A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides

Biochemical Journal

Volumn 428, Issue 3, 2010, Pages 375-384

  Sarkes, Deborah ^a   Rameh, Lucia E ^a  

^a BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

HPLC; Phosphoinositide; PtdIns5P; PtdIns5P 4 kinase; Subcellular fractionation; Vesicle transport

Indexed keywords

ACCURATE MEASUREMENT; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; HPLC METHOD; INSULIN SECRETION; INTRACELLULAR MEMBRANES; LIGHT FRACTION; MYOBLASTS; PANCREATIC CELL LINES; PHOSPHOINOSITIDES; PLASMA MEMBRANES; SPATIAL CHARACTERIZATION; SUBCELLULAR FRACTIONATION; VESICLE TRAFFICKING; VESICLE TRANSPORT;

CELL CULTURE; CELL MEMBRANES; PHOSPHOLIPIDS; PHOSPHORIC ACID;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

BREFELDIN A; PHOSPHATIDYLINOSITIDE; PTEN LIKE PHOSPHOINOSITIDE 5 PHOSPHATASE; UNCLASSIFIED DRUG; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PHOSPHATIDYLINOSITOL 5-PHOSPHATE; POLYPHOSPHOINOSITIDE;

ACCURACY; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; FIBROBLAST; GOLGI COMPLEX; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INSULIN RELEASE; INTRACELLULAR MEMBRANE; MOUSE; MYOBLAST; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REPRODUCIBILITY; SMOOTH ENDOPLASMIC RETICULUM; ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL STRAIN 3T3; CHEMISTRY; CHO CELL; CRICETULUS; HAMSTER; METABOLISM; METHODOLOGY;

ANIMALS; CELL MEMBRANE; CELLS, CULTURED; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; HELA CELLS; HUMANS; MICE; NIH 3T3 CELLS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHATIDYLINOSITOLS;

EID: 77954930785     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100129     Document Type: Article

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