-
1
-
-
84871036375
-
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
-
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2095-128.
-
(2012)
Lancet
, vol.380
, pp. 2095-2128
-
-
Lozano, R.1
Naghavi, M.2
Foreman, K.3
Lim, S.4
Shibuya, K.5
Aboyans, V.6
-
2
-
-
84860287080
-
Epidemiology of viral hepatitis and hepatocellular carcinoma
-
e1
-
El-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 2012; 142. 1264-1273.e1.
-
(2012)
Gastroenterology
, vol.142
, pp. 1264-1273
-
-
El-Serag, H.B.1
-
4
-
-
57349191046
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-90.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
-
5
-
-
80053088189
-
Hepatocellular carcinoma
-
El-Serag HB. Hepatocellular carcinoma. N Engl J Med 2011; 365: 1118-27.
-
(2011)
N Engl J Med
, vol.365
, pp. 1118-1127
-
-
El-Serag, H.B.1
-
6
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, et al. Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 2008; 359: 1995-2004.
-
(2008)
N Engl J Med
, vol.359
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
Peix, J.4
Chiang, D.Y.5
Camargo, A.6
-
7
-
-
0035128185
-
Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: A cost effectiveness analysis
-
Bolondi L, Sofia S, Siringo S, Gaiani S, Casali A, Zironi G, et al. Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: A cost effectiveness analysis. Gut 2001; 48: 251-9.
-
(2001)
Gut
, vol.48
, pp. 251-259
-
-
Bolondi, L.1
Sofia, S.2
Siringo, S.3
Gaiani, S.4
Casali, A.5
Zironi, G.6
-
8
-
-
77955472579
-
Evolving challenges in hepatic fibrosis
-
Friedman SL. Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol 2010; 7: 425-36.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 425-436
-
-
Friedman, S.L.1
-
9
-
-
51049090381
-
Hepatitis B virus genotype and mutants: Risk factors for hepatocellular carcinoma
-
Llovet JM, Lok A. Hepatitis B virus genotype and mutants: Risk factors for hepatocellular carcinoma. J Natl Cancer Inst 2008; 100: 1121-3.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1121-1123
-
-
Llovet, J.M.1
Lok, A.2
-
10
-
-
51049117284
-
Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma
-
Yang HI, Yeh SH, Chen PJ, Iloeje UH, Jen CL, Su J, et al. Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma. J Natl Cancer Inst 2008; 100: 1134-43.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1134-1143
-
-
Yang, H.I.1
Yeh, S.H.2
Chen, P.J.3
Iloeje, U.H.4
Jen, C.L.5
Su, J.6
-
11
-
-
67349105629
-
Hepatitis C virus genotype 1b as a risk factor for hepatocellular carcinoma development: A meta-analysis
-
Raimondi S, Bruno S, Mondelli MU, Maisonneuve P. Hepatitis C virus genotype 1b as a risk factor for hepatocellular carcinoma development: A meta-analysis. J Hepatol 2009; 50: 1142-54.
-
(2009)
J Hepatol
, vol.50
, pp. 1142-1154
-
-
Raimondi, S.1
Bruno, S.2
Mondelli, M.U.3
Maisonneuve, P.4
-
12
-
-
84864428936
-
Prevention of hepatocellular carcinoma: Potential targets, experimental models, and clinical challenges
-
Hoshida Y, Fuchs BC, Tanabe KK. Prevention of hepatocellular carcinoma: Potential targets, experimental models, and clinical challenges. Curr Cancer Drug Targets 2012; 12: 1129-59.
-
(2012)
Curr Cancer Drug Targets
, vol.12
, pp. 1129-1159
-
-
Hoshida, Y.1
Fuchs, B.C.2
Tanabe, K.K.3
-
13
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266: 66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
-
14
-
-
0029089259
-
Hereditary nonpolyposis colorectal cancer: The syndrome, the genes, and historical perspectives
-
Marra G, Boland CR. Hereditary nonpolyposis colorectal cancer: The syndrome, the genes, and historical perspectives. J Natl Cancer Inst 1995; 87: 1114-25.
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1114-1125
-
-
Marra, G.1
Boland, C.R.2
-
15
-
-
18544380387
-
Parameters for reliable results in genetic association studies in common disease
-
Dahlman I, Eaves IA, Kosoy R, Morrison VA, Heward J, Gough SCL, et al. Parameters for reliable results in genetic association studies in common disease. Nat Genet 2002; 30: 149-50.
