. doi:10.1016/j.neuroscience.2010.05.078
    • (2010) Neuroscience , vol.169 , pp. 1296-1306
    • Ahmed, T.1    Enam, S.A.2    Gilani, A.H.3
  • 3
    • 6044240725 scopus 로고    scopus 로고
    • Beta-sheet breaker peptide prevents Abeta-induced spatial memory impairments with partial reduction of amyloid deposits
    • COI: 1:CAS:528:DC%2BD2cXnvVKmsLw%3D, PID: 15098004
    • Chacon MA, Barria MI, Soto C, Inestrosa NC (2004) Beta-sheet breaker peptide prevents Abeta-induced spatial memory impairments with partial reduction of amyloid deposits. Mol Psychiatry 9:953–961. doi:10.1038/sj.mp.4001516
    • (2004) Mol Psychiatry , vol.9 , pp. 953-961
    • Chacon, M.A.1    Barria, M.I.2    Soto, C.3    Inestrosa, N.C.4
  • 4
    • 84857781607 scopus 로고    scopus 로고
    • Cdk5: a multifaceted kinase in neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BC38XjsVCgsbg%3D, PID: 22189166
    • Cheung ZH, Ip NY (2012) Cdk5: a multifaceted kinase in neurodegenerative diseases. Trends Cell Biol 22:169–175. doi:10.1016/j.tcb.2011.11.003
    • (2012) Trends Cell Biol , vol.22 , pp. 169-175
    • Cheung, Z.H.1    Ip, N.Y.2
  • 5
    • 33645962807 scopus 로고    scopus 로고
    • Synaptic roles of Cdk5: implications in higher cognitive functions and neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BD28XjslyqtLk%3D, PID: 16600851
    • Cheung ZH, Fu AK, Ip NY (2006) Synaptic roles of Cdk5: implications in higher cognitive functions and neurodegenerative diseases. Neuron 50:13–18. doi:10.1016/j.neuron.2006.02.024
    • (2006) Neuron , vol.50 , pp. 13-18
    • Cheung, Z.H.1    Fu, A.K.2    Ip, N.Y.3
  • 6
    • 0345119031 scopus 로고    scopus 로고
    • Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression
    • COI: 1:CAS:528:DC%2BD3sXptVylu7g%3D, PID: 14642282
    • Colledge M et al (2003) Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron 40:595–607
    • (2003) Neuron , vol.40 , pp. 595-607
    • Colledge, M.1
  • 7
    • 84903362440 scopus 로고    scopus 로고
    • Global changes in DNA methylation and hydroxymethylation in Alzheimer’s disease human brain
    • COI: 1:CAS:528:DC%2BC2cXjtlCktA%3D%3D, PID: 24387984
    • Coppieters N, Dieriks BV, Lill C, Faull RL, Curtis MA, Dragunow M (2014) Global changes in DNA methylation and hydroxymethylation in Alzheimer’s disease human brain. Neurobiol Aging 35:1334–1344. doi:10.1016/j.neurobiolaging.2013.11.031
    • (2014) Neurobiol Aging , vol.35 , pp. 1334-1344
    • Coppieters, N.1    Dieriks, B.V.2    Lill, C.3    Faull, R.L.4    Curtis, M.A.5    Dragunow, M.6
  • 8
    • 4444262625 scopus 로고    scopus 로고
    • Cdk5 deregulation in the pathogenesis of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD2cXntlGhur0%3D, PID: 15350898
    • Cruz JC, Tsai LH (2004) Cdk5 deregulation in the pathogenesis of Alzheimer’s disease. Trends Mol Med 10:452–458. doi:10.1016/j.molmed.2004.07.001
    • (2004) Trends Mol Med , vol.10 , pp. 452-458
    • Cruz, J.C.1    Tsai, L.H.2
  • 9
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • COI: 1:CAS:528:DC%2BC3cXjtFynur8%3D, PID: 20228804
    • Feng J et al (2010) Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 13:423–430. doi:10.1038/nn.2514
    • (2010) Nat Neurosci , vol.13 , pp. 423-430
    • Feng, J.1
  • 10
    • 0034329543 scopus 로고    scopus 로고
    • Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants
    • COI: 1:CAS:528:DC%2BD3cXotFajtbY%3D, PID: 11054815
