Alterations in spinal cord gene expression after hindpaw formalin injection

Journal of Neuroscience Research

Volumn 78, Issue 4, 2004, Pages 533-541

  Li, Xiangqi ^b   Lighthall, Geoff ^b   Liang, De Yong ^b   Clark, J David ^a,b,c  

^a Vet Aff Palo Alto Hlth Care Syst ^*  (United States)

^b STANFORD UNIVERSITY   (United States)

^c APAHCS   (United States)

Author keywords

Heme oxygenase; Inflammatory; Mice; Pain; PCR

Indexed keywords

ACTIVITY RELATED CYTOSKELETAL PROTEIN; BILIVERDIN; CARBON MONOXIDE; CELL PROTEIN; FORMALDEHYDE; HEME OXYGENASE 2; IRON; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; NERVE GROWTH FACTOR; PROTEIN C FOS; PROTEIN C JUN; RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME MECHANISM; GENE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; INFLAMMATION; INJECTION; LASER CAPTURE MICRODISSECTION; MALE; MOUSE; NGFI A GENE; NGFI B GENE; NOCICEPTION; NONHUMAN; ONCOGENE C FOS; PAIN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FORMALDEHYDE; FUNCTIONAL LATERALITY; GENE EXPRESSION; HEME OXYGENASE (DECYCLIZING); HINDLIMB; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRODISSECTION; MITOGEN-ACTIVATED PROTEIN KINASES; PAIN; PROTO-ONCOGENES; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINAL CORD; TIME FACTORS;

EID: 8844251503     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20274     Document Type: Article

References (45)