-
(2002)
Nat Genet
, vol.30
, pp. 149-150
-
-
Dahlman, I.1
Eaves, I.A.2
Kosoy, R.3
Morrison, V.A.4
Heward, J.5
Gough, S.C.L.6
-
16
-
-
79959996152
-
A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma
-
Abu Dayyeh BK, Yang M, Fuchs BC, Karl DL, Yamada S, Sninsky JJ, et al. A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma. Gastroenterology 2011; 141: 141-9.
-
(2011)
Gastroenterology
, vol.141
, pp. 141-149
-
-
Abu Dayyeh, B.K.1
Yang, M.2
Fuchs, B.C.3
Karl, D.L.4
Yamada, S.5
Sninsky, J.J.6
-
17
-
-
38049059334
-
Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis
-
Tanabe KK, Lemoine A, Finkelstein DM, Kawasaki H, Fujii T, Chung RT, et al. Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis. JAMA 2008; 299: 53-60.
-
(2008)
JAMA
, vol.299
, pp. 53-60
-
-
Tanabe, K.K.1
Lemoine, A.2
Finkelstein, D.M.3
Kawasaki, H.4
Fujii, T.5
Chung, R.T.6
-
18
-
-
84881436148
-
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions
-
Nault JC, Mallet M, Pilati C, Calderaro J, Bioulac-Sage P, Laurent C, et al. High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions. Nat Commun 2013; 4: 2218.
-
(2013)
Nat Commun
, vol.4
, pp. 2218
-
-
Nault, J.C.1
Mallet, M.2
Pilati, C.3
Calderaro, J.4
Bioulac-Sage, P.5
Laurent, C.6
-
19
-
-
79955631558
-
Genetics of hepatobiliary carcinogenesis
-
Nault JC, Zucman-Rossi J. Genetics of hepatobiliary carcinogenesis. Semin Liver Dis 2011; 31: 173-87.
-
(2011)
Semin Liver Dis
, vol.31
, pp. 173-187
-
-
Nault, J.C.1
Zucman-Rossi, J.2
-
20
-
-
33747029250
-
Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
-
Budhu A, Forgues M, Ye QH, Jia HL, He P, Zanetti KA, et al. Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 2006; 10: 99-111.
-
(2006)
Cancer Cell
, vol.10
, pp. 99-111
-
-
Budhu, A.1
Forgues, M.2
Ye, Q.H.3
Jia, H.L.4
He, P.5
Zanetti, K.A.6
-
21
-
-
84876474584
-
Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis
-
Hoshida Y, Villanueva A, Sangiovanni A, Sole M, Hur C, Andersson KL, et al. Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis. Gastroenterology 2013; 144: 1024-30.
-
(2013)
Gastroenterology
, vol.144
, pp. 1024-1030
-
-
Hoshida, Y.1
Villanueva, A.2
Sangiovanni, A.3
Sole, M.4
Hur, C.5
Andersson, K.L.6
-
22
-
-
84900450842
-
Transcriptome profiling of archived sectioned formalin-fixed paraffin-embedded (AS-FFPE) tissue for disease classification
-
Kojima K, April C, Canasto-Chibuque C, Chen X, Deshmukh M, Venkatesh A, et al. Transcriptome profiling of archived sectioned formalin-fixed paraffin-embedded (AS-FFPE) tissue for disease classification. PLoS One 2014; 9: E86961.
-
(2014)
PLoS One
, vol.9
, pp. e86961
-
-
Kojima, K.1
April, C.2
Canasto-Chibuque, C.3
Chen, X.4
Deshmukh, M.5
Venkatesh, A.6
-
23
-
-
79952231921
-
Management of hepatocellular carcinoma: An update
-
Bruix J, Sherman M. Management of hepatocellular carcinoma: An update. Hepatology 2011; 53: 1020-2.
-
(2011)
Hepatology
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
24
-
-
84858658381
-
EASL-EORTC clinical practice guidelines: Management of hepatocellular carcinoma
-
EASL-EORTC clinical practice guidelines: Management of hepatocellular carcinoma. J Hepatol 2012; 56: 908-43.
-
(2012)
J Hepatol
, vol.56
, pp. 908-943
-
-
-
26
-
-
34247549347
-
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
-
Wurmbach E, Chen Y, Khitrov G, Zhang W, Roayaie S, Schwartz M, et al. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. Hepatology 2007; 45: 938-47.
-
(2007)
Hepatology
, vol.45
, pp. 938-947
-
-
Wurmbach, E.1
Chen, Y.2
Khitrov, G.3
Zhang, W.4
Roayaie, S.5
Schwartz, M.6
-
27
-
-
25844461787
-
Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling
-
Nam SW, Park JY, Ramasamy A, Shevade S, Islam A, Long PM, et al. Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 2005; 42: 809-18.
