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Volumn 14, Issue 1, 2014, Pages

Anti-hepatotoxic activities of Hibiscus sabdariffa L. In animal model of streptozotocin diabetes-induced liver damage

Author keywords

Antioxidant; Diabetes mellitus; Flavonoids; Hibiscus sabdariffa; Liver; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; FLAVONOID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLYCOGEN; HIBISCUS SABDARIFFA EXTRACT; PLASMA PROTEIN; STREPTOZOCIN; SUPEROXIDE DISMUTASE; ENZYME; PLANT EXTRACT; PROTECTIVE AGENT;

EID: 84905908563     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-277     Document Type: Article
Times cited : (65)

References (52)
  • 1
    • 3242659967 scopus 로고    scopus 로고
    • Liver disease and diabetes mellitus
    • Levinthal GN, Tavill AS. Liver disease and diabetes mellitus. Clin Diabetes 1999, 17(2):73-93.
    • (1999) Clin Diabetes , vol.17 , Issue.2 , pp. 73-93
    • Levinthal, G.N.1    Tavill, A.S.2
  • 2
    • 0032983139 scopus 로고    scopus 로고
    • Development of phytomedicine for liver diseases
    • Subramoniam A, Pushpangadan P. Development of phytomedicine for liver diseases. Ind J Pharmacol 1999, 31:166-175.
    • (1999) Ind J Pharmacol , vol.31 , pp. 166-175
    • Subramoniam, A.1    Pushpangadan, P.2
  • 7
    • 0034525045 scopus 로고    scopus 로고
    • Changes in liver gangliosides in streptozotocin-induced diabetic rats
    • 11114239
    • Sanchez SS, Abregu AV, Aybar MJ, Sanchez Riera AN. Changes in liver gangliosides in streptozotocin-induced diabetic rats. Cell Biol Int 2000, 24:897-904. 10.1006/cbir.1999.0452, 11114239.
    • (2000) Cell Biol Int , vol.24 , pp. 897-904
    • Sanchez, S.S.1    Abregu, A.V.2    Aybar, M.J.3    Sanchez Riera, A.N.4
  • 8
    • 3042548559 scopus 로고    scopus 로고
    • The morphological and biochemical effects of glibornuride on rat liver in experimental diabetes
    • 15228018
    • Bolkent S, Yanardag R, Karabulut-Bulan O, Ozsoy-Sacan O. The morphological and biochemical effects of glibornuride on rat liver in experimental diabetes. Hum Exp Toxicol 2004, 23:257-264. 10.1191/0960327104ht444oa, 15228018.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 257-264
    • Bolkent, S.1    Yanardag, R.2    Karabulut-Bulan, O.3    Ozsoy-Sacan, O.4
  • 9
    • 20444468073 scopus 로고    scopus 로고
    • Effects of vanadyl sulfate on liver of streptozotocin-induced diabetic rats
    • 15930593
    • Koyuturk M, Tunali S, Bolkent S, Yanardag R. Effects of vanadyl sulfate on liver of streptozotocin-induced diabetic rats. Biol Trace Elem Res 2005, 104:233-247. 10.1385/BTER:104:3:233, 15930593.
    • (2005) Biol Trace Elem Res , vol.104 , pp. 233-247
    • Koyuturk, M.1    Tunali, S.2    Bolkent, S.3    Yanardag, R.4
  • 10
  • 11
    • 0025121370 scopus 로고
    • Prevention of thioacetamide-induced hepatotoxicity by biflavanones of Garcinia kola
    • Iwu MM, Igboko OA, Elekwa OK, Tempesta MS. Prevention of thioacetamide-induced hepatotoxicity by biflavanones of Garcinia kola. Phytother Res 1990, 4:157-159.
