-
1
-
-
84868023931
-
CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2005-2009
-
10.1093/neuonc/nos218 23095881 10.1093/neuonc/nos218
-
Dolecek TA, Propp JM, Stroup NE, Kruchko C (2012) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. Neuro Oncol 14:v1-v49. doi: 10.1093/neuonc/nos218
-
(2012)
Neuro Oncol
, vol.14
-
-
Dolecek, T.A.1
Propp, J.M.2
Stroup, N.E.3
Kruchko, C.4
-
2
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
10.1007/s00401-007-0243-4 17618441 10.1007/s00401-007-0243-4
-
Louis D, Ohgaki H, Wiestler O, Cavenee W, Burger P, Jouvet A, Scheithauer B, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97-109. doi: 10.1007/s00401-007-0243-4
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.1
Ohgaki, H.2
Wiestler, O.3
Cavenee, W.4
Burger, P.5
Jouvet, A.6
Scheithauer, B.7
Kleihues, P.8
-
3
-
-
4944255253
-
Genetic pathways to glioblastoma: A population-based study
-
10.1158/0008-5472.can-04-1337 15466178 10.1158/0008-5472.CAN-04-1337 1:CAS:528:DC%2BD2cXotFalsrc%3D
-
Ohgaki H, Dessen P, Jourde B, Horstmann S, Nishikawa T, Di Patre P-L, Burkhard C, Schüler D, Probst-Hensch NM, Maiorka PC, Baeza N, Pisani P, Yonekawa Y, Yasargil MG, Lütolf UM, Kleihues P (2004) Genetic pathways to glioblastoma: a population-based study. Cancer Res 64:6892-6899. doi: 10.1158/0008-5472.can-04-1337
-
(2004)
Cancer Res
, vol.64
, pp. 6892-6899
-
-
Ohgaki, H.1
Dessen, P.2
Jourde, B.3
Horstmann, S.4
Nishikawa, T.5
Di Patre, P.-L.6
Burkhard, C.7
Schüler, D.8
Probst-Hensch, N.M.9
Maiorka, P.C.10
Baeza, N.11
Pisani, P.12
Yonekawa, Y.13
Yasargil, M.G.14
Lütolf, U.M.15
Kleihues, P.16
-
4
-
-
71549122009
-
Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors
-
10.1111/j.1750-3639.2009.00352.x 19903171 10.1111/j.1750-3639.2009.00352. x 1:CAS:528:DC%2BC3cXpvFOlsA%3D%3D
-
Capper D, Weissert S, Balss J, Habel A, Meyer J, Jäger D, Ackermann U, Tessmer C, Korshunov A, Zentgraf H, Hartmann C, Von Deimling A (2010) Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol 20:245-254. doi: 10.1111/j.1750-3639.2009.00352.x
-
(2010)
Brain Pathol
, vol.20
, pp. 245-254
-
-
Capper, D.1
Weissert, S.2
Balss, J.3
Habel, A.4
Meyer, J.5
Jäger, D.6
Ackermann, U.7
Tessmer, C.8
Korshunov, A.9
Zentgraf, H.10
Hartmann, C.11
Von Deimling, A.12
-
5
-
-
70449518400
-
Monoclonal antibody specific for IDH-R132H mutation
-
10.1007/s00401-009-0595-z 19798509 10.1007/s00401-009-0595-z 1:CAS:528:DC%2BD1MXhtlKitLrK
-
Capper D, Zentgraf H, Balss J, Hartmann C, von Deimling A (2009) Monoclonal antibody specific for IDH-R132H mutation. Acta Neuropathol 118:599-601. doi: 10.1007/s00401-009-0595-z
-
(2009)
Acta Neuropathol
, vol.118
, pp. 599-601
-
-
Capper, D.1
Zentgraf, H.2
Balss, J.3
Hartmann, C.4
Von Deimling, A.5
-
6
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
10.1056/NEJMoa0808710 19228619 10.1056/NEJMoa0808710 1:CAS:528: DC%2BD1MXitFWru7o%3D
-
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, Velculescu VE, Vogelstein B, Bigner DD (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360:765-773. doi: 10.1056/NEJMoa0808710
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
