Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Hervera, Arnau ^a   Leánez, Sergi ^a   Negrete, Roger ^a   Motterlini, Roberto ^b   Pol, Olga ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b FACULTÉ DE MÉDECINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CARBON MONOXIDE; CD11B ANTIGEN; GLYCOPROTEIN P 15095; HEME OXYGENASE 1; HEME OXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE 1; NEURONAL NITRIC OXIDE SYNTHASE 2; NITRIC OXIDE; PROTOPORPHYRIN COBALT; RUTHENIUM DERIVATIVE; TRICARBONYLCHLO (GLYCINATE)RUTHENIUM (II); TRICARBONYLDICHLORORUTHENIUM (II); UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; GENE OVEREXPRESSION; HYPERALGESIA; MALE; MICROGLIA; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PROTEIN EXPRESSION; SCIATIC NERVE INJURY; TREATMENT DURATION; WILD TYPE;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD11C; CARBON MONOXIDE; ENZYME INDUCTION; GANGLIA, SPINAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKOUT TECHNIQUES; HEME OXYGENASE-1; MALE; MICE; MICROGLIA; NEURALGIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; ORGANOMETALLIC COMPOUNDS; PYRAZINES; PYRROLES; SCIATIC NERVE; SPINAL CORD;

EID: 84865177306     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043693     Document Type: Article

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