-
2
-
-
84856511126
-
Yeast two-hybrid methods and their applications in drug discovery
-
Hamdi, A., and Colas, P. (2012) Yeast two-hybrid methods and their applications in drug discovery. Trends Pharmacol. Sci. 33, 109-118
-
(2012)
Trends Pharmacol. Sci.
, vol.33
, pp. 109-118
-
-
Hamdi, A.1
Colas, P.2
-
3
-
-
79551517793
-
Recent advances in charting protein-protein interaction: Mass spectrometry-based approaches
-
Gavin, A. C., Maeda, K., and Kuhner, S. (2011) Recent advances in charting protein-protein interaction: mass spectrometry-based approaches. Curr. Opin. Biotechnol. 22, 42-49
-
(2011)
Curr. Opin. Biotechnol.
, vol.22
, pp. 42-49
-
-
Gavin, A.C.1
Maeda, K.2
Kuhner, S.3
-
4
-
-
84862670921
-
Strategies for membrane interaction proteomics: No mass spectrometry required
-
Lam, M. H., and Stagljar, I. (2012) Strategies for membrane interaction proteomics: no mass spectrometry required. Proteomics 12, 1519-1526
-
(2012)
Proteomics
, vol.12
, pp. 1519-1526
-
-
Lam, M.H.1
Stagljar, I.2
-
5
-
-
33751547539
-
How many drug targets are there?
-
Overington, J. P., Al-Lazikani, B., and Hopkins, A. L. (2006) How many drug targets are there? Nat. Rev. Drug Discov. 5, 993-996
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 993-996
-
-
Overington, J.P.1
Al-Lazikani, B.2
Hopkins, A.L.3
-
6
-
-
34548417621
-
Fluorescent protein FRET: The good, the bad, and the ugly
-
Piston, D. W., and Kremers, G. J. (2007) Fluorescent protein FRET: the good, the bad, and the ugly. Trends Biochem. Sci. 32, 407-414
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 407-414
-
-
Piston, D.W.1
Kremers, G.J.2
-
7
-
-
33646343978
-
Illuminating insights into proteinprotein interactions using bioluminescence resonance energy transfer (BRET)
-
Pfleger, K. D., and Eidne, K. A. (2006) Illuminating insights into proteinprotein interactions using bioluminescence resonance energy transfer (BRET). Nat. Methods 3, 165-174
-
(2006)
Nat. Methods
, vol.3
, pp. 165-174
-
-
Pfleger, K.D.1
Eidne, K.A.2
-
8
-
-
84862561823
-
Diversity in genetic in vivo methods for protein-protein interaction studies: From the yeast two-hybrid system to the mammalian split-luciferase system
-
Stynen, B., Tournu, H., Tavernier, J., and Van Dijck, P. (2012) Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system. Microbiol. Mol. Biol. Rev. 76, 331-382
-
(2012)
Microbiol. Mol. Biol. Rev.
, vol.76
, pp. 331-382
-
-
Stynen, B.1
Tournu, H.2
Tavernier, J.3
Van Dijck, P.4
-
9
-
-
34347374044
-
Universal strategies in research and drug discovery based on protein-fragment complementation assays
-
Michnick, S. W., Ear, P. H., Manderson, E. N., Remy, I., and Stefan, E. (2007) Universal strategies in research and drug discovery based on protein-fragment complementation assays. Nat. Rev. Drug Discov. 6, 569-582
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 569-582
-
-
Michnick, S.W.1
Ear, P.H.2
Manderson, E.N.3
Remy, I.4
Stefan, E.5
-
10
-
-
84901847233
-
An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions
-
Tchekanda, E., Sivanesan, D., and Michnick, S. W. (2014) An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions. Nat. Methods 11, 641-644
-
(2014)
Nat. Methods
, vol.11
, pp. 641-644
-