Kos, I.7
Batinic-Haberle, I.8
Jones, S.9
Riggins, G.J.10
Friedman, H.11
Friedman, A.12
Reardon, D.13
Herndon, J.14
Kinzler, K.W.15
Velculescu, V.E.16
Vogelstein, B.17
Bigner, D.D.18
-
7
-
-
84867562009
-
IDH1 and IDH2 mutations in tumorigenesis: Mechanistic insights and clinical perspectives
-
10.1158/1078-0432.ccr-12-1773 23071358 10.1158/1078-0432.CCR-12-1773 1:CAS:528:DC%2BC38XhsFahu73E
-
Yang H, Ye D, Guan KL, Xiong Y (2012) IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives. Clin Cancer Res 18:5562-5571. doi: 10.1158/1078-0432.ccr-12-1773
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5562-5571
-
-
Yang, H.1
Ye, D.2
Guan, K.L.3
Xiong, Y.4
-
8
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
10.1056/NEJMoa043331 15758010 10.1056/NEJMoa043331 1:CAS:528: DC%2BD2MXit1Wktro%3D
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JEC, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352:997-1003. doi: 10.1056/NEJMoa043331
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
De Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.C.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
9
-
-
4143084896
-
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas
-
10.1158/1078-0432.ccr-04-0392 15297393 10.1158/1078-0432.CCR-04-0392 1:CAS:528:DC%2BD2cXmtlSisbc%3D
-
Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, Aguirre-Cruz L, García-Lopez JL, Piquer J, Safont M-J, Balaña C, Sanchez-Cespedes M, García-Villanueva M, Arribas L, Esteller M (2004) CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. Clin Cancer Res 10:4933-4938. doi: 10.1158/1078-0432.ccr-04-0392
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4933-4938
-
-
Paz, M.F.1
Yaya-Tur, R.2
Rojas-Marcos, I.3
Reynes, G.4
Pollan, M.5
Aguirre-Cruz, L.6
García-Lopez, J.L.7
Piquer, J.8
Safont, M.-J.9
Balaña, C.10
Sanchez-Cespedes, M.11
García-Villanueva, M.12
Arribas, L.13
Esteller, M.14
-
10
-
-
0032494479
-
Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas
-
10.1093/jnci/90.19.1473 9776413 10.1093/jnci/90.19.1473 1:STN:280:DyaK1cvkslejug%3D%3D
-
Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR, Silver JS, Stark PC, Macdonald DR, Ino Y, Ramsay DA, Louis DN (1998) Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 90:1473-1479. doi: 10.1093/jnci/90.19.1473
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1473-1479
-
-
Cairncross, J.G.1
Ueki, K.2
Zlatescu, M.C.3
Lisle, D.K.4
Finkelstein, D.M.5
Hammond, R.R.6
Silver, J.S.7
Stark, P.C.8
Macdonald, D.R.9
Ino, Y.10
Ramsay, D.A.11
Louis, D.N.12
-
11
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
10.1007/s00401-010-0781-z 21088844 10.1007/s00401-010-0781-z
-
Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A (2010) Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 120:707-718. doi: 10.1007/s00401-010-0781-z
-
(2010)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
Capper, D.4
Felsberg, J.5
Simon, M.6
Westphal, M.7
Schackert, G.8
Meyermann, R.9
Pietsch, T.10
Reifenberger, G.11
Weller, M.12
Loeffler, M.13
Von Deimling, A.14
-
12
-
-
84867540151
-