    • Flaherty DB, Soria JP, Tomasiewicz HG, Wood JG (2000) Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. J Neurosci Res 62:463–472. doi:10.1002/1097-4547(20001101)62:3<463:AID-JNR16>3.0.CO;2-7
    • (2000) J Neurosci Res , vol.62 , pp. 463-472
    • Flaherty, D.B.1    Soria, J.P.2    Tomasiewicz, H.G.3    Wood, J.G.4
  • 11
    • 79955622702 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression in physiological and pathological brain processes
    • COI: 1:CAS:528:DC%2BC3MXns1Cms70%3D, PID: 21527733
    • Graff J, Kim D, Dobbin MM, Tsai LH (2011) Epigenetic regulation of gene expression in physiological and pathological brain processes. Physiol Rev 91:603–649. doi:10.1152/physrev.00012.2010
    • (2011) Physiol Rev , vol.91 , pp. 603-649
    • Graff, J.1    Kim, D.2    Dobbin, M.M.3    Tsai, L.H.4
  • 12
    • 84862777943 scopus 로고    scopus 로고
    • An epigenetic blockade of cognitive functions in the neurodegenerating brain
    • PID: 22388814
    • Graff J et al (2012) An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 483:222–226. doi:10.1038/nature10849
    • (2012) Nature , vol.483 , pp. 222-226
    • Graff, J.1
  • 13
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • COI: 1:CAS:528:DC%2BD1MXlsF2ltro%3D, PID: 19424149
    • Guan JS et al (2009) HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459:55–60. doi:10.1038/nature07925
    • (2009) Nature , vol.459 , pp. 55-60
    • Guan, J.S.1
  • 14
    • 84868201684 scopus 로고    scopus 로고
    • TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory
    • COI: 1:CAS:528:DC%2BC38XhsV2rsbbO, PID: 23064382
    • Lai KO et al (2012) TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory. Nat Neurosci 15:1506–1515. doi:10.1038/nn.3237
    • (2012) Nat Neurosci , vol.15 , pp. 1506-1515
    • Lai, K.O.1
  • 15
    • 0032988741 scopus 로고    scopus 로고
    • Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain
    • COI: 1:CAS:528:DyaK1MXjsVSlt78%3D, PID: 10413323
    • Lee KY, Clark AW, Rosales JL, Chapman K, Fung T, Johnston RN (1999) Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain. Neurosci Res 34:21–29
    • (1999) Neurosci Res , vol.34 , pp. 21-29
    • Lee, K.Y.1    Clark, A.W.2    Rosales, J.L.3    Chapman, K.4    Fung, T.5    Johnston, R.N.6
  • 16
    • 84899477325 scopus 로고    scopus 로고
    • Acetylation of cyclin-dependent kinase 5 is mediated by GCN5
    • COI: 1:CAS:528:DC%2BC2cXmtVWrtL4%3D, PID: 24704205
    • Lee J, Yun N, Kim C, Song MY, Park KS, Oh YJ (2014) Acetylation of cyclin-dependent kinase 5 is mediated by GCN5. Biochem Biophys Res Commun 447:121–127. doi:10.1016/j.bbrc.2014.03.118
    • (2014) Biochem Biophys Res Commun , vol.447 , pp. 121-127
    • Lee, J.1    Yun, N.2    Kim, C.3    Song, M.Y.4    Park, K.S.5    Oh, Y.J.6
  • 17
    • 84891860126 scopus 로고    scopus 로고
    • Transcriptional activation of mina by sp1/3 factors
    • PID: 24324617
    • Lian S et al (2013) Transcriptional activation of mina by sp1/3 factors. PLoS one 8:e80638. doi:10.1371/journal.pone.0080638
    • (2013) PLoS one , vol.8 , pp. e80638
    • Lian, S.1
  • 18
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • COI: 1:CAS:528:DC%2BD1cXht1ymt7vI, PID: 18923034
    • Lubin FD, Roth TL, Sweatt JD (2008) Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 28:10576–10586. doi:10.1523/JNEUROSCI.1786-08.2008