-
(2005)
Hepatology
, vol.42
, pp. 809-818
-
-
Nam, S.W.1
Park, J.Y.2
Ramasamy, A.3
Shevade, S.4
Islam, A.5
Long, P.M.6
-
28
-
-
0041343280
-
Molecular profiling of hepatocellular carcinomas (HCC) using a large-scale real-time RT-PCR approach: Determination of a molecular diagnostic index
-
Paradis V, Bieche I, Dargere D, Laurendeau I, Laurent C, Bioulac Sage P, et al. Molecular profiling of hepatocellular carcinomas (HCC) using a large-scale real-time RT-PCR approach: Determination of a molecular diagnostic index. Am J Pathol 2003; 163: 733-41.
-
(2003)
Am J Pathol
, vol.163
, pp. 733-741
-
-
Paradis, V.1
Bieche, I.2
Dargere, D.3
Laurendeau, I.4
Laurent, C.5
Bioulac Sage, P.6
-
29
-
-
33845790499
-
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis
-
Llovet JM, Chen Y, Wurmbach E, Roayaie S, Fiel MI, Schwartz M, et al. A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis. Gastroenterology 2006; 131: 1758-67.
-
(2006)
Gastroenterology
, vol.131
, pp. 1758-1767
-
-
Llovet, J.M.1
Chen, Y.2
Wurmbach, E.3
Roayaie, S.4
Fiel, M.I.5
Schwartz, M.6
-
30
-
-
9744265831
-
Initial response to percutaneous ablation predicts survival in patients with hepatocellular carcinoma
-
Sala M, Llovet JM, Vilana R, Bianchi L, Solé M, Ayuso C, et al. Initial response to percutaneous ablation predicts survival in patients with hepatocellular carcinoma. Hepatology 2004; 40: 1352-60.
-
(2004)
Hepatology
, vol.40
, pp. 1352-1360
-
-
Sala, M.1
Llovet, J.M.2
Vilana, R.3
Bianchi, L.4
Solé, M.5
Ayuso, C.6
-
31
-
-
44449085884
-
Design and endpoints of clinical trials in hepatocellular carcinoma
-
Llovet JM, Di Bisceglie AM, Bruix J, Kramer BS, Lencioni R, Zhu AX, et al. Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 2008; 100: 698-711.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 698-711
-
-
Llovet, J.M.1
Di Bisceglie, A.M.2
Bruix, J.3
Kramer, B.S.4
Lencioni, R.5
Zhu, A.X.6
-
32
-
-
28844480321
-
Management of hepatocellular carcinoma
-
Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-36.
-
(2005)
Hepatology
, vol.42
, pp. 1208-1236
-
-
Bruix, J.1
Sherman, M.2
-
33
-
-
38049123402
-
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia
-
Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, et al. MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci U S A 2007; 104: 19971-6.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19971-1976
-
-
Mi, S.1
Lu, J.2
Sun, M.3
Li, Z.4
Zhang, H.5
Neilly, M.B.6
-
35
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B, Goldhirsch A, Untch M, Smith I, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353: 1659-72.
-
(2005)
N Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
Goldhirsch, A.4
Untch, M.5
Smith, I.6
-
36
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T, Jänne PA, Kocher O, Meyerson M, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005; 352: 786-92.
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
Jänne, P.A.4
Kocher, O.5
Meyerson, M.6
-
37
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Tebbutt NC, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008; 359: 1757-65.
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
-
38
-
-
26944496117
-
REporting recommendations for tumor marker prognostic studies (REMARK)
-
McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM. REporting recommendations for tumor marker prognostic studies (REMARK) . Nat Clin Pract Urol 2005; 2: 416-22.
-
(2005)
Nat Clin Pract Urol
, vol.2
, pp. 416-422
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
Taube, S.E.4
Gion, M.5
Clark, G.M.6
-
39
-
-
84874484807
-
Prognosis research strategy (PROGRESS) 1: A framework for researching clinical outcomes
-
Hemingway H, Croft P, Perel P, Hayden JA, Abrams K, Timmis A, et al. Prognosis research strategy (PROGRESS) 1: A framework for researching clinical outcomes. BMJ 2013; 346: E5595.
-
(2013)
BMJ
, vol.346
, pp. e5595
-
-
Hemingway, H.1
Croft, P.2
Perel, P.3
Hayden, J.A.4
Abrams, K.5
Timmis, A.6
-
40
-
-
78650361904
-
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
-
Roessler S, Jia HLL, Budhu A, Forgues M, Ye QHH, Lee JSS, et al. A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients. Cancer Res 2010; 70: 10202-12.