C-Myc and cancer metabolism
-
10.1158/1078-0432.ccr-12-0977 23071356 10.1158/1078-0432.CCR-12-0977 1:CAS:528:DC%2BC38XhsFahu73K
-
Miller DM, Thomas SD, Islam A, Muench D, Sedoris K (2012) c-Myc and cancer metabolism. Clin Cancer Res 18:5546-5553. doi: 10.1158/1078-0432.ccr-12- 0977
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5546-5553
-
-
Miller, D.M.1
Thomas, S.D.2
Islam, A.3
Muench, D.4
Sedoris, K.5
-
13
-
-
56849131763
-
C-Myc is required for maintenance of glioma cancer stem cells
-
10.1371/journal.pone.0003769 19020659 10.1371/journal.pone.0003769
-
Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN (2008) c-Myc is required for maintenance of glioma cancer stem cells. PLoS One 3:e3769. doi: 10.1371/journal.pone.0003769
-
(2008)
PLoS One
, vol.3
, pp. 3769
-
-
Wang, J.1
Wang, H.2
Li, Z.3
Wu, Q.4
Lathia, J.D.5
McLendon, R.E.6
Hjelmeland, A.B.7
Rich, J.N.8
-
14
-
-
68549115631
-
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma
-
10.1101/sqb.2008.73.047 19150964 10.1101/sqb.2008.73.047 1:CAS:528:DC%2BD1MXos1erur0%3D
-
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA (2008) Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harb Symp Quant Biol 73:427-437. doi: 10.1101/sqb.2008.73.047
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 427-437
-
-
Zheng, H.1
Ying, H.2
Yan, H.3
Kimmelman, A.C.4
Hiller, D.J.5
Chen, A.J.6
Perry, S.R.7
Tonon, G.8
Chu, G.C.9
Ding, Z.10
Stommel, J.M.11
Dunn, K.L.12
Wiedemeyer, R.13
You, M.J.14
Brennan, C.15
Wang, Y.A.16
Ligon, K.L.17
Wong, W.H.18
Chin, L.19
Depinho, R.A.20
more..
-
15
-
-
70350728803
-
MYC-induced cancer cell energy metabolism and therapeutic opportunities
-
10.1158/1078-0432.CCR-09-0889 19861459 10.1158/1078-0432.CCR-09-0889 1:CAS:528:DC%2BD1MXhtlCjsrnM
-
Dang CV, Le A, Gao P (2009) MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res 15:6479-6483. doi: 10.1158/1078-0432.CCR-09-0889
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6479-6483
-
-
Dang, C.V.1
Le, A.2
Gao, P.3
-
16
-
-
84865313576
-
Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
-
22360810 10.1111/j.1755-148X.2012.00989.x 1:CAS:528:DC%2BC38XpsFOmsbY%3D
-
Filipp F, Scott D, Ronai ZA, Osterman A, Smith J (2012) Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells. Pigment Cell Melanoma Res 25:375-383
-
(2012)
Pigment Cell Melanoma Res
, vol.25
, pp. 375-383
-
-
Filipp, F.1
Scott, D.2
Ronai, Z.A.3
Osterman, A.4
Smith, J.5
-
17
-
-
84856014884
-
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
-
1:CAS:528:DC%2BC3MXhsV2gt7fP
-
Metallo C, Gameiro P, Bell E, Mattaini K, Yang J, Hiller K, Jewell C, Johnson Z, Irvine D, Guarente L, Kelleher J, Vander Heiden M, Iliopoulos O, Stephanopoulos G (2012) Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature 481:380-384
-
(2012)
Nature
, vol.481
, pp. 380-384
-
-
Metallo, C.1
Gameiro, P.2
Bell, E.3
Mattaini, K.4
Yang, J.5
Hiller, K.6
Jewell, C.7
Johnson, Z.8
Irvine, D.9
Guarente, L.10
Kelleher, J.11
Vander Heiden, M.12
Iliopoulos, O.13
Stephanopoulos, G.14
-
18
-
-
83755178091
-
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
-
