Carbon monoxide-induced vasorelaxation and the underlying mechanisms

British Journal of Pharmacology

Volumn 121, Issue 5, 1997, Pages 927-934

  Wang, Rui ^a   Wang, Zunzhe ^a   Wu, Lingyun ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Carbon monoxide; Contraction; CyclicGMP; Haeme oxygenase; K channels; Relaxation; Vascular smooth muscle

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CALCIUM; CARBON MONOXIDE; CYCLIC GMP; HEMIN; NITRIC OXIDE; OXYHEMOGLOBIN; PHENYLEPHRINE; POTASSIUM CHANNEL; PROTOPORPHYRIN ZINC;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TAIL ARTERY; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; ARTERIES; CALCIUM; CARBON MONOXIDE; CELL MEMBRANE; CYCLIC GMP; HEMIN; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; TAIL;

EID: 0031010733     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701222     Document Type: Article

References (30)

1. BARINAGA, M. (1993). Carbon monoxide: Killer to brain messenger in one step. Science, 259, 309.
2. CHRISTODOULIDES, N., DURANTE, W., KROLL, M.H. & SCAFER, A.I. (1995). Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation, 91, 2306-2309.
3. COBURN, R.F. (1979). Mechanisms of carbon monoxide toxicity. Prev. Med., 8, 310-322.
4. COBURN, R.F. & FORMAN, H.J. (1987). Carbon monoxide toxicity. Gas Exchange. In Handbook of Physiology, Section 3: The Respiratory System. Vol. 4. ed. Fahri, L.E. & Tenny, S.M. pp. 439-456. Bethesda. MD: American Physiological Society.
5. COCKS, T.M., KEMP, B.K., PRUNEAU, D. & ANGUS, J.A. (1993). Comparison of contractile response to 5-hydroxytryptamine and sumatriptan in human isolated coronary artery: synergy with the thromboxane A2-receptor agonist, U46619. Br. J. Pharmacol., 110, 360-368.
6. COOK, M.N., NAKATSU, K., MARKS, G.S., MCLAUGHLIN, B.E., VREMAN, H.J., STEVENSON, D.K. & BRIEN, J.F. (1995). Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation. Can. J. Physiol. Pharmacol., 73, 515-518.
7. DUKE, H. & KILLICK, E.M. (1952). Pulmonary vasomotor response of isolated perfused cat lungs to anoxia. J. Physiol., 117, 303-316.
8. FURCHGOTT, R. & JOTHIANANDAN, D. (1991). Endothelium-dependent and independent vasodilation involving cyclic GMP: Relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels, 28, 52-61.
9. GRASER, T., VEDERNIKOV, Y.P. & LI, D.S. (1990). Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein. Biomed. Biochim. Acta, 49, 293-296.
10. GRUNDEMAR, L., JOHANSSON, M., EKELUND, M. & HOGESTATT, E.D. (1995). Haem oxygenase activity in blood vessel homo-genates as measured by carbon monoxide production. Acta Physiol. Scand., 153, 203-204.
11. KIRSCHNER-ZILBER, I., RABIZADEH, E. & SHAKLAI, N. (1982). The interaction of hemin and bilirubin with the human red cell membrane. Biochim. Biophys. Acta, 690, 20-30.
12. LEVERE, R.D., MARTASEK, P., ESCALANTE, B., SCHWARTZMAN, M.L. & ABRAHAM, N.G. (1990). Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats. J. Clin. Invest., 86, 213-219.
13. LIN, H. & MCGRATH, J.J. (1989). Responses of the working rat heart to carbon monoxide. Physiol. Behaviour, 46, 81-84.
14. LIN, H. & MCGRATH, J.J. (1988). Carbon monoxide effects on calcium levels in vascular smooth muscle. Life Sci., 43, 1813-1816.
15. LINCOLN, T.M., KOMALAVILAS, P. & CORNWELL, T.L. (1994). Pleiotropic regulation of vascular smooth muscle tone by cyclic GMP-dependent protein kinase. Hypertension, 23, 1141-1147.
16. MARKS, G.S., BRIEN, J.F., NAKATSU, K. & MCLAUGHLIN, B.E. (1991). Does carbon monoxide have a physiological function? Trends Pharmacol. Sci., 12, 185-188.
17. MARTIN, W., VILLANI, G.M., JOTHIANANDAN, D. & FURCHGOTT, R.F. (1985). Blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation of rabbit aorta by certain ferrous hemoproteins. J. Pharmacol. Exp. Ther., 233, 679-685.
18. MATZ, P., TURNER, C., WEINSTEIN, P.R., MASSA, S.M. & PANTER, S.S. (1996). Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage. Brain Res., 713, 211-222.
19. MCFAUL, S.J. & MCGRATH, J.J. (1987). Studies on the mechanism of carbon monoxide-induced vasodilation in the isolated perfused rat heart. Toxicol. Appl. Pharmacol., 87, 464-473.
20. MORITA, T., PERRELLA, M.A., LEE, M.E. & KOUREMBANAS, S. (1995). Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc. Natl. Acad. Sci. USA., 92, 1475-1479.
21. NAKAZAWA, M. & IMAI, S. (1994). Rp-8-Br-guanosine-3′,5′-cyclic monophosphorothioate inhibits relaxation elicited by nitroglycerin in rabbit aorta. Eur. J. Pharmacol., 253, 179-181.
22. + pump as a site of action for carbon monoxide and glutamate: a mechanism for long-term modulation of cellular activity. Neuron, 14, 781-794.
23. RAMOS, K.S., LIN, H. & MCGRATH, J.J. (1989). Modulation of cyclic guanosine monophosphate levels in cultured aortic smooth muscle cells by carbon monoxide. Biochem. Pharmacol., 38, 1368-1370.
24. + channels. J. Physiol., 79, 259-264.
25. THUNEDBORG, P., NIELSEN, A.L., BRINKENFELDT, H., BRAHM, J. & JENSEN, H.A. (1995). Carbon monoxide in chronic uraemia related to erythroprotein treatment and smoking habits. Scand J. Urol. Nephrol., 29, 21-25.
26. TRISCHMANN, U., KLOCKNER, U., ISENBERG, G., UTZ, J. & ULLRICH, V. (1991). Carbon monoxide inhibits depolarization-induced Ca rise and increases cyclic GMP in visceral smooth muscle cells. Biochem. Pharmacol., 41, 237-241.
27. VEDERNIKOV, Y.P., GRASER, T. & VANIN, A.F. (1989). Similar endothelium-independent arterial relaxation by carbon monoxide and nitric oxide. Biomed. Biochim. Acta, 48, 595-597.
28. WANG, Z., MA, M. & WANG, R. (1996). Enhanced vasocontraction of rat tail arteries by toxoflavin. Br. J. Pharmacol., 117, 293-298.
29. YANG, F. & PHILLIPS, G.N., JR. (1996). Crystal structures of CO-, deoxy- and met-myoglobins at various pH values. J. Mol. Biol., 8, 762-774.
30. ZHUO, M., SMALL, S.A., KANDEL, E.R. & HAWKINS, R.D. (1993). Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus. Science, 260, 1946-1950.