    • (1990) Phytother Res , vol.4 , pp. 157-159
    • Iwu, M.M.1    Igboko, O.A.2    Elekwa, O.K.3    Tempesta, M.S.4
  • 12
    • 0027485312 scopus 로고
    • Perfusion with picroliv reverses biochemical changes induced in livers of rats toxicated with galactosamine or thioacetamide
    • 8255934
    • Dwivedi Y, Rastogi R, Garg NK, Dhawan BN. Perfusion with picroliv reverses biochemical changes induced in livers of rats toxicated with galactosamine or thioacetamide. Planta Med 1993, 59:418-420. 10.1055/s-2006-959722, 8255934.
    • (1993) Planta Med , vol.59 , pp. 418-420
    • Dwivedi, Y.1    Rastogi, R.2    Garg, N.K.3    Dhawan, B.N.4
  • 13
    • 34250848241 scopus 로고    scopus 로고
    • Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus
    • 1624823, 17040567
    • Lans CA. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus. J Ethnobiol Ethnomed 2006, 2:45. 10.1186/1746-4269-2-45, 1624823, 17040567.
    • (2006) J Ethnobiol Ethnomed , vol.2 , pp. 45
    • Lans, C.A.1
  • 14
    • 33845970583 scopus 로고    scopus 로고
    • Mechanisms of the antihypertensive effect of Hibiscus sabdariffa L. calyces
    • 16973321
    • Ajay M, Chai HJ, Mustafa AM, Gilani AH, Mustafa MR. Mechanisms of the antihypertensive effect of Hibiscus sabdariffa L. calyces. J Ethnopharmacol 2007, 109(3):388-393. 10.1016/j.jep.2006.08.005, 16973321.
    • (2007) J Ethnopharmacol , vol.109 , Issue.3 , pp. 388-393
    • Ajay, M.1    Chai, H.J.2    Mustafa, A.M.3    Gilani, A.H.4    Mustafa, M.R.5
  • 16
    • 29144478796 scopus 로고    scopus 로고
    • Hypocholesterolemic and antioxidant effects of aqueosus extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholesterolemic rats
    • 16213683
    • Hirunpanich V, Utaipat A, Morales NP, Bunyapraphatssara N, Sato H, Herunsale A, Suthisisang C. Hypocholesterolemic and antioxidant effects of aqueosus extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholesterolemic rats. J Ethnopharmacol 2006, 103:252-260. 10.1016/j.jep.2005.08.033, 16213683.
    • (2006) J Ethnopharmacol , vol.103 , pp. 252-260
    • Hirunpanich, V.1    Utaipat, A.2    Morales, N.P.3    Bunyapraphatssara, N.4    Sato, H.5    Herunsale, A.6    Suthisisang, C.7
  • 17
    • 36348962914 scopus 로고    scopus 로고
    • Hypolipidaemic and antioxidant effects of ethanolic extract from dried calyx of Hibiscus sabdariffa in alloxan-induced diabetic rats
    • 18034661
    • Farombi EO, Ige OO. Hypolipidaemic and antioxidant effects of ethanolic extract from dried calyx of Hibiscus sabdariffa in alloxan-induced diabetic rats. Fundam Clin Pharmacol 2007, 21(6):601-609. 10.1111/j.1472-8206.2007.00525.x, 18034661.
    • (2007) Fundam Clin Pharmacol , vol.21 , Issue.6 , pp. 601-609
    • Farombi, E.O.1    Ige, O.O.2
  • 20
    • 0036230951 scopus 로고    scopus 로고
    • In-vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
    • 11955669
    • Liu CL, Wang JM, Chu CY, Cheng MT, Tseng TH. In-vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity. Food Chem Toxicol 2002, 40(5):635-641. 10.1016/S0278-6915(02)00002-9, 11955669.