22106302 10.1073/pnas.1117773108 1:CAS:528:DC%2BC3MXhs1GjsbvP
-
Wise D, Ward P, Shay JES, Cross J, Gruber J, Sachdeva U, Platt J, DeMatteo R, Simon MC, Thompson C (2011) Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci USA 108:19611-19616
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19611-19616
-
-
Wise, D.1
Ward, P.2
Shay, J.E.S.3
Cross, J.4
Gruber, J.5
Sachdeva, U.6
Platt, J.7
Dematteo, R.8
Simon, M.C.9
Thompson, C.10
-
19
-
-
70350217425
-
Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling
-
10.1158/0008-5472.can-09-2266 19826036 10.1158/0008-5472.CAN-09-2266 1:CAS:528:DC%2BD1MXht1ynurbK
-
Yang C, Sudderth J, Dang T, Bachoo RG, McDonald JG, DeBerardinis RJ (2009) Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res 69:7986-7993. doi: 10.1158/0008-5472.can-09-2266
-
(2009)
Cancer Res
, vol.69
, pp. 7986-7993
-
-
Yang, C.1
Sudderth, J.2
Dang, T.3
Bachoo, R.G.4
McDonald, J.G.5
Deberardinis, R.J.6
-
20
-
-
84866932650
-
A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation
-
10.1038/ng.2388 22922872 10.1038/ng.2388 1:CAS:528:DC%2BC38Xht1GhtrfL
-
Jenkins RB, Xiao Y, Sicotte H, Decker PA, Kollmeyer TM, Hansen HM, Kosel ML, Zheng S, Walsh KM, Rice T, Bracci P, McCoy LS, Smirnov I, Patoka JS, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, Chang SM, Berger MS, Caron AA, Fink SR, Halder C, Rynearson AL, Fridley BL, Buckner JC, O'Neill BP, Giannini C, Lachance DH, Wiencke JK, Eckel-Passow JE, Wrensch MR (2012) A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet 44:1122-1125. doi: 10.1038/ng.2388
-
(2012)
Nat Genet
, vol.44
, pp. 1122-1125
-
-
Jenkins, R.B.1
Xiao, Y.2
Sicotte, H.3
Decker, P.A.4
Kollmeyer, T.M.5
Hansen, H.M.6
Kosel, M.L.7
Zheng, S.8
Walsh, K.M.9
Rice, T.10
Bracci, P.11
McCoy, L.S.12
Smirnov, I.13
Patoka, J.S.14
Hsuang, G.15
Wiemels, J.L.16
Tihan, T.17
Pico, A.R.18
Prados, M.D.19
Chang, S.M.20
Berger, M.S.21
Caron, A.A.22
Fink, S.R.23
Halder, C.24
Rynearson, A.L.25
Fridley, B.L.26
Buckner, J.C.27
O'Neill, B.P.28
Giannini, C.29
Lachance, D.H.30
Wiencke, J.K.31
Eckel-Passow, J.E.32
Wrensch, M.R.33
more..
-
21
-
-
0031822837
-
Tissue microarrays for high-throughput molecular profiling of tumor specimens
-
9662379 10.1038/nm0798-844 1:CAS:528:DyaK1cXktlKntr8%3D
-
Kononen J, Bubendorf L, Kallionimeni A, Barlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallionimeni O-P (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4:844-847
-
(1998)
Nat Med
, vol.4
, pp. 844-847
-
-
Kononen, J.1
Bubendorf, L.2
Kallionimeni, A.3
Barlund, M.4
Schraml, P.5
Leighton, S.6
Torhorst, J.7
Mihatsch, M.J.8
Sauter, G.9
Kallionimeni, O.-P.10
-
22
-
-
50249133616
-
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
-
18567993 10.1038/modpathol.2008.111 1:CAS:528:DC%2BD1cXhtVagsb7M
-
Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, Hicks JL, Morgan J, Cornish TC, Sutcliffe S, Isaacs WB, Luo J, De Marzo AM (2008) Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol 21:1156-1167
-
(2008)
Mod Pathol
, vol.21
, pp. 1156-1167
-
-
Gurel, B.1
Iwata, T.2
Koh, C.M.3
Jenkins, R.B.4
Lan, F.5
Van Dang, C.6
Hicks, J.L.7
