메뉴 건너뛰기




Volumn 2, Issue JUNE, 2011, Pages

Developmental programming in response to maternal overnutrition

Author keywords

Developmental programming; Epigenetics; Maternal overnutrition; Obesity

Indexed keywords

ANIMALIA;

EID: 84860243027     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2011.00027     Document Type: Article
Times cited : (261)

References (127)
  • 2
    • 73749086869 scopus 로고    scopus 로고
    • Obesity induced by cafeteria feeding and pregnancy outcome in the rat
    • Akyol, A., Langley-Evans, S. C., and McMullen, S. (2009). Obesity induced by cafeteria feeding and pregnancy outcome in the rat. Br. J. Nutr. 102,1601-1610.
    • (2009) Br. J. Nutr. , vol.102 , pp. 1601-1610
    • Akyol, A.1    Langley-Evans, S.C.2    McMullen, S.3
  • 3
    • 33751191841 scopus 로고    scopus 로고
    • Role of neuropeptides in appetite regulation and obesity- a review
    • Arora,S.,and Anubhuti. (2006). Role of neuropeptides in appetite regulation and obesity- a review. Neuropeptides 40,375-401.
    • (2006) Neuropeptides , vol.40 , pp. 375-401
    • Arora, S.1    Anubhuti2
  • 4
    • 27144545771 scopus 로고    scopus 로고
    • Being big or growing fast: systematic review of size and growth in infancy and later obesity
    • Baird, J., Fisher, D., Lucas, P., Kleijnen, J., Roberts, H., and Law, C. (2005). Being big or growing fast: systematic review of size and growth in infancy and later obesity. BMJ 331, 929.
    • (2005) BMJ , vol.331 , pp. 929
    • Baird, J.1    Fisher, D.2    Lucas, P.3    Kleijnen, J.4    Roberts, H.5    Law, C.6
  • 5
    • 0027529974 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth
    • Barker, D. J., Hales, C. N., Fall, C. H., Osmond, C., Phipps, K., and Clark, P. M. (1993). Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36, 62-67.
    • (1993) Diabetologia , vol.36 , pp. 62-67
    • Barker, D.J.1    Hales, C.N.2    Fall, C.H.3    Osmond, C.4    Phipps, K.5    Clark, P.M.6
  • 6
    • 0022575555 scopus 로고
    • Diet and coronary heart disease in England and Wales during and after the second world war
    • Barker, D. J., and Osmond, C. (1986). Diet and coronary heart disease in England and Wales during and after the second world war. J. Epidemiol. Community Health 40, 37-44.
    • (1986) J. Epidemiol. Community Health , vol.40 , pp. 37-44
    • Barker, D.J.1    Osmond, C.2
  • 7
    • 34748883081 scopus 로고    scopus 로고
    • A maternal 'junk food' diet in pregnancy and lactation promotes an exacerbated taste for 'junk food' and a greater propensity for obesity in rat offspring
    • Bayol, S. A., Farrington, S. J., and Stick-land, N. C. (2007). A maternal 'junk food' diet in pregnancy and lactation promotes an exacerbated taste for 'junk food' and a greater propensity for obesity in rat offspring. Br. J. Nutr. 98,843-851.
    • (2007) Br. J. Nutr. , vol.98 , pp. 843-851
    • Bayol, S.A.1    Farrington, S.J.2    Stick-land, N.C.3
  • 8
    • 25844482016 scopus 로고    scopus 로고
    • A maternal cafeteria diet during gestation and lactation promotes adiposity and impairs skeletal muscle development and metabolism in rat offspring at weaning
    • Bayol, S. A., Simbi, B. H., and Stick-land, N. C. (2005). A maternal cafeteria diet during gestation and lactation promotes adiposity and impairs skeletal muscle development and metabolism in rat offspring at weaning. J. Physiol. 567(Pt 3), 951-961.
    • (2005) J. Physiol. , vol.567 , Issue.PART 3 , pp. 951-961
    • Bayol, S.A.1    Simbi, B.H.2    Stick-land, N.C.3
  • 9
    • 0025339808 scopus 로고
    • Hyperphagia in obesity is associated with a central peptidergic dysregulation in rats
    • Beck, B., Burlet, A., Nicolas, J. P., and Burlet, C. (1990). Hyperphagia in obesity is associated with a central peptidergic dysregulation in rats. J. Nutr. 120,806-811.
    • (1990) J. Nutr. , vol.120 , pp. 806-811
    • Beck, B.1    Burlet, A.2    Nicolas, J.P.3    Burlet, C.4
  • 10
    • 20344382306 scopus 로고    scopus 로고
    • Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus
    • Boney, C. M., Verma, A., Tucker, R., and Vohr, B. R. (2005). Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 115, e290-e296.
    • (2005) Pediatrics , vol.115
    • Boney, C.M.1    Verma, A.2    Tucker, R.3    Vohr, B.R.4
  • 11
    • 1642349297 scopus 로고    scopus 로고
    • Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice
    • Bouret, S. G., Draper, S. J., and Simerly, R. B. (2004). Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. J. Neurosci. 24, 2797-2805.
    • (2004) J. Neurosci. , vol.24 , pp. 2797-2805
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 14
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., and Burn, P. (1995). Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269, 546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 15
    • 33845520528 scopus 로고    scopus 로고
    • Differential gene expression and adiposity reduction induced by ascorbic acid supplementation in a cafeteria model of obesity
    • Campión, J., Milagro, F. I., Fernández, D., and Martínez, J. A. (2006). Differential gene expression and adiposity reduction induced by ascorbic acid supplementation in a cafeteria model of obesity. J. Physiol. Biochem. 62, 71-80.