    • (2002) Food Chem Toxicol , vol.40 , Issue.5 , pp. 635-641
    • Liu, C.L.1    Wang, J.M.2    Chu, C.Y.3    Cheng, M.T.4    Tseng, T.H.5
  • 21
    • 0034030162 scopus 로고    scopus 로고
    • Protective effect of Hibiscus anthocyanins against tertbutyl hydroperoxide-induced hepatic toxicity in rats
    • 10762726
    • Wang CJ, Wang JM, Lin WL, Chu CY, Chou FP, Tseng TH. Protective effect of Hibiscus anthocyanins against tertbutyl hydroperoxide-induced hepatic toxicity in rats. Food Chem Toxicol 2000, 38(5):411-416. 10.1016/S0278-6915(00)00011-9, 10762726.
    • (2000) Food Chem Toxicol , vol.38 , Issue.5 , pp. 411-416
    • Wang, C.J.1    Wang, J.M.2    Lin, W.L.3    Chu, C.Y.4    Chou, F.P.5    Tseng, T.H.6
  • 22
    • 0037275439 scopus 로고    scopus 로고
    • The effect of a water extract and anthocyanins of Hibiscus sabdariffa L. on paracetamol-induced hepatoxicity in rats
    • 12557248
    • Ali BH, Mousa HM, El-Mougy S. The effect of a water extract and anthocyanins of Hibiscus sabdariffa L. on paracetamol-induced hepatoxicity in rats. Phytother Res 2003, 17(1):56-59. 10.1002/ptr.1084, 12557248.
    • (2003) Phytother Res , vol.17 , Issue.1 , pp. 56-59
    • Ali, B.H.1    Mousa, H.M.2    El-Mougy, S.3
  • 23
    • 84984580675 scopus 로고    scopus 로고
    • Acetaminophen-induced liver damage in mice: Effects of some medicinal plants on the oxidative defense system
    • 18054472
    • Olaleye MT, Joa¨o-Rocha BT. Acetaminophen-induced liver damage in mice: Effects of some medicinal plants on the oxidative defense system. Exp Toxicol Pathol 2008, 59(5):319-329. 10.1016/j.etp.2007.10.003, 18054472.
    • (2008) Exp Toxicol Pathol , vol.59 , Issue.5 , pp. 319-329
    • Olaleye, M.T.1    Joa¨o-Rocha, B.T.2
  • 24
    • 67649547144 scopus 로고    scopus 로고
    • Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminophen-induced liver damage in mice
    • 19459732
    • Choi JH, Chul YC, Lee KJ, Hwang PL, Chung YC, Jeong HG. Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminophen-induced liver damage in mice. J Med Food 2009, 12(2):320-326. 10.1089/jmf.2007.0691, 19459732.
    • (2009) J Med Food , vol.12 , Issue.2 , pp. 320-326
    • Choi, J.H.1    Chul, Y.C.2    Lee, K.J.3    Hwang, P.L.4    Chung, Y.C.5    Jeong, H.G.6
  • 25
    • 0003633755 scopus 로고    scopus 로고
    • Washington DC: National Academy Press, 7, National Research Council (NRC) Institute of Laboratory Animal Research (ILAR)
    • National Research Council (NRC) Institute of Laboratory Animal Research (ILAR) Guide for the Care and Use of Laboratory Animals 1996, 259. Washington DC: National Academy Press, 7, National Research Council (NRC) Institute of Laboratory Animal Research (ILAR).
    • (1996) Guide for the Care and Use of Laboratory Animals , pp. 259
  • 26
    • 80052032320 scopus 로고    scopus 로고
    • Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of Phytochemicals and biological activities
    • 21741462
    • Wangchuk P, Keller PA, Pyne SG, Taweechotipatr M, Tonsomboon A, Rattanajak R, Kamchonwongpaisan S. Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of Phytochemicals and biological activities. J Ethnopharmacol 2011, 137:730-742. 10.1016/j.jep.2011.06.032, 21741462.