Morgan, J.8
Cornish, T.C.9
Sutcliffe, S.10
Isaacs, W.B.11
Luo, J.12
De Marzo, A.M.13
-
23
-
-
31544466779
-
C-Myc overexpression causes anaplasia in medulloblastoma
-
10.1158/0008-5472.can-05-1580 16423996 10.1158/0008-5472.CAN-05-1580 1:CAS:528:DC%2BD28XlsFOltA%3D%3D
-
Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG (2006) c-Myc overexpression causes anaplasia in medulloblastoma. Cancer Res 66:673-681. doi: 10.1158/0008-5472.can-05-1580
-
(2006)
Cancer Res
, vol.66
, pp. 673-681
-
-
Stearns, D.1
Chaudhry, A.2
Abel, T.W.3
Burger, P.C.4
Dang, C.V.5
Eberhart, C.G.6
-
24
-
-
84876294049
-
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas
-
10.1111/j.1750-3639.2012.00630.x 22928601 10.1111/j.1750-3639.2012.00630. x
-
Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ (2013) Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathol 23:237-243. doi: 10.1111/j.1750-3639.2012.00630.x
-
(2013)
Brain Pathol
, vol.23
, pp. 237-243
-
-
Nguyen, D.N.1
Heaphy, C.M.2
De Wilde, R.F.3
Orr, B.A.4
Odia, Y.5
Eberhart, C.G.6
Meeker, A.K.7
Rodriguez, F.J.8
-
25
-
-
55849116363
-
Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: A comparative morphologic and molecular genetic study
-
18816605 10.1002/cncr.23899
-
Rodriguez F, Scheithauer B, Giannini C, Bryant S, Jenkins R (2008) Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: a comparative morphologic and molecular genetic study. Cancer 113:2779-2789
-
(2008)
Cancer
, vol.113
, pp. 2779-2789
-
-
Rodriguez, F.1
Scheithauer, B.2
Giannini, C.3
Bryant, S.4
Jenkins, R.5
-
26
-
-
33845289802
-
Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: Association with gleason score and chromosome 8p deletion
-
17108105 10.1158/0008-5472.CAN-06-0963 1:CAS:528:DC%2BD2sXivVyqs7k%3D
-
Bethel C, Faith D, Li X, Guan B, Hicks J, Lan F, Jenkins R, Bieberich C, De Marzo A (2006) Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with gleason score and chromosome 8p deletion. Cancer Res 66:10683-10690
-
(2006)
Cancer Res
, vol.66
, pp. 10683-10690
-
-
Bethel, C.1
Faith, D.2
Li, X.3
Guan, B.4
Hicks, J.5
Lan, F.6
Jenkins, R.7
Bieberich, C.8
De Marzo, A.9
-
27
-
-
80053229934
-
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes
-
10.1016/j.ajpath.2011.06.018 21888887 10.1016/j.ajpath.2011.06.018 1:CAS:528:DC%2BC3MXhsVSqtb3P
-
Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih Ie M, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, Taube JM, Rakheja D, Kurman RJ, Wu TC, Roden RB, Argani P, De Marzo AM, Terracciano L, Torbenson M, Meeker AK (2011) Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. Am J Pathol 179:1608-1615. doi: 10.1016/j.ajpath.2011.06. 018
-
(2011)
Am J Pathol
, vol.179
, pp. 1608-1615
-
-
Heaphy, C.M.1
Subhawong, A.P.2
Hong, S.M.3
Goggins, M.G.4
Montgomery, E.A.5
Gabrielson, E.6
Netto, G.J.7
Epstein, J.I.8
Lotan, T.L.9
Westra, W.H.10
Shih Ie, M.11
Iacobuzio-Donahue, C.A.12
Maitra, A.13
Li, Q.K.14
Eberhart, C.G.15
Taube, J.M.16
Rakheja, D.17
Kurman, R.J.18
Wu, T.C.19
Roden, R.B.20
Argani, P.21
De Marzo, A.M.22
Terracciano, L.23
Torbenson, M.24
Meeker, A.K.25
more..
