Effects of efavirenz binding on the subunit equilibria of HIV-1 reverse transcriptase

Biochemistry

Volumn 45, Issue 9, 2006, Pages 2779-2789

  Venezia, Carl F ^a   Howard, Kathryn J ^b   Ignatov, Michael E ^b   Holladay, Leslie A ^c   Barkley, Mary D ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERIZATION; DISSOCIATION; ENZYME INHIBITION; HEALTH; MIXTURES; SEDIMENTATION; THERMODYNAMIC PROPERTIES;

ANTI-RETROVIRAL THERAPY; HIV-1; REVERSE TRANSCRIPTASE;

ENZYMES;

EFAVIRENZ; PROTEIN P51; PROTEIN P66; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CRYSTAL STRUCTURE; DIMERIZATION; DISSOCIATION CONSTANT; ENZYME BINDING; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR MODEL; PRIORITY JOURNAL; REACTION ANALYSIS; SEDIMENTATION; STRUCTURE ANALYSIS;

BINDING SITES; DIMERIZATION; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; OXAZINES; PROTEIN CONFORMATION; PROTEIN SUBUNITS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33644683832     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051915z     Document Type: Article

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