    • (2011) J Ethnopharmacol , vol.137 , pp. 730-742
    • Wangchuk, P.1    Keller, P.A.2    Pyne, S.G.3    Taweechotipatr, M.4    Tonsomboon, A.5    Rattanajak, R.6    Kamchonwongpaisan, S.7
  • 27
    • 0342982310 scopus 로고    scopus 로고
    • Acute intraperitoneal toxicity (LD50) and target organ effects of aqueous extract of Trigonella foenumgraceum leaf in the mouse
    • Abdel-Barry JA, Al-Hakiem MHH, Abdel-Hassan IA. Acute intraperitoneal toxicity (LD50) and target organ effects of aqueous extract of Trigonella foenumgraceum leaf in the mouse. Basrah J Sci 1997, 58:C58-C65.
    • (1997) Basrah J Sci , vol.58 , pp. C58-C65
    • Abdel-Barry, J.A.1    Al-Hakiem, M.H.H.2    Abdel-Hassan, I.A.3
  • 29
    • 77953940707 scopus 로고    scopus 로고
    • Histomorphological and morphometric studies of the pancreatic islet cells of diabetic rats treated with extracts of Annona muricata
    • Adeyemi DO, Komolafe OA, Adewole OS, Obuotor EM, Abiodun AA, Adenowo TK. Histomorphological and morphometric studies of the pancreatic islet cells of diabetic rats treated with extracts of Annona muricata. Folia Morphol 2010, 69(2):92-100.
    • (2010) Folia Morphol , vol.69 , Issue.2 , pp. 92-100
    • Adeyemi, D.O.1    Komolafe, O.A.2    Adewole, O.S.3    Obuotor, E.M.4    Abiodun, A.A.5    Adenowo, T.K.6
  • 31
    • 0000526378 scopus 로고
    • A simple method for the silver impregnation of reticulin
    • 1911089, 19970284
    • Gordon H, Sweet HH. A simple method for the silver impregnation of reticulin. Am J Pathol 1936, 12:545. 1911089, 19970284.
    • (1936) Am J Pathol , vol.12 , pp. 545
    • Gordon, H.1    Sweet, H.H.2
  • 32
    • 0028293739 scopus 로고
    • The rapid potentiometric detection of catalase positive microorganisms
    • 8018314
    • Cowell DC, Dowman AA, Lewis RJ, Pirzad R, Watkins SD. The rapid potentiometric detection of catalase positive microorganisms. Biosens Bioelectron 1994, 9(2):131-138. 10.1016/0956-5663(94)80104-5, 8018314.
    • (1994) Biosens Bioelectron , vol.9 , Issue.2 , pp. 131-138
    • Cowell, D.C.1    Dowman, A.A.2    Lewis, R.J.3    Pirzad, R.4    Watkins, S.D.5
  • 35
    • 33744986316 scopus 로고    scopus 로고
    • Poly (ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death
    • 1482814, 16526943
    • Blenn C, Althaus FR, Malanga M. Poly (ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death. Biochem J 2006, 396:419-429. 10.1042/BJ20051696, 1482814, 16526943.
    • (2006) Biochem J , vol.396 , pp. 419-429
    • Blenn, C.1    Althaus, F.R.2    Malanga, M.3
  • 36
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • 36810
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358. 10.1016/0003-2697(79)90738-3, 36810.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 38
    • 18144377715 scopus 로고    scopus 로고
    • Glycaemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes
    • 15855556
    • Cook MN, Girman CJ, Stein PP, Alexander CM, Holman RR. Glycaemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes. Diabetes Care 2005, 28:995-1000. 10.2337/diacare.28.5.995, 15855556.
    • (2005) Diabetes Care , vol.28 , pp. 995-1000
    • Cook, M.N.1    Girman, C.J.2    Stein, P.P.3    Alexander, C.M.4    Holman, R.R.5
  • 39
    • 52649169064 scopus 로고    scopus 로고
    • β-cell failure in type 2 diabetes mellitus
    • 18625113
    • Cristina L, Roberto L, Stefano DP. β-cell failure in type 2 diabetes mellitus. Curr Diab Rep 2008, 8:179-184. 10.1007/s11892-008-0031-0, 18625113.
