Melatonin Antagonizes Mn-Induced Oxidative Injury Through the Activation of Keap1–Nrf2–ARE Signaling Pathway in the Striatum of Mice

Neurotoxicity Research

Volumn 27, Issue 2, 2015, Pages 156-171

  Deng, Yu ^a   Zhu, Jiayu ^a   Mi, Chao ^b   Xu, Bin ^a   Jiao, Congcong ^a   Li, Yuehui ^a   Xu, Donghui ^a   Liu, Wei ^a   Xu, Zhaofa ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Department of Maternal and Child Health   (China)

Author keywords

Manganese; Melatonin; NF E2 related factor 2; Oxidative injury; Striatum

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MALONALDEHYDE; MANGANESE; MANGANESE CHLORIDE; MELATONIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; CHLORIDE; CYTOSKELETON PROTEIN; KEAP1 PROTEIN, MOUSE; MANGANESE DERIVATIVE; NFE2L2 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR DYSFUNCTION; MOUSE; NERVE CELL; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BODY WEIGHT; DRUG EFFECTS; LOCOMOTION; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; APOPTOSIS; BODY WEIGHT; CHLORIDES; CORPUS STRIATUM; CYTOSKELETAL PROTEINS; FEMALE; LOCOMOTION; MALE; MANGANESE COMPOUNDS; MELATONIN; MICE; NEURONS; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84921938403     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-014-9489-5     Document Type: Article

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