-
28
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Chin L, Meyerson M (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068 http://www.nature.com/nature/journal/v455/n7216/suppinfo/nature07385-S1.html
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Chin, L.1
Meyerson, M.2
-
29
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
10.1126/science.1207313 21719641 10.1126/science.1207313 1:CAS:528:DC%2BC3MXovF2mtb8%3D
-
Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK, Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH, Maitra A, Papadopoulos N, Meeker AK (2011) Altered telomeres in tumors with ATRX and DAXX mutations. Science 333:425. doi: 10.1126/science. 1207313
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
De Wilde, R.F.2
Jiao, Y.3
Klein, A.P.4
Edil, B.H.5
Shi, C.6
Bettegowda, C.7
Rodriguez, F.J.8
Eberhart, C.G.9
Hebbar, S.10
Offerhaus, G.J.11
McLendon, R.12
Rasheed, B.A.13
He, Y.14
Yan, H.15
Bigner, D.D.16
Oba-Shinjo, S.M.17
Marie, S.K.18
Riggins, G.J.19
Kinzler, K.W.20
Vogelstein, B.21
Hruban, R.H.22
Maitra, A.23
Papadopoulos, N.24
Meeker, A.K.25
more..
-
30
-
-
84868625787
-
Frequent ATRX, CIC, and FUBP1 mutations refine the classification of malignant gliomas
-
22869205
-
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, He Y, Friedman H, Friedman AH, Riggins GJ, Holdhoff M, Burger P, McLendon R, Bigner DD, Vogelstein B, Meeker AK, Kinzler KW, Papadopoulos N, Diaz LA, Yan H (2012) Frequent ATRX, CIC, and FUBP1 mutations refine the classification of malignant gliomas. Oncotarget 3:709-722
-
(2012)
Oncotarget
, vol.3
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
Rasheed, A.B.4
Heaphy, C.M.5
De Wilde, R.F.6
Rodriguez, F.J.7
Rosemberg, S.8
Oba-Shinjo, S.M.9
Nagahashi Marie, S.K.10
Bettegowda, C.11
Agrawal, N.12
Lipp, E.13
Pirozzi, C.14
Lopez, G.15
He, Y.16
Friedman, H.17
Friedman, A.H.18
Riggins, G.J.19
Holdhoff, M.20
Burger, P.21
McLendon, R.22
Bigner, D.D.23
Vogelstein, B.24
Meeker, A.K.25
Kinzler, K.W.26
Papadopoulos, N.27
Diaz, L.A.28
Yan, H.29
more..
-
31
-
-
84876294049
-
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas
-
10.1111/j.1750-3639.2012.00630.x 22928601
-
Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ (2012) Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathol. doi: 10.1111/j.1750-3639.2012.00630.x
-
(2012)
Brain Pathol
-
-
Nguyen, D.N.1
Heaphy, C.M.2
De Wilde, R.F.3
Orr, B.A.4
Odia, Y.5
Eberhart, C.G.6
Meeker, A.K.7
Rodriguez, F.J.8
-
32
-
-
84860528433
-
IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma
-
10.1158/1078-0432.ccr-11-2977 22415316 10.1158/1078-0432.CCR-11-2977 1:CAS:528:DC%2BC38XmsFejurY%3D
-
Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT (2012) IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma. Clin Cancer Res 18:2490-2501. doi: 10.1158/1078-0432.ccr-11-2977
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2490-2501
-
-
Gorovets, D.1
Kannan, K.2
Shen, R.3
Kastenhuber, E.R.4
Islamdoust, N.5
Campos, C.6
Pentsova, E.7
Heguy, A.8
Jhanwar, S.C.9
Mellinghoff, I.K.10
Chan, T.A.11
Huse, J.T.12
-
33
-
-
47749130029
-
C-MYC amplification and expression in astrocytic tumors
-
18369647 10.1007/s00401-008-0368-0 1:CAS:528:DC%2BD1cXosVOjtL0%3D