    • (2008) Curr Diab Rep , vol.8 , pp. 179-184
    • Cristina, L.1    Roberto, L.2    Stefano, D.P.3
  • 40
    • 1842423094 scopus 로고    scopus 로고
    • The role of oxidative stress in diabetic complications
    • Baynes JW, Thorpe SR. The role of oxidative stress in diabetic complications. Curr Opin Endocrinol 1999, 3:277-284.
    • (1999) Curr Opin Endocrinol , vol.3 , pp. 277-284
    • Baynes, J.W.1    Thorpe, S.R.2
  • 41
    • 29344463658 scopus 로고    scopus 로고
    • Free radical scavenging and antigenotoxic activities of natural phenolic compounds in dried flowers of Hibiscus sabdariffa L
    • Farombi EO, Fakoya A. Free radical scavenging and antigenotoxic activities of natural phenolic compounds in dried flowers of Hibiscus sabdariffa L. Mol Nutr Food Res 2005, 49(12):11208.
    • (2005) Mol Nutr Food Res , vol.49 , Issue.12 , pp. 11208
    • Farombi, E.O.1    Fakoya, A.2
  • 42
    • 78650460293 scopus 로고    scopus 로고
    • Hibiscus sabdariffa L: source of antioxidant dietary fiber
    • Sa´yago-Ayerdi SG, Goñi I. Hibiscus sabdariffa L: source of antioxidant dietary fiber. Arch Latinoam Nutr 2010, 60(1):79-84.
    • (2010) Arch Latinoam Nutr , vol.60 , Issue.1 , pp. 79-84
    • Sa´yago-Ayerdi, S.G.1    Goñi, I.2
  • 43
    • 70849115327 scopus 로고    scopus 로고
    • Aqueous extract of Hibiscus sabdariffa L. decelerates acetaminophen-induced acute liver damage by reducing cell death and oxidative stress in mouse experimental models
    • 20355050
    • Liu LC, Wang CJ, Lee CC, Su SC, Chen HL, Hsu JD, Lee HJ. Aqueous extract of Hibiscus sabdariffa L. decelerates acetaminophen-induced acute liver damage by reducing cell death and oxidative stress in mouse experimental models. J Sci Food Agric 2010, 90:329-337. 10.1002/jsfa.3821, 20355050.
    • (2010) J Sci Food Agric , vol.90 , pp. 329-337
    • Liu, L.C.1    Wang, C.J.2    Lee, C.C.3    Su, S.C.4    Chen, H.L.5    Hsu, J.D.6    Lee, H.J.7
  • 44
    • 0035691617 scopus 로고    scopus 로고
    • The Mechanism of Alloxan and Streptozotocin Action in B cells of the Rat Pancreas
    • Szkudelski T. The Mechanism of Alloxan and Streptozotocin Action in B cells of the Rat Pancreas. Physiol Res 2001, 50:536-546.
    • (2001) Physiol Res , vol.50 , pp. 536-546
    • Szkudelski, T.1
  • 45
    • 2942511430 scopus 로고    scopus 로고
    • Effect of sodium molybdate on the status of lipids, lipid peroxidation and antioxidant systems in alloxan-induced diabetic rats
    • 15193982
    • Panneerselvam SR, Govindasamy S. Effect of sodium molybdate on the status of lipids, lipid peroxidation and antioxidant systems in alloxan-induced diabetic rats. Clin Chim Acta 2004, 345:93-98. 10.1016/j.cccn.2004.03.005, 15193982.
    • (2004) Clin Chim Acta , vol.345 , pp. 93-98
    • Panneerselvam, S.R.1    Govindasamy, S.2
  • 46
    • 0031434221 scopus 로고    scopus 로고
    • Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes
    • 9449221
    • Tseng TH, Kao ES, Chu CY, Chou FP, Lin Wu HW, Wang CJ. Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes. Food Chem Toxicol 1997, 35(12):1159-1164. 10.1016/S0278-6915(97)85468-3, 9449221.
