메뉴 건너뛰기




Volumn 115, Issue 2, 2013, Pages 249-259

CMYC expression in infiltrating gliomas: Associations with IDH1 mutations, clinicopathologic features and outcome

Author keywords

Astrocytoma; cMYC; Glioblastoma; Gliomas; IDH1; IDH1 (R132H); Prognosis; Survival

Indexed keywords

ISOCITRATE DEHYDROGENASE 1; MYC PROTEIN; PROTEIN P53;

EID: 84886593066     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-013-1221-4     Document Type: Article
Times cited : (27)

References (45)
  • 1
    • 84868023931 scopus 로고    scopus 로고
    • CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2005-2009
    • 10.1093/neuonc/nos218 23095881 10.1093/neuonc/nos218
    • Dolecek TA, Propp JM, Stroup NE, Kruchko C (2012) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. Neuro Oncol 14:v1-v49. doi: 10.1093/neuonc/nos218
    • (2012) Neuro Oncol , vol.14
    • Dolecek, T.A.1    Propp, J.M.2    Stroup, N.E.3    Kruchko, C.4
  • 5
    • 70449518400 scopus 로고    scopus 로고
    • Monoclonal antibody specific for IDH-R132H mutation
    • 10.1007/s00401-009-0595-z 19798509 10.1007/s00401-009-0595-z 1:CAS:528:DC%2BD1MXhtlKitLrK
    • Capper D, Zentgraf H, Balss J, Hartmann C, von Deimling A (2009) Monoclonal antibody specific for IDH-R132H mutation. Acta Neuropathol 118:599-601. doi: 10.1007/s00401-009-0595-z
    • (2009) Acta Neuropathol , vol.118 , pp. 599-601
    • Capper, D.1    Zentgraf, H.2    Balss, J.3    Hartmann, C.4    Von Deimling, A.5
  • 7
    • 84867562009 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in tumorigenesis: Mechanistic insights and clinical perspectives
    • 10.1158/1078-0432.ccr-12-1773 23071358 10.1158/1078-0432.CCR-12-1773 1:CAS:528:DC%2BC38XhsFahu73E
    • Yang H, Ye D, Guan KL, Xiong Y (2012) IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives. Clin Cancer Res 18:5562-5571. doi: 10.1158/1078-0432.ccr-12-1773
    • (2012) Clin Cancer Res , vol.18 , pp. 5562-5571
    • Yang, H.1    Ye, D.2    Guan, K.L.3    Xiong, Y.4
  • 11
    • 78651082266 scopus 로고    scopus 로고
    • Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
    • 10.1007/s00401-010-0781-z 21088844 10.1007/s00401-010-0781-z
    • Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A (2010) Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 120:707-718. doi: 10.1007/s00401-010-0781-z
    • (2010) Acta Neuropathol , vol.120 , pp. 707-718
    • Hartmann, C.1    Hentschel, B.2    Wick, W.3    Capper, D.4    Felsberg, J.5    Simon, M.6    Westphal, M.7    Schackert, G.8    Meyermann, R.9    Pietsch, T.10    Reifenberger, G.11    Weller, M.12    Loeffler, M.13    Von Deimling, A.14
  • 12
    • 84867540151 scopus 로고    scopus 로고
    • C-Myc and cancer metabolism
    • 10.1158/1078-0432.ccr-12-0977 23071356 10.1158/1078-0432.CCR-12-0977 1:CAS:528:DC%2BC38XhsFahu73K
    • Miller DM, Thomas SD, Islam A, Muench D, Sedoris K (2012) c-Myc and cancer metabolism. Clin Cancer Res 18:5546-5553. doi: 10.1158/1078-0432.ccr-12- 0977
    • (2012) Clin Cancer Res , vol.18 , pp. 5546-5553
    • Miller, D.M.1    Thomas, S.D.2    Islam, A.3    Muench, D.4    Sedoris, K.5
  • 13
    • 56849131763 scopus 로고    scopus 로고
    • C-Myc is required for maintenance of glioma cancer stem cells
    • 10.1371/journal.pone.0003769 19020659 10.1371/journal.pone.0003769
    • Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN (2008) c-Myc is required for maintenance of glioma cancer stem cells. PLoS One 3:e3769. doi: 10.1371/journal.pone.0003769
    • (2008) PLoS One , vol.3 , pp. 3769
    • Wang, J.1    Wang, H.2    Li, Z.3    Wu, Q.4    Lathia, J.D.5    McLendon, R.E.6    Hjelmeland, A.B.7    Rich, J.N.8
  • 15
    • 70350728803 scopus 로고    scopus 로고
    • MYC-induced cancer cell energy metabolism and therapeutic opportunities
    • 10.1158/1078-0432.CCR-09-0889 19861459 10.1158/1078-0432.CCR-09-0889 1:CAS:528:DC%2BD1MXhtlCjsrnM
    • Dang CV, Le A, Gao P (2009) MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res 15:6479-6483. doi: 10.1158/1078-0432.CCR-09-0889
    • (2009) Clin Cancer Res , vol.15 , pp. 6479-6483
    • Dang, C.V.1    Le, A.2    Gao, P.3
  • 16