-
(2010)
Cancer Res
, vol.70
, pp. 10202-10212
-
-
Roessler, S.1
Jia, H.L.L.2
Budhu, A.3
Forgues, M.4
Ye, Q.H.H.5
Lee, J.S.S.6
-
41
-
-
0037391756
-
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
-
Ye QH, Qin LX, Forgues M, He P, Kim JW, Peng AC, et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 2003; 9: 416-23.
-
(2003)
Nat Med
, vol.9
, pp. 416-423
-
-
Ye, Q.H.1
Qin, L.X.2
Forgues, M.3
He, P.4
Kim, J.W.5
Peng, A.C.6
-
42
-
-
0037443891
-
Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection
-
Iizuka N, Oka M, Yamada-Okabe H, Nishida M, Maeda Y, Mori N, et al. Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet 2003; 361: 923-9.
-
(2003)
Lancet
, vol.361
, pp. 923-929
-
-
Iizuka, N.1
Oka, M.2
Yamada-Okabe, H.3
Nishida, M.4
Maeda, Y.5
Mori, N.6
-
43
-
-
61349127144
-
Molecular prediction of early recurrence after resection of hepatocellular carcinoma
-
Yoshioka S, Takemasa I, Nagano H, Kittaka N, Noda T, Wada H, et al. Molecular prediction of early recurrence after resection of hepatocellular carcinoma. Eur J Cancer 2009; 45: 881-9.
-
(2009)
Eur J Cancer
, vol.45
, pp. 881-889
-
-
Yoshioka, S.1
Takemasa, I.2
Nagano, H.3
Kittaka, N.4
Noda, T.5
Wada, H.6
-
44
-
-
4444286417
-
Molecular-based prediction of early recurrence in hepatocellular carcinoma
-
Kurokawa Y, Matoba R, Takemasa I, Nagano H, Dono K, Nakamori S, et al. Molecular-based prediction of early recurrence in hepatocellular carcinoma. J Hepatol 2004; 41: 284-91.
-
(2004)
J Hepatol
, vol.41
, pp. 284-291
-
-
Kurokawa, Y.1
Matoba, R.2
Takemasa, I.3
Nagano, H.4
Dono, K.5
Nakamori, S.6
-
45
-
-
33745225917
-
Specific gene-expression profiles of noncancerous liver tissue predict the risk for multicentric occurrence of hepatocellular carcinoma in hepatitis C viruspositive patients
-
Okamoto M, Utsunomiya T, Wakiyama S, Hashimoto M, Fukuzawa K, Ezaki T, et al. Specific gene-expression profiles of noncancerous liver tissue predict the risk for multicentric occurrence of hepatocellular carcinoma in hepatitis C viruspositive patients. Ann Surg Oncol 2006; 13: 947-54.
-
(2006)
Ann Surg Oncol
, vol.13
, pp. 947-954
-
-
Okamoto, M.1
Utsunomiya, T.2
Wakiyama, S.3
Hashimoto, M.4
Fukuzawa, K.5
Ezaki, T.6
-
46
-
-
80054717602
-
Gene-expression signature of vascular invasion in hepatocellular carcinoma
-
Mínguez B, Hoshida Y, Villanueva A, Toffanin S, Cabellos L, Thung S, et al. Gene-expression signature of vascular invasion in hepatocellular carcinoma. J Hepatol 2011; 55: 1325-31.
-
(2011)
J Hepatol
, vol.55
, pp. 1325-1331
-
-
Mínguez, B.1
Hoshida, Y.2
Villanueva, A.3
Toffanin, S.4
Cabellos, L.5
Thung, S.6
-
47
-
-
77955735744
-
A seven-gene set associated with chronic hypoxia of prognostic importance in hepatocellular carcinoma
-
Van Malenstein H, Gevaert O, Libbrecht L, Daemen A, Allemeersch J, Nevens F, et al. A seven-gene set associated with chronic hypoxia of prognostic importance in hepatocellular carcinoma. Clin Cancer Res 2010; 16: 4278-88.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4278-488
-
-
Van Malenstein, H.1
Gevaert, O.2
Libbrecht, L.3
Daemen, A.4
Allemeersch, J.5
Nevens, F.6
-
48
-
-
53049086329
-
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma
-
Chiang DY, Villanueva A, Hoshida Y, Peix J, Newell P, Minguez B, et al. Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res 2008; 68: 6779-88.