-
Tchekanda, E.1
Sivanesan, D.2
Michnick, S.W.3
-
11
-
-
20144372620
-
High-throughput mapping of a dynamic signaling network in mammalian cells
-
Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., Shinjo, F., Liu, Y., Dembowy, J., Taylor, I. W., Luga, V., Przulj, N., Robinson, M., Suzuki, H., Hayashizaki, Y., Jurisica, I., and Wrana, J. L. (2005) High-throughput mapping of a dynamic signaling network in mammalian cells. Science 307, 1621-1625
-
(2005)
Science
, vol.307
, pp. 1621-1625
-
-
Barrios-Rodiles, M.1
Brown, K.R.2
Ozdamar, B.3
Bose, R.4
Liu, Z.5
Donovan, R.S.6
Shinjo, F.7
Liu, Y.8
Dembowy, J.9
Taylor, I.W.10
Luga, V.11
Przulj, N.12
Robinson, M.13
Suzuki, H.14
Hayashizaki, Y.15
Jurisica, I.16
Wrana, J.L.17
-
12
-
-
84899903279
-
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
-
Petschnigg, J., Groisman, B., Kotlyar, M., Taipale, M., Zheng, Y., Kurat, C. F., Sayad, A., Sierra, J. R., Mattiazzi Usaj, M., Snider, J., Nachman, A., Krykbaeva, I., Tsao, M. S., Moffat, J., Pawson, T., Lindquist, S., Jurisica, I., and Stagljar, I. (2014) The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat. Methods 11, 585-592
-
(2014)
Nat. Methods
, vol.11
, pp. 585-592
-
-
Petschnigg, J.1
Groisman, B.2
Kotlyar, M.3
Taipale, M.4
Zheng, Y.5
Kurat, C.F.6
Sayad, A.7
Sierra, J.R.8
Mattiazzi Usaj, M.9
Snider, J.10
Nachman, A.11
Krykbaeva, I.12
Tsao, M.S.13
Moffat, J.14
Pawson, T.15
Lindquist, S.16
Jurisica, I.17
Stagljar, I.18
-
13
-
-
79960245388
-
Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor
-
Bisson, N., James, D. A., Ivosev, G., Tate, S. A., Bonner, R., Taylor, L., and Pawson, T. (2011) Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. Nat. Biotechnol. 29, 653-658
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 653-658
-
-
Bisson, N.1
James, D.A.2
Ivosev, G.3
Tate, S.A.4
Bonner, R.5
Taylor, L.6
Pawson, T.7
-
14
-
-
84888858053
-
Quantifying protein interaction dynamics by SWATH mass spectrometry: Application to the 14-3-3 system
-
Collins, B. C., Gillet, L. C., Rosenberger, G., Rost, H. L., Vichalkovski, A., Gstaiger, M., and Aebersold, R. (2013) Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system. Nat. Methods 10, 1246-1253
-
(2013)
Nat. Methods
, vol.10
, pp. 1246-1253
-
-
Collins, B.C.1
Gillet, L.C.2
Rosenberger, G.3
Rost, H.L.4
Vichalkovski, A.5
Gstaiger, M.6
Aebersold, R.7
-
15
-
-
0035199166
-
Design and application of a cytokine-receptor-based interaction trap
-
Eyckerman, S., Verhee, A., Van der Heyden, J. V., Lemmens, I., Van Ostade, X. V., Vandekerckhove, J., and Tavernier, J. (2001) Design and application of a cytokine-receptor-based interaction trap. Nat. Cell Biol. 3, 1114-1119
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 1114-1119
-
-
Eyckerman, S.1
Verhee, A.2
Van Der Heyden, J.V.3
Lemmens, I.4
Van Ostade, X.V.5
Vandekerckhove, J.6
Tavernier, J.7
-
16
-
-
82955163295
-
MAPPIT: A protein interaction toolbox built on insights in cytokine receptor signaling
-
Lievens, S., Peelman, F., De Bosscher, K., Lemmens, I., and Tavernier, J. (2011) MAPPIT: a protein interaction toolbox built on insights in cytokine receptor signaling. Cytokine Growth Factor Rev. 22, 321-329
-
(2011)
Cytokine Growth Factor Rev.
