Carbon monoxide may be an important molecule In migraine and other headaches

Cephalalgia

Volumn 34, Issue 14, 2014, Pages 1169-1180

  Arngrim, Nanna ^a   Schytz, Henrik W ^a   Hauge, Mette K ^a   Ashina, Messoud ^a   Olesen, Jes ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Carbon monoxide; Cerebral vessels; Haeme oxygenase; Headache; Pain processing

Indexed keywords

CARBON MONOXIDE; CARBOXYHEMOGLOBIN; NEUROTRANSMITTER;

ARTERY TONE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN OXYGEN TENSION; CARBON MONOXIDE INTOXICATION; HEADACHE; HUMAN; HYPERBARIC OXYGEN; MIGRAINE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PHYSICAL ACTIVITY; REVIEW; ANIMAL; METABOLISM;

ANIMALS; CARBON MONOXIDE; HUMANS; MIGRAINE DISORDERS;

EID: 84921516686     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102414534085     Document Type: Review

References (89)

1. Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013;33:629-808.
2. Stewart RD, Peterson JE, Baretta ED, et al. Experimental human exposure to carbon monoxide. Arch Env Heal 1970;21:154-164.
3. Stewart RD, Fisher TN, Baretta ED, et al. Experimental human exposure to high concentrations of carbon monoxide. Arch Env Heal 1973;26:1-7.
4. Hampson NB and Hampson LA. Characteristics of headache associated with acute carbon monoxide poisoning. Headache 2002;42:220-223.
5. Haldane J. Medicolegal contributions of historical interest. The action of carbonic oxide on man. Forensic Sci 1972;1:451-483.
6. Stewart RD. The effect of carbon monoxide on humans. J Occup Med 1975;18:304-309.
7. Heckerling PS. Occult carbon monoxide poisoning: A cause of winter headache. Am J Emerg Med 1987;5:201-204.
8. Piantadosi CA. Biological chemistry of carbon monoxide. Antioxid Redox Signal 2002;4:259-270.
9. Uddman R, Tajti J, Sundler F, et al. The presence of heme-oxygenase and biliverdin reductase in human cranial ganglia indicates a role for carbon monoxide in neural transmission. Neuro Endocrinol Lett 2004;25:423-428.
10. Verma A, Hirsch DJ, Glatt CE, et al. Carbon monoxide: A putative neural messenger. Science 1993;259:381-384.
11. Maines MD. The heme oxygenase system: A regulator of second messenger gases. Annu Rev Pharmacol Toxicol 1997;37:517-554.
12. Olesen J. The role of nitric oxide (NO) in migraine, tensiontype headache and cluster headache. Pharmacol Ther 2008;120:157-171.
13. Leffler CW, Parfenova H, Fedinec AL, et al. Contributions of astrocytes and CO to pial arteriolar dilation to glutamate in newborn pigs. Am J Physiol Heart Circ Physiol 2006;291:H2897-H2904.
14. Kanu A and Leffler CW. Arachidonic acid- and prostaglandin E2-induced cerebral vasodilation is mediated by carbon monoxide, independent of reactive oxygen species in piglets. Am J Physiol Heart Circ Physiol 2011;301:H2482-H2487.
15. Li A, Xi Q, Umstot ES, et al. Astrocyte-derived CO is a diffusible messenger that mediates glutamate-induced cerebral arteriolar dilation by activating smooth muscle Cell KCa channels. Cir Res 2008;102:234-241.
16. D'Amico G, Lam F, Hagen T, et al. Inhibition of cellular respiration by endogenously produced carbon monoxide. J Cell Sci 2006;119:2291-2298.
17. Piantadosi CA, Zhang J and Demchenko IT. Production of hydroxyl radical in the hippocampus after CO hypoxia or hypoxic hypoxia in the rat. Free Radic Biol Med 1997;22:725-732.
18. Rodkey FL, O'Neal JD, Collison HA, et al. Relative affinity of hemoglobin S and hemoglobin A for carbon monoxide and oxygen. Clin Chem 1974;20:83-84.
19. Roughton F JW and Darling RC. The effect of carbon monoxide on the oxyhemoglobin dissociation curve. Am J Physiol 1944;141:17-31.