-
(2008)
Cancer Res
, vol.68
, pp. 6779-6788
-
-
Chiang, D.Y.1
Villanueva, A.2
Hoshida, Y.3
Peix, J.4
Newell, P.5
Minguez, B.6
-
49
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
Boyault S, Rickman DS, de Reyniés A, Balabaud C, Rebouissou S, Jeannot E, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 2007; 45: 42-52.
-
(2007)
Hepatology
, vol.45
, pp. 42-52
-
-
Boyault, S.1
Rickman, D.S.2
De Reyniés, A.3
Balabaud, C.4
Rebouissou, S.5
Jeannot, E.6
-
50
-
-
4544273428
-
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
-
Lee JSS, Chu ISS, Heo J, Calvisi DF, Sun Z, Roskams T, et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 2004; 40: 667-76.
-
(2004)
Hepatology
, vol.40
, pp. 667-676
-
-
Lee, J.S.S.1
Chu, I.S.S.2
Heo, J.3
Calvisi, D.F.4
Sun, Z.5
Roskams, T.6
-
51
-
-
70349739285
-
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
-
Hoshida Y, Nijman SMB, Kobayashi M, Chan JA, Brunet J-PP, Chiang DY, et al. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res 2009; 69: 7385-92.
-
(2009)
Cancer Res
, vol.69
, pp. 7385-7392
-
-
Hoshida, Y.1
Nijman, S.M.B.2
Kobayashi, M.3
Chan, J.A.4
Brunet, J.-P.P.5
Chiang, D.Y.6
-
52
-
-
46249085489
-
Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer
-
Coulouarn C, Factor VM, Thorgeirsson SS. Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer. Hepatology 2008; 47: 2059-67.
-
(2008)
Hepatology
, vol.47
, pp. 2059-2067
-
-
Coulouarn, C.1
Factor, V.M.2
Thorgeirsson, S.S.3
-
53
-
-
33745220780
-
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
-
Kaposi-Novak P, Lee J-SS, Gomez-Quiroz L, Coulouarn C, Factor VM, Thorgeirsson SS, et al. Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J Clin Invest 2006; 116: 1582-95.
-
(2006)
J Clin Invest
, vol.116
, pp. 1582-1595
-
-
Kaposi-Novak, P.1
Lee, J.-S.S.2
Gomez-Quiroz, L.3
Coulouarn, C.4
Factor, V.M.5
Thorgeirsson, S.S.6
-
54
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006; 12: 410-6.
-
(2006)
Nat Med
, vol.12
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
Chu, I.S.4
Kaposi-Novak, P.5
Calvisi, D.F.6
-
55
-
-
40449099255
-
EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
-
Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H, et al. EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res 2008; 68: 1451-61.
-
(2008)
Cancer Res
, vol.68
, pp. 1451-1461
-
-
Yamashita, T.1
Forgues, M.2
Wang, W.3
Kim, J.W.4
Ye, Q.5
Jia, H.6
-
56
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
Villanueva A, Hoshida Y, Battiston C, Tovar V, Sia D, Alsinet C, et al. Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology 2011; 140. 1501-1512 e2.
-
(2011)
Gastroenterology
, vol.140
, pp. 1501-1512e2
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
Tovar, V.4
Sia, D.5
Alsinet, C.6
-
57
-
-
77950616980
-
Progenitor-derived hepatocellular carcinoma model in the rat
-
Andersen JB, Loi R, Perra A, Factor VM, Ledda-Columbano GM, Columbano A, et al. Progenitor-derived hepatocellular carcinoma model in the rat. Hepatology 2010; 51: 1401-9.
-
(2010)
Hepatology
, vol.51
, pp. 1401-1409
-
-
Andersen, J.B.1
Loi, R.2
Perra, A.3
Factor, V.M.4
Ledda-Columbano, G.M.5
Columbano, A.6
-
58
-
-
77951037177
-
Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma
-
Woo HG, Lee JH, Yoon JH, Kim CY, Lee HS, Jang JJ, et al. Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma. Cancer Res 2010; 70: 3034-41.
-
(2010)
Cancer Res
, vol.70
, pp. 3034-3041
-
-
Woo, H.G.1
Lee, J.H.2
Yoon, J.H.3
Kim, C.Y.4
Lee, H.S.5
Jang, J.J.6
-
59
-
-
84879465430
-
A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection
-
Nault JC, De Reyniés A, Villanueva A, Calderaro J, Rebouissou S, Couchy G, et al. A hepatocellular carcinoma 5-gene score associated with survival of patients after liver resection. Gastroenterology 2013; 145: 176-87.