, vol.22
, pp. 321-329
-
-
Lievens, S.1
Peelman, F.2
De Bosscher, K.3
Lemmens, I.4
Tavernier, J.5
-
17
-
-
58149242456
-
An experimentally derived confidence score for binary protein-protein interactions
-
Braun, P., Tasan, M., Dreze, M., Barrios-Rodiles, M., Lemmens, I., Yu, H., Sahalie, J. M., Murray, R. R., Roncari, L., de Smet, A. S., Venkatesan, K., Rual, J. F., Vandenhaute, J., Cusick, M. E., Pawson, T., Hill, D. E., Tavernier, J., Wrana, J. L., Roth, F. P., and Vidal, M. (2009) An experimentally derived confidence score for binary protein-protein interactions. Nat. Methods 6, 91-97
-
(2009)
Nat. Methods
, vol.6
, pp. 91-97
-
-
Braun, P.1
Tasan, M.2
Dreze, M.3
Barrios-Rodiles, M.4
Lemmens, I.5
Yu, H.6
Sahalie, J.M.7
Murray, R.R.8
Roncari, L.9
De Smet, A.S.10
Venkatesan, K.11
Rual, J.F.12
Vandenhaute, J.13
Cusick, M.E.14
Pawson, T.15
Hill, D.E.16
Tavernier, J.17
Wrana, J.L.18
Roth, F.P.19
Vidal, M.20
more..
-
18
-
-
84885183894
-
The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response
-
Simicek, M., Lievens, S., Laga, M., Guzenko, D., Aushev, V. N., Kalev, P., Baietti, M. F., Strelkov, S. V., Gevaert, K., Tavernier, J., and Sablina, A. A. (2013) The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response. Nat. Cell Biol. 15, 1220-1230
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 1220-1230
-
-
Simicek, M.1
Lievens, S.2
Laga, M.3
Guzenko, D.4
Aushev, V.N.5
Kalev, P.6
Baietti, M.F.7
Strelkov, S.V.8
Gevaert, K.9
Tavernier, J.10
Sablina, A.A.11
-
19
-
-
21444437387
-
Reverse MAPPIT: Screening for protein-protein interaction modifiers in mammalian cells
-
Eyckerman, S., Lemmens, I., Catteeuw, D., Verhee, A., Vandekerckhove, J., Lievens, S., and Tavernier, J. (2005) Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells. Nat. Methods 2, 427-433
-
(2005)
Nat. Methods
, vol.2
, pp. 427-433
-
-
Eyckerman, S.1
Lemmens, I.2
Catteeuw, D.3
Verhee, A.4
Vandekerckhove, J.5
Lievens, S.6
Tavernier, J.7
-
20
-
-
84872422654
-
The use of mammalian two-hybrid technologies for high-throughput drug screening
-
Lievens, S., Caligiuri, M., Kley, N., and Tavernier, J. (2012) The use of mammalian two-hybrid technologies for high-throughput drug screening. Methods 58, 335-342
-
(2012)
Methods
, vol.58
, pp. 335-342
-
-
Lievens, S.1
Caligiuri, M.2
Kley, N.3
Tavernier, J.4
-
21
-
-
84874315356
-
A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT
-
Risseeuw, M. D., De Clercq, D. J., Lievens, S., Hillaert, U., Sinnaeve, D., Van den Broeck, F., Martins, J. C., Tavernier, J., and Van Calenbergh, S. (2013) A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT. Chem. Med. Chem. 8, 521-526
-
(2013)
Chem. Med. Chem.
, vol.8
, pp. 521-526
-
-
Risseeuw, M.D.1
De Clercq, D.J.2
Lievens, S.3
Hillaert, U.4
Sinnaeve, D.5
Van Den Broeck, F.6
Martins, J.C.7
Tavernier, J.8
Van Calenbergh, S.9
-
22
-
-
33746329294
-
MASPIT: Three-hybrid trap for quantitative proteome fingerprinting of small molecule-protein interactions in mammalian cells
-
Caligiuri, M., Molz, L., Liu, Q., Kaplan, F., Xu, J. P., Majeti, J. Z., Ramos-Kelsey, R., Murthi, K., Lievens, S., Tavernier, J., and Kley, N. (2006) MASPIT: three-hybrid trap for quantitative proteome fingerprinting of small molecule-protein interactions in mammalian cells. Chem. Biol. 13, 711-722
-
(2006)
Chem. Biol.