20. Okada Y and Tyuma I. Effect of carbon monoxide on equilibrium between oxygen and hemoglobin. Am J Physiol 1976;230:471-475.
21. Goldbaum LR. Mechanism of the toxic action of carbon monoxide. Ann Clin Lab Sci 1976;6:372-376.
22. Linderholm H. On the significance of CO tension in pulmonary capillary blood for determination of pulmonary diffusing capacity with the steady state CO method. Acta Med Scand 1957;156:413-427.
23. Magnusson S, Ekström TJ, Elmér E, et al. Heme oxygenase-1, heme oxygenase-2 and biliverdin reductase in peripheral ganglia from rat, expression and plasticity. Neuroscience 2000;95:821-829.
24. Scapagnini G, D'Agata V, Calabrese V, et al. Gene expression profiles of heme oxygenase isoforms in the rat brain. Brain Res 2002;954:51-59.
25. Ewing JF and Maines MD. In situ hybridization and immunohistochemical localization of heme oxygenase-2 mRNA and protein in normal rat brain: Differential distribution of isozyme 1 and 2. Mol Cell Neurosci 1992;3:559-570.
26. Leffler CW, Nasjletti A, Yu C, et al. Carbon monoxide and cerebral microvascular tone in newborn pigs. Am J Physiol 1999;276:H1641-H1646.
27. Vollerthun R, Höhler B and Kummer W. Heme oxygenase-2 in primary afferent neurons of the guinea-pig. Histochem Cell Biol 1996;105:453-458.
28. Olesen J, Burstein R, Ashina M, et al. Origin of pain in migraine: Evidence for peripheral sensitisation. Lancet Neurol 2009;8:679-690.
29. Lassen LH, Haderslev PA, Jacobsen VB, et al. CGRP may play a causative role in migraine. Cephalalgia 2002;22:54-61.
30. Gordh T, Sharma HS, Azizi M, et al. Spinal nerve lesion induces upregulation of constitutive isoform of heme oxygenase in the spinal cord. An immunohistochemical investigation in the rat. Amino Acids 2000;19:373-381.
31. Li X and Clark JD. The role of heme oxygenase in neuropathic and incisional pain. Anesth Analg 2000;90:677-682.
32. Li X and Clark JD. Heme oxygenase type 2 plays a role in formalin-induced nociception. Pain 2000;86:75-80.
33. Li X and Clark JD. Spinal cord heme oxygenase participates in glutamate-induced pain-related behaviors. Eur J Pharmacol 2002;450:43-48.
34. Li X and Clark JD. Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain. J Pain 2003;4:101-107.
35. Yachie A, Niida Y, Wada T, et al. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J Clin Invest 1999;103:129-135.
36. Li X and Clark JD. Heme oxygenase inhibitors reduce formalin-induced Fos expression in mouse spinal cord tissue. Neuroscience 2001;105:949-956.
37. Li X, Lighthall G, Liang DY, et al. Alterations in spinal cord gene expression after hindpaw formalin injection. J Neurosci Res 2004;78:533-541.
38. Steiner AA, Branco LG, Cunha FQ, et al. Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity. Br J Pharmacol 2001;132:1673-1682.
39. Nascimento CG and Branco LG. Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway. Braz J Med Biol Res 2009;42:141-147.
40. Hervera A, Leánez S, Negrete R, et al. Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice. PLoS One 2012;7:e43693.
41. Morita T, Perrella MA, Lee ME, et al. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci U SA 1995;92:1475-1479.
42. Li X and Clark JD. Spinal cord nitric oxide synthase and heme oxygenase limit morphine induced analgesia. Brain Res Mol Brain Res 2001;95:96-102.
43. Piantadosi CA, Zhang J, Levin ED, et al. Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat. Exp Neurol 1997;147:103-114.