    • (2006) J. Physiol. Biochem. , vol.62 , pp. 71-80
    • Campión, J.1    Milagro, F.I.2    Fernández, D.3    Martínez, J.A.4
  • 16
    • 79952003081 scopus 로고    scopus 로고
    • Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phe-notypes of progeny
    • Carmody,J.S.,Wan,P.,Accili,D.,Zeltser, L. M., and Leibel, R. L. (2010). Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phe-notypes of progeny. Obesity (Silver Spring) 19,492-499.
    • (2010) Obesity (Silver Spring) , vol.19 , pp. 492-499
    • Carmody, J.S.1    Wan, P.2    Accili, D.3    Zeltser, L.M.4    Leibel, R.L.5
  • 17
    • 77649272503 scopus 로고    scopus 로고
    • Distribution of leptin-sensitive cells in the postnatal and adult mouse brain
    • Caron, E., Sachot, C., Prevot, V., and Bouret, S. G. (2010). Distribution of leptin-sensitive cells in the postnatal and adult mouse brain. J. Comp. Neurol. 518,459-476.
    • (2010) J. Comp. Neurol. , vol.518 , pp. 459-476
    • Caron, E.1    Sachot, C.2    Prevot, V.3    Bouret, S.G.4
  • 20
    • 77949465525 scopus 로고    scopus 로고
    • Insulin receptor signaling in the development of neuronal structure and function
    • Chiu, S.-L., and Cline, H. T. (2010). Insulin receptor signaling in the development of neuronal structure and function. Neural Dev. 5, 7.
    • (2010) Neural Dev , vol.5 , pp. 7
    • Chiu, S.-L.1    Cline, H.T.2
  • 21
    • 65949099104 scopus 로고    scopus 로고
    • Developmental changes in hypothalamic leptin receptor: relationship with the postnatal leptin surge and energy balance neuropeptides in the postnatal rat
    • Cottrell, E. C., Cripps, R. L., Duncan, J. S., Barrett, P., Mercer, J. G., Herwig, A., and Ozanne, S. E. (2009). Developmental changes in hypothalamic leptin receptor: relationship with the postnatal leptin surge and energy balance neuropeptides in the postnatal rat. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296, R631-R639.
    • (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.296
    • Cottrell, E.C.1    Cripps, R.L.2    Duncan, J.S.3    Barrett, P.4    Mercer, J.G.5    Herwig, A.6    Ozanne, S.E.7
  • 23
    • 0036170673 scopus 로고    scopus 로고
    • Prenatal high protein exposure decreases energy expenditure and increases adiposity in young rats
    • Daenzer, M., Ortmann, S., Klaus, S., and Metges, C. C. (2002). Prenatal high protein exposure decreases energy expenditure and increases adiposity in young rats. J. Nutr. 132, 142-144.
    • (2002) J. Nutr. , vol.132 , pp. 142-144
    • Daenzer, M.1    Ortmann, S.2    Klaus, S.3    Metges, C.C.4
  • 24
    • 0035140336 scopus 로고    scopus 로고
    • The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation
    • Dandona, P., Mohanty, P., Ghanim, H., Aljada, A., Browne, R., Hamouda, W., Prabhala, A., Afzal, A., and Garg, R. (2001). The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. J. Clin. Endocrinol. Metab. 86, 355-362.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 355-362
    • Dandona, P.1    Mohanty, P.2    Ghanim, H.3    Aljada, A.4    Browne, R.5    Hamouda, W.6    Prabhala, A.7    Afzal, A.8    Garg, R.9
  • 25
    • 0037107412 scopus 로고    scopus 로고
    • Hypothalamic ventrome-dial and arcuate neurons of normal and postnatally overnourished rats differ in their responses to melanin-concentrating hormone
    • Davidowa, H., Li, Y., and Plagemann, A. (2002). Hypothalamic ventrome-dial and arcuate neurons of normal and postnatally overnourished rats differ in their responses to melanin-concentrating hormone. Regul. Pept. 108, 103-111.
    • (2002) Regul. Pept. , vol.108 , pp. 103-111
    • Davidowa, H.1    Li, Y.2    Plagemann, A.3
  • 26
    • 0042380214 scopus 로고    scopus 로고
    • Altered responses to orexigenic (AGRP, MCH) and anorexigenic (alpha-MSH CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats
    • Davidowa, H., Li, Y., and Plagemann, A. (2003). Altered responses to orexigenic (AGRP, MCH) and anorexigenic (alpha-MSH, CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats. Eur. J. Neurosci. 18,613-621.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 613-621
    • Davidowa, H.1    Li, Y.2    Plagemann, A.3
  • 27
    • 0034693444 scopus 로고    scopus 로고
    • Different responses of ven-tromedial hypothalamic neurons to leptin in normal and early postnatally overfed rats
    • Davidowa, H., and Plagemann, A. (2000). Different responses of ven-tromedial hypothalamic neurons to leptin in normal and early postnatally overfed rats. Neurosci. Lett. 293, 21-24.
    • (2000) Neurosci. Lett. , vol.293 , pp. 21-24
    • Davidowa, H.1    Plagemann, A.2
  • 28
    • 34247552309 scopus 로고    scopus 로고
    • Insulin resistance of hypothalamic arcuate neurons in neona-tally overfed rats
    • Davidowa, H., and Plagemann, A. (2007). Insulin resistance of hypothalamic arcuate neurons in neona-tally overfed rats. Neuroreport 18, 521-524.
    • (2007) Neuroreport , vol.18 , pp. 521-524
    • Davidowa, H.1    Plagemann, A.2
  • 30
    • 70350313230 scopus 로고    scopus 로고
    • Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice
    • Dunn, G. A., and Bale, T. L. (2009). Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology 150, 4999-5009.