-
(2013)
Gastroenterology
, vol.145
, pp. 176-187
-
-
Nault, J.C.1
De Reyniés, A.2
Villanueva, A.3
Calderaro, J.4
Rebouissou, S.5
Couchy, G.6
-
60
-
-
38949184246
-
Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival
-
Jiang J, Gusev Y, Aderca I, Mettler TA, Nagorney DM, Brackett DJ, et al. Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. Clin Cancer Res 2008; 14: 419-27.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 419-427
-
-
Jiang, J.1
Gusev, Y.2
Aderca, I.3
Mettler, T.A.4
Nagorney, D.M.5
Brackett, D.J.6
-
61
-
-
40949087185
-
Identification of metastasis-related microRNAs in hepatocellular carcinoma
-
Budhu A, Jia HLL, Forgues M, Liu CGG, Goldstein D, Lam A, et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 2008; 47: 897-907.
-
(2008)
Hepatology
, vol.47
, pp. 897-907
-
-
Budhu, A.1
Jia, H.L.L.2
Forgues, M.3
Liu, C.G.G.4
Goldstein, D.5
Lam, A.6
-
62
-
-
77349092851
-
Molecular classification and novel targets in hepatocellular carcinoma: Recent advancements
-
Hoshida Y, Toffanin S, Lachenmayer A, Villanueva A, Minguez B, Llovet JM. Molecular classification and novel targets in hepatocellular carcinoma: Recent advancements. Semin Liver Dis 2010; 30: 35-51.
-
(2010)
Semin Liver Dis
, vol.30
, pp. 35-51
-
-
Hoshida, Y.1
Toffanin, S.2
Lachenmayer, A.3
Villanueva, A.4
Minguez, B.5
Llovet, J.M.6
-
63
-
-
57349087153
-
Pivotal role of mTOR signaling in hepatocellular carcinoma
-
1983 e1-11
-
Villanueva A, Chiang DY, Newell P, Peix J, Thung S, Alsinet C, et al. Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology 2008; 135: 1972-83. 1983 e1-11.
-
(2008)
Gastroenterology
, vol.135
, pp. 1972-1983
-
-
Villanueva, A.1
Chiang, D.Y.2
Newell, P.3
Peix, J.4
Thung, S.5
Alsinet, C.6
-
64
-
-
84873296666
-
MicroRNAs: New tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma?
-
Giordano S, Columbano A. MicroRNAs: New tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma? Hepatology 2013; 57: 840-7.
-
(2013)
Hepatology
, vol.57
, pp. 840-847
-
-
Giordano, S.1
Columbano, A.2
-
65
-
-
77957552077
-
New strategies in hepatocellular carcinoma: Genomic prognostic markers
-
Villanueva A, Hoshida Y, Toffanin S, Lachenmayer A, Alsinet C, Savic R, et al. New strategies in hepatocellular carcinoma: Genomic prognostic markers. Clin Cancer Res 2010; 16: 4688-94.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4688-4694
-
-
Villanueva, A.1
Hoshida, Y.2
Toffanin, S.3
Lachenmayer, A.4
Alsinet, C.5
Savic, R.6
-
66
-
-
67649881121
-
Lin28 promotes transformation and is associated with advanced human malignancies
-
Viswanathan SR, Powers JT, EinhornW, Hoshida Y, Ng TL, Toffanin S, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet 2009; 41: 843-8.
-
(2009)
Nat Genet
, vol.41
, pp. 843-848
-
-
Viswanathan, S.R.1
Powers, J.T.2
EinhornW Hoshida, Y.3
Ng, T.L.4
Toffanin, S.5
-
67
-
-
70349976819
-
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
-
Coulouarn C, Factor VM, Andersen JB, Durkin ME, Thorgeirsson SS. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene 2009; 28: 3526-36.
-
(2009)
Oncogene
, vol.28
, pp. 3526-3536
-
-
Coulouarn, C.1
Factor, V.M.2
Andersen, J.B.3
Durkin, M.E.4
Thorgeirsson, S.S.5
-
68
-
-
70349871321
-
MicroRNA expression, survival, and response to interferon in liver cancer
-
Ji J, Shi J, Budhu A, Yu Z, Forgues M, Roessler S, et al. MicroRNA expression, survival, and response to interferon in liver cancer. N Engl J Med 2009; 361: 1437-47.
-
(2009)
N Engl J Med
, vol.361
, pp. 1437-1447
-
-
Ji, J.1
Shi, J.2
Budhu, A.3
Yu, Z.4
Forgues, M.5
Roessler, S.6
-
69
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009; 137: 1005-17.