, vol.13
, pp. 711-722
-
-
Caligiuri, M.1
Molz, L.2
Liu, Q.3
Kaplan, F.4
Xu, J.P.5
Majeti, J.Z.6
Ramos-Kelsey, R.7
Murthi, K.8
Lievens, S.9
Tavernier, J.10
Kley, N.11
-
23
-
-
61849088451
-
Array MAPPIT: High-throughput interactome analysis in mammalian cells
-
Lievens, S., Vanderroost, N., Van der Heyden, J., Gesellchen, V., Vidal, M., and Tavernier, J. (2009) Array MAPPIT: high-throughput interactome analysis in mammalian cells. J. Proteome Res. 8, 877-886
-
(2009)
J. Proteome Res.
, vol.8
, pp. 877-886
-
-
Lievens, S.1
Vanderroost, N.2
Van Der Heyden, J.3
Gesellchen, V.4
Vidal, M.5
Tavernier, J.6
-
24
-
-
0036069980
-
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
-
Shen, J., Chen, X., Hendershot, L., and Prywes, R. (2002) ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev. Cell 3, 99-111
-
(2002)
Dev. Cell
, vol.3
, pp. 99-111
-
-
Shen, J.1
Chen, X.2
Hendershot, L.3
Prywes, R.4
-
25
-
-
33644683832
-
Effects of efavirenz binding on the subunit equilibria of HIV-1 reverse transcriptase
-
Venezia, C. F., Howard, K. J., Ignatov, M. E., Holladay, L. A., and Barkley, M. D. (2006) Effects of efavirenz binding on the subunit equilibria of HIV-1 reverse transcriptase. Biochemistry 45, 2779-2789
-
(2006)
Biochemistry
, vol.45
, pp. 2779-2789
-
-
Venezia, C.F.1
Howard, K.J.2
Ignatov, M.E.3
Holladay, L.A.4
Barkley, M.D.5
-
26
-
-
77952415656
-
Beyond desensitization: Physiological relevance of arrestin-dependent signaling
-
Luttrell, L. M., and Gesty-Palmer, D. (2010) Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol. Rev. 62, 305-330
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 305-330
-
-
Luttrell, L.M.1
Gesty-Palmer, D.2
-
27
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon, W., Welihinda, A. A., and Kaufman, R. J. (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev. 12, 1812-1824
-
(1998)
Genes Dev.
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
28
-
-
84870915654
-
Modeling transcriptome dynamics in a complex world
-
Jaeger, P. A., Doherty, C., and Ideker, T. (2012) Modeling transcriptome dynamics in a complex world. Cell 151, 1161-1162
-
(2012)
Cell
, vol.151
, pp. 1161-1162
-
-
Jaeger, P.A.1
Doherty, C.2
Ideker, T.3
-
29
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti, A., Zhang, Y., Hendershot, L. M., Harding, H. P., and Ron, D. (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol. 2, 326-332
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
30
-
-
84870159094
-
Structural basis of the unfolded protein response
-
Korennykh, A., and Walter, P. (2012) Structural basis of the unfolded protein response. Annu. Rev. Cell Dev. Biol. 28, 251-277
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 251-277
-
-
Korennykh, A.1
Walter, P.2
-
31
-
-
33749233991
-
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
-
Zhou, J., Liu, C. Y., Back, S. H., Clark, R. L., Peisach, D., Xu, Z., and Kaufman, R. J. (2006) The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc. Natl. Acad. Sci. U. S. A. 103, 14343-14348
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 14343-14348
-
-
Zhou, J.1
Liu, C.Y.2
Back, S.H.3
Clark, R.L.4
Peisach, D.5
Xu, Z.6
Kaufman, R.J.7
-
32
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., Fotouhi, N., and Liu, E. A. (2004) In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303, 844-848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
33
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf, T., Elmore, S. W., Shoemaker, A. R., Armstrong, R. C., Augeri, D. J., Belli, B. A., Bruncko, M., Deckwerth, T. L., Dinges, J., Hajduk, P. J., Joseph, M. K., Kitada, S., Korsmeyer, S. J., Kunzer, A. R., Letai, A., Li, C., Mitten, M. J., Nettesheim, D. G., Ng, S., Nimmer, P. M., O'Connor, J. M., Oleksijew, A., Petros, A. M., Reed, J. C., Shen, W., Tahir, S. K., Thompson, C. B., Tomaselli, K. J., Wang, B., Wendt, M. D., Zhang, H., Fesik, S. W., and Rosenberg, S. H. (2005) An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435, 677-681
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
34
-
-
17644399461
-
Telmisartan has the strongest binding affinity to angiotensin II type 1 receptor: Comparison with other angiotensin II type 1 receptor blockers
-
Kakuta, H., Sudoh, K., Sasamata, M., and Yamagishi, S. (2005) Telmisartan has the strongest binding affinity to angiotensin II type 1 receptor: comparison with other angiotensin II type 1 receptor blockers. Int. J. Clin. Pharmacol. Res. 25, 41-46
-
(2005)
Int. J. Clin. Pharmacol. Res.