    • (2009) Endocrinology , vol.150 , pp. 4999-5009
    • Dunn, G.A.1    Bale, T.L.2
  • 31
    • 79956301666 scopus 로고    scopus 로고
    • Maternal high-fat diet effects on third-generation female body size via the paternal lineage
    • Dunn, G. A., and Bale, T. L. (2011). Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology 152,2228-2236.
    • (2011) Endocrinology , vol.152 , pp. 2228-2236
    • Dunn, G.A.1    Bale, T.L.2
  • 34
    • 74549140993 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults 1999-2008
    • Flegal, K. M., Carroll, M. D., Ogden, C. L., and Curtin, L. R. (2010). Prevalence and trends in obesity among US adults, 1999-2008. JAMA 303, 235-241.
    • (2010) JAMA , vol.303 , pp. 235-241
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Curtin, L.R.4
  • 35
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults 1999-2000
    • Flegal, K. M., Carroll, M. D., Ogden, C. L., and Johnson, C. L. (2002). Prevalence and trends in obesity among US adults, 1999-2000. JAMA 288, 1723-1727.
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Johnson, C.L.4
  • 37
    • 0017755140 scopus 로고
    • Are poor living conditions in childhood and adolescence an important risk factor for arteriosclerotic heart disease?
    • Forsdahl, A. (1977). Are poor living conditions in childhood and adolescence an important risk factor for arteriosclerotic heart disease? Br. J. Prev.Soc.Med. 31,91-95.
    • (1977) Br. J. Prev. Soc. Med. , vol.31 , pp. 91-95
    • Forsdahl, A.1
  • 39
    • 34548032087 scopus 로고    scopus 로고
    • Genome-wide association studies provide new insights into type 2 diabetes aetiology
    • Frayling, T. M. (2007). Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat. Rev. Genet. 8, 657-662.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 657-662
    • Frayling, T.M.1
  • 40
    • 72649100220 scopus 로고    scopus 로고
    • Appetite and reward Front
    • Fulton, S. (2010). Appetite and reward. Front. Neuroendocrinol. 31, 85-103.
    • (2010) Neuroendocrinol , vol.31 , pp. 85-103
    • Fulton, S.1
  • 43
    • 77957753702 scopus 로고    scopus 로고
    • Maternal high fat feeding and gestational dietary restriction: effects on offspring body weight, food intake and hypothalamic gene expression over three generations in mice
    • Giraudo, S. Q., Della-Fera, M. A., Proctor, L., Wickwire, K., Ambati, S., and Baile, C. A. (2010). Maternal high fat feeding and gestational dietary restriction: effects on offspring body weight, food intake and hypothalamic gene expression over three generations in mice. Pharmacol. Biochem. Behav. 97, 121-129.
    • (2010) Pharmacol. Biochem. Behav. , vol.97 , pp. 121-129
    • Giraudo, S.Q.1    Della-Fera, M.A.2    Proctor, L.3    Wickwire, K.4    Ambati, S.5    Baile, C.A.6
  • 46
    • 33748450150 scopus 로고    scopus 로고
    • Postnatal environment overrides genetic and prenatal factors influencing offspring obesity and insulin resistance
    • Gorski, J. N., Dunn-Meynell, A. A., Hartman, T. G., and Levin, B. E. (2006). Postnatal environment overrides genetic and prenatal factors influencing offspring obesity and insulin resistance. Am. J. Physiol. Regul. Integr. Comp. Physiol. 291, R768-R778.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.291
    • Gorski, J.N.1    Dunn-Meynell, A.A.2    Hartman, T.G.3    Levin, B.E.4
  • 48
    • 0026772772 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phe-notype hypothesis
    • Hales, C. N., and Barker, D. J. (1992). Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phe-notype hypothesis. Diabetologia 35, 595-601.
    • (1992) Diabetologia , vol.35 , pp. 595-601
    • Hales, C.N.1    Barker, D.J.2
  • 49
    • 0026008824 scopus 로고
    • Fetal and infant growth and impaired glucose tolerance at age 64
    • Hales, C. N., Barker, D. J., Clark, P. M., Cox, L. J., Fall, C., Osmond, C., and Winter, P. D. (1991). Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 303, 1019-1022.
    • (1991) BMJ , vol.303 , pp. 1019-1022
    • Hales, C.N.1    Barker, D.J.2    Clark, P.M.3    Cox, L.J.4    Fall, C.5    Osmond, C.6    Winter, P.D.7
  • 50
    • 24944475639 scopus 로고    scopus 로고
    • Long-term effect of maternal obesity on pancreatic beta-cells of offspring: reduced beta cell adaptation to high glucose and high-fat diet challenges in adult female mouse offspring
    • Han, J., Xu, J., Epstein, P. N., and Liu, Y. Q. (2005). Long-term effect of maternal obesity on pancreatic beta-cells of offspring: reduced beta cell adaptation to high glucose and high-fat diet challenges in adult female mouse offspring. Diabetologia 48, 1810-1818.
    • (2005) Diabetologia , vol.48 , pp. 1810-1818
    • Han, J.1    Xu, J.2    Epstein, P.N.3    Liu, Y.Q.4
  • 51
    • 23944452658 scopus 로고    scopus 로고
    • Duration of breastfeeding and risk of overweight: a meta-analysis
    • Harder, T., Bergmann, R., Kallischnigg, G.,and Plagemann,A. (2005). Duration of breastfeeding and risk of overweight: a meta-analysis. Am. J. Epidemiol. 162, 397-403.
    • (2005) Am. J. Epidemiol. , vol.162 , pp. 397-403
    • Harder, T.1    Bergmann, R.2    Kallischnigg, G.3    Plagemann, A.4
  • 52
    • 0031837952 scopus 로고    scopus 로고
    • Syndrome X-like alterations in adult female rats due to neonatal insulin treatment
    • Harder, T., Plagemann, A., Rohde, W., and Dörner, G. (1998). Syndrome X-like alterations in adult female rats due to neonatal insulin treatment. Metab. Clin. Exp. 47, 855-862.