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
-
70
-
-
77449158438
-
MiRNA delivery: Emerging therapy for hepatocellular carcinoma
-
Toffanin S, Villanueva A, Llovet JM. miRNA delivery: Emerging therapy for hepatocellular carcinoma. Gastroenterology 2010; 138: 1202-4.
-
(2010)
Gastroenterology
, vol.138
, pp. 1202-1204
-
-
Toffanin, S.1
Villanueva, A.2
Llovet, J.M.3
-
71
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364: 2507-16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
-
72
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-smallcell lung cancer
-
Kwak EL, Bang YJJ, Camidge DR, Shaw AT, Solomon B, Maki RG, et al. Anaplastic lymphoma kinase inhibition in non-smallcell lung cancer. N Engl J Med 2010; 363: 1693-703.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
Maki, R.G.6
-
73
-
-
84898989382
-
Hepatocellular carcinoma: Reasons for phase III failure and novel perspectives on trial design
-
Llovet JM, Hernandez-Gea V. Hepatocellular carcinoma: Reasons for phase III failure and novel perspectives on trial design. Clin Cancer Res 2014; 20: 2072-9.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2072-2079
-
-
Llovet, J.M.1
Hernandez-Gea, V.2
-
74
-
-
84895901513
-
Liver cancer in 2013: Mutational landscape of HCC - The end of the beginning
-
Villanueva A, Llovet JM. Liver cancer in 2013: Mutational landscape of HCC - The end of the beginning. Nat Rev Clin Oncol 2014; 11: 73-4.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 73-74
-
-
Villanueva, A.1
Llovet, J.M.2
-
75
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10: 789-99.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
76
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad I Ben, et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 2012; 44: 694-8.
-
(2012)
Nat Genet
, vol.44
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
Ladeiro, Y.4
Pelletier, L.5
Maad I Ben.6
-
77
-
-
84862976633
-
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
-
Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet 2012; 44: 760-4.
-
(2012)
Nat Genet
, vol.44
, pp. 760-764
-
-
Fujimoto, A.1
Totoki, Y.2
Abe, T.3
Boroevich, K.A.4
Hosoda, F.5
Nguyen, H.H.6
-
78
-
-
33745532794
-
Genetics of hepatocellular tumors
-
Laurent-Puig P, Zucman-Rossi J. Genetics of hepatocellular tumors. Oncogene 2006; 25: 3778-86.
-
(2006)
Oncogene
, vol.25
, pp. 3778-3786
-
-
Laurent-Puig, P.1
Zucman-Rossi, J.2
-
79
-
-
84876976986
-
Novel anticancer therapeutics targeting telomerase
-
Ruden M, Puri N. Novel anticancer therapeutics targeting telomerase. Cancer Treat Rev 2013; 39: 444-56.
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 444-456
-
-
Ruden, M.1
Puri, N.2
-
80
-
-
84871721240
-
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: A randomised, placebo-controlled phase 2 study
-
Santoro A, Rimassa L, Borbath I, Daniele B, Salvagni S, Van Laethem JL, et al. Tivantinib for second-line treatment of advanced hepatocellular carcinoma: A randomised, placebo-controlled phase 2 study. Lancet Oncol 2013; 14: 55-63.
-
(2013)
Lancet Oncol
, vol.14
, pp. 55-63
-
-
Santoro, A.1
Rimassa, L.2
Borbath, I.3
Daniele, B.4
Salvagni, S.5
Van Laethem, J.L.6
-
81
-
-
84901747256
-
Cabozantinib suppresses tumor growth and metastasis in hepatocellular carcinoma by a dual blockade of VEGFR2 and MET
-
Xiang Q, Chen W, Ren M, Wang J, Zhang H, Deng DYB, et al. Cabozantinib suppresses tumor growth and metastasis in hepatocellular carcinoma by a dual blockade of VEGFR2 and MET. Clin Cancer Res 2014; 20: 2959-70.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2959-2970
-
-
Xiang, Q.1
Chen, W.2
Ren, M.3
Wang, J.4
Zhang, H.5
Deng, D.Y.B.6
-
82
-
-
77949875878
-
IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage
-
Tovar V, Alsinet C, Villanueva A, Hoshida Y, Chiang DY, Solé M, et al. IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage. J Hepatol 2010; 52: 550-9.