, vol.25
, pp. 41-46
-
-
Kakuta, H.1
Sudoh, K.2
Sasamata, M.3
Yamagishi, S.4
-
35
-
-
0038004785
-
Lovastatin and beyond: The history of the HMG-CoA reductase inhibitors
-
Tobert, J. A. (2003) Lovastatin and beyond: The history of the HMG-CoA reductase inhibitors. Nat. Rev. Drug Discov. 2, 517-526
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 517-526
-
-
Tobert, J.A.1
-
36
-
-
84872821321
-
Dissection of DNA damage responses using multiconditional genetic interaction maps
-
Guenole, A., Srivas, R., Vreeken, K., Wang, Z. Z., Wang, S., Krogan, N. J., Ideker, T., and van Attikum, H. (2013) Dissection of DNA damage responses using multiconditional genetic interaction maps. Mol. Cell 49, 346-358
-
(2013)
Mol. Cell
, vol.49
, pp. 346-358
-
-
Guenole, A.1
Srivas, R.2
Vreeken, K.3
Wang, Z.Z.4
Wang, S.5
Krogan, N.J.6
Ideker, T.7
Van Attikum, H.8
-
37
-
-
77956321519
-
Exhaustive benchmarking of the yeast two-hybrid system
-
author reply, 668
-
Chen, Y. C., Rajagopala, S. V., Stellberger, T., and Uetz, P. (2010) Exhaustive benchmarking of the yeast two-hybrid system. Nat. Methods 7, 667-668, author reply, 668
-
(2010)
Nat. Methods
, vol.7
, pp. 667-668
-
-
Chen, Y.C.1
Rajagopala, S.V.2
Stellberger, T.3
Uetz, P.4
-
38
-
-
49349104466
-
MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells
-
Pattyn, E., Lavens, D., Van der Heyden, J., Verhee, A., Lievens, S., Lemmens, I., Hallenberger, S., Jochmans, D., and Tavernier, J. (2008) MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells. J. Virol. Methods 153, 7-15
-
(2008)
J. Virol. Methods
, vol.153
, pp. 7-15
-
-
Pattyn, E.1
Lavens, D.2
Van Der Heyden, J.3
Verhee, A.4
Lievens, S.5
Lemmens, I.6
Hallenberger, S.7
Jochmans, D.8
Tavernier, J.9
-
39
-
-
84891850975
-
Targeting protein-protein interaction by small molecules
-
Jin, L., Wang, W., and Fang, G. (2014) Targeting protein-protein interaction by small molecules. Annu. Rev. Pharmacol. Toxicol. 54, 435-456
-
(2014)
Annu. Rev. Pharmacol. Toxicol.
, vol.54
, pp. 435-456
-
-
Jin, L.1
Wang, W.2
Fang, G.3
-
40
-
-
35748983210
-
Target deconvolution strategies in drug discovery
-
Terstappen, G. C., Schlupen, C., Raggiaschi, R., and Gaviraghi, G. (2007) Target deconvolution strategies in drug discovery. Nat. Rev. Drug Discov. 6, 891-903
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 891-903
-
-
Terstappen, G.C.1
Schlupen, C.2
Raggiaschi, R.3
Gaviraghi, G.4
-
41
-
-
75149125686
-
Recent advances and method development for drug target identification
-
Chan, J. N., Nislow, C., and Emili, A. (2010) Recent advances and method development for drug target identification. Trends Pharmacol. Sci. 31, 82-88
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 82-88
-
-
Chan, J.N.1
Nislow, C.2
Emili, A.3
-
42
-
-
85027931231
-
A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis
-
Chidley, C., Haruki, H., Pedersen, M. G., Muller, E., and Johnsson, K. (2011) A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis. Nat. Chem. Biol. 7, 375-383
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 375-383
-
-
Chidley, C.1
Haruki, H.2
Pedersen, M.G.3
Muller, E.4
Johnsson, K.5
|