44. Shinomura T, Nakao S and Mori K. Reduction of depolarizationinduced glutamate release by heme oxygenase inhibitor: Possible role of carbon monoxide in synaptic transmission. Neurosci Lett 1994;166:131-134.
45. Paulson OB, Parving HH, Olesen J, et al. Influence of carbon monoxide and of hemodilution on cerebral blood flow and blood gases in man. J Appl Physiol 1973;35:111-116.
46. Benignus VA, Petrovick MK, Newlin-Clapp L, et al. Carboxyhemoglobin and brain blood flow in humans. Neurotoxicol Teratol 1992;14:285-290.
47. Komuro T, Borsody MK, Ono S, et al. The vasorelaxation of cerebral arteries by carbon monoxide. Exp Biol Med 2001;226:860-865.
48. Andresen JJ, Shafi NI, Durante W, et al. Effects of carbon monoxide and heme oxygenase inhibitors in cerebral vessels of rats and mice. Am J Physiol Heart Circ Physiol 2006;291:H223-H230.
49. Amin FM, Asghar MS, Hougaard A, et al. Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: A cross-sectional study. Lancet Neurol 2013;12:454-461.
50. Achouh PE, Simonet S, Fabiani JN, et al. Carbon monoxide induces relaxation of human internal thoracic and radial arterial grafts. Interact Cardiovasc Thorac Surg 2008;7:959-962.
51. Wang R, Wang Z and Wu L. Carbon monoxide-induced vasorelaxation and the underlying mechanisms. Br J Pharmacol 1997;121:927-934.
52. Leffler CW, Fedinec AL, Parfenova H, et al. Permissive contributions of NO and prostacyclin in CO-induced cerebrovascular dilation in piglets. Am J Physiol Heart Circ Physiol 2005;289:H432-H438.
53. Leffler CW, Nasjletti A, Johnson RA, et al. Contributions of prostacyclin and nitric oxide to carbon monoxideinduced cerebrovascular dilation in piglets. Am J Physiol Heart Circ Physiol 2001;280:H1490-H1495.
54. Barkoudah E, Jaggar JH and Leffler CW. The permissive role of endothelial NO in CO-induced cerebrovascular dilation. Am J Physiol Heart Circ Physiol 2004;287:H1459-H1465.
55. Kanu A and Leffler CW. Roles of glia limitans astrocytes and carbon monoxide in adenosine diphosphate-induced pial arteriolar dilation in newborn pigs. Stroke 2009;40:930-935.
56. Xi Q, Tcheranova D, Basuroy S, et al. Glutamateinduced calcium signals stimulate CO production in piglet astrocytes. Am J Physiol Heart Circ Physiol 2011;301:H428-H433.
57. Milligan ED and Watkins LR. Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci 2009;10:23-36.
58. Ishikawa M, Kajimura M, Adachi T, et al. Carbon monoxide from heme oxygenase-2 is a tonic regulator against NO-dependent vasodilatation in the adult rat cerebral microcirculation. Circ Res 2005;97:e104-e114.
59. Knecht KR, Milam S, Wilkinson DA, et al. Time-dependent action of carbon monoxide on the newborn cerebrovascular circulation. Am J Physiol Heart Circ Physiol 2010;299:H70-H75.
60. Ashina M, Bendtsen L, Jensen R, et al. Nitric oxideinduced headache in patients with chronic tension-type headache. Brain 2000;123:1830-1837.
61. Ekbom K. Nitrolglycerin as a provocative agent in cluster headache. Arch Neurol 1968;19:487-493.
62. Iversen HK, Olesen J and Tfelt-Hansen P. Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics. Pain 1989;38:17-24.
63. Lassen LH, Ashina M, Christiansen I, et al. Nitric oxide synthase inhibition in migraine. Lancet 1997;349:401-402.
64. Cooper CE and Brown GC. The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: Chemical mechanism and physiological significance. J Bioenerg Biomembr 2008;40:533-539.
65. Durante W, Kroll MH, Christodoulides N, et al. Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ Res 1997;80:557-564.
66. Polte T, Abate A, Dennery P, et al. Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide. Arterioscler Thromb Vasc Biol 2000;20:1209-1215.
