PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1

Biochemical Journal

Volumn 461, Issue 3, 2014, Pages 383-390

  Oppelt, Angela ^a,b   Haugsten, Ellen M ^a,b   Zech, Tobias ^c   Danielsen, Håvard E ^a,b   Sveen, Anita ^a,d   Lobert, Viola H ^a,b   Skotheim, Rolf I ^a,d   Wesche, Jørgen ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Analysis software; Cell migration; Gene expression; Myotubularin related protein 3 (MTMR3); PIKfyve; PtdIns5P

Indexed keywords

MYOTUBULARIN RELATED PROTEIN 3; PHOSPHATIDYLINOSITIDE; PHOSPHOINOSITIDE 5 KINASE; PHOSPHOINOSITIDE PTDINS5P; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CANCER CELL; CANCER CELL LINE; CELL DIVISION; CELL INVASION; CELL MEMBRANE; CELL MIGRATION; CELL MOTILITY; CELL POLARITY; CELL PROLIFERATION; CELL SHAPE; CELL TRACKING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

CARCINOMA; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CELL POLARITY; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; ENZYME ACTIVATION; ENZYME INHIBITORS; EXPERT SYSTEMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; RAC1 GTP-BINDING PROTEIN; RNA INTERFERENCE; SARCOMA; SOFTWARE;

EID: 84904110070     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140132     Document Type: Article

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