    • 84865313576 scopus 로고    scopus 로고
    • Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
    • 22360810 10.1111/j.1755-148X.2012.00989.x 1:CAS:528:DC%2BC38XpsFOmsbY%3D
    • Filipp F, Scott D, Ronai ZA, Osterman A, Smith J (2012) Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells. Pigment Cell Melanoma Res 25:375-383
    • (2012) Pigment Cell Melanoma Res , vol.25 , pp. 375-383
    • Filipp, F.1    Scott, D.2    Ronai, Z.A.3    Osterman, A.4    Smith, J.5
  • 18
    • 83755178091 scopus 로고    scopus 로고
    • Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
    • 22106302 10.1073/pnas.1117773108 1:CAS:528:DC%2BC3MXhs1GjsbvP
    • Wise D, Ward P, Shay JES, Cross J, Gruber J, Sachdeva U, Platt J, DeMatteo R, Simon MC, Thompson C (2011) Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci USA 108:19611-19616
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19611-19616
    • Wise, D.1    Ward, P.2    Shay, J.E.S.3    Cross, J.4    Gruber, J.5    Sachdeva, U.6    Platt, J.7    Dematteo, R.8    Simon, M.C.9    Thompson, C.10
  • 19
    • 70350217425 scopus 로고    scopus 로고
    • Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling
    • 10.1158/0008-5472.can-09-2266 19826036 10.1158/0008-5472.CAN-09-2266 1:CAS:528:DC%2BD1MXht1ynurbK
    • Yang C, Sudderth J, Dang T, Bachoo RG, McDonald JG, DeBerardinis RJ (2009) Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res 69:7986-7993. doi: 10.1158/0008-5472.can-09-2266
    • (2009) Cancer Res , vol.69 , pp. 7986-7993
    • Yang, C.1    Sudderth, J.2    Dang, T.3    Bachoo, R.G.4    McDonald, J.G.5    Deberardinis, R.J.6
  • 23
    • 31544466779 scopus 로고    scopus 로고
    • C-Myc overexpression causes anaplasia in medulloblastoma
    • 10.1158/0008-5472.can-05-1580 16423996 10.1158/0008-5472.CAN-05-1580 1:CAS:528:DC%2BD28XlsFOltA%3D%3D
    • Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG (2006) c-Myc overexpression causes anaplasia in medulloblastoma. Cancer Res 66:673-681. doi: 10.1158/0008-5472.can-05-1580
    • (2006) Cancer Res , vol.66 , pp. 673-681
    • Stearns, D.1    Chaudhry, A.2    Abel, T.W.3    Burger, P.C.4    Dang, C.V.5    Eberhart, C.G.6
  • 24
    • 84876294049 scopus 로고    scopus 로고
    • Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas
    • 10.1111/j.1750-3639.2012.00630.x 22928601 10.1111/j.1750-3639.2012.00630. x
    • Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ (2013) Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathol 23:237-243. doi: 10.1111/j.1750-3639.2012.00630.x
    • (2013) Brain Pathol , vol.23 , pp. 237-243
    • Nguyen, D.N.1    Heaphy, C.M.2    De Wilde, R.F.3    Orr, B.A.4    Odia, Y.5    Eberhart, C.G.6    Meeker, A.K.7    Rodriguez, F.J.8
  • 25
    • 55849116363 scopus 로고    scopus 로고
    • Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: A comparative morphologic and molecular genetic study
    • 18816605 10.1002/cncr.23899
    • Rodriguez F, Scheithauer B, Giannini C, Bryant S, Jenkins R (2008) Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: a comparative morphologic and molecular genetic study. Cancer 113:2779-2789
    • (2008) Cancer , vol.113 , pp. 2779-2789
    • Rodriguez, F.1    Scheithauer, B.2    Giannini, C.3    Bryant, S.4    Jenkins, R.5
  • 26
    • 33845289802 scopus 로고    scopus 로고
    • Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: Association with gleason score and chromosome 8p deletion
    • 17108105 10.1158/0008-5472.CAN-06-0963 1:CAS:528:DC%2BD2sXivVyqs7k%3D
    • Bethel C, Faith D, Li X, Guan B, Hicks J, Lan F, Jenkins R, Bieberich C, De Marzo A (2006) Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with gleason score and chromosome 8p deletion. Cancer Res 66:10683-10690
    • (2006) Cancer Res , vol.66 , pp. 10683-10690
    • Bethel, C.1    Faith, D.2    Li, X.3    Guan, B.4    Hicks, J.5    Lan, F.6    Jenkins, R.7    Bieberich, C.8    De Marzo, A.9
  • 28
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Chin L, Meyerson M (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068 http://www.nature.com/nature/journal/v455/n7216/suppinfo/nature07385-S1.html