    • (1998) Metab. Clin. Exp. , vol.47 , pp. 855-862
    • Harder, T.1    Plagemann, A.2    Rohde, W.3    Dörner, G.4
  • 53
    • 0028931724 scopus 로고
    • Increased adipose tis sue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil, G. S., Arner, P., Caro, J. E, Atkinson, R. L., and Spiegelman, B. M. (1995). Increased adipose tis sue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J. Clin. Invest. 95, 2409-2415.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.3    Atkinson, E.4    Spiegelman, R.L.B.M.5
  • 54
    • 60349113479 scopus 로고    scopus 로고
    • Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet
    • Howie, G. J., Sloboda, D. M., Kamal, T., and Vickers, M. H. (2009). Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet. J. Physiol. 587(Pt 4), 905-915.
    • (2009) J. Physiol. , vol.587 , Issue.PART 4 , pp. 905-915
    • Howie, G.J.1    Sloboda, D.M.2    Kamal, T.3    Vickers, M.H.4
  • 55
    • 77956316801 scopus 로고    scopus 로고
    • Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes
    • doi: 10.1371/journal.pone.0010074
    • Igosheva, N., Abramov, A. Y., Pos-ton, L., Eckert, J. J., Fleming, T. P., Duchen, M. R., and McConnell, J. (2010). Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes. PLoS ONE 5, e10074. doi: 10.1371/journal.pone.0010074
    • (2010) PLoS ONE , vol.5
    • Igosheva, N.1    Abramov, A.Y.2    Pos-ton, L.3    Eckert, J.J.4    Fleming, T.P.5    Duchen, M.R.6    McConnell, J.7
  • 56
    • 0036293591 scopus 로고    scopus 로고
    • Leptin signaling, adiposity, and energy balance
    • Jéquier, E. (2002). Leptin signaling, adiposity, and energy balance. Ann. N. Y.Acad. Sci. 967, 379-388.
    • (2002) Ann. N. Y.Acad. Sci. , vol.967 , pp. 379-388
    • Jéquier, E.1
  • 57
    • 57649238863 scopus 로고    scopus 로고
    • Fetal programming of glucose-insulin metabolism
    • Jones, R. H., and Ozanne, S. E. (2009). Fetal programming of glucose-insulin metabolism. Mol. Cell. Endocrinol. 297, 4-9.
    • (2009) Mol. Cell. Endocrinol. , vol.297 , pp. 4-9
    • Jones, R.H.1    Ozanne, S.E.2
  • 58
    • 27844564364 scopus 로고    scopus 로고
    • Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital
    • Kanagalingam, M. G., Forouhi, N. G., Greer, I. A., and Sattar, N. (2005). Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital. BJOG 112,1431-1433.
    • (2005) BJOG , vol.112 , pp. 1431-1433
    • Kanagalingam, M.G.1    Forouhi, N.G.2    Greer, I.A.3    Sattar, N.4
  • 60
    • 0034678677 scopus 로고    scopus 로고
    • ARC POMC mRNA and PVN alpha-MSH are lower in obese relative to lean zucker rats
    • Kim, E. M., O'Hare, E., Grace, M. K., Welch, C. C., Billington, C. J., and Levine, A. S. (2000). ARC POMC mRNA and PVN alpha-MSH are lower in obese relative to lean zucker rats. Brain Res. 862, 11-16.
    • (2000) Brain Res , vol.862 , pp. 11-16
    • Kim, E.M.1    O'Hare, E.2    Grace, M.K.3    Welch, C.C.4    Billington, C.J.5    Levine, A.S.6
  • 61
    • 67649958535 scopus 로고    scopus 로고
    • Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring
    • doi: 10.1371/jour-nal.pone.0005870
    • Kirk, S. L., Samuelsson, A.-M., Argen-ton, M., Dhonye, H., Kalamatianos, T., Poston, L., Taylor, P. D., and Coen,C.W (2009). Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring. PLoS ONE 4, e5870. doi: 10.1371/jour-nal.pone.0005870
    • (2009) PLoS ONE , vol.4
    • Kirk, S.L.1    Samuelsson, A.-M.2    Argen-ton, M.3    Dhonye, H.4    Kalamatianos, T.5    Poston, L.6    Taylor, P.D.7    Coen, C.W.8
  • 63
    • 33846278577 scopus 로고    scopus 로고
    • Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years
    • Kral, J. G., Biron, S., Simard, S., Hould, F.-S., Lebel, S., Marceau, S., and Marceau, P. (2006). Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years. Pediatrics 118, e1644-e1649.
    • (2006) Pediatrics , vol.118
    • Kral, J.G.1    Biron, S.2    Simard, S.3    Hould, F.-S.4    Lebel, S.5    Marceau, S.6    Marceau, P.7
  • 64
    • 0034876785 scopus 로고    scopus 로고
    • Family social class, maternal body mass index, childhood body mass index, and age at menarche as predictors of adult obesity
    • Laitinen, J., Power, C., and Järvelin, M. R. (2001). Family social class, maternal body mass index, childhood body mass index, and age at menarche as predictors of adult obesity. Am. J. Clin. Nutr. 74, 287-294.
    • (2001) Am. J. Clin. Nutr. , vol.74 , pp. 287-294
    • Laitinen, J.1    Power, C.2    Järvelin, M.R.3
  • 65
    • 0030825835 scopus 로고    scopus 로고
    • Child to adult body mass index in the 1958 British birth cohort: associations with parental obesity
    • Lake, J. K., Power, C., and Cole, T. J. (1997). Child to adult body mass index in the 1958 British birth cohort: associations with parental obesity. Arch. Dis. Child. 77, 376-381.