    • (1997) Food Chem Toxicol , vol.35 , Issue.12 , pp. 1159-1164
    • Tseng, T.H.1    Kao, E.S.2    Chu, C.Y.3    Chou, F.P.4    Lin Wu, H.W.5    Wang, C.J.6
  • 47
    • 0036841865 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: the high risk patient
    • Nissen NN, Martin P. Hepatocellular carcinoma: the high risk patient. J Clin Gastroenterol 2002, 35(Suppl. 2):S79-S85.
    • (2002) J Clin Gastroenterol , vol.35 , pp. S79-S85
    • Nissen, N.N.1    Martin, P.2
  • 48
    • 0036297389 scopus 로고    scopus 로고
    • Current strategies for chemoprevention of hepatocellular carcinoma
    • 11868781
    • Okita K, Sakaida I, Hino K. Current strategies for chemoprevention of hepatocellular carcinoma. Oncology 2002, 62(Suppl. 1):24-28. 10.1159/000048272, 11868781.
    • (2002) Oncology , vol.62 , pp. 24-28
    • Okita, K.1    Sakaida, I.2    Hino, K.3
  • 49
    • 28844451168 scopus 로고    scopus 로고
    • The protective effects of Hibiscus sabdariffa extract on CCl4-induced liver fibrosis in rats
    • 16176854
    • Liu JY, Chen CC, Wang WH, Hsu JD, Yang MY, Wang CJ. The protective effects of Hibiscus sabdariffa extract on CCl4-induced liver fibrosis in rats. Food Chem Toxicol 2006, 44:336-343. 10.1016/j.fct.2005.08.003, 16176854.
    • (2006) Food Chem Toxicol , vol.44 , pp. 336-343
    • Liu, J.Y.1    Chen, C.C.2    Wang, W.H.3    Hsu, J.D.4    Yang, M.Y.5    Wang, C.J.6
  • 50
    • 0030583290 scopus 로고    scopus 로고
    • Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes
    • 8760395
    • Tseng TH, Wang CJ, Kao ES, Chu HY. Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes. Chem Biol Interact 1996, 101(2):137-148. 10.1016/0009-2797(96)03721-0, 8760395.
    • (1996) Chem Biol Interact , vol.101 , Issue.2 , pp. 137-148
    • Tseng, T.H.1    Wang, C.J.2    Kao, E.S.3    Chu, H.Y.4
  • 51
    • 67650687104 scopus 로고    scopus 로고
    • Hatem Masmoudi and Abdelfattah Elfeki Therapeutic effect of phytoecdysteroids rich extract from Ajuga iva on alloxan induced diabetic rats liver, kidney and pancreas
    • Hamden K, Ayadi F, Jamoussi K. Hatem Masmoudi and Abdelfattah Elfeki Therapeutic effect of phytoecdysteroids rich extract from Ajuga iva on alloxan induced diabetic rats liver, kidney and pancreas. Bio Factors 2008, 33:165-175.
    • (2008) Bio Factors , vol.33 , pp. 165-175
    • Hamden, K.1    Ayadi, F.2    Jamoussi, K.3
  • 52
    • 79961215502 scopus 로고    scopus 로고
    • Effects of aqueous extract of Hibiscus sabdariffa L. calyces on liver marker enzymes of phenobarbitone-induced adult wistar albino rats
    • Ubani CS, Joshua PE, Anieke UC. Effects of aqueous extract of Hibiscus sabdariffa L. calyces on liver marker enzymes of phenobarbitone-induced adult wistar albino rats. J Chem Pharm Res 2011, 3(4):528-537.
    • (2011) J Chem Pharm Res , vol.3 , Issue.4 , pp. 528-537
    • Ubani, C.S.1    Joshua, P.E.2    Anieke, U.C.3


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