-
Faria M, Khayat A, Burbano R, Rabenhorst S (2008) c-MYC amplification and expression in astrocytic tumors. Acta Neuropathol 116:87-95
-
(2008)
Acta Neuropathol
, vol.116
, pp. 87-95
-
-
Faria, M.1
Khayat, A.2
Burbano, R.3
Rabenhorst, S.4
-
34
-
-
33751292604
-
Expression of Ki-67, topoisomerase IIalpha; And c-MYC in astrocytic tumors: Correlation with the histopathological grade and proliferative status
-
17203587 10.1111/j.1440-1789.2006.00724.x
-
Faria MH, Gonçalves BP, do Patrocínio RM, de Moraes-Filho MO, Rabenhorst SH (2006) Expression of Ki-67, topoisomerase IIalpha; and c-MYC in astrocytic tumors: correlation with the histopathological grade and proliferative status. Neuropathology 26:519-527
-
(2006)
Neuropathology
, vol.26
, pp. 519-527
-
-
Faria, M.H.1
Gonçalves, B.P.2
Do Patrocínio, R.M.3
De Moraes-Filho, M.O.4
Rabenhorst, S.H.5
-
35
-
-
84886599648
-
Predictive value of IDH1 mutation assessed by immunohistochemistry and DNA sequencing in WHO grade 3 oligodendrogliomas
-
Abstract #2002
-
Frenel J, Leux C, Loussouarn D, Le Loupp A, Leclair F, Von Deimling A, Aumont M, Martin S, Denis MG, Campone M (2012) Predictive value of IDH1 mutation assessed by immunohistochemistry and DNA sequencing in WHO grade 3 oligodendrogliomas. ASCO Annual Meeting: Abstract #2002
-
(2012)
ASCO Annual Meeting
-
-
Frenel, J.1
Leux, C.2
Loussouarn, D.3
Le Loupp, A.4
Leclair, F.5
Von Deimling, A.6
Aumont, M.7
Martin, S.8
Denis, M.G.9
Campone, M.10
-
36
-
-
41749098048
-
The origins of medulloblastoma subtypes
-
10.1146/annurev.pathmechdis.3.121806.151518 18039127 10.1146/annurev. pathmechdis.3.121806.151518 1:CAS:528:DC%2BD1cXjsFersLo%3D
-
Gilbertson RJ, Ellison DW (2008) The origins of medulloblastoma subtypes. Annu Rev Pathol 3:341-365. doi: 10.1146/annurev.pathmechdis.3.121806.151518
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 341-365
-
-
Gilbertson, R.J.1
Ellison, D.W.2
-
37
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
10.1038/nature10866 22343889 10.1038/nature10866 1:CAS:528: DC%2BC38XisVKktLc%3D
-
Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA (2012) IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483:479-483. doi: 10.1038/nature10866
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
Walsh, L.A.4
Fang, F.5
Yilmaz, E.6
Campos, C.7
Fabius, A.W.8
Lu, C.9
Ward, P.S.10
Thompson, C.B.11
Kaufman, A.12
Guryanova, O.13
Levine, R.14
Heguy, A.15
Viale, A.16
Morris, L.G.17
Huse, J.T.18
Mellinghoff, I.K.19
Chan, T.A.20
more..
-
38
-
-
78549283855
-
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1
-
10.1158/0008-5472.CAN-10-1666 21045145 10.1158/0008-5472.CAN-10-1666 1:CAS:528:DC%2BC3cXhsVWmsL3N
-
Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, Dang CV, Riggins GJ (2010) Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res 70:8981-8987. doi: 10.1158/0008-5472.CAN-10-1666
-
(2010)
Cancer Res
, vol.70
, pp. 8981-8987
-
-
Seltzer, M.J.1
Bennett, B.D.2
Joshi, A.D.3
Gao, P.4
Thomas, A.G.5
Ferraris, D.V.6
Tsukamoto, T.7
Rojas, C.J.8
Slusher, B.S.9
Rabinowitz, J.D.10
Dang, C.V.11
Riggins, G.J.12
-
39
-
-
76749094506
-
High-risk medulloblastoma: Does c-myc amplification overrule histopathology?