-
(2010)
J Hepatol
, vol.52
, pp. 550-559
-
-
Tovar, V.1
Alsinet, C.2
Villanueva, A.3
Hoshida, Y.4
Chiang, D.Y.5
Solé, M.6
-
83
-
-
84887093344
-
Allosteric MEK1/2 inhibitor refametinib (BAY 86-9766) in combination with sorafenib exhibits antitumor activity in preclinical murine and rat models of hepatocellular carcinoma
-
Schmieder R, Puehler F, Neuhaus R, Kissel M, Adjei AA, Miner JN, et al. Allosteric MEK1/2 inhibitor refametinib (BAY 86-9766) in combination with sorafenib exhibits antitumor activity in preclinical murine and rat models of hepatocellular carcinoma. Neoplasia 2013; 15: 1161-71.
-
(2013)
Neoplasia
, vol.15
, pp. 1161-1171
-
-
Schmieder, R.1
Puehler, F.2
Neuhaus, R.3
Kissel, M.4
Adjei, A.A.5
Miner, J.N.6
-
84
-
-
84900320514
-
Focal gains of VEGFA: Candidate predictors of sorafenib response in hepatocellular carcinoma
-
Llovet JM. Focal gains of VEGFA: Candidate predictors of sorafenib response in hepatocellular carcinoma. Cancer Cell 2014; 25: 560-2.
-
(2014)
Cancer Cell
, vol.25
, pp. 560-562
-
-
Llovet, J.M.1
-
85
-
-
79952497178
-
Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by oncogenomic screening
-
Sawey ET, Chanrion M, Cai C, Wu G, Zhang J, Zender L, et al. Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by oncogenomic screening. Cancer Cell 2011; 19: 347-58.
-
(2011)
Cancer Cell
, vol.19
, pp. 347-358
-
-
Sawey, E.T.1
Chanrion, M.2
Cai, C.3
Wu, G.4
Zhang, J.5
Zender, L.6
-
86
-
-
84904054856
-
Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment
-
Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, et al. Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment. Cancer Discov 2014; 4: 730-43.
-
(2014)
Cancer Discov
, vol.4
, pp. 730-743
-
-
Horwitz, E.1
Stein, I.2
Andreozzi, M.3
Nemeth, J.4
Shoham, A.5
Pappo, O.6
-
87
-
-
84898023508
-
Decoding complex patterns of genomic rearrangement in hepatocellular carcinoma
-
Fernandez-Banet J, Lee NP, Chan KT, Gao H, Liu X, Sung WK, et al. Decoding complex patterns of genomic rearrangement in hepatocellular carcinoma. Genomics 2014; 103: 189-203.
-
(2014)
Genomics
, vol.103
, pp. 189-203
-
-
Fernandez-Banet, J.1
Lee, N.P.2
Chan, K.T.3
Gao, H.4
Liu, X.5
Sung, W.K.6
-
88
-
-
84861183742
-
Combination therapy for hepatocellular carcinoma: Additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib
-
Lachenmayer A, Toffanin S, Cabellos L, Alsinet C, Hoshida Y, Villanueva A, et al. Combination therapy for hepatocellular carcinoma: Additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib. J Hepatol 2012; 56: 1343-50.
-
(2012)
J Hepatol
, vol.56
, pp. 1343-1350
-
-
Lachenmayer, A.1
Toffanin, S.2
Cabellos, L.3
Alsinet, C.4
Hoshida, Y.5
Villanueva, A.6
-
89
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010; 467: 1114-7.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
-
90
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell PJ, Yachida S, Mudie LJ, Stephens PJ, Pleasance ED, Stebbings LA, et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 2010; 467: 1109-13.
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
Yachida, S.2
Mudie, L.J.3
Stephens, P.J.4
Pleasance, E.D.5
Stebbings, L.A.6
-
91
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366: 883-92.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
92
-
-
0037371545
-
Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis
-
Ng IO, Guan X, Poon RT, Fan ST, Lee JMF. Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis. J Pathol 2003; 199: 345-53.
-
(2003)
J Pathol
, vol.199
, pp. 345-353
-
-
Ng, I.O.1
Guan, X.2
Poon, R.T.3
Fan, S.T.4
Lee, J.M.F.5
-
93
-
-
84983720414
-
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data
-
Tao Y, Ruan J, Yeh SH, Lu X, Wang Y, Zhai W, et al. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A 2011; 108: 12042-7.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12042-12047
-
-
Tao, Y.1
Ruan, J.2
Yeh, S.H.3
Lu, X.4
Wang, Y.5
Zhai, W.6
-
95
-
-
0037025173
-
Cancer. Addiction to oncogenes - The achilles heal of cancer
-
Weinstein IB. Cancer. Addiction to oncogenes - The achilles heal of cancer. Science 2002; 297: 63-4.
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
|