Consumption of sucrose, but not high fructose corn syrup, leads to increased adiposity and dyslipidaemia in the pregnant and lactating rat

Journal of Developmental Origins of Health and Disease

Volumn 6, Issue 1, 2014, Pages 38-46

  Toop, C R ^a   Muhlhausler, B S ^b   O'dea, K ^a   Gentili, S ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

adipose tissue; high fructose corn syrup; lactation; pregnancy; sucrose

Indexed keywords

CORN SYRUP; SUCROSE;

ANIMAL; BLOOD; COMPARATIVE STUDY; DRUG EFFECTS; DYSLIPIDEMIAS; FEMALE; LACTATION; MATERNAL NUTRITION; METABOLISM; OBESITY; PREGNANCY; PREGNANCY COMPLICATIONS; PSYCHOPHYSIOLOGY; RAT;

ADIPOSITY; ANIMALS; DYSLIPIDEMIAS; FEMALE; HIGH FRUCTOSE CORN SYRUP; LACTATION; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; OBESITY; PREGNANCY; PREGNANCY COMPLICATIONS; RATS; SATIETY RESPONSE; SUCROSE;

EID: 84921886023     PISSN: 20401744     EISSN: 20401752     Source Type: Journal    
DOI: 10.1017/S2040174414000610     Document Type: Article

References (52)

1. Danaei G, Finucane MM, Lu Y, et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2•7 million participants. Lancet. 2011; 378, 31-40
2. Johnson RK, Appel LJ, Brands M, et al. Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association. Circulation. 2009; 120, 1011-1020
3. Fung T, Malik V, Rexrode K, et al. Sweetened beverage consumption and risk of coronary heart disease in women. Am J Clin Nutr. 2009; 89, 1037-1042
4. Dhingra R, Sullivan L, Jacques PF, et al. Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation. 2007; 116, 480-488
5. Te Morenga L, Mallard S, Mann J. Dietary sugars and body weight: systematic review and meta-analyses of randomised controlled trials and cohort studies. BMJ. 2013; 346, e7492
6. Willett WC, Ludwig DS. Science souring on sugar. BMJ. 2013; 346, e8077
7. McLennan W, Podger A. National Nutrition Survey Nutrient Intakes and Physical Measurements 1995. 1998. Australian Bureau of Statistics: Canberra
8. Tappy L, Lê KA. Metabolic effects of fructose and the worldwide increase in obesity. Physiol Rev. 2010; 90, 23-46
9. Douard V, Ferraris RP. The role of fructose transporters in diseases linked to excessive fructose intake. J Physiol. 2013; 591, 401-414
10. Bizeau ME, Pagliassotti MJ. Hepatic adaptations to sucrose and fructose. Metabolism. 2005; 54, 1189-1201
11. Wei Y, Wang D, Topczewski F, Pagliassotti MJ. Fructosemediated stress signaling in the liver: implications for hepatic insulin resistance. J Nutr Biochem. 2007; 18, 1-9
12. Lustig RH. Fructose: it's 'alcohol without the buzz'. Adv Nutr. 2013; 4, 226-235
13. Regnault TRH, Gentili S, Sarr O, Toop CR, Sloboda DM. Fructose, pregnancy and later life impacts. Clin Exp Pharmacol Physiol. 2013; 40, 824-837
14. Bray G, Nielsen S, Popkin B. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr. 2004; 79, 537-543
15. Alfaradhi M, Ozanne S. Developmental programming in response to maternal over-nutrition. Front Genet. 2011; 2, 27
16. McMillen IC, Robinson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev. 2005; 85, 571-633
17. Chen LW,Hu FB, Yeung E,Willett W, ZhangCL. Prospective study of pre-gravid sugar-sweetened beverage consumption and the risk of gestational diabetes mellitus. Diabetes Care. 2009; 32, 2236-2241
18. Nelson SM, Matthews P, Poston L. Maternal metabolism and obesity: modifiable determinants of pregnancy outcome. Hum Reprod Update. 2010; 16, 255-275
19. Siega-Riz AM, Bodnar LM, Savitz DA. What are pregnant women eating?. Nutrient and food group differences by race. Am J Obstet Gynecol. 2002; 186, 480-486
20. Borgen I, Aamodt G, Harsem N, et al. Maternal sugar consumption and risk of preeclampsia in nulliparous Norwegian women. Eur J Clin Nutr. 2012; 66, 920-925
21. Englund-Ögge L, Brantsæter AL, Haugen M, et al. Association between intake of artificially sweetened and sugar-sweetened beverages and preterm delivery: a large prospective cohort study. Am J Clin Nutr. 2012; 96, 552-559
22. Phelan S, Hart C, Phipps M, et al. Maternal behaviors during pregnancy impact offspring obesity risk. Exp Diabetes Res. 2011; 2011, 9
23. Goran MI, Dumke K, Bouret SG, et al. The obesogenic effect of high fructose exposure during early development. Nat Rev Endocrinol. 2013; 9, 494-500
24. Sloboda DM, Li M, Patel R, et al. Early life exposure to fructose and offspring phenotype: implications for long term metabolic homeostasis. J Obes. 2014; 2014, 10
25. Vickers MH, Clayton ZE, Yap C, Sloboda DM. Maternal fructose intake during pregnancy and lactation alters placental growth and leads to sex-specific changes in fetal and neonatal endocrine function. Endocrinology. 2011; 152, 1378-1387
26. Mukai Y, Kumazawa M, Sato S. Fructose intake during pregnancy up-regulates the expression of maternal and fetal hepatic sterol regulatory element-binding protein-1c in rats. Endocrine. 2012; 44, 79-86
27. Mukai Y, Ozaki H, Serita Y, Sato S. Maternal fructose intake during pregnancy modulates hepatic and hypothalamic AMPactivated protein kinase signaling in gender-specific manner in offspring. Clin Exp Pharmacol Physiol. 2014; 41, 331-337
28. Rodríguez L, Panadero MI, Roglans N, et al. Fructose during pregnancy affects maternal and fetal leptin signaling. J Nutr Biochem. 2013; 24, 1709-1716
29. Samuelsson AM, Matthews PA, Jansen E, Taylor PD, Poston L. Sucrose feeding in mouse pregnancy leads to hypertension, and sex-linked obesity and insulin resistance in female offspring. Front Physiol. 2013; 4, 14
30. Jen KL, Rochon C, Zhong S, Whitcomb L. Fructose and sucrose feeding during pregnancy and lactation in rats changes maternal and pup fuel metabolism. J Nutr. 1991; 121, 1999-2005
31. Soria A, Chicco A, Mocchiutti N, et al. A sucrose-rich diet affects triglyceride metabolism differently in pregnant and nonpregnant rats and has negative effects on fetal growth. J Nutr. 1996; 126, 2481-2486
32. D'Alessandro ME, Oliva ME, Ferreira MR, et al. Sucrose-rich feeding during rat pregnancy-lactation and/or after weaning alters glucose and lipid metabolism in adult offspring. Clin Exp Pharmacol Physiol. 2012; 39, 623-629
33. D'Alessandro ME, Oliva ME, Fortino MA, Chicco A. Maternal sucrose-rich diet and fetal programming: changes in hepatic lipogenic and oxidative enzymes and glucose homeostasis in adult offspring. Food Funct. 2014; 5, 446-453
34. Taylor PD, Poston L. Developmental programming of obesity in mammals. Exp Physiol. 2007; 92, 287-298
35. Light HR, Tsanzi E, Gigliotti J, Morgan K, Tou JC. The type of caloric sweetener added to water influences weight gain, fat mass, and reproduction in growing Sprague-Dawley female rats. Exp Biol Med (Maywood). 2009; 234, 651-661
36. Sheludiakova A, Rooney K, Boakes R. Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat. Eur J Nutr. 2011; 51, 445-454
37. Bergheim I, Weber S, Vos M, et al. Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin. J Hepatol. 2008; 48, 983-992
38. Lindqvist A, Baelemans A, Erlanson-Albertsson C. Effects of sucrose, glucose and fructose on peripheral and central appetite signals. Regul Pept. 2008; 150, 26-32
39. Page K, Chan O, Arora J, et al. Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways. JAMA. 2013; 309, 63-70
40. Butte NF. Carbohydrate and lipid metabolism in pregnancy: normal compared with gestational diabetes mellitus. Am J Clin Nutr. 2000; 71, 1256S-1261SS.
41. Lee VM, Szepesi B, Hansen RJ. Absence of a Generalized Disaccharide Effect in Adult Female Rats. J Nutr. 1986; 116, 1555-1560
42. Michaelis OE, Nace CS, Szepesi B. Demonstration of a specific metabolic effect of dietary disaccharides in the rat. J Nutr. 1975; 105, 1186-1191
43. Soria A, D'Alessandro ME, Lombardo YB. Duration of feeding on a sucrose-rich diet determines metabolic and morphological changes in rat adipocytes. J Appl Physiol (1985). 2001; 91, 2109-2116
44. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006; 116, 1793-1801
45. Cahova M, Dankova H, Palenickova E, Papackova Z, Kazdova L. The opposite effects of high-sucrose and high-fat diet on fatty acid oxidation and very low density lipoprotein secretion in rat model of metabolic syndrome. J Nutr Metab. 2012; 2012, 757205
46. Su Q, Tsai J, Xu E, et al. Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology. 2009; 50, 77-84
47. Lustig RH. Fructose: metabolic, hedonic, and societal parallels with ethanol. J Am Diet Assoc. 2010; 110, 1307-1321
48. Crescenzo R, Bianco F, Coppola P, et al. The effect of high-fathigh- fructose diet on skeletal muscle mitochondrial energetics in adult rats. Eur J Nutr. 2014; doi:10.1007/s00394-014-0699-7
49. McMillen IC, MacLaughlin SM, Muhlhausler BS, et al. Developmental origins of adult health and disease: the role of periconceptional and foetal nutrition. Basic Clin Pharmacol Toxicol. 2008; 102, 82-89
50. Guo Y, Zhang X, Huang J, et al. Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. PLoS One. 2009; 4, e7641
51. Kinoshita T, Miyajima A. Cytokine regulation of liver development. Biochim Biophys Acta. 2002; 1592, 303-312
52. Mikkola HK, Orkin SH. The journey of developing hematopoietic stem cells. Development. 2006; 133, 3733-3744