Xerophilusin b induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma cells and does not cause toxicity in nude mice

Journal of Natural Products

Volumn 78, Issue 1, 2015, Pages 10-16

  Yao, Ran ^a   Chen, Zhaoli ^a   Zhou, Chengcheng ^a   Luo, Mei ^a   Shi, Xuejiao ^a   Li, Jiagen ^a   Gao, Yibo ^a   Zhou, Fang ^a   Pu, Jianxin ^b   Sun, Handong ^b   He, Jie ^a  

^a CANCER HOSPITAL   (China)

^b KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CISPLATIN; CYTOCHROME C; DITERPENOID; UNCLASSIFIED DRUG; XEROPHILUSIN B; DITERPENE; KAURANE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BALB/C NUDE MOUSE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG MEGADOSE; ENZYME ACTIVATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; HUMAN; HUMAN CELL; IC50; IN VIVO STUDY; ISODON; LOW DRUG DOSE; MOUSE; NONHUMAN; SQUAMOUS CELL CARCINOMA CELL; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, SQUAMOUS CELL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ESOPHAGEAL NEOPLASMS; G2 PHASE CELL CYCLE CHECKPOINT; ISOLATION AND PURIFICATION; METABOLISM; NUDE MOUSE; WESTERN BLOTTING;

ISODON XEROPHILUS; MURINAE; MUS MUSCULUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CASPASE 9; DITERPENES; DITERPENES, KAURANE; ESOPHAGEAL NEOPLASMS; FEMALE; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; ISODON; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR STRUCTURE;

EID: 84921629563     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np500429w     Document Type: Article

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