1. Alkadhi KA, Al-Hijailan RS, Malik K, Hogan YH. 2001. Retrograde carbon monoxide is required for induction of long-term potentiation in rat superior cervical ganglion. J Neurosci 21:3515-3520.
2. Allen S, Heath PR, Kirby J, Wharton SB, Cookson MR, Menzies FM, Banks RE, Shaw PJ. 2003. Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses, and nitric oxide synthetic pathways. J Biol Chem 278:6371-6383.
3. Basbaum AI. 1999. Spinal mechanisms of acute and persistent pain. Reg Anesth Pain Med 24:59-67.
4. Bolay H, Moskowitz MA. 2002. Mechanisms of pain modulation in chronic syndromes. Neurology 59(Suppl.):2-7.
5. Calza L, Pozza M, Zanni M, Manzini CU, Manzini E, Hokfelt T. 1998. Peptide plasticity in primary sensory neurons and spinal cord during adjuvant-induced arthritis in the rat: an immunocytochemical and in situ hybridization study. Neuroscience 82:575-589.
6. Csillik B, Janka Z, Boncz I, Kalman J, Mihaly A, Vecsei L, Knyihar E. 2003. Molecular plasticity of primary nociceptive neurons: relations of the NGF-c-jun system to neurotomy and chronic pain. Ann Anat 185:303-314.
7. Dwyer DE, Nishimura RN, Lu SY. 1995. Differential localization of heme oxygenase and NADPH-diaphorase in spinal cord neurons. Neuroreport 6:973-976.
8. Feldman AL, Costouros NG, Wang E, Qian M, Marincola FM, Alexander HR, Libutti SK. 2002. Advantages of mRNA amplification for microarray analysis. Biotechniques 33:906-912, 914.
9. Galan A, Cervero F, Laird JM. 2003. Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain. Brain Res Mol Brain Res 116:126-134.
10. Galan A, Lopez-Garcia JA, Cervero F, Laird JM. 2002. Activation of spinal extracellular signaling-regulated kinase-1 and -2 by intraplantar carrageenan in rodents. Neurosci Lett 322:37-40.
11. Hawkins RD, Zhuo M, Arancio O. 1994. Nitric oxide and carbon monoxide as possible retrograde messengers in hippocampal long-term potentiation. J Neurobiol 25:652-665.
12. Heath PR, Tomkins J, Ince PG, Shaw PJ. 2002. Quantitative assessment of AMPA receptor mRNA in human spinal motor neurons isolated by laser capture microdissection. Neuroreport 13:1753-1757.
13. Hou WY, Shyu BC, Chen TM, Lee JW, Shieh JY, Sun WZ. 1997. Intrathecally administered c-fos antisense oligodeoxynucleotide decreases formalin-induced nociceptive behavior in adult rats. Eur J Pharmacol 329:17-26.
14. Hunter JC, Woodburn VL, Durieux C, Pettersson EK, Poat JA, Hughes J. 1995. c-fos antisense oligodeoxynucleotide increases formalin-induced nociception and regulates preprodynorphin expression. Neuroscience 65:485-492.
15. Ji RR, Baba H, Brenner GJ, Woolf CJ. 1999. Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2:1114-1119.
16. Ji RR, Before K, Brenner GJ, Woolf CJ. 2002. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J Neurosci 22:478-485.
17. Lan CY, Tan PH, Cheng JT, Lu HF, Lin MW, Hsiao PN, Lin CR. 2003. Immunoneutralization of c-Fos using intrathecal antibody electroporation attenuates chronic constrictive injury-induced hyperalgesia and regulates preprodynorphin expression in rats. Anesthesiology 99:938-946.
18. Lavand'homme PM, Ma W, De Kock M, Eisenach JC. 2002. Perineural alpha(2A)-adrenoceptor activation inhibits spinal cord neuroplasticity and tactile allodynia after nerve injury. Anesthesiology 97:972-980.
19. Li X, Clark JD. 2000a. Heme oxygenase type 2 plays a role in formalin-induced nociception. Pain 86:75-80.
20. Li X, Clark JD. 2000b. The role of heme oxygenase in neuropathic and incisional pain. Anesth Analg 90:677-682.
21. Li X, Clark JD. 2001a. Heme oxygenase inhibitors reduce formalin-induced Fos expression in mouse spinal cord tissue. Neuroscience 105:949-956.
22. Li X, Clark JD. 2001b. Spinal cord nitric oxide synthase and heme oxygenase limit morphine induced analgesia. Brain Res Mol Brain Res 95:96-102.
23. Li X, Clark JD. 2002. Spinal cord heme oxygenase participates in glutamate-induced pain-related behaviors. Eur J Pharmacol 450:43-48.
24. Li X, Clark JD. 2003. Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain. J Pain 4:101-107.
25. Liang D, Li X, Clark JD. 2004. Increased expression of Ca(2+)/calmodulin-dependent protein kinase IIalpha during chronic morphine exposure. Neuroscience 123:769-775.
26. Liang D, Li X, Lighthall G, Clark JD. 2003. Heme oxygenase type 2 modulates behavioral and molecular changes during chronic exposure to morphine. Neuroscience 121:999-1005.
27. Liu Y, Obata K, Yamanaka H, Dai Y, Fukuoka T, Tokunaga A, Noguchi K. 2004. Activation of extracellular signal-regulated protein kinase in dorsal horn neurons in the rat neuropathic intermittent claudication model. Pain 109:64-72.
28. Lloyd RV, Jin L, Ruebel KH, Bayliss JM. 2002. Analysis of folliculostellate cells by laser capture microdissection and reverse transcription-polymerase chain reaction (LCM-RT/PCR). Methods Enzymol 356:248-255.
29. Lucas JJ, Mellstrom B, Colado MI, Naranjo JR. 1993. Molecular mechanisms of pain: serotonin1A receptor agonists trigger transactivation by c-fos of the prodynorphin gene in spinal cord neurons. Neuron 10:599-611.
30. Meller ST, Dykstra CL, Gebhart GF. 1994. Investigations of the possible role for carbon monoxide (CO) in thermal and mechanical hyperalgesia in the rat. Neuroreport 5:2337-2341.
31. Mennini T, Bigini P, Ravizza T, Vezzani A, Calvaresi N, Tortarolo M, Bendotti C. 2002. Expression of glutamate receptor subtypes in the spinal cord of control and mud mice, a model of motor neuron disorder. J Neurosci Res 70:553-560.
32. Mense S. 1983. Basic neurobiologic mechanisms of pain and analgesia. Am J Med 75:4-14.
33. Millan MJ. 1999. The induction of pain: an integrative review. Prog Neurobiol 57:1-164.
34. Molander C, Grant G. 1986. Laminar distribution and somatotopic organization of primary afferent fibers from hindlimb nerves in the dorsal horn. A study by transganglionic transport of horseradish peroxidase in the rat. Neuroscience 19:297-312.
35. Poss KD, Thomas MJ, Ebralidze AK, O'Dell TJ, Tonegawa S. 1995. Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice. Neuron 15:867-873.
36. Randic M, Jiang MC, Cerne R. 1993. Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cord. J Neurosci 13:5228-5241.
37. Rydh-Rinder M, Berge OG, Hokfelt T. 2001. Antinociceptive effects after intrathecal administration of phosphodiester-, 2′-O-allyl-, and C-5-propyne-modified antisense oligodeoxynucleotides targeting the NMDAR1 subunit in mouse. Brain Res Mol Brain Res 86:23-33.
38. South SM, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, Woolf CJ, Heinemann SF, Inturrisi CE. 2003. A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. J Neurosci 23:5031-5040.
39. Tseng SH, Chen SM, Lin SM, Huang DC. 2000. Increased immunoreactive labeling of the spinal N-methyl-D-aspartate R1 receptors after dorsal root ganglionectomy in the rats. Neurosci Lett 286:41-44.
40. Walker SM, Meredith-Middleton J, Cooke-Yarborough C, Fitzgerald M. 2003. Neonatal inflammation and primary afferent terminal plasticity in the rat dorsal horn. Pain 105:185-195.
41. Willis WD. 2002. Long-term potentiation in spinothalamic neurons. Brain Res Brain Res Rev 40:202-214.
42. Willis WD, Westlund KN. 1997. Neuroanatomy of the pain system and of the pathways that modulate pain. J Clin Neurophysiol 14:2-31.
43. Wu SX, Wang W, Wang YY, Ni TS, Li YQ, Yew DT. 2002. C-fos antisense oligodeoxynucleotide decreases subcutaneous bee venom injection-induced nociceptive behavior and fos expression in the rat. Neurosignals 11:224-230.
44. Yamamoto T, Nozaki-Taguchi N. 1995. Zinc protoporphyrin IX, an inhibitor of the enzyme that produces carbon monoxide, blocks spinal nociceptive transmission evoked by formalin injection in the rat. Brain Res 704:256-262.
45. Yukhananov R, Guan J, Crosby G. 2002. Antisense ohgonucleotides to N-methyl-D-aspartate receptor subunits attenuate formalin-induced nociception in the rat. Brain Res 930:163-169.