-
20063409 10.1002/pbc.22398
-
Raabe EH, Eberhart CG (2010) High-risk medulloblastoma: does c-myc amplification overrule histopathology? Pediatr Blood Cancer 54:344-345
-
(2010)
Pediatr Blood Cancer
, vol.54
, pp. 344-345
-
-
Raabe, E.H.1
Eberhart, C.G.2
-
40
-
-
9744246805
-
Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas
-
10.1002/gcc.20108 15472895 10.1002/gcc.20108 1:CAS:528:DC%2BD2cXhtFGmsrfK
-
Kitange G, Misra A, Law M, Passe S, Kollmeyer TM, Maurer M, Ballman K, Feuerstein BG, Jenkins RB (2005) Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas. Genes Chromosomes Cancer 42:68-77. doi: 10.1002/gcc.20108
-
(2005)
Genes Chromosomes Cancer
, vol.42
, pp. 68-77
-
-
Kitange, G.1
Misra, A.2
Law, M.3
Passe, S.4
Kollmeyer, T.M.5
Maurer, M.6
Ballman, K.7
Feuerstein, B.G.8
Jenkins, R.B.9
-
41
-
-
80052608062
-
Mutations in CIC and FUBP1 contribute to human oligodendroglioma
-
10.1126/science.1210557 21817013 10.1126/science.1210557 1:CAS:528:DC%2BC3MXhtFWqurnF
-
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SKN, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW (2011) Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 333:1453-1455. doi: 10.1126/science.1210557
-
(2011)
Science
, vol.333
, pp. 1453-1455
-
-
Bettegowda, C.1
Agrawal, N.2
Jiao, Y.3
Sausen, M.4
Wood, L.D.5
Hruban, R.H.6
Rodriguez, F.J.7
Cahill, D.P.8
McLendon, R.9
Riggins, G.10
Velculescu, V.E.11
Oba-Shinjo, S.M.12
Marie, S.K.N.13
Vogelstein, B.14
Bigner, D.15
Yan, H.16
Papadopoulos, N.17
Kinzler, K.W.18
-
42
-
-
77953112103
-
Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR
-
20420426 10.1021/bi9021445 1:CAS:528:DC%2BC3cXlvFehu7k%3D
-
Hsiao HH, Nath A, Lin CY, Folta Stogniew E, Rhoades E, Braddock D (2010) Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR. Biochemistry 49:4620-4634
-
(2010)
Biochemistry
, vol.49
, pp. 4620-4634
-
-
Hsiao, H.H.1
Nath, A.2
Lin, C.Y.3
Folta Stogniew, E.4
Rhoades, E.5
Braddock, D.6
-
43
-
-
84865730529
-
A statin-regulated microRNA represses human c-Myc expression and function
-
10.1002/emmm.201101045 22887866 10.1002/emmm.201101045 1:CAS:528:DC%2BC38Xht1ylur3P
-
Takwi AA, Li Y, Becker Buscaglia LE, Zhang J, Choudhury S, Park AK, Liu M, Young KH, Park WY, Martin RC (2012) A statin-regulated microRNA represses human c-Myc expression and function. EMBO Mol Med 4:896-909. doi: 10.1002/emmm.201101045
-
(2012)
EMBO Mol Med
, vol.4
, pp. 896-909
-
-
Takwi, A.A.1
Li, Y.2
Becker Buscaglia, L.E.3
Zhang, J.4
Choudhury, S.5
Park, A.K.6
Liu, M.7
Young, K.H.8
Park, W.Y.9
Martin, R.C.10
-
44
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
10.1158/0008-5472.CAN-07-2462 17942906 10.1158/0008-5472.CAN-07-2462 1:CAS:528:DC%2BD2sXhtFOnsb%2FF
-
Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ (2007) MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 67:9762-9770. doi: 10.1158/0008-5472.CAN-07-2462
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
Yang, Q.4
Aris, V.5
Soteropoulos, P.6
Petrelli, N.J.7
Dunn, S.P.8
Krueger, L.J.9
-
45
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
10.1073/pnas.0803055105 18768788 10.1073/pnas.0803055105 1:CAS:528:DC%2BD1cXhtFeqs7bF
-
Lujambio A, Calin GA, Villanueva A, Ropero S, Sanchez-Cespedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM, Esteller M (2008) A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci USA 105:13556-13561. doi: 10.1073/pnas.0803055105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
Ropero, S.4
Sanchez-Cespedes, M.5
Blanco, D.6
Montuenga, L.M.7
Rossi, S.8
Nicoloso, M.S.9
Faller, W.J.10
Gallagher, W.M.11
Eccles, S.A.12
Croce, C.M.13
Esteller, M.14
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