    • (2008) Nature , vol.455 , pp. 1061-1068
    • Chin, L.1    Meyerson, M.2
  • 31
    • 84876294049 scopus 로고    scopus 로고
    • Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas
    • 10.1111/j.1750-3639.2012.00630.x 22928601
    • Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ (2012) Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathol. doi: 10.1111/j.1750-3639.2012.00630.x
    • (2012) Brain Pathol
    • Nguyen, D.N.1    Heaphy, C.M.2    De Wilde, R.F.3    Orr, B.A.4    Odia, Y.5    Eberhart, C.G.6    Meeker, A.K.7    Rodriguez, F.J.8
  • 33
    • 47749130029 scopus 로고    scopus 로고
    • C-MYC amplification and expression in astrocytic tumors
    • 18369647 10.1007/s00401-008-0368-0 1:CAS:528:DC%2BD1cXosVOjtL0%3D
    • Faria M, Khayat A, Burbano R, Rabenhorst S (2008) c-MYC amplification and expression in astrocytic tumors. Acta Neuropathol 116:87-95
    • (2008) Acta Neuropathol , vol.116 , pp. 87-95
    • Faria, M.1    Khayat, A.2    Burbano, R.3    Rabenhorst, S.4
  • 34
    • 33751292604 scopus 로고    scopus 로고
    • Expression of Ki-67, topoisomerase IIalpha; And c-MYC in astrocytic tumors: Correlation with the histopathological grade and proliferative status
    • 17203587 10.1111/j.1440-1789.2006.00724.x
    • Faria MH, Gonçalves BP, do Patrocínio RM, de Moraes-Filho MO, Rabenhorst SH (2006) Expression of Ki-67, topoisomerase IIalpha; and c-MYC in astrocytic tumors: correlation with the histopathological grade and proliferative status. Neuropathology 26:519-527
    • (2006) Neuropathology , vol.26 , pp. 519-527
    • Faria, M.H.1    Gonçalves, B.P.2    Do Patrocínio, R.M.3    De Moraes-Filho, M.O.4    Rabenhorst, S.H.5
  • 36
    • 41749098048 scopus 로고    scopus 로고
    • The origins of medulloblastoma subtypes
    • 10.1146/annurev.pathmechdis.3.121806.151518 18039127 10.1146/annurev. pathmechdis.3.121806.151518 1:CAS:528:DC%2BD1cXjsFersLo%3D
    • Gilbertson RJ, Ellison DW (2008) The origins of medulloblastoma subtypes. Annu Rev Pathol 3:341-365. doi: 10.1146/annurev.pathmechdis.3.121806.151518
    • (2008) Annu Rev Pathol , vol.3 , pp. 341-365
    • Gilbertson, R.J.1    Ellison, D.W.2
  • 39
    • 76749094506 scopus 로고    scopus 로고
    • High-risk medulloblastoma: Does c-myc amplification overrule histopathology?
    • 20063409 10.1002/pbc.22398
    • Raabe EH, Eberhart CG (2010) High-risk medulloblastoma: does c-myc amplification overrule histopathology? Pediatr Blood Cancer 54:344-345
    • (2010) Pediatr Blood Cancer , vol.54 , pp. 344-345
    • Raabe, E.H.1    Eberhart, C.G.2
  • 40
    • 9744246805 scopus 로고    scopus 로고
    • Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas
    • 10.1002/gcc.20108 15472895 10.1002/gcc.20108 1:CAS:528:DC%2BD2cXhtFGmsrfK
    • Kitange G, Misra A, Law M, Passe S, Kollmeyer TM, Maurer M, Ballman K, Feuerstein BG, Jenkins RB (2005) Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas. Genes Chromosomes Cancer 42:68-77. doi: 10.1002/gcc.20108
    • (2005) Genes Chromosomes Cancer , vol.42 , pp. 68-77
    • Kitange, G.1    Misra, A.2    Law, M.3    Passe, S.4    Kollmeyer, T.M.5    Maurer, M.6    Ballman, K.7    Feuerstein, B.G.8    Jenkins, R.B.9
  • 42
    • 77953112103 scopus 로고    scopus 로고
    • Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR
    • 20420426 10.1021/bi9021445 1:CAS:528:DC%2BC3cXlvFehu7k%3D
    • Hsiao HH, Nath A, Lin CY, Folta Stogniew E, Rhoades E, Braddock D (2010) Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR. Biochemistry 49:4620-4634
    • (2010) Biochemistry , vol.49 , pp. 4620-4634
    • Hsiao, H.H.1    Nath, A.2    Lin, C.Y.3    Folta Stogniew, E.4    Rhoades, E.5    Braddock, D.6
  • 44
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • 10.1158/0008-5472.CAN-07-2462 17942906 10.1158/0008-5472.CAN-07-2462 1:CAS:528:DC%2BD2sXhtFOnsb%2FF
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ (2007) MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 67:9762-9770. doi: 10.1158/0008-5472.CAN-07-2462
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6    Petrelli, N.J.7    Dunn, S.P.8    Krueger, L.J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.