Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P 2 by means of the PIKfyve inhibitor YM201636

American Journal of Physiology - Cell Physiology

Volumn 303, Issue 4, 2012, Pages

  Sbrissa, Diego ^a   Ikonomov, Ognian C ^a   Filios, Catherine ^a   Delvecchio, Khortnal ^a   Shisheva, Assia ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dok proteins; Insulin regulated F actin disassembly; Insulin regulated GLUT4 translocation; Phosphoinositide profiles; Vacuolation phenotype

Indexed keywords

ACTIN; GLUCOSE TRANSPORTER 4; INSULIN; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PROTEIN SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG; YM 201636;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRESS; CELL VACUOLE; CHO CELL; CONTROLLED STUDY; DISSOCIATION; DRUG EFFICACY; DRUG POTENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MOUSE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; STRESS FIBER;

3T3-L1 CELLS; AMINOPYRIDINES; ANIMALS; CHO CELLS; CRICETINAE; DNA-BINDING PROTEINS; HEK293 CELLS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; INSULIN; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; RNA-BINDING PROTEINS;

EID: 84865140750     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00105.2012     Document Type: Article

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