    • (1997) Arch. Dis. Child. , vol.77 , pp. 376-381
    • Lake, J.K.1    Power, C.2    Cole, T.J.3
  • 66
    • 33748328554 scopus 로고    scopus 로고
    • Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis
    • Levin, B. E. (2006). Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis. Philos. Trans. R. Soc. Lond. B Biol. Sci. 361, 1107-1121.
    • (2006) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.361 , pp. 1107-1121
    • Levin, B.E.1
  • 68
    • 79952604150 scopus 로고    scopus 로고
    • Maternal obesity eliminates the neonatal lamb plasma leptin peak
    • Long, N. M., Ford, S. P., and Nathanielsz, P. W. (2011). Maternal obesity eliminates the neonatal lamb plasma leptin peak. J. Physiol. 589(Pt 6), 1455-1462.
    • (2011) J. Physiol. , vol.589 , Issue.PART 6 , pp. 1455-1462
    • Long, N.M.1    Ford, S.P.2    Nathanielsz, P.W.3
  • 72
    • 58149520049 scopus 로고    scopus 로고
    • Effect of high-fat diet during gestation, lactation, or postweaning on physiological and behavioral indexes in borderline hypertensive rats
    • Mitra, A., Alvers, K. M., Crump, E. M., and Rowland, N. E. (2009). Effect of high-fat diet during gestation, lactation, or postweaning on physiological and behavioral indexes in borderline hypertensive rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296, R20-R28.
    • (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.296
    • Mitra, A.1    Alvers, K.M.2    Crump, E.M.3    Rowland, N.E.4
  • 73
    • 33846425019 scopus 로고    scopus 로고
    • Increased maternal nutrition stimulates peroxisome proliferator activated receptor-gamma, adiponectin, and leptin messenger ribonucleic acid expression in adipose tissue before birth
    • Muhlhausler, B. S., Duffield, J. A., and McMillen, I. C. (2007a). Increased maternal nutrition stimulates peroxisome proliferator activated receptor-gamma, adiponectin, and leptin messenger ribonucleic acid expression in adipose tissue before birth. Endocrinology 148, 878-885.
    • (2007) Endocrinology , vol.148 , pp. 878-885
    • Muhlhausler, B.S.1    Duffield, J.A.2    McMillen, I.C.3
  • 74
    • 36348998157 scopus 로고    scopus 로고
    • Increased maternal nutrition increases leptin expression in perirenal and subcutaneous adipose tissue in the postnatal lamb
    • Muhlhausler, B. S., Duffield, J. A., and McMillen, I. C. (2007b). Increased maternal nutrition increases leptin expression in perirenal and subcutaneous adipose tissue in the postnatal lamb. Endocrinology 148, 6157-6163.
    • (2007) Endocrinology , vol.148 , pp. 6157-6163
    • Muhlhausler, B.S.1    Duffield, J.A.2    McMillen, I.C.3
  • 75
    • 67349198118 scopus 로고    scopus 로고
    • Obesity in the UK: a review and comparative analysis of policies within the devolved administrations
    • Musingarimi, P. (2009). Obesity in the UK: a review and comparative analysis of policies within the devolved administrations. Health Policy 91, 10-16.
    • (2009) Health Policy , vol.91 , pp. 10-16
    • Musingarimi, P.1
  • 76
    • 77958596171 scopus 로고    scopus 로고
    • Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring
    • Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., and Morris, M. J. (2010). Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature 467, 963-966.
    • (2010) Nature , vol.467 , pp. 963-966
    • Ng, S.-F.1    Lin, R.C.Y.2    Laybutt, D.R.3    Barres, R.4    Owens, J.A.5    Morris, M.J.6
  • 78
    • 67349223615 scopus 로고    scopus 로고
    • Established diet-induced obesity in female rats leads to offspring hyperpha-gia, adiposity and insulin resistance
    • Nivoit, P., Morens, C., Van Assche, E A., Jansen, E., Poston, L., Remacle, C., and Reusens, B. (2009). Established diet-induced obesity in female rats leads to offspring hyperpha-gia, adiposity and insulin resistance. Diabetologia 52, 1133-1142.
    • (2009) Diabetologia , vol.52 , pp. 1133-1142
    • Nivoit, P.1    Morens, C.2    Van Assche, E.A.3    Jansen, E.4    Poston, L.5    Remacle, C.6    Reusens, B.7
  • 82
    • 33645020300 scopus 로고    scopus 로고
    • Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index
    • Ong, K. K., Emmett, P. M., Noble, S., Ness, A., and Dunger, D. B. (2006). Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index. Pediatrics 117, e503-e508.
    • (2006) Pediatrics , vol.117
    • Ong, K.K.1    Emmett, P.M.2    Noble, S.3    Ness, A.4    Dunger, D.B.5
  • 83
    • 79960187082 scopus 로고    scopus 로고
    • Maternal 'junk-food' feeding of rat dams alters food choices and development of the mesolim-bic reward pathway in the offspring
    • doi: 10.1096/fj. 10-178392. [Epub ahead of print]
    • Ong, Z. Y., and Muhlhausler, B. S. (2011). Maternal 'junk-food' feeding of rat dams alters food choices and development of the mesolim-bic reward pathway in the offspring. FASEBJ. doi: 10.1096/fj. 10-178392. [Epub ahead of print].
    • (2011) FASEB J.
    • Ong, Z.Y.1    Muhlhausler, B.S.2
  • 84
    • 70349627249 scopus 로고    scopus 로고
    • Maternal and postweaning diet interaction alters hypothalamic gene expression and mo dulates response to a high-fat diet in male offspring
    • Page, K. C., Malik, R. E., Ripple, J. A., and Anday, E. K. (2009). Maternal and postweaning diet interaction alters hypothalamic gene expression and mo dulates response to a high-fat diet in male offspring. Am. J. Phys-iol. Regul. Integr. Comp. Physiol. 297, R1049-R1057.