67. White KA and Marletta MA. Nitric oxide synthase is a cytochrome P-450 type hemoprotein. Biochemistry 1992;31:6627-6631.
68. Zuckerbraun BS, Billiar TR, Otterbein SL, et al. Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. J Exp Med 2003;198:1707-1716.
69. Zuckerbraun BS, Chin BY, Wegiel B, et al. Carbon monoxide reverses established pulmonary hypertension. J Exp Med 2006;203:2109-2119.
70. Thorup C, Jones CL, Gross SS, et al. Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS. Am J Physiol 1999;277:F882-F889.
71. Ischiropoulos H, Beers MF, Ohnishi ST, et al. Nitric oxide production and perivascular nitration in brain after carbon monoxide poisoning in the rat. J Clin Invest 1996;97:2260-2267.
72. Bernecker C, Ragginer C, Fauler G, et al. Oxidative stress is associated with migraine and migraine-related metabolic risk in females. Eur J Neurol 2011;18:1233-1239.
73. Brown SD and Piantadosi CA. In vivo binding of carbon monoxide to cytochrome c oxidase in rat brain. J Appl Physiol (1985) 1990;68:604-610.
74. Brown SD and Piantadosi CA. Recovery of energy metabolism in rat brain after carbon monoxide hypoxia. J Clin Invest 1992;89:666-672.
75. Thom SR. Dehydrogenase conversion to oxidase and lipid peroxidation in brain after carbon monoxide poisoning. J Appl Physiol (1985) 1992;73:1584-1589.
76. Zhang J and Piantadosi CA. Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain. J Clin Invest 1992;90:1193-1199.
77. Thom SR, Xu YA and Ischiropoulos H. Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure. Chem Res Toxicol 1997;10:1023-1031.
78. Burney RE, Wu SC and Nemiroff MJ. Mass carbon monoxide poisoning: Clinical effects and results of treatment in 184 victims. Ann Emerg Med 1982;11:394-399.
79. Heckerling PS, Leikin JB, Maturen A, et al. Predictors of occult carbon monoxide poisoning in patients with headache and dizziness. Ann Intern Med 1987;107:174-176.
80. Sayers RR, Meriwether FV and Yant WP. Physiological effects of exposure to low concentrations of carbon monoxide. Public Health Rep 1922;19:1127-1142.
81. Hampson NB and Dunn SL. Symptoms of carbon monoxide poisoning do not correlate with the initial carboxyhemoglobin level. Undersea Hyperb Med 2012;39:657-665.
82. Schytz HW, Schoonman GG and Ashina M. What have we learnt from triggering migraine? Curr Opin Neurol 2010;23:259-265.
83. Raub JA and Benignus VA. Carbon monoxide and the nervous system. Neurosci Biobehav Rev 2002;26:925-940.
84. Salhofer-Polanyi S, Frantal S, Brannath W, et al. Prospective analysis of factors related to migraine aura - the PAMINA study. Headache 2012;52:1236-1245.
85. Lampl C, Voelker M and Steiner TJ. Aspirin is first-line treatment for migraine and episodic tension-type headache regardless of headache intensity. Headache 2012;52:48-56.
86. Ely EW, Moorehead B and Haponik EF. Warehouse workers' headache: Emergency evaluation and management of 30 patients with carbon monoxide poisoning. Am J Med 1995;98:145-155.
87. González-Alonso J. Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery: Role of circulating ATP. Circ Res 2002;91:1046-1055.
88. González-Alonso J, Richardson RS and Saltin B. Exercising skeletal muscle blood flow in humans responds to reduction in arterial oxyhaemoglobin, but not to altered free oxygen. J Physiol 2001;530:331-341.
89. Hanada A, Sander M and González-Alonso J. Human skeletal muscle sympathetic nerve activity, heart rate and limb haemodynamics with reduced blood oxygenation and exercise. J Physiol 2003;551:635-647.