Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  Ahsan, Sama ^a,b   Raabe, Eric H ^a,b   Haffner, Michael C ^b   Vaghasia, Ajay ^b   Warren, Katherine E ^c   Quezado, Martha ^c   Ballester, Leomar Y ^c   Nazarian, Javad ^d,e   Eberhart, Charles G ^a,b   Rodriguez, Fausto J ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^e GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

5 hydroxymethylcytosine; 5 methylcytosine; DIPG; H3F3A; H3K27 trimethylation; H3K9 trimethylation

Indexed keywords

5 METHYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE;

AGE; ANALOGS AND DERIVATIVES; BRAIN STEM TUMOR; CHILD; DNA METHYLATION; EPIGENETICS; FEMALE; GENE EXPRESSION REGULATION; GLIOMA; HUMAN; MALE; METABOLISM; NONPARAMETRIC TEST; PHYSIOLOGY; PRESCHOOL CHILD; TISSUE MICROARRAY;

5-METHYLCYTOSINE; AGE FACTORS; BRAIN STEM NEOPLASMS; CHILD; CHILD, PRESCHOOL; CYTOSINE; DNA METHYLATION; EPIGENOMICS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MALE; STATISTICS, NONPARAMETRIC; TISSUE ARRAY ANALYSIS;

EID: 84921676910     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/2051-5960-2-59     Document Type: Article

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