Spinal cord nitric oxide synthase and heme oxygenase limit morphine induced analgesia

Molecular Brain Research

Volumn 95, Issue 1-2, 2001, Pages 96-102

  Li, Xiangqi ^a   Clark, J David ^a  

^a VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

cGMP; Heme oxygenase; Hyperalgesia; Morphine; Nitric oxide synthase; Null mutant

Indexed keywords

6 ANILINO 5,8 QUINOLINEQUINONE; 8 BROMO CYCLIC GMP; CARBON MONOXIDE; CYCLIC GMP; GUANYLATE CYCLASE; HEME OXYGENASE; HEME OXYGENASE INHIBITOR; MORPHINE; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NALOXONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; HOT PLATE TEST; HYPERALGESIA; MALE; METABOLISM; MOUSE; NONHUMAN; PAIN; PRIORITY JOURNAL; SPINAL ANESTHESIA; SPINAL CORD; TISSUE DISTRIBUTION;

ANALGESICS, OPIOID; ANIMALS; CYCLIC GMP; HEME OXYGENASE (DECYCLIZING); MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PAIN MEASUREMENT; SPINAL CORD;

EID: 0035500727     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00251-0     Document Type: Article

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