Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells

Journal of Immunology

Volumn 182, Issue 7, 2009, Pages 3974-3978

  Guittard, Geoffrey ^a,b,c   Gérard, Audrey ^a,b,c   Dupuis Coronas, Sophie ^d   Tronchère, Hélène ^d   Mortier, Eva ^e   Favre, Cédric ^a,b,c   Olive, Daniel ^a,b,c   Zimmermann, Pascale ^e   Payrastre, Bernard ^d   Nunès, Jacques A ^a,b,c  

^a INSERM   (France)

^b INSTITUT PAOLI CALMETTES   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

^e UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PROTEIN DOK 1; PROTEIN DOK 2; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DOK1 PROTEIN, HUMAN; DOK2 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 5-PHOSPHATE; PHOSPHOPROTEIN; POLYPHOSPHOINOSITIDE; RNA BINDING PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; BIOSYNTHESIS; HELA CELL; IMMUNOLOGY; LEUKEMIA CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; SURFACE PLASMON RESONANCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; PHOSPHORYLATION; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; T-LYMPHOCYTES;

EID: 64249093846     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804172     Document Type: Article

References (23)

1. Acuto, O., V. D. Bartolo, and F. Michel. 2008. Tailoring T-cell receptor signals by proximal negative feedback mechanisms. Nat. Rev. Immunol. 8: 699-712.
2. Yang, W. C., M. Ghiotto, B. Barbarat, and D. Olive. 1999. The role of Tec protein-tyrosine kinase in T cell signaling. J. Biol. Chem. 274: 607-617. (Pubitemid 129535214)
3. Dong, S., B. Corre, E. Foulon, E. Dufour, A. Veillette, O. Acuto, and F. Michel. 2006. T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2. J. Exp. Med. 203: 2509-2518. (Pubitemid 44664620)
4. Gérard, A., C. Favre, F. Garcon, J. G. Némorin, P. Duplay, S. Pastor, Y. Collette, D. Olive, and J. A. Nunès. 2004. Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase. Oncogene 23: 1594-1598.
5. Némorin, J. G., P. Laporte, G. Berube, and P. Duplay. 2001. p62dok negatively regulates CD2 signaling in Jurkat cells. J. Immunol. 166: 4408-4415.
6. Yasuda, T., K. Bundo, A. Hino, K. Honda, A. Inoue, M. Shirakata, M. Osawa, T. Tamura, H. Nariuchi, H. Oda, et al. 2007. Dok-1 and Dok-2 are negative regulators of T cell receptor signaling. Int. Immunol. 19: 487-495. (Pubitemid 46523396)
7. Lemmon, M. A. 2007. Pleckstrin homology (PH) domains and phosphoinositides. Biochem. Soc. Symp. 74: 81-93.
8. Pendaries, C., H. Tronchère, M. Plantavid, and B. Payrastre. 2003. Phosphoinositide signaling disorders in human diseases. FEBS Lett. 546: 25-31. (Pubitemid 36782278)
9. Lemmon, M. A. 2008. Membrane recognition by phospholipid-binding domains. Nat. Rev. Mol. Cell Biol. 9: 99-111.
10. Rameh, L. E., K. F. Tolias, B. C. Duckworth, and L. C. Cantley. 1997. A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 390: 192-196.
11. Coronas, S., D. Ramel, C. Pendaries, F. Gaits-Iacovoni, H. Tronchère, and B. Payrastre. 2007. PtdIns5P: a little phosphoinositide with big functions? Biochem. Soc. Symp. 74: 117-128.
12. Niebuhr, K., S. Giuriato, T. Pedron, D. J. Philpott, F. Gaits, J. Sable, M. P. Sheetz, C. Parsot, P. J. Sansonetti, and B. Payrastre. 2002. Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S. flexneri effector IpgD reorganizes host cell morphology. EMBO J. 21: 5069-5078.
13. Pendaries, C., H. Tronchère, L. Arbibe, J. Mounier, O. Gozani, L. Cantley, M. J. Fry, F. Gaits-Iacovoni, P. J. Sansonetti, and B. Payrastre. 2006. PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection. EMBO J. 25: 1024-1034.
14. Coronas, S., F. Lagarrigue, D. Ramel, G. Chicanne, G. Delsol, B. Payrastre, and H. Tronchère. 2008. Elevated levels of PtdIns5P in NPM-ALK transformed cells: implication of PIKfyve. Biochem. Biophys. Res. Commun. 372: 351-355.
15. Wilcox, A., and K. A. Hinchliffe. 2008. Regulation of extranuclear PtdIns5P production by phosphatidylinositol phosphate 4-kinase 2α. FEBS Lett. 582: 1391-1394.
16. Gozani, O., P. Karuman, D. R. Jones, D. Ivanov, J. Cha, A. A. Lugovskoy, C. L. Baird, H. Zhu, S. J. Field, S. L. Lessnick, et al. 2003. The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell 114: 99-111. (Pubitemid 36859844)
17. Mortier, E., G. Wuytens, I. Leenaerts, F. Hannes, M. Y. Heung, G. Degeest, G. David, and P. Zimmermann. 2005. Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions. EMBO J. 24: 2556-2565. (Pubitemid 41076312)
18. Nunès, J., S. Klasen, M. Ragueneau, C. Pavon, D. Couez, C. Mawas, M. Bagnasco, and D. Olive. 1993. CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events. Int. Immunol. 5: 311-315. (Pubitemid 23093169)
19. dok is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. J. Exp. Med. 194: 265-274.
20. Park, W. S., W. D. Heo, J. H. Whalen, N. A. O'Rourke, H. M. Bryan, T. Meyer, and M. N. Teruel. 2008. Comprehensive identification of PIP3-regulated PH domains from C. elegans to H. sapiens by model prediction and live imaging. Mol. Cell 30: 381-392.
21. Clarke, J. H., A. J. Letcher, S. D'Santos, C. J. R. Halstead, R. F. Irvine, and N. Divecha. 2001. Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells. Biochem. J. 357: 905-910.
22. Sbrissa, D., O. C. Ikonomov, R. Deeb, and A. Shisheva. 2002. Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells. J. Biol. Chem. 277: 47276-47284. (Pubitemid 36159239)
23. Tronchère, H., J. Laporte, C. Pendaries, C. Chaussade, L. Liaubet, L. Pirola, J. L. Mandel, and B. Payrastre. 2004. Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells. J. Biol. Chem. 279: 7304-7312. (Pubitemid 38248880)