    • (2008) J Neurosci , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 20
    • 68949096744 scopus 로고    scopus 로고
    • Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer’s disease
    • PID: 19672297
    • Mastroeni D, McKee A, Grover A, Rogers J, Coleman PD (2009) Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer’s disease. PloS one 4:e6617. doi:10.1371/journal.pone.0006617
    • (2009) PloS one , vol.4 , pp. e6617
    • Mastroeni, D.1    McKee, A.2    Grover, A.3    Rogers, J.4    Coleman, P.D.5
  • 21
    • 84859108475 scopus 로고    scopus 로고
    • Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning
    • COI: 1:CAS:528:DC%2BC38XjtVWmu7w%3D, PID: 22349397
    • Pascual M, Do Couto BR, Alfonso-Loeches S, Aguilar MA, Rodriguez-Arias M, Guerri C (2012) Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning. Neuropharmacology 62:2309–2319. doi:10.1016/j.neuropharm.2012.01.011
    • (2012) Neuropharmacology , vol.62 , pp. 2309-2319
    • Pascual, M.1    Do Couto, B.R.2    Alfonso-Loeches, S.3    Aguilar, M.A.4    Rodriguez-Arias, M.5    Guerri, C.6
  • 22
    • 84870493318 scopus 로고    scopus 로고
    • Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP
    • COI: 1:CAS:528:DC%2BC3sXmsVCltLs%3D, PID: 23166293
    • Pita-Almenar JD, Zou S, Colbert CM, Eskin A (2012) Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learn Mem 19:615–626. doi:10.1101/lm.023259.111
    • (2012) Learn Mem , vol.19 , pp. 615-626
    • Pita-Almenar, J.D.1    Zou, S.2    Colbert, C.M.3    Eskin, A.4
  • 23
    • 84892159781 scopus 로고    scopus 로고
    • Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression
    • COI: 1:CAS:528:DC%2BC3sXhtlGjurzK, PID: 23977113
    • Provencal N et al (2013) Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression. PLoS one 8:e71691. doi:10.1371/journal.pone.0071691
    • (2013) PLoS one , vol.8 , pp. e71691
    • Provencal, N.1
  • 24
    • 79960894797 scopus 로고    scopus 로고
    • CDK5 is essential for soluble amyloid beta-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton
    • COI: 1:CAS:528:DC%2BC3MXhtVyksbfI, PID: 21829588
    • Roselli F, Livrea P, Almeida OF (2011) CDK5 is essential for soluble amyloid beta-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton. PLoS one 6:e23097. doi:10.1371/journal.pone.0023097
    • (2011) PLoS one , vol.6 , pp. e23097
    • Roselli, F.1    Livrea, P.2    Almeida, O.F.3
  • 25
    • 84898865628 scopus 로고    scopus 로고
    • Epigenetic modifications in the nervous system and their impact upon cognitive impairments
    • COI: 1:CAS:528:DC%2BC2cXivF2qs7o%3D, PID: 24495398
    • Rudenko A, Tsai LH (2014) Epigenetic modifications in the nervous system and their impact upon cognitive impairments. Neuropharmacology 80:70–82. doi:10.1016/j.neuropharm.2014.01.043
    • (2014) Neuropharmacology , vol.80 , pp. 70-82
    • Rudenko, A.1    Tsai, L.H.2
  • 26
    • 84870821482 scopus 로고    scopus 로고
    • UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression
    • COI: 1:CAS:528:DC%2BC38XhslyntL%2FJ, PID: 22286757
    • Sabatino L et al (2012) UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression. Oncogene 31:5061–5072. doi:10.1038/onc.2012.3
    • (2012) Oncogene , vol.31 , pp. 5061-5072
    • Sabatino, L.1
  • 27
    • 79551510136 scopus 로고    scopus 로고
    • Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation
    • COI: 1:CAS:528:DC%2BC3MXhvFGkurs%3D, PID: 21289177
    • Shipton OA et al (2011) Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation. J Neurosci 31:1688–1692. doi:10.1523/JNEUROSCI.2610-10.2011
    • (2011) J Neurosci , vol.31 , pp. 1688-1692
    • Shipton, O.A.1
  • 28
    • 84893958405 scopus 로고    scopus 로고
    • Dentate gyrus mediates cognitive function in the Ts65Dn/DnJ mouse model of down syndrome
    • Smith GK, Kesner RP, Korenberg JR (2013) Dentate gyrus mediates cognitive function in the Ts65Dn/DnJ mouse model of down syndrome. Hippocampus. doi:10.1002/hipo.22229
    • (2013) Hippocampus
    • Smith, G.K.1    Kesner, R.P.2    Korenberg, J.R.3
  • 29
    • 0034595872 scopus 로고    scopus 로고
    • Interaction of neuronal Cdc2-like protein kinase with microtubule-associated protein tau
    • COI: 1:CAS:528:DC%2BD3cXjvFCnurc%3D, PID: 10749861
    • Sobue K, Agarwal-Mawal A, Li W, Sun W, Miura Y, Paudel HK (2000) Interaction of neuronal Cdc2-like protein kinase with microtubule-associated protein tau. J Biol Chem 275:16673–16680. doi:10.1074/jbc.M000784200
    • (2000) J Biol Chem , vol.275 , pp. 16673-16680
    • Sobue, K.1    Agarwal-Mawal, A.2    Li, W.3    Sun, W.4    Miura, Y.5    Paudel, H.K.6
  • 30
    • 84868549261 scopus 로고    scopus 로고
    • Mercaptoacetamide-based class II HDAC inhibitor lowers Abeta levels and improves learning and memory in a mouse model of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3sXhvFWisw%3D%3D, PID: 23063601
    • Sung YM et al (2013) Mercaptoacetamide-based class II HDAC inhibitor lowers Abeta levels and improves learning and memory in a mouse model of Alzheimer’s disease. Exp Neurol 239:192–201. doi:10.1016/j.expneurol.2012.10.005
    • (2013) Exp Neurol , vol.239 , pp. 192-201
    • Sung, Y.M.1
  • 31
    • 84896690701 scopus 로고    scopus 로고
    • Mice with Deficient BK Channel Function Show Impaired Prepulse Inhibition and Spatial Learning, but Normal Working and Spatial Reference Memory
    • PID: 24303038
    • Typlt M, Mirkowski M, Azzopardi E, Ruettiger L, Ruth P, Schmid S (2013) Mice with Deficient BK Channel Function Show Impaired Prepulse Inhibition and Spatial Learning, but Normal Working and Spatial Reference Memory. PLoS one 8:e81270. doi:10.1371/journal.pone.0081270
    • (2013) PLoS one , vol.8 , pp. e81270
    • Typlt, M.1    Mirkowski, M.2    Azzopardi, E.3    Ruettiger, L.4    Ruth, P.5    Schmid, S.6
  • 32
    • 84895489518 scopus 로고    scopus 로고
    • Epigenetic dysregulation in Alzheimer’s disease: cause or consequence?
    • PID: 24579941
    • van den Hove DL, Kenis G, Rutten BP (2014) Epigenetic dysregulation in Alzheimer’s disease: cause or consequence? Epigenomics 6:9–11. doi:10.2217/epi.13.84
    • (2014) Epigenomics , vol.6 , pp. 9-11
    • van den Hove, D.L.1    Kenis, G.2    Rutten, B.P.3
  • 33
    • 77956587739 scopus 로고    scopus 로고
    • Abeta oligomers cause localized Ca(2 +) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines
    • COI: 1:CAS:528:DC%2BC3cXhtF2qsLnK, PID: 20826658
    • Zempel H, Thies E, Mandelkow E, Mandelkow EM (2010) Abeta oligomers cause localized Ca(2 +) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci 30:11938–11950. doi:10.1523/JNEUROSCI.2357-10.2010
    • (2010) J Neurosci , vol.30 , pp. 11938-11950
    • Zempel, H.1    Thies, E.2    Mandelkow, E.3    Mandelkow, E.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.