    • (2009) Am. J. Phys-iol. Regul. Integr. Comp. Physiol. , vol.297
    • Page, K.C.1    Malik, R.E.2    Ripple, J.A.3    Anday, E.K.4
  • 85
    • 77956046109 scopus 로고    scopus 로고
    • Large litter rearing enhances leptin sensitivity and protects selectively bred diet-induced obese rats from becoming obese
    • Patterson, C. M., Bouret, S. G., Park, S., Irani, B. G., Dunn-Meynell, A. A., and Levin, B. E. (2010). Large litter rearing enhances leptin sensitivity and protects selectively bred diet-induced obese rats from becoming obese. Endocrinology 151, 4270-4279.
    • (2010) Endocrinology , vol.151 , pp. 4270-4279
    • Patterson, C.M.1    Bouret, S.G.2    Park, S.3    Irani, B.G.4    Dunn-Meynell, A.A.5    Levin, B.E.6
  • 86
    • 34547396431 scopus 로고    scopus 로고
    • The intake of physiological doses of leptin during lactation in rats prevents obesity in later life
    • Picó, C., Oliver, P., Sánchez, J., Miralles, O., Caimari,A.,Priego, T., andPalou, A. (2007). The intake of physiological doses of leptin during lactation in rats prevents obesity in later life. Int. J. Obes. (Lond), 31, 1199-1209.
    • (2007) Int. J. Obes. (Lond) , vol.31 , pp. 1199-1209
    • Picó, C.1    Oliver, P.2    Sánchez, J.3    Miralles, O.4    Caimari, A.5    Priego, T.6    Palou, A.7
  • 88
    • 0033620893 scopus 로고    scopus 로고
    • Perinatal elevation of hypothalamic insulin, acquired malformation of hypothalamic galaninergic neurons, and syndrome x-like alterations in adulthood of neonatally overfed rats
    • Plagemann, A., Harder, T., Rake, A., Voits, M., Fink, H., Rohde, W., and Dörner, G. (1999). Perinatal elevation of hypothalamic insulin, acquired malformation of hypothalamic galaninergic neurons, and syndrome x-like alterations in adulthood of neonatally overfed rats. Brain Res. 836, 146-155.
    • (1999) Brain Res. , vol.836 , pp. 146-155
    • Plagemann, A.1    Harder, T.2    Rake, A.3    Voits, M.4    Fink, H.5    Rohde, W.6    Dörner, G.7
  • 89
    • 0026786577 scopus 로고
    • Obesity and enhanced diabetes and cardiovascular risk in adult rats due to early postnatal overfeeding
    • Plagemann, A., Heidrich, I., Götz, F., Rohde, W., and Dörner, G. (1992). Obesity and enhanced diabetes and cardiovascular risk in adult rats due to early postnatal overfeeding. Exp. Clin. Endocrinol. 99, 154-158.
    • (1992) Exp. Clin. Endocrinol. , vol.99 , pp. 154-158
    • Plagemann, A.1    Heidrich, I.2    Götz, F.3    Rohde, W.4    Dörner, G.5
  • 91
    • 0036892158 scopus 로고    scopus 로고
    • Leptin regulates appetite-related neuropeptides in the hypo-thalamus of developing rats without affecting food intake
    • Proulx, K., Richard, D., and Walker, C.-D. (2002). Leptin regulates appetite-related neuropeptides in the hypo-thalamus of developing rats without affecting food intake. Endocrinology 143,4683-4692.
    • (2002) Endocrinology , vol.143 , pp. 4683-4692
    • Proulx, K.1    Richard, D.2    Walker, C.-D.3
  • 92
    • 0345275807 scopus 로고    scopus 로고
    • Gestational diabetes induces placental genes for chronic stress and inflammatory pathways
    • Radaelli, T., Varastehpour, A., Cata-lano, P., and Hauguel-de Mouzon, S. (2003). Gestational diabetes induces placental genes for chronic stress and inflammatory pathways. Diabetes 52,2951-2958.
    • (2003) Diabetes , vol.52 , pp. 2951-2958
    • Radaelli, T.1    Varastehpour, A.2    Cata-lano, P.3    Hauguel-de Mouzon, S.4
  • 93
    • 78049511450 scopus 로고    scopus 로고
    • Impact of maternal periconceptional overnutrition on fat mass and expression of adi-pogenic and lipogenic genes in visceral and subcutaneous fat depots in the postnatal lamb
    • Rattanatray, L., MacLaughlin, S. M., Kleemann, D. O., Walker, S. K., Muhlhausler, B. S., and McMillen, I. C. (2010). Impact of maternal periconceptional overnutrition on fat mass and expression of adi-pogenic and lipogenic genes in visceral and subcutaneous fat depots in the postnatal lamb. Endocrinology 151,5195-5205.
    • (2010) Endocrinology , vol.151 , pp. 5195-5205
    • Rattanatray, L.1    MacLaughlin, S.M.2    Kleemann, D.O.3    Walker, S.K.4    Muhlhausler, B.S.5    McMillen, I.C.6
  • 95
    • 38549142800 scopus 로고    scopus 로고
    • Oral supplementation with physiological doses of leptin during lactation in rats improves insulin sensitivity and affects food preferences later in life
    • Sánchez, J., Priego, T., Palou, M., Tobaruela, A., Palou, A., and Picó, C. (2008). Oral supplementation with physiological doses of leptin during lactation in rats improves insulin sensitivity and affects food preferences later in life. Endocrinology 149, 733-740.
    • (2008) Endocrinology , vol.149 , pp. 733-740
    • Sánchez, J.1    Priego, T.2    Palou, M.3    Tobaruela, A.4    Palou, A.5    Picó, C.6
  • 96
    • 78650057814 scopus 로고    scopus 로고
    • Maternal antioxidant supplementation prevents adiposity in the offspring of Western diet-fed rats
    • Sen, S., and Simmons, R. A. (2010). Maternal antioxidant supplementation prevents adiposity in the offspring of Western diet-fed rats. Diabetes 59, 3058-3065.
    • (2010) Diabetes , vol.59 , pp. 3058-3065
    • Sen, S.1    Simmons, R.A.2
  • 100
    • 2442454953 scopus 로고    scopus 로고
    • Breastmilk feeding and lipoprotein profile in adolescents born preterm: follow-up of a prospective randomised study
    • Singhal, A., Cole, T. J., Fewtrell, M., and Lucas, A. (2004). Breastmilk feeding and lipoprotein profile in adolescents born preterm: follow-up of a prospective randomised study. Lancet 363, 1571-1578.
    • (2004) Lancet , vol.363 , pp. 1571-1578
    • Singhal, A.1    Cole, T.J.2    Fewtrell, M.3    Lucas, A.4
  • 103
    • 33749234763 scopus 로고    scopus 로고
    • Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood
    • Srinivasan, M., Katewa, S. D., Palaniyap-pan, A., Pandya, J. D., and Patel, M. S. (2006). Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood. Am. J. Physiol. Endocrinol. Metab. 291, E792-E799.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291
    • Srinivasan, M.1    Katewa, S.D.2    Palaniyap-pan, A.3    Pandya, J.D.4    Patel, M.S.5
  • 105
    • 17644403205 scopus 로고    scopus 로고
    • Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula
    • Stettler, N., Stallings, V. A., Troxel, A. B., Zhao, J., Schinnar, R., Nelson, S. E., Ziegler, E. E., and Strom, B. L. (2005). Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula. Circulation 111, 1897-1903.
    • (2005) Circulation , vol.111 , pp. 1897-1903
    • Stettler, N.1    Stallings, V.A.2    Troxel, A.B.3    Zhao, J.4    Schinnar, R.5    Nelson, S.E.6    Ziegler, E.E.7    Strom, B.L.8
  • 108
    • 77952309022 scopus 로고    scopus 로고
    • Relation of immediate postnatal growth with obesity and related metabolic risk factors in adulthood: the northern Finland birth cohort 1966study
    • Tzoulaki, I., Sovio, U., Pillas, D., Har-tikainen, A.-L., Pouta, A., Laitinen, Jaana, Tammelin, T. H., Jarvelin, M.-R., and Elliott, P. (2010). Relation of immediate postnatal growth with obesity and related metabolic risk factors in adulthood: the northern Finland birth cohort 1966study.Am. J. Epidemiol. 171, 989-998.
    • (2010) Am. J. Epidemiol. , vol.171 , pp. 989-998
    • Tzoulaki, I.1    Sovio, U.2    Pillas, D.3    Har-tikainen, A.-L.4    Pouta, A.5    Laitinen, J.6    Tammelin, T.H.7    Jarvelin, M.-R.8    Elliott, P.9
  • 112
    • 41549115092 scopus 로고    scopus 로고
    • The effect of neonatal leptin treatment on postnatal weight gain in male rats is dependent on maternal nutritional status during pregnancy
    • Vickers, M. H., Gluckman, P. D., Coveny, A. H., Hofman, P. L., Cutfield, W. S., Gertler, A., Breier, B. H., and Harris, M. (2008). The effect of neonatal leptin treatment on postnatal weight gain in male rats is dependent on maternal nutritional status during pregnancy. Endocrinology 149, 1906-1913.
    • (2008) Endocrinology , vol.149 , pp. 1906-1913
    • Vickers, M.H.1    Gluckman, P.D.2    Coveny, A.H.3    Hofman, P.L.4    Cutfield, W.S.5    Gertler, A.6    Breier, B.H.7    Harris, M.8
  • 113
    • 33748957030 scopus 로고    scopus 로고
    • Interpregnancy weight change and risk of adverse pregnancy outcomes: a population-based study
    • Villamor, E., and Cnattingius, S. (2006). Interpregnancy weight change and risk of adverse pregnancy outcomes: a population-based study. Lancet 368,1164-1170.
    • (2006) Lancet , vol.368 , pp. 1164-1170
    • Villamor, E.1    Cnattingius, S.2
  • 114
    • 77957258099 scopus 로고    scopus 로고
    • Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes
    • Vucetic, Z., Kimmel, J., Totoki, K., Hollenbeck, E., and Reyes, T. M. (2010). Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology 151,4756-4764.
    • (2010) Endocrinology , vol.151 , pp. 4756-4764
    • Vucetic, Z.1    Kimmel, J.2    Totoki, K.3    Hollenbeck, E.4    Reyes, T.M.5
  • 115
    • 77955293072 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes
    • Wang, C.-H., Wang, C.-C., and Wei, Y.-H. (2010). Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes. Ann. N. Y. Acad. Sci. 1201, 157-165.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1201 , pp. 157-165
    • Wang, C.-H.1    Wang, C.-C.2    Wei, Y.-H.3
  • 116
    • 0347123629 scopus 로고    scopus 로고
    • Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases
    • Waterland, R. (2004). Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition 20, 63-68.
    • (2004) Nutrition , vol.20 , pp. 63-68
    • Waterland, R.1
  • 117
    • 0036192558 scopus 로고    scopus 로고
    • Early postnatal nutrition determines adult pancreatic glucose-responsive insulin secretion and islet gene expression in rats
    • Waterland, R. A., and Garza, C. (2002). Early postnatal nutrition determines adult pancreatic glucose-responsive insulin secretion and islet gene expression in rats. J. Nutr. 132, 357-364.
    • (2002) J. Nutr. , vol.132 , pp. 357-364
    • Waterland, R.A.1    Garza, C.2
  • 118
    • 77953073432 scopus 로고    scopus 로고
    • Comparing maternal and paternal intergenerational transmission of obesity risk in a large population-based sample
    • Whitaker, K. L., Jarvis, M. J., Beeken, R. J.,Boniface,D.,and Wardle, J. (2010). Comparing maternal and paternal intergenerational transmission of obesity risk in a large population-based sample. Am. J. Clin. Nutr. 91, 1560-1567.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 1560-1567
    • Whitaker, K.L.1    Jarvis, M.J.2    Beeken, R.J.3    Boniface, D.4    Wardle, J.5
  • 120
    • 0027319108 scopus 로고
    • Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse
    • Wilding, J. P., Gilbey, S. G., Bailey, C. J., Batt, R. A., Williams, G., Ghatei, M. A., and Bloom, S. R. (1993). Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 132, 1939-1944.
    • (1993) Endocrinology , vol.132 , pp. 1939-1944
    • Wilding, J.P.1    Gilbey, S.G.2    Bailey, C.J.3    Batt, R.A.4    Williams, G.5    Ghatei, M.A.6    Bloom, S.R.7
  • 121
    • 73649134358 scopus 로고    scopus 로고
    • Up-regulationof Toll-like receptor 4/nuclear factor-kappaB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese sheep at late gestation
    • Yan, X., Zhu, M. J., Xu, W., Tong, J. E, Ford, S. P., Nathanielsz, P. W., and Du, M. (2010).Up-regulationof Toll-like receptor 4/nuclear factor-kappaB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese sheep at late gestation. Endocrinology 151,380-387.
    • (2010) Endocrinology , vol.151 , pp. 380-387
    • Yan, X.1    Zhu, M.J.2    Xu, W.3    Tong, J.E.4    Ford, S.P.5    Nathanielsz, P.W.6    Du, M.7
  • 122
    • 77954075953 scopus 로고    scopus 로고
    • Dietary intervention prior to pregnancy reverses metabolic programming in male offspring of obese rats
    • Zambrano, E., Martínez-Samayoa, P. M., Rodríguez-González, G. L., and Nathanielsz, P. W. (2010). Dietary intervention prior to pregnancy reverses metabolic programming in male offspring of obese rats. J. Physiol. 588(Pt 10), 1791-1799.
    • (2010) J. Physiol. , vol.588 , Issue.PART 10 , pp. 1791-1799
    • Zambrano, E.1    Martínez-Samayoa, P.M.2    Rodríguez-González, G.L.3    Nathanielsz, P.W.4
  • 123
    • 70449704430 scopus 로고    scopus 로고
    • Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring
    • doi: 10.1186/1471-2164-10-478
    • Zhang, J., Zhang, F., Didelot, X., Bruce, K. D., Cagampang, F. R., Vatish, M., Hanson, M., Lehnert, H., Ceriello, A., and Byrne, C. D. (2009). Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring. BMC Genomics 10, 478. doi: 10.1186/1471-2164-10-478
    • (2009) BMC Genomics , vol.10 , pp. 478
    • Zhang, J.1    Zhang, F.2    Didelot, X.3    Bruce, K.D.4    Cagampang, F.R.5    Vatish, M.6    Hanson, M.7    Lehnert, H.8    Ceriello, A.9    Byrne, C.D.10
  • 124
    • 78649451421 scopus 로고    scopus 로고
    • Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term
    • Zhang, L., Long, N. M., Hein, S. M., Ma, Y., Nathanielsz, P. W., and Ford, S. P. (2011). Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term. Domest. Anim. Endocrinol. 40, 30-39.
    • (2011) Domest. Anim. Endocrinol. , vol.40 , pp. 30-39
    • Zhang, L.1    Long, N.M.2    Hein, S.M.3    Ma, Y.4    Nathanielsz, P.W.5    Ford, S.P.6
  • 125
    • 77951974181 scopus 로고    scopus 로고
    • Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta
    • Zhu, M. J., Du, M., Nathanielsz, P. W., and Ford, S. P. (2010a). Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta. Placenta 31,387-391.
    • (2010) Placenta , vol.31 , pp. 387-391
    • Zhu, M.J.1    Du, M.2    Nathanielsz, P.W.3    Ford, S.P.4
  • 126
    • 78149485096 scopus 로고    scopus 로고
    • Maternal obesity markedly increases pla-cental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe
    • Zhu, M. J., Ma, Y., Long, N. M., Du, M., and Ford, S. P. (2010b). Maternal obesity markedly increases pla-cental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299, R1224-R1231.
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.299
    • Zhu, M.J.1    Ma, Y.2    Long, N.M.3    Du, M.4    Ford, S.P.5
  • 127
    • 43749110487 scopus 로고    scopus 로고
    • AMP-activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over-nourished sheep
    • Zhu, M. J., Han, B., Tong, J., Ma, C., Kimzey, J. M., Underwood, K. R., Xiao, Y., Hess, B. W., Ford, S. P., Nathanielsz, P. W., and Du, M. (2008). AMP-activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over-nourished sheep. J. Physiol. (Lond.) 586, 2651-2664.
    • (2008) J. Physiol. (Lond. ) , vol.586 , pp. 2651-2664
    • Zhu, M.J.1    Han, B.2    Tong, J.3    Ma, C.4    Kimzey, J.M.5    Underwood, K.R.6    Xiao, Y.7    Hess, B.W.8    Ford, S.P.9    Nathanielsz, P